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Resultats globals: 7 registres trobats en 0.03 segons.
Articles, 6 registres trobats
Documents de recerca, 1 registres trobats
Articles 6 registres trobats  
1.
30 p, 1.3 MB SSAO/VAP-1 in Cerebrovascular Disorders : A Potential Therapeutic Target for Stroke and Alzheimer's Disease / Unzeta López, Mercedes (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Hernandez Guillamon, Maria Mar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Sun, Ping (University of Pittsburgh School of Medicine) ; Solé Piñol, Montserrat (Hospital Universitari Vall d'Hebron. Institut de Recerca)
The semicarbazide-sensitive amine oxidase (SSAO), also known as vascular adhesion protein-1 (VAP-1) or primary amine oxidase (PrAO), is a deaminating enzyme highly expressed in vessels that generates harmful products as a result of its enzymatic activity. [...]
2021 - 10.3390/ijms22073365
International journal of molecular sciences, Vol. 22 (march 2021)  
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2.
30 p, 861.2 KB Relevance of Porcine Stroke Models to Bridge the Gap from Pre-Clinical Findings to Clinical Implementation / Melià Sorolla, Marc (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; De Gregorio-Rocasolano, Nuria (Institut Germans Trias i Pujol) ; Rodríguez-Esparragoza, Luis (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Dávalos, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martí-Sistac, Octavi (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Gasull Dalmau, Teresa (Institut Germans Trias i Pujol) ; Castaño Duque, Carlos (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
In the search of animal stroke models providing translational advantages for biomedical research, pigs are large mammals with interesting brain characteristics and wide social acceptance. Compared to rodents, pigs have human-like highly gyrencephalic brains. [...]
2020 - 10.3390/ijms21186568
International journal of molecular sciences, Vol. 21 Núm. 18 (2020) , p. 6568  
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3.
12 p, 1.3 MB Early measurement of interleukin-10 predicts the absence of CT scan lesions in mild traumatic brain injury / Lagerstedt, Linnéa (University of Geneva. Department of Human Protein Sciences) ; Egea Guerrero, Juan José (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Rodríguez Rodríguez, Ana (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Bustamante, Alejandro (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Montaner, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; El Rahal, Amir (Geneva University Hospitals (Suïssa)) ; Andereggen, Elisabeth (Geneva University Hospitals (Suïssa)) ; Rinaldi, Lara (Geneva University Hospitals (Suïssa)) ; Sarrafzadeh, Asita (Geneva University Hospitals (Suïssa)) ; Schaller, Karl (Geneva University Hospitals (Suïssa)) ; Sanchez, Jean-Charles (University of Geneva. Department of Human Protein Sciences)
Traumatic brain injury is a common event where 70%-90% will be classified as mild TBI (mTBI). Among these, only 10% will have a brain lesion visible via CT scan. A triage biomarker would help clinicians to identify patients with mTBI who are at risk of developing a brain lesion and require a CT scan. [...]
2019 - 10.1371/journal.pone.0193278
PloS one, Vol. 13 Núm. 2 (2019) , p. e0193278  
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4.
13 p, 3.4 MB Combining H-FABP and GFAP increases the capacity to differentiate between CT-positive and CT-negative patients with mild traumatic brain injury / Lagerstedt, Linnéa (University of Geneva. Department of Specialities of Internal Medicine) ; Egea Guerrero, Juan José (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Bustamante, Alejandro (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Rodríguez Rodríguez, Ana (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Quintana, Manuel (Hospital Universitario La Paz (Madrid)) ; García Armengol, Roser (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Prica, Carmen Melinda (Hospital de Tortosa Verge de la Cinta) ; Andereggen, Elisabeth (Geneva University Hospitals (Suïssa)) ; Rinaldi, Lara (Geneva University Hospitals (Suïssa)) ; Sarrafzadeh, Asita (Geneva University Hospitals (Suïssa)) ; Schaller, Karl (Geneva University Hospitals (Suïssa)) ; Montaner, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Sanchez, Jean-Charles (University of Geneva. Department of Specialities of Internal Medicine)
Mild traumatic brain injury (mTBI) patients may have trauma-induced brain lesions detectable using CT scans. However, most patients will be CT-negative. There is thus a need for an additional tool to detect patients at risk. [...]
2017 - 10.1371/journal.pone.0200394
PloS one, Vol. 12 Núm. 9 (2017) , p. e0185072  
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5.
16 p, 2.3 MB Iron-loaded transferrin (Tf) is detrimental whereas iron-free Tf confers protection against brain ischemia by modifying blood Tf saturation and subsequent neuronal damage / Gregorio-Rocasolano Barbany, Núria de (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martí Sistac, Octavi (Universitat Autònoma de Barcelona) ; Ponce, Jovita (Institut Germans Trias i Pujol) ; Castelló Ruiz, María (Instituto de Investigación Sanitaria La Fe) ; Millán Torné, Mònica (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Guirao, Verónica (Institut Germans Trias i Pujol) ; García Yébenes, Isaac (Universidad Complutense de Madrid. Departamento de Farmacología) ; Salom, Juan B. (Instituto de Investigación Sanitaria La Fe) ; Ramos Cabrer, Pedro (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ; Alborch, Enrique (Instituto de Investigación Sanitaria La Fe) ; Lizasoain, Ignacio (Universidad Complutense de Madrid. Departamento de Farmacología) ; Castillo, José (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ; Dávalos, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Gasull Dalmau, Teresa (Institut Germans Trias i Pujol)
Despite transferrin being the main circulating carrier of iron in body fluids, and iron overload conditions being known to worsen stroke outcome through reactive oxygen species (ROS)-induced damage, the contribution of blood transferrin saturation (TSAT) to stroke brain damage is unknown. [...]
2018 - 10.1016/j.redox.2017.11.026
Redox biology, Vol. 15 (May 2018) , p. 143-158  
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6.
13 p, 5.3 MB Oxidative stress and proinflammatory cytokines contribute to demyelination and axonal damage in a cerebellar culture model of neuroinflammation / Di Penta, Alessandra (Universidad del País Vasco. Neurogenomiks) ; Moreno, Beatriz (Hospital Clínic i Provincial de Barcelona) ; Reix, Stéphanie (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Fernández Díez, Begoña (Hospital Clínic i Provincial de Barcelona) ; Villanueva, Maite (Hospital Clínic i Provincial de Barcelona) ; Errea, Oihana (Hospital Clínic i Provincial de Barcelona) ; Escala, Nagore (Hospital Clínic i Provincial de Barcelona) ; Vandenbroeck, Koen (IKERBASQUE (Bilbao, Espanya)) ; Comella i Carnicé, Joan Xavier, 1963- (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Villoslada, Pablo (Hospital Clínic i Provincial de Barcelona)
Background: Demyelination and axonal damage are critical processes in the pathogenesis of multiple sclerosis (MS). Oxidative stress and pro-inflammatory cytokines elicited by inflammation mediates tissue damage. [...]
2013 - 10.1371/journal.pone.0054722
PloS one, Vol. 8, Issue 2 (February 2013) , p. e54722  
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Documents de recerca 1 registres trobats  
1.
291 p, 4.5 MB Función cognitiva en adultos con daño cerebral adquirido en fase crónica : relación con la actividad física y el sedentarismo / Pérez López, Lidia ; Coll-Andreu, Margalida, dir. ; Peter Morris, Timothy, dir.
El dany cerebral adquirit (DCA), principalment els accidents cerebrovasculars (ACV) i el traumatisme cranioencefàlic (TCE), constitueix la primera causa de discapacitat en adults. Les seqüeles del DCA poden persistir anys després de la lesió (fase crònica), amb les conseqüències que això comporta per al sistema de salut i en l'àmbit personal, familiar, social i econòmic. [...]
El daño cerebral adquirido (DCA), principalmente los accidentes cerebrovasculares (ACV) y el traumatismo craneoencefálico (TCE), constituye la primera causa de discapacidad en adultos. Las secuelas del DCA pueden persistir años después de la lesión (fase crónica), con las consecuencias que ello conlleva para el sistema de salud y a nivel personal, familiar, social y económico. [...]
Acquired brain injury (ABI), mainly stroke and traumatic brain injury (TBI), is the leading cause of disability in adults. The sequelae of ABI can persist years after the injury (chronic phase), with subsequent burden for the health system and at personal, family, social and economic levels. [...]
2022  
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