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Caracterización clínica y electrofisiológica de las alteraciones recíprocas del electrocardiograma en el infarto agudo de miocardio
Noriega Sanz, Francisco Javier
Cinca Cuscullola, Juan María, dir.
Universitat Autònoma de Barcelona. Departament de Medicina

Publicació: [Barcelona] : Universitat Autònoma de Barcelona, 2015
Descripció: 1 recurs electrònic (103 p.)
Resum: Transmural myocardial ischemia induced by acute coronary artery occlusion induces electric and metabolic changes in myocardial cells caused by the interruption of coronary blood flow. These changes are recorded in the conventional electrocardiogram (ECG) as ST segment elevation in leads directly related to the ischemic region, and they allow to predict the location of the coronary artery occlusion. In addition, reciprocal ST segment depression could be present in ECG leads overlying distant non ischemic areas. The electrophysiologic mechanism and clinical implications of these reciprocal changes are not well known. This thesis consists of three translational studies which analyze the reciprocal ECG changes in the onset of an acute myocardial infarction due to a coronary artery occlusion. The experimental studies are developed in a porcine model of myocardial ischemia. The clinical study included patients with an acute myocardial infarction submitted to primary coronary reperfusion. Results from these studies allow to get insight into the electrophysiologic characterization of reciprocal ST segment changes, which are not caused by added subendocardial ischemia at a distance, but related to the ECG lead system design. Moreover, the combined analyses of direct and reciprocal ST segment changes predicts more accurately the location of the coronary artery occlusion, being the ECG patterns also valid in patients with multivessel coronary artery disease.
Nota: Tesi doctoral - Universitat Autònoma de Barcelona. Departament de Medicina, 2015
Drets: L'accés als continguts d'aquesta tesi queda condicionat a l'acceptació de les condicions d'ús establertes per la següent llicència Creative Commons Creative Commons
Llengua: Castellà.
Document: Tesis i dissertacions electròniques ; doctoralThesis ; publishedVersion
Matèria: Infarto agudo de miocardio ; Electrocardiograma ; Cambios recíproco
ISBN: 9788449054921

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103 p, 2.0 MB

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