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HIV-1 Viral loas assays for resource-limited settings
Fiscus, Susan A. (University of North Carolina at Chapel Hill (Estats Units d'Amèrica))
Cheng, Ben (Forum for Collaborative HIV Research (Washington, Estats Units d'Amèrica))
Crowe, Suzanne M. (Macfarlane Burnet Institute for Medical Research and Public Health (Melbourne, Austràlia))
Demeter, Lisa (University of Rochester School of Medicine and Dentistry (Rochester, Estats Units d'Amèrica))
Jennings, Cheryl (Rush University Medical Center (Chicago, Estats Units d'Amèrica))
Miller, Veronica (Forum for Collaborative HIV Research (Washington, Estats Units d'Amèrica))
Respess, Richard (Centers for Disease Control and Prevention (Atlanta, Estats Units d'Amèrica))
Stevens, Wendy (University of the Witwatersrand (Johannesburg, Sud-àfrica))
Martínez Picado, Francisco Javier (Universitat Autònoma de Barcelona)
Forum for Collaborative HIV Research Alternative Viral Load Assay Working Group

Date: 2006
Abstract: Tremendous strides have been made in treating HIV-1 infection in industrialized countries. Combination therapy with antiretroviral (ARV) drugs suppresses virus replication, delays disease progression, and reduces mortality. In industrialized settings, plasma viral load assays are used in combination with CD4 cell counts to determine when to initiate therapy and when a regimen is failing. In addition, unlike serologic assays, these assays may be used to diagnose perinatal or acute HIV-1 infection. Unfortunately, the full benefits of antiretroviral drugs and monitoring tests have not yet reached the majority of HIV-1-infected patients who live in countries with limited resources. In this article we discuss existing data on the performance of alternative viral load assays that might be useful in resource-limited settings.
Rights: Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. Creative Commons
Language: Anglès
Document: Article ; Versió publicada
Subject: HIV-1 ; Enzyme-linked immunoassays ; Blood plasma ; Antigens ; Viral load
Published in: PLoS medicine, Vol. 3, Issue 10 (October 2006) , p.e417, ISSN 1549-1277

DOI: 10.1371/journal.pmed.0030417
PMID: 17032062


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 Record created 2013-10-14, last modified 2022-03-30



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