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14 p, 1.9 MB Assessing the structural conservation of protein pockets to study functional and allosteric sites: implications for drug discovery / Panjkovich, Alejandro (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Daura i Ribera, Xavier (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
Background: With the classical, active-site oriented drug-development approach reaching its limits, protein ligand-binding sites in general and allosteric sites in particular are increasingly attracting the interest of medicinal chemists in the search for new types of targets and strategies to drug development. [...]
2010 - 10.1186/1472-6807-10-9
BMC Structural biology, Vol. 10, Núm. 9 (March 2010) , p. 9-9  

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