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Resultats globals: 3 registres trobats en 0.03 segons.
Articles, 3 registres trobats
Articles 3 registres trobats  
1.
13 p, 4.7 MB Unraveling the cellular origin and clinical prognostic markers of infant B-cell acute lymphoblastic leukemia using genome-wide analysis / Agraz-Doblás, Antonio (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Bueno, Clara (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Rogers, R. B. (Department of Medicine. University of Cambridge. Cambridge Biomedical Campus) ; Roy, A. (Department of Paediatrics. University of Oxford) ; Schneider, P. (Princess Maxima Center for Pediatric Oncology) ; Bardini, Michela (Università degli Studi di Milano-Bicocca) ; Ballerini, Paola (Pediatric Hematology. A. Trousseau Hospital) ; Cazzaniga, Giovanni (Centro Ricerca Tettamanti. Department of Pediatrics. University of Milano Bicocca. Fondazione MBBM) ; Moreno, T. (Instituto de Biomedicina y Biotecnología de Cantabria. Universidad de Cantabria-CSIC) ; Revilla, C. (Instituto de Biomedicina y Biotecnología de Cantabria. Universidad de Cantabria-CSIC) ; Gut, Marta (Universitat Pompeu Fabra) ; Valsecchi, M. G. (Interfant Trial Data Center. University of Milano-Bicocca) ; Roberts, I. (MRC Molecular Haematology Unit. MRC Weatherall Institute of Molecular Medicine. University of Oxford) ; Pieters, R. (Princess Maxima Center for Pediatric Oncology) ; De Lorenzo, P. (Interfant Trial Data Center. University of Milano-Bicocca) ; Varela, Ignacio (Instituto de Biomedicina y Biotecnología de Cantabria. Universidad de Cantabria-CSIC) ; Menéndez Bujan, Pablo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Stam, R. W. (Princess Maxima Center for Pediatric Oncology) ; Universitat Autònoma de Barcelona
Bcell acute lymphoblastic leukemia is the commonest childhood cancer. In infants, B-cell acute lymphoblastic leukemia remains fatal, especially in patients with t(4;11), present in ~80% of cases. The pathogenesis of t(4;11)/KMT2A-AFF1 (MLL-AF4) infant B-cell acute lymphoblastic leukemia remains difficult to model, and the pathogenic contribution in cancer of the reciprocal fusions resulting from derivative translocated-chromosomes remains obscure. [...]
2019 - 10.3324/haematol.2018.206375
Haematologica, Vol. 104 Núm. 6 (2019) , p. 1176-1188  
Registre complet - Creative Commons
2.
16 p, 3.8 MB The tumor suppressor SirT2 regulates cell cycle progression and genome stability by modulating the mitotic deposition of H4K20 methylation / Serrano, Lourdes (Department of Genetics, the Human Genetics Institute of New Jersey. Rutgers University) ; Martínez-Redondo, Paloma (Institut d'Investigació Biomèdica de Bellvitge) ; Marazuela Duque, Anna (Institut d'Investigació Biomèdica de Bellvitge) ; Vazquez Prat, Berta Nieves (Department of Genetics, the Human Genetics Institute of New Jersey. Rutgers University) ; Dooley, Scott J. (Department of Genetics, the Human Genetics Institute of New Jersey. Rutgers University) ; Voigt, Philipp (Department of Biochemistry, New York University School of Medicine) ; Beck, David B. (Department of Biochemistry, New York University School of Medicine) ; Kane-Goldsmith, Noriko (Department of Genetics, the Human Genetics Institute of New Jersey. Rutgers University) ; Tong, Qiang (Children's Nutrition Research Center) ; Rabanal Prados, Rosa Ma. (Rosa Maria) (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ; Fondevila, Dolors (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ; Muñoz, Purificación (Institut d'Investigació Biomèdica de Bellvitge) ; Krüger, Marcus (Max Planck Institute for Heart and Lung Research. Department of Cardiac Development and Remodeling) ; Tischfield, Jay A. (Department of Genetics, the Human Genetics Institute of New Jersey. Rutgers University) ; Vaquero, Alejandro (Institut d'Investigació Biomèdica de Bellvitge)
The establishment of the epigenetic mark H4K20me1 (monomethylation of H4K20) by PR-Set7 during G2/M directly impacts S-phase progression and genome stability. However, the mechanisms involved in the regulation of this event are not well understood. [...]
2013 - 10.1101/gad.211342.112
Genes & Development, 2013  
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3.
24 p, 287.2 KB Radiobiology and Reproduction : What Can We Learn from Mammalian Females? / Ruiz-Herrera Moreno, Aurora (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; García, Francisca (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Garcia-Caldés, Montserrat (Montserrat) (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Ionizing radiation damages DNA and induces mutations as well as chromosomal reorganizations. Although radiotherapy increases survival among cancer patients, this treatment does not come without secondary effects, among which the most problematic is gonadal dysfunction, especially in women. [...]
2012 - 10.3390/genes3030521
Genes, Vol. 3 (2012) , p. 521-544  
Registre complet - Creative Commons

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