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9 p, 241.0 KB |
Surviving rectal cancer at the cost of a colostomy : global survey of long-term health-related quality of life in 10 countries
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Kristensen, Helle Ø ;
Thyø, Anne ;
Emmertsen, Katrine J ;
Smart, Neil J ;
Pinkney, Thomas ;
Warwick, Andrea M ;
Pang, Dong ;
Elfeki, Hossam ;
Shalaby, Mostafa ;
Emile, Sameh H ;
Abdelkhalek, Mohamed ;
Zuhdy, Mohammad ;
Poskus, Tomas ;
Dulskas, Audrius ;
Horesh, Nir ;
Furnée, Edgar J B ;
Verkuijl, Sanne J ;
Rama, Nuno José ;
Domingos, Hugo ;
Maciel, João ;
Solis-Peña, Alejandro (Hospital Universitari Vall d'Hebron) ;
Espin-Basany, Eloy (Hospital Universitari Vall d'Hebron) ;
Hidalgo-Pujol, Marta (Hospital Universitari de Bellvitge) ;
Biondo, Sebastiano (Hospital Universitari de Bellvitge) ;
Sjövall, Annika ;
Christensen, Peter ;
Universitat Autònoma de Barcelona
Colorectal cancer management may require an ostomy formation; however, a stoma may negatively impact health-related quality of life (HRQoL). This study aimed to compare generic and stoma-specific HRQoL in patients with a permanent colostomy after rectal cancer across different countries. [...]
2022 -  10.1093/bjsopen/zrac085
BJS Open, Vol. 6 (december 2022)
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2.
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11 p, 2.6 MB |
Knock-Out of CmNAC-NOR Affects Melon Climacteric Fruit Ripening
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Liu, Bin (Centre de Recerca en Agrigenòmica) ;
Santo Domingo, Miguel (Centre de Recerca en Agrigenòmica) ;
Mayobre, Carlos (Centre de Recerca en Agrigenòmica) ;
Martín-Hernández, Ana Montserrat (Centre de Recerca en Agrigenòmica) ;
Pujol Abajo, Marta (Centre de Recerca en Agrigenòmica) ;
Garcia-Mas, Jordi (Centre de Recerca en Agrigenòmica)
Fruit ripening is an important process that affects fruit quality. A QTL in melon, ETHQV6. 3, involved in climacteric ripening regulation, has been found to be encoded by CmNAC-NOR, a homologue of the tomato NOR gene. [...]
2022 - 10.3389/fpls.2022.878037
Frontiers in plant science, Vol. 13 (June 2022) , art. 878037
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3.
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18 p, 5.2 MB |
Fruit morphology and ripening-related QTLs in a newly developed introgression line collection of the elite varieties 'Védrantais' and 'Piel de Sapo'
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Santo Domingo, Miguel (Centre de Recerca en Agrigenòmica) ;
Mayobre, Carlos (Centre de Recerca en Agrigenòmica) ;
Pereira, Lara (Centre de Recerca en Agrigenòmica) ;
Argyris, Jason (Centre de Recerca en Agrigenòmica) ;
Valverde, Laura (Centre de Recerca en Agrigenòmica) ;
Martín-Hernández, Ana Montserrat (Centre de Recerca en Agrigenòmica) ;
Garcia-Mas, Jordi (Centre de Recerca en Agrigenòmica) ;
Pujol Abajo, Marta (Centre de Recerca en Agrigenòmica)
Melon is an economically important crop with widely diverse fruit morphology and ripening characteristics. Its diploid sequenced genome and multiple genomic tools make this species suitable to study the genetic architecture of fruit traits. [...]
2022 - 10.3390/plants11223120
Plants, Vol. 11, issue 22 (Nov. 2022) , art. 3120
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4.
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13 p, 1.2 MB |
Modulating climacteric intensity in melon through QTL stacking
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Santo Domingo, Miguel (Centre de Recerca en Agrigenòmica) ;
Areco, Lorena (Centre de Recerca en Agrigenòmica) ;
Mayobre, Carlos (Centre de Recerca en Agrigenòmica) ;
Valverde, Laura (Centre de Recerca en Agrigenòmica) ;
Martín-Hernández, Ana Montserrat (Centre de Recerca en Agrigenòmica) ;
Pujol Abajo, Marta (Centre de Recerca en Agrigenòmica) ;
Garcia-Mas, Jordi (Centre de Recerca en Agrigenòmica)
Fruit ripening is one of the main processes affecting fruit quality and shelf life. In melon there are both climacteric and non-climacteric genotypes, making it a suitable species to study fruit ripening. [...]
2022 - 10.1093/hr/uhac131
Horticulture research, Vol. 9 (June 2022) , art. uhac131
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25 p, 23.2 MB |
CRISPR/Cas9 gene editing uncovers the roles of CONSTITUTIVE TRIPLE RESPONSE 1 and REPRESSOR OF SILENCING 1 in melon fruit ripening and epigenetic regulation
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Giordano, Andrea (Centre de Recerca en Agrigenòmica) ;
Santo Domingo, Miguel (Centre de Recerca en Agrigenòmica) ;
Quadrana, Leandro (Institut de Biologie de l'Ecole Normale Supérieure) ;
Pujol Abajo, Marta (Centre de Recerca en Agrigenòmica) ;
Martín-Hernández, Ana Montserrat (Centre de Recerca en Agrigenòmica) ;
Garcia-Mas, Jordi (Centre de Recerca en Agrigenòmica)
Melon (Cucumis melo) has emerged as an alternative model to tomato for studying fruit ripening due to the coexistence of climacteric and non-climacteric varieties. Previous characterization of a major quantitative trait locus (QTL), ETHQV8. [...]
2022 - 10.1093/jxb/erac148
Journal of Experimental Botany, Vol. 73, Issue 12 (June 2022) , p. 4022-4033
2 documents
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6.
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18 p, 7.7 MB |
Genetic dissection of climacteric fruit ripening in a melon population segregating for ripening behavior
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Pereira, Lara (Centre de Recerca en Agrigenòmica) ;
Santo Domingo, Miguel (Centre de Recerca en Agrigenòmica) ;
Ruggieri, Valentino (Centre de Recerca en Agrigenòmica) ;
Argyris, Jason (Centre de Recerca en Agrigenòmica) ;
Phillips, Michael A. (University of Toronto. Department of Biology) ;
Zhao, Guangwei (Zhengzhou Fruit Research Institute) ;
Lian, Qun (Agricultural Genomics Institute at Shenzhen) ;
Xu, Yongyang (Zhengzhou Fruit Research Institute) ;
He, Yuhua (Zhengzhou Fruit Research Institute) ;
Huang, Sanwen (Agricultural Genomics Institute at Shenzhen) ;
Pujol Abajo, Marta (Centre de Recerca en Agrigenòmica) ;
Garcia-Mas, Jordi (Centre de Recerca en Agrigenòmica)
Melon is as an alternative model to understand fruit ripening due to the coexistence of climacteric and non-climacteric varieties within the same species, allowing the study of the processes that regulate this complex trait with genetic approaches. [...]
2020 - 10.1038/s41438-020-00411-z
Horticulture research, Vol. 7 (November 2020) , art. 187
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7.
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13 p, 4.7 MB |
A novel introgression line collection to unravel the genetics of climacteric ripening and fruit quality in melon
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Pereira, Lara (Centre de Recerca en Agrigenòmica) ;
Santo Domingo, Miguel (Centre de Recerca en Agrigenòmica) ;
Argyris, Jason (Centre de Recerca en Agrigenòmica) ;
Mayobre, Carlos (Centre de Recerca en Agrigenòmica) ;
Valverde, Laura (Centre de Recerca en Agrigenòmica) ;
Martín-Hernández, Ana Montserrat (Centre de Recerca en Agrigenòmica) ;
Pujol Abajo, Marta (Centre de Recerca en Agrigenòmica) ;
Garcia-Mas, Jordi (Centre de Recerca en Agrigenòmica)
Introgression lines are valuable germplasm for scientists and breeders, since they ease genetic studies such as QTL interactions and positional cloning as well as the introduction of favorable alleles into elite varieties. [...]
2021 - 10.1038/s41598-021-90783-6
Scientific reports, Vol. 11 (May 2021) , art 11364
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8.
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11 p, 1.8 MB |
A Complementary Scale of Biased Agonism for Agonists with Differing Maximal Responses
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Burgueño, Javier (Department of Pharmacology, Drug Discovery & Preclinical Development, ESTEVE) ;
Pujol Argemí, Marta (Department of Pharmacology, Drug Discovery & Preclinical Development, ESTEVE) ;
Monroy, Xavier (Department of Pharmacology, Drug Discovery & Preclinical Development, ESTEVE) ;
Roche, David (Universitat Internacional de Catalunya. Facultat de Ciències Econòmiques i Socials) ;
Varela, Maria Jose (Universidade de Santiago de Compostela) ;
Merlos, Manuel (Department of Pharmacology, Drug Discovery & Preclinical Development, ESTEVE) ;
Giraldo, Jesús (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Universitat Autònoma de Barcelona.
Departament de Pediatria, Obstetrícia i Ginecologia i de Medicina Preventiva i Salut Pública
Compelling data in the literature from the recent years leave no doubt about the pluridimensional nature of G protein-coupled receptor function and the fact that some ligands can couple with different efficacies to the multiple pathways that a receptor can signal through, a phenomenon most commonly known as functional selectivity or biased agonism. [...]
2017 - 10.1038/s41598-017-15258-z
Scientific reports, Vol. 7 (november 2017)
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9.
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43 p, 1.5 MB |
Genetic dissection of aroma biosynthesis in melon and its relationship with climacteric ripening
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Mayobre, Carlos (Centre de Recerca en Agrigenòmica) ;
Pereira, Lara (Centre de Recerca en Agrigenòmica) ;
Eltahiri, Abdelali (Centre de Recerca en Agrigenòmica) ;
Bar, Einat (Newe Ya'ar Research Center) ;
Lewinsohn, Efraim (Newe Ya'ar Research Center) ;
Garcia-Mas, Jordi (Centre de Recerca en Agrigenòmica) ;
Pujol Abajo, Marta (Centre de Recerca en Agrigenòmica)
Aroma is an essential trait in melon fruit quality, but its complexity and genetic basis are still poorly understood. The aim of this study was the identification of quantitative trait loci (QTLs) underlying volatile organic compounds (VOCs) biosynthesis in melon rind and flesh, using a Recombinant Inbred Line (RIL) population from the cross 'Piel de Sapo' (PS) × 'Védrantais' (VED), two commercial varieties segregating for ripening behavior. [...]
2021 - 10.1016/j.foodchem.2021.129484
Food chemistry, Vol. 353 (August 2021) , art. 129484
3 documents
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10.
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10 p, 860.7 KB |
GENOMES UNCOUPLED1-independent retrograde signaling targets the ethylene pathway to repress photomorphogenesis
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Gommers, Charlotte M. M. (Centre de Recerca en Agrigenòmica) ;
Ruiz-Sola, M. Águila (Centre de Recerca en Agrigenòmica) ;
Ayats, Alba (Centre de Recerca en Agrigenòmica) ;
Pereira, Lara (Centre de Recerca en Agrigenòmica) ;
Pujol Abajo, Marta (Centre de Recerca en Agrigenòmica) ;
Monte Collado, Elena (Centre de Recerca en Agrigenòmica)
When germinating in the light, Arabidopsis (Arabidopsis thaliana) seedlings undergo photomorphogenic development, characterized by short hypocotyls, greening, and expanded cotyledons. Stressed chloroplasts emit retrograde signals to the nucleus that induce developmental responses and repress photomorphogenesis. [...]
2021 - 10.1093/plphys/kiaa015
Plant Physiology, Vol. 185, Issue 1 (January 2021) , p. 67-76
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