97784 articleid 16962281v32n2p151 eng Ocaña, Jordi Universitat de Barcelona On equivalence and bioequivalence testing Equivalence testing is the natural approach to many statistical problems. First, its main application, bioequivalence testing, is reviewed. The basic concepts of bioequivalence testing (2×2 crossover designs, TOST, interval inclusion principle, etc.) and its problems (TOST biased character, the carryover problem, etc.) are considered. Next, equivalence testing is discussed more generally. Some applications and methods are reviewed and the relation of equivalence testing and distance-based inference is highlighted. A new distance-based method to determine whether two gene lists are equivalent in terms of their annotations in the Gene Ontology illustrates these ideas. We end with a general discussion and some suggestions for future research. Tots els drets reservats http://www.europeana.eu/rights/rr-f/ Anglès Article de fons Crossover designs TOST Intersection-union Distance-based inference Validation of simulation models Gene Ontology info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Sánchez, M. Pilar Universidad de Chile Sánchez, Álex Universitat de Barcelona Carrasco, Josep Lluís Universitat de Barcelona Vol. 32, Núm. 2 (July-December 2008), p. 151-176 SORT : statistics and operations research transactions 1696-2281 26 545884 http://ddd.uab.cat/uab/sort/sort_a2008m7-12v32n2/sort_a2008m7-12v32n2p151.pdf 0151 176 July-December 2 32 sort_a2008m7-12v32n2 2008 ARTPUB UAB SORT artpubuab oai:ddd.uab.cat:97784 driver