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28 p, 1.7 MB |
Una ontología híbrida de género : cromosomas, fotografías y ecografías en la circulación de la imaginería fetal en España, 1950-1970
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Santesmases, María Jesús (Consejo Superior de Investigaciones Científicas (Espanya). Instituto de Filosofía)
Este texto presenta una propuesta de cronología de imágenes fetales en España, que incluye el proceso de producción y circulación de representaciones de cromosomas humanos -el cariotipo como retrato-, de las fotografías hechas y publicadas por el fotógrafo sueco Lennart Nilsson y de las figuras obtenidas por ecografía. [...]
This article presents a proposal for a chronology of fetal images in Spain that includes the process of production and circulation of human chromosomes (fetal karyotype as a portrait), of the photographs of fetuses by Lennart Nilsson, and of the images provided by ultrasound scanning. [...]
2023
Dynamis : Acta Hispanica ad Medicinae Scientiarumque. Historiam Illustrandam, Vol. 43 Núm. 2 (2023) , p. 459-485 (Dossier)
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18 p, 851.1 KB |
Clinical outcome measures in dementia with Lewy bodies trials : critique and recommendations
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Rodriguez-Porcel, Federico (Medical University of South Carolina) ;
Wyman-Chick, Kathryn A. (HealthPartners) ;
Abdelnour, Carla (Universitat Autònoma de Barcelona) ;
Toledo, Jon B. (University of Florida) ;
Ferreira, Daniel (Mayo Clinic) ;
Urwyler, Prabitha (University of Bern) ;
Weil, Rimona S. (University College London) ;
Kane, Joseph (Queen's University) ;
Pilotto, Andrea (University of Brescia) ;
Rongve, Arvid (The University of Bergen) ;
Boeve, Bradley (Mayo Clinic) ;
Taylor, John-Paul (Newcastle University) ;
McKeith, Ian (Newcastle University) ;
Aarsland, Dag (King's College London) ;
Lewis, Simon J. G. (University of Sydney)
The selection of appropriate outcome measures is fundamental to the design of any successful clinical trial. Although dementia with Lewy bodies (DLB) is one of the most common neurodegenerative conditions, assessment of therapeutic benefit in clinical trials often relies on tools developed for other conditions, such as Alzheimer's or Parkinson's disease. [...]
2022 -  10.1186/s40035-022-00299-w
Translational Neurodegeneration, Vol. 11 (may 2022)
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1 p, 574.4 KB |
Correction : Clinical outcome measures in dementia with Lewy bodies trials: critique and recommendations
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Rodriguez-Porcel, Federico (Medical University of South Carolina) ;
Wyman-Chick, Kathryn A. (HealthPartners) ;
Abdelnour, Carla (Universitat Autònoma de Barcelona) ;
Toledo, Jon B. (University of Florida) ;
Ferreira, Daniel (Mayo Clinic) ;
Urwyler, Prabitha (University of Bern) ;
Weil, Rimona S. (University College London) ;
Kane, Joseph (Queen's University) ;
Pilotto, Andrea (University of Brescia) ;
Rongve, Arvid (The University of Bergen) ;
Boeve, Bradley (Mayo Clinic) ;
Taylor, John-Paul (Newcastle University) ;
McKeith, Ian (Newcastle University) ;
Aarsland, Dag (King's College London) ;
Lewis, Simon J. G. (University of Sydney)
The selection of appropriate outcome measures is fundamental to the design of any successful clinical trial. Although dementia with Lewy bodies (DLB) is one of the most common neurodegenerative conditions, assessment of therapeutic benefit in clinical trials often relies on tools developed for other conditions, such as Alzheimer's or Parkinson's disease. [...]
2022 - 10.1186/s40035-022-00306-0
Translational Neurodegeneration, Vol. 11 (may 2022)
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22 p, 3.7 MB |
A 3D deep learning model to predict the diagnosis of dementia with Lewy bodies, Alzheimer's disease, and mild cognitive impairment using brain 18F-FDG PET
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Etminani, Kobra (Center for Applied Intelligent Systems Research (CAISR). Halmstad University) ;
Soliman, Amira (Center for Applied Intelligent Systems Research (CAISR). Halmstad University) ;
Davidsson, Anette (Department of Clinical Physiology. Department of Health. Medicine and Caring Sciences. Linköping University) ;
Chang, Jose R. (National Cheng Kung University in Tainan) ;
Martínez-Sanchis, Begoña (Hospital Universitari i Politècnic La Fe (València)) ;
Byttner, Stefan (Center for Applied Intelligent Systems Research (CAISR). Halmstad University) ;
Camacho, Valle (Institut d'Investigació Biomèdica Sant Pau) ;
Bauckneht, Matteo (Nuclear Medicine Unit. IRCCS Ospedale Policlinico San Martino) ;
Stegeran, Roxana (Department of Diagnostic Radiology. Linköping University Hospital) ;
Ressner, Marcus (Department of Medical Physics. Linköping University Hospital) ;
Agudelo-Cifuentes, Marc (Hospital Universitari i Politècnic La Fe (València)) ;
Chincarini, Andrea (National Institute of Nuclear Physics (INFN)) ;
Brendel, Matthias (Department of Nuclear Medicine. University Hospital. LMU Munich) ;
Rominger, Axel (Department of Nuclear Medicine. Inselspital. University Hospital Bern) ;
Bruffaerts, Rose (Biomedical Research Institute. Hasselt University) ;
Vandenberghe, Rik (Neurology Department. University Hospitals Leuven) ;
Kramberger, Milica G. (Department of Neurology. University Medical Centre) ;
Trost, Maja (Univerza V Ljubljani) ;
Nicastro, Nicolas (Department of Clinical Neurosciences. Geneva University Hospitals) ;
Frisoni, Giovanni B. (LANVIE (Laboratoire de Neuroimagerie du Vieillissement). Department of Psychiatry. University Hospitals) ;
Lemstra, Afina W. (Department of Neurology. Alzheimer Center) ;
van Berckel, Bart N.M. (Department of Radiology & Nuclear Medicine. Amsterdam UMC. location VUmc) ;
Pilotto, Andrea (Parkinson's Disease Rehabilitation Centre) ;
Padovani, Alessandro (Neurology Unit. Department of Clinical and Experimental Sciences. University of Brescia) ;
Morbelli, Silvia (Department of Health Sciences. University of Genoa) ;
Aarsland, Dag (Department of Old Age Psychiatry. Institute of Psychiatry. Psychology and Neuroscience. King's College London) ;
Nobili, Flavio (Clinical Neurology. IRCCS Ospedale Policlinico San Martino) ;
Garibotto, Valentina (Division of Nuclear Medicine and Molecular Imaging. University Hospitals of Geneva and NIMTLab. Faculty of Medicine. University of Geneva) ;
Ochoa-Figueroa, Miguel (Center for Medical Image Science and Visualization (CMIV). Linköping University) ;
Universitat Autònoma de Barcelona
Purpose: The purpose of this study is to develop and validate a 3D deep learning model that predicts the final clinical diagnosis of Alzheimer's disease (AD), dementia with Lewy bodies (DLB), mild cognitive impairment due to Alzheimer's disease (MCI-AD), and cognitively normal (CN) using fluorine 18 fluorodeoxyglucose PET (18F-FDG PET) and compare model's performance to that of multiple expert nuclear medicine physicians' readers. [...]
2022 - 10.1007/s00259-021-05483-0
European Journal of Nuclear Medicine and Molecular Imaging, Vol. 49 Núm. 2 (january 2022) , p. 563-584
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12 p, 391.9 KB |
Autoras marginales y subjetividades excéntricas en los espacios de la ciencia ficción sudamericana escrita por mujeres
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Cortés Correa, Macarena (Universitat Autònoma de Barcelona)
La ciencia ficción escrita por mujeres en Latinoamérica ha permanecido en los bordes del campo literario por su condición de triple marginalidad, debido a la apreciación de la ciencia ficción como un género menor respecto a aquellos canónicos promovidos desde la institucionalidad literaria, a la invisibilidad de la escritura de las mujeres en los medios literarios, y a la posición de América Latina como "Tercer Mundo" respecto a los países desarrollados. [...]
La ciència-ficció escrita per dones a Llatinoamèrica ha romàs en les vores del camp literari per la seva condició de triple marginalitat, a causa de l'apreciació de la ciència-ficció com un gènere menor respecte a aquells canònics promoguts des de la institucionalitat literària, a la invisibilitat de l'escriptura de les dones en els mitjans literaris, i a la posició d'Amèrica Llatina com a "Tercer Món" respecte als països desenvolupats. [...]
Science fiction written by Latin American women has remained at the edges of the literary field because of its status as a triple marginality, due to the appreciation of science fiction as a minor genre compared to those canonical promoted from the literary institutions, the invisibility of women's writing in literary media, and due to the position of Latin America as a "Third World" in relation to the hegemonic discourse. [...]
2022 - 10.5565/rev/mitologias.887
Mitologías hoy, Vol. 26 (2022) , p. 21-32 (Dossier)
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11 p, 2.5 MB |
The small aromatic compound SynuClean-D inhibits the aggregation and seeded polymerization of multiple α-synuclein strains
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Peña Díaz, Samuel (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Pujols Pujol, Jordi (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Vasili, Eftychia (Max Planck Institute for Experimental Medicine) ;
Pinheiro, Francisca (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Santos, Jaime (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Manglano-Artuñedo, Zoe (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Outeiro, Tiago Fleming (Scientific Employee With a Honorary Contract. Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE)) ;
Ventura, Salvador (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
Parkinson's disease is a neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra, as well as the accumulation of intraneuronal proteinaceous inclusions known as Lewy bodies and Lewy neurites. [...]
2022 - 10.1016/j.jbc.2022.101902
Journal of biological chemistry, Vol. 298, Issue 5 (May 2022) , art. 101902
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