Decoding of grasping information from neural signals recorded using peripheral intrafascicular interfaces
Micera, Silvestro (Swiss Federal Institute of Technology (Zuric, Suïssa))
Rossini, Paolo M. (Casa di Cura S. Raffaele (Roma, Itàlia))
Rigosa, Jacopo (Swiss Federal Institute of Technology (Zuric, Suïssa))
Citi, Luca (Swiss Federal Institute of Technology (Zuric, Suïssa))
Carpaneto, Jacopo (Swiss Federal Institute of Technology (Zuric, Suïssa))
Raspopovic, Stanisa (Swiss Federal Institute of Technology (Zuric, Suïssa))
Tombini, Mario (Campus Biomedico University (Roma, Itàlia))
Cipriani, Christian (Swiss Federal Institute of Technology (Zuric, Suïssa))
Assenza, Giovanni (Campus Biomedico University (Roma, Itàlia))
Carrozza, Maria C. (Swiss Federal Institute of Technology (Zuric, Suïssa))
Hoffmann, Klaus-Peter (Fraunhofer Institute for Biomedical Engineering (St. Ingbert, Alemanya))
Yoshida, Ken (Indiana University-Purdue University (Indianapolis, Estats Units d'Amèrica))
Navarro, X. (Xavier) (Xavier) (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Dario, Paolo (Swiss Federal Institute of Technology (Zuric, Suïssa))

Date:	2011
Abstract:	Background: The restoration of complex hand functions by creating a novel bidirectional link between the nervous system and a dexterous hand prosthesis is currently pursued by several research groups. This connection must be fast, intuitive, with a high success rate and quite natural to allow an effective bidirectional flow of information between the user's nervous system and the smart artificial device. This goal can be achieved with several approaches and among them, the use of implantable interfaces connected with the peripheral nervous system, namely intrafascicular electrodes, is considered particularly interesting. Methods: Thin-film longitudinal intra-fascicular electrodes were implanted in the median and ulnar nerves of an amputee's stump during a four-week trial. The possibility of decoding motor commands suitable to control a dexterous hand prosthesis was investigated for the first time in this research field by implementing a spike sorting and classification algorithm. Results: The results showed that motor information (e. g. , grip types and single finger movements) could be extracted with classification accuracy around 85% (for three classes plus rest) and that the user could improve his ability to govern motor commands over time as shown by the improved discrimination ability of our classification algorithm. Conclusions: These results open up new and promising possibilities for the development of a neuro-controlled hand prosthesis.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; Versió publicada
Published in:	Journal of neuroengineering and rehabilitation, Vol. 8, Num. 53 (September 2011) , p. 53, ISSN 1743-0003

DOI: 10.1186/1743-0003-8-53
PMID: 21892926
PMID: 20423488

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