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10 p, 774.9 KB |
The impact of improving haemophilia A management within the Spanish National Healthcare System : a social return on investment analysis
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Soto, Inmaculada (Hospital Universitario Central de Asturias) ;
Mateo, José (Institut d'Investigació Biomèdica Sant Pau) ;
García-Diego, Daniel Aníbal (Federación Española de Hemofilia - FEDHEMO) ;
Gil, Beatriz (Roche Farma España) ;
Ruiz-Beato, Elena (Roche Farma España) ;
Ivanova, Yoana (Weber) ;
Martín Lorenzo, Teresa (Weber) ;
Maravilla-Herrera, Paulina (Weber) ;
Hidalgo-Vega, Álvaro (Universidad de Castilla-La Mancha) ;
Merino, María (Weber) ;
Universitat Autònoma de Barcelona
Haemophilia A (HA) has been associated with poor health-related quality of life and a large economic burden, accentuated by severity, arthropathy, and inhibitors. To meet global standards of care, the management of HA should align with the principles of care outlined by the World Federation of Haemophilia. [...]
2022 -  10.1186/s12913-021-07447-4
BMC health services research, Vol. 22 Núm. 1 (december 2022) , p. 115
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11 p, 2.6 MB |
Detection of kinase domain mutations in BCR::ABL1 leukemia by ultra-deep sequencing of genomic DNA
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Sánchez, Ricardo (Hospital Universitario 12 de Octubre (Madrid)) ;
Dorado, Sara (Universidad Carlos III de Madrid. Departamento de Informática e Ingeniería) ;
Ruíz-Heredia, Yanira (Altum Sequencing (Madrid)) ;
Martín-Muñoz, Alejandro (Altum Sequencing (Madrid)) ;
Rosa-Rosa, J.M. (Unidad de Investigación Clínica de Neoplasias Hematológicas (Madrid)) ;
Ribera Salas, Jordi (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
García, Olga (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Jimenez-Ubieto, Ana (Unidad de Investigación Clínica de Neoplasias Hematológicas (Madrid)) ;
Carreño-Tarragona, Gonzalo (Unidad de Investigación Clínica de Neoplasias Hematológicas (Madrid)) ;
Linares, Maria (Universidad Complutense de Madrid. Departamento de Bioquímica y Biología Molecular) ;
Rufián, Laura (Altum Sequencing (Madrid)) ;
Juárez, Alexandra (Altum Sequencing (Madrid)) ;
Carrillo García, Jaime (Altum Sequencing (Madrid)) ;
Espino, María José (Hospital Universitario 12 de Octubre (Madrid)) ;
Cáceres, Mercedes (Hospital Universitario 12 de Octubre (Madrid)) ;
Expósito, Sara (Instituto Cajal (Consejo Superior de Investigaciones Científicas)) ;
Cuevas, Beatriz (Hospital Universitario de Burgos) ;
Vanegas, Raúl (Hospital General Universitario de Ciudad Real) ;
Casado Montero, Luis Felipe (Hospital Virgen de la Salud (Toledo)) ;
Torrent Catarineu, Anna (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Zamora, Lurdes (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Mercadal, Santiago (Hospital Duran i Reynals (Barcelona)) ;
Coll, Rosa (Hospital Universitari de Girona Doctor Josep Trueta) ;
Cervera, Marta (Hospital Universitari Joan XXIII de Tarragona) ;
Morgades, Mireia (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Hernández-Rivas, José Angel (Hospital Universitario Infanta Leonor) ;
Bravo, Pilar (Hospital Universitario de Fuenlabrada ( Madrid)) ;
Serí, Cristina (Hospital Central de la Defensa Gómez Ulla) ;
Anguita, Eduardo (Hospital Clínico San Carlos (Madrid)) ;
Barragán, Eva (Hospital Universitari i Politècnic La Fe (València)) ;
Sargas, Claudia (Hospital Universitari i Politècnic La Fe (València)) ;
Ferrer-Marín, Francisco (Hospital General Universitario Morales Meseguer (Múrcia)) ;
Sánchez-Calero, Jorge (Hospital Universitario de Móstoles (Madrid)) ;
Sevilla, Julián (Hospital Infantil Universitario Niño Jesús (Madrid)) ;
Ruíz, Elena (Hospital del Tajo) ;
Villalón, Lucía (Hospital Universitario Fundación Alcorcón) ;
Herráez, María del Mar (Hospital Santa Bárbara) ;
Riaza, Rosalía (Hospital Universitario Severo Ochoa) ;
Magro, Elena (Hospital Universitario Príncipe de Asturias (Alcalá de Henares, Madrid)) ;
Steegman, Juan Luís (Hospital Universitario de la Princesa (Madrid)) ;
Wang, Chongwu (Hosea Precision Medical Technology (Xina)) ;
de Toledo, Paula (Universidad Carlos III de Madrid. Departamento de Informática e Ingeniería) ;
García-Gutiérrez, Valentín (Instituto Ramón y Cajal de Investigación Sanitaria (Madrid)) ;
Ayala, Rosa (Centro de Investigación Biomédica en Red de Cáncer) ;
Ribera, Jose-Maria (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Barrio, Santiago (Altum Sequencing (Madrid)) ;
Martínez-López, Joaquín (Centro de Investigación Biomédica en Red de Cáncer) ;
Universitat Autònoma de Barcelona
The screening of the BCR::ABL1 kinase domain (KD) mutation has become a routine analysis in case of warning/failure for chronic myeloid leukemia (CML) and B-cell precursor acute lymphoblastic leukemia (ALL) Philadelphia (Ph)-positive patients. [...]
2022 - 10.1038/s41598-022-17271-3
Scientific reports, Vol. 12 Núm. 1 (december 2022) , p. 13057
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11 p, 2.6 MB |
Historic exposure to herbivores, not constitutive traits, explains plant tolerance to herbivory in the case of two Medicago species (Fabaceae)
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Capo, Miquel (Universitat de les Illes Balears. Departament de Biologia) ;
Roig-Oliver, M. (Universitat de les Illes Balears. Departament de Biologia) ;
Cardona, C. (Centre Forestal de les Illes Balears. Institut Balear de la Natura) ;
Cursach, J. (Universitat de les Illes Balears. Departament de Biologia) ;
Bartolomé, Jordi (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ;
Rita, J. (Universitat de les Illes Balears. Departament de Biologia) ;
Baraza Ruíz, Elena (Universitat de les Illes Balears. Departament de Biologia)
Mechanisms that allow plants to survive and reproduce after herbivory are considered to play a key role in plant evolution. In this study, we evaluated how tolerance varies in species with different historic exposure to herbivores considering ontogeny. [...]
2021 - 10.1016/j.plantsci.2021.110890
Plant science, Vol. 307 (june 2021) , p. 110890
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18 p, 4.1 MB |
Satellite-based monitoring of primary production in a mediterranean islet post black rat eradication
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Ibañez-Álvarez, Miguel (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ;
Santasusana, Pol (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Calleja, Juan Antonio (Universidad Autónoma de Madrid. Centro de Investigación en Biodiversidad y Cambio Global) ;
Rouco, Carlos (Universidad de Córdoba. Departamento de Botánica, Ecología y Fisiología Vegetal) ;
Brolly, Matthew (University of Brighton. Centre for Earth Observation Sciences) ;
Burnside, Niall (University of Brighton. Centre for Earth Observation Sciences) ;
Baraza Ruíz, Elena (Universitat de les Illes Balears. Departament de Biologia) ;
Bartolomé, Jordi (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ;
Serrano Ferron, Emmanuel (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
Invasive rodents have a detrimental impact on terrestrial ecosystem functioning, this is often exacerbated on small islands. Rat eradication campaigns are often used to deal with this environmental perturbation given their classification as invasive species. [...]
2022 - 10.3390/rs14010101
Remote sensing (Basel), Vol. 14 Núm. 1 (1-1 2022) , p. 101
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9 p, 290.0 KB |
GERD after Bariatric Surgery. Can We Expect Endoscopic Findings?
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Vilallonga, Ramon (Clinique Saint Michel) ;
Sanchez-Cordero, Sergi (Hospital d'Igualada) ;
Umpiérrez Mayor, Nicolas (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Molina, Alicia (Clínica Corachan (Barcelona, Catalunya)) ;
Cirera de Tudela, Arturo (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ruiz-Úcar, Elena (Hospital Universitario de Fuenlabrada ( Madrid)) ;
Carrasco, Manel Armengol (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
Background and Objectives : Bariatric surgery remains the gold standard treatment for morbidly obese patients. Roux-en-y gastric bypass and laparoscopic sleeve gastrectomy are the most frequently performed surgeries worldwide. [...]
2021 - 10.3390/medicina57050506
Medicina, Vol. 57 (may 2021)
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16 p, 2.4 MB |
TYK2 Variants in B-Acute Lymphoblastic Leukaemia
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Turrubiartes-Martínez, Edgar (Instituto de Investigación Hospital Universitario de la Princesa) ;
Bodega-Mayor, Irene (Instituto de Investigación Hospital Universitario de la Princesa) ;
Delgado-Wicke, Pablo (Instituto de Investigación Hospital Universitario de la Princesa) ;
Molina-Jiménez, Francisca (Instituto de Investigación Hospital Universitario de la Princesa) ;
Casique-Aguirre, Diana (Latin University of Mexico) ;
González-Andrade, Martín (Universidad Nacional Autónoma de México) ;
Rapado, Inmaculada (Instituto de Investigación Sanitaria Hospital 12 de Octubre (i+12)) ;
Camós, Mireia (University Hospital Sant Joan de Déu) ;
Díaz de Heredia, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Barragán, Eva (Hospital Universitari i Politècnic La Fe (València)) ;
Ramírez, Manuel (Hospital Infantil Universitario Niño Jesús (Madrid)) ;
Aguado, Beatriz (Instituto de Investigación Hospital Universitario de la Princesa) ;
Figuera, Ángela (Instituto de Investigación Hospital Universitario de la Princesa) ;
Martínez-López, Joaquín (Complutense University of Madrid) ;
Fernández-Ruiz, Elena (Universidad Autónoma de Madrid) ;
Universitat Autònoma de Barcelona
B-cell precursor acute lymphoblastic leukaemia (B-ALL) is a malignancy of lymphoid progenitor cells with altered genes including the Janus kinase (JAK) gene family. Among them, tyrosine kinase 2 (TYK2) is involved in signal transduction of cytokines such as interferon (IFN) α/β through IFN−α/β receptor alpha chain (IFNAR1). [...]
2020 - 10.3390/genes11121434
Genes, Vol. 11 (november 2020)
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10 p, 2.3 MB |
Burden and attitude to resistant and refractory migraine : a survey from the European Headache Federation with the endorsement of the European Migraine & Headache Alliance
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Sacco, Simona (ASL Avezzano-Sulmona-L'Aquila) ;
Lampl, Christian (Hospital Barmherzige Brüder) ;
Maassen van den Brink, Antoinette (Erasmus MC University Medical Center Rotterdam) ;
Caponnetto, Valeria (ASL Avezzano-Sulmona-L'Aquila) ;
Ducros, Anne (University Hospital of Montpellier (França)) ;
Little, Patrick (European Migraine & Headache Alliance (EMHA), Brussels) ;
Pozo-Rosich, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Reuter, Uwe (Charité - Universitätsmedizin Berlin) ;
Ruiz de la Torre, Elena (European Migraine & Headache Alliance (EMHA), Brussels) ;
Sánchez Del Rio, Margarita (Clínica Universidad de Navarra) ;
Sinclair, Alexandra J. (Birmingham Health Partners) ;
Martelletti, Paolo (Sant'Andrea Hospital) ;
Katsarava, Zaza (IM Sechenov First Moscow State Medical University) ;
Universitat Autònoma de Barcelona
New treatments are currently offering new opportunities and challenges in clinical management and research in the migraine field. There is the need of homogenous criteria to identify candidates for treatment escalation as well as of reliable criteria to identify refractoriness to treatment. [...]
2021 - 10.1186/s10194-021-01252-4
Journal of headache and pain, Vol. 22 (may 2021)
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14 p, 8.4 MB |
The Role of Feral Goats in Maintaining Firebreaks by Using Attractants
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Pareja Loayza, Javier Ciprian (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ;
Ibañez-Álvarez, Miguel (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ;
Domenech, Oriol (Govern d'Illes Balears. Ministeri d'Entorn i Territori) ;
Bartolomé, Jordi (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ;
Baraza Ruíz, Elena (Universitat de les Illes Balears. Departament de Biologia)
The threat of large forest fires is increasing, and the main causes are the depopulation of rural areas, along with the effects of climate change. To counter this threat in recent decades, there have been numerous proposals and actions aimed at promoting grazing in the forest as a tool for controlling biomass fuel. [...]
2020 - 10.3390/su12177144
Sustainability, Vol. 12 Núm. 17 (2020) , p. 7144
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9 p, 1.4 MB |
Preference by Donkeys and Goats among Five Mediterranean Forest Species : Implications for Reducing Fire Hazard
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Bartolomé, Jordi (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ;
Broncano Atencia, María José (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ;
Plaixats i Boixadera, Josefina (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ;
Rigau, Teresa (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Milán Sendra, María José (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ;
Baraza Ruíz, Elena (Universitat de les Illes Balears. Departament de Biologia) ;
Miró, Jordi (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Panadès, Xavier (Museu de la Conca Dellà (Isona, Catalunya))
During the second half of the 20th century, European countries experienced an increase in their forest area due to the global change. Consequently, there has been an increase in large forest fires, mainly in the Mediterranean basin, and this has forced the development of several types of prevention programs. [...]
2020 - 10.3390/ani10081302
Animals, Vol. 10 Núm. 8 (2020) , p. 1302
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