Per citar aquest document: http://ddd.uab.cat/record/142539
Relationship between Physical Activity and Plasma Fibrinogen Concentrations in Adults without Chronic Diseases
Gomez Marcos, Manuel (Universidad de Salamanca. Departamento de Medicina)
Recio Rodríguez, Jose I. (Centro de salud La Alamedilla (Salamanca, Castella i Lleó))
Patino Alonso, María C. (Universidad de Salamanca. Departamento de Estadística)
Martinez Vizcaino, Vicente (Universidad de Castilla-La Mancha. Centro de Investigación de Atención Social y Sanitaria)
Martín Borràs, Carme (Universitat Ramon Llull. Departament de Ciències de l'activitat física i de l'esport)
De la Cal de la Fuente, Aventina (Centro de Salud Casa de Barco (Valladolid, Castella i Lleó))
Sauras Llera, Ines (Centro de Salud Torre Ramona (Saragossa, Aragó))
Sanchez Perez, Álvaro (Servicio Vasco de Salud Osakidetza)
Agudo Conde, Cristina (Centro de salud La Alamedilla (Salamanca, Castella i Lleó))
García Ortiz, Luís (Centro de salud La Alamedilla (Salamanca, Castella i Lleó))

Data: 2014
Resum: Objective: to analyze the relationship between regular physical activity, as assessed by accelerometer and 7-day physical activity recall (PAR), and plasma fibrinogen concentrations. Methods: a cross-sectional study in a previously established cohort of healthy subjects was performed. This study analyzed 1284 subjects who were included in the EVIDENT study (mean age 55. 0±13. 6 years; 60. 90% women). Fibrinogen concentrations were measured in blood plasma. Physical activity was assessed with a 7-day PAR (metabolic equivalents (METs)/hour/week) and GT3X ActiGraph accelerometer (counts/minute) for 7 days. Results: physical exercise, which was evaluated with both an accelerometer (Median: 237. 28 counts/minute) and 7-day PAR (Median: 8 METs/hour/week). Physical activity was negatively correlated with plasma fibrinogen concentrations, which was evaluated by counts/min (r = −0. 100; p<0. 001) and METs/hour/week (r = −0. 162; p<0. 001). In a multiple linear regression analysis, fibrinogen concentrations of the subjects who performed more physical activity (third tertile of count/minute and METs/hour/week) respect to subjects who performed less (first tertile), maintained statistical significance after adjustments for age and others confounders (β = −0. 03; p = 0. 046 and β = −0. 06; p<0. 001, respectively). Conclusions: Physical activity, as assessed by accelerometer and 7-day PAR, was negatively associated with plasma fibrinogen concentrations. This relation is maintained in subjects who performed more exercise even after adjusting for age and other confounders.
Drets: Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. Creative Commons
Llengua: Anglès
Document: article ; recerca ; publishedVersion
Matèria: Fibrinogen ; Accelerometers ; Blood plasma ; Blood pressure ; Blood counts ; Cholesterol ; Exercise ; Alcohol consumption
Publicat a: PLoS one, Vol. 9 Issue 2 (February 2014) , p. e87954, ISSN 1932-6203

DOI: 10.1371/journal.pone.0087954


7 p, 323.1 KB

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