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Articles 2 registres trobats  
1.
12 p, 3.2 MB Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type / Karnezis, Anthony N. (University of British Columbia. Department of Pathology and Laboratory Medicine) ; Wang, Yemin (University of British Columbia. Department of Pathology and Laboratory Medicine) ; Ramos, Pilar (Translational Genomics Research Institute) ; Hendricks, William P. D. (Translational Genomics Research Institute) ; Oliva, Esther (Massachusetts General Hospital (Boston)) ; D'Angelo, Emanuela (Institut d'Investigació Biomèdica Sant Pau) ; Prat, Jaime (Institut d'Investigació Biomèdica Sant Pau) ; Nucci, Marisa R. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ; Nielsen, Torsten O. (University of British Columbia. Department of Pathology and Laboratory Medicine) ; Chow, Christine (University of British Columbia. Genetic Pathology Evaluation Centre) ; Leung, Samuel (University of British Columbia. Genetic Pathology Evaluation Centre) ; Kommoss, Friedrich (Synlab MVZ Pathologie) ; Kommoss, Stefan (University Hospital of Tübingen (Alemanya)) ; Silva, Annacarolina (Harvard Medical School. The James Homer Wright Pathology Laboratories) ; Ronnett, Brigitte M. (The Johns Hopkins Hospital. Department of Pathology) ; Rabban, Joseph T. (University of California San Francisco. Department of Anatomic Pathology) ; Bowtell, David D. (Peter MacCallum Cancer Centre) ; Weissman, Bernard E. (University of North Carolina. Department of Pathology and Laboratory Medicine) ; Trent, Jeffrey M. (Translational Genomics Research Institute) ; Gilks, C. Blake (University of British Columbia. Department of Pathology and Laboratory Medicine) ; Huntsman, David G. (University of British Columbia. Department of Pathology and Laboratory Medicine) ; Universitat Autònoma de Barcelona
Small cell carcinoma of the ovary, hypercalcaemic type () is a lethal and sometimes familial ovarian tumour of young women and children. We and others recently discovered that over 90% of harbour inactivating mutations in the chromatin remodelling gene with concomitant loss of its encoded protein (), one of two mutually exclusive of the / chromatin remodelling complex. [...]
2015 - 10.1002/path.4633
The Journal of Pathology, Vol. 238, Issue 3 (december 2015) , p. 389-400  
2.
12 p, 915.6 KB PAM50 breast cancer subtyping by RT-qPCR and concordance with standard clinical molecular markers / Bastien, Roy R. L. (The ARUP Institute for Clinical and Experimental Pathology (Salt Lake City, Estats Units d'Amèrica)) ; Rodríguez-Lescure, Álvaro (Hospital General Universitario de Elche) ; Ebbert, Mark T. W. (The ARUP Institute for Clinical and Experimental Pathology (Salt Lake City, Estats Units d'Amèrica)) ; Prat, Aleix (Universitat Autònoma de Barcelona. Departament de Medicina) ; Munárriz, Blanca (Hospital Universitari i Politècnic La Fe (València)) ; Rowe, Leslie (The ARUP Institute for Clinical and Experimental Pathology (Salt Lake City, Estats Units d'Amèrica)) ; Miller, Patricia (The ARUP Institute for Clinical and Experimental Pathology (Salt Lake City, Estats Units d'Amèrica)) ; Ruiz Borrego, Manuel (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Anderson, Daniel (The ARUP Institute for Clinical and Experimental Pathology (Salt Lake City, Estats Units d'Amèrica)) ; Lyons, Bradley (The ARUP Institute for Clinical and Experimental Pathology (Salt Lake City, Estats Units d'Amèrica)) ; Álvarez López, Isabel (Hospital Universitario de Donostia (Sant Sebastià, País Basc)) ; Dowell, Tracy (The ARUP Institute for Clinical and Experimental Pathology (Salt Lake City, Estats Units d'Amèrica)) ; Wall, David (The ARUP Institute for Clinical and Experimental Pathology (Salt Lake City, Estats Units d'Amèrica)) ; Seguí, Miguel Ángel (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Barley, Lee (The ARUP Institute for Clinical and Experimental Pathology (Salt Lake City, Estats Units d'Amèrica)) ; Boucher, Kenneth M. (Huntsman Cancer Institute (Salt Lake City, Estats Units d'Amèrica)) ; Alba, Emilio (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia)) ; Pappas, Lisa (Huntsman Cancer Institute (Salt Lake City, Estats Units d'Amèrica)) ; Davis, Carole A. (Huntsman Cancer Institute (Salt Lake City, Estats Units d'Amèrica)) ; Aranda, Ignacio (Hospital General Universitario de Alicante (Alacant, País Valencià)) ; Fauron, Christiane (The ARUP Institute for Clinical and Experimental Pathology (Salt Lake City, Estats Units d'Amèrica)) ; Stijleman, Inge J. (Huntsman Cancer Institute (Salt Lake City, Estats Units d'Amèrica)) ; Palacios, José (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Antón, Antonio (Hospital Universitario Miguel Servet (Saragossa)) ; Carrasco, Eva (GEICAM. Spanish Breast Cancer Research Group (Madrid)) ; Caballero, Rosalía (GEICAM. Spanish Breast Cancer Research Group (Madrid)) ; Ellis, Matthew J. (Washington University. Department of Oncology (St. Louis, Estats Units d'Amèrica)) ; Nielsen, Torsten O. (University of British Columbia. Department of Anatomical Pathology (Vancouver, Canadà)) ; Perou, Charles M. (University of North Carolina at Chapel Hill. Lineberger Comprehensive Cancer Center (Chapel Hill, Estats Units d'Amèrica)) ; Astill, Mark (The ARUP Institute for Clinical and Experimental Pathology (Salt Lake City, Estats Units d'Amèrica)) ; Bernard, Philip S. (Huntsman Cancer Institute (Salt Lake City, Estats Units d'Amèrica)) ; Martín Jiménez, Miguel (Hospital General Universitario Gregorio Marañón)
Background: Many methodologies have been used in research to identify the "intrinsic" subtypes of breast cancer commonly known as Luminal A, Luminal B, HER2-Enriched (HER2-E) and Basal-like. The PAM50 gene set is often used for gene expression-based subtyping; however, surrogate subtyping using panels of immunohistochemical (IHC) markers are still widely used clinically. [...]
2012 - 10.1186/1755-8794-5-44
BMC medical genomics, Vol. 15, N. 44 (October 2012) , p. 1-9
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