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1.
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12 p, 2.8 MB |
Are bioplastics safe? : Hazardous effects of polylactic acid (PLA) nanoplastics in Drosophila
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Alaraby, Mohamed (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Abass, Doaa (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Farre, Marinella (Institut de Diagnosi Ambiental i Estudis de l'Aigua) ;
Hernández Bonilla, Alba (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Marcos Dauder, Ricardo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
The expanded uses of bioplastics require understanding the potential health risks associated with their exposure. To address this issue, Drosophila melanogaster as a versatile terrestrial in vivo model was employed, and polylactic acid nanoplastics (PLA-NPLs), as a proxy for bioplastics, were tested as a material model. [...]
2024 -  10.1016/j.scitotenv.2024.170592
Science of the total environment, Vol. 919 (April 2024) , art. 170592
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2.
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14 p, 7.3 MB |
Alcohol-free synthesis, biological assessment, in vivo toxicological evaluation, and in silico analysis of novel silane quaternary ammonium compounds differing in structure and chain length as promising disinfectants
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Tagorti, Ghada (Akdeniz University. Department of Biology) ;
Yalçın, Burçin (Akdeniz University. Department of Biology) ;
Güneş, Merve (Akdeniz University. Department of Biology) ;
Burgazlı, Ayşen Yağmur (Akdeniz University. Department of Biology) ;
Kuruca, Tuğçe (Akdeniz University. Department of Chemistry) ;
Cihanoğlu, Neslihan (Akdeniz University. Department of Chemistry) ;
Akarsu, Esin (Akdeniz University. Department of Chemistry) ;
Kaya, Nuray (Akdeniz University. Department of Biology) ;
Marcos Dauder, Ricardo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Kaya, Bülent (Akdeniz University. Department of Biology)
Quaternary ammonium compounds (QACs) are commonly used as disinfectants for industrial, medical, and residential applications. However, adverse health outcomes have been reported. Therefore, biocompatible disinfectants must be developed to reduce these adverse effects. [...]
2024 - 10.1016/j.jhazmat.2024.133470
Journal of hazardous materials, Vol. 466 (March 2024) , art. 133470
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3.
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10 p, 5.0 MB |
Titanium-doped PET nanoplastics, from opaque milk bottle degradation, as a model of environmental true-to-life nanoplastics. Hazardous effects on Drosophila
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Alaraby, Mohamed (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Villacorta, Aliro (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Abass, Doaa (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Hernández, Alba (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Marcos Dauder, Ricardo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Micro and nanoplastics (MNPLs) are emergent environmental pollutants, resulting from the degradation of plastic waste, requiring urgent information on their potential risks to human health. To determine such risks, reliable true-to-life materials are essential. [...]
2024 - 10.1016/j.envpol.2023.122968
Environmental Pollution, Vol. 341 (January 2024) , art. 122968
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4.
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14 p, 1.1 MB |
Insights into the potential carcinogenicity of micro- and nano-plastics
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Domenech, Josefe (Finnish Institute of Occupational Health) ;
Annangi, Balasubramanyam (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Marcos Dauder, Ricardo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Hernández Bonilla, Alba (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Catalán Rodríguez, Julia (Universidad de Zaragoza. Departamento de Anatomía, Embriología y Genética Animal)
There is a growing concern regarding the potential health effects that continuous exposure to environmental micro- and nano-plastics (MNPLs) may cause on humans. Due to their persistent nature, MNPLs may accumulate in different organs and tissues and may induce in the long term the development of cancer. [...]
2023 - 10.1016/j.mrrev.2023.108453
Mutation research. Reviews in mutation research, Vol. 791 (January 2023) , art. 108453
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5.
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21 p, 2.7 MB |
Lung recovery from DNA damage induced by graphene oxide is dependent on size, dose and inflammation profile
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De Luna, Luis Augusto Visani (Manchester Academic Health Science Centre) ;
Loret, Thomas (University of Manchester. Nanomedicine Lab) ;
Fordham, Alexander (University of Manchester. Nanomedicine Lab) ;
Arshad, Atta (University of Manchester. Nanomedicine Lab) ;
Drummond, Matthew (University of Manchester. National Graphene Institute) ;
Dodd, Abbie (University of Manchester. National Graphene Institute) ;
Lozano, Neus (Institut Català de Nanociència i Nanotecnologia) ;
Kostarelos, Kostas (Institut Català de Nanociència i Nanotecnologia) ;
Bussy, Cyrill (University of Manchester. Nanomedicine Lab)
A key aspect of any new material safety assessment is the evaluation of their in vivo genotoxicity. Graphene oxide (GO) has been studied for many promising applications, but there are remaining concerns about its safety profile, especially after inhalation. [...]
2022 - 10.1186/s12989-022-00502-w
Particle and fibre toxicology, Vol. 19 (September 2022) , art. 62
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6.
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12 p, 2.8 MB |
Antagonistic in vivo interaction of polystyrene nanoplastics and silver compounds. A study using Drosophila
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Alaraby, Mohamed (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Abass, Doaa (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Villacorta, Aliro (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Hernández Bonilla, Alba (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Marcos Dauder, Ricardo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Since heavy metals and micro−/nanoplastics (MNPLs) can share common environmental niches, their potential interactions could modulate their hazard impacts. The current study was planned to evaluate the potential interactions between silver compounds (silver nanoparticles or silver nitrate) and two different sizes of polystyrene nanoplastics (PSNPLs) (PS-50 and PS-500 nm), administered via ingestion to Drosophila larvae. [...]
2022 - 10.1016/j.scitotenv.2022.156923
Science of the total environment, Vol. 842 (October 2022) , art. 156923
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7.
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12 p, 7.9 MB |
Nanoplastics are bioaccumulated in fish liver and muscle and cause DNA damage after a chronic exposure
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Brandts, Irene (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Cánovas, M. (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Tvarijonaviciute, Asta (Universidad de Murcia. Laboratorio Interdisciplinario de Análisis Clínicos Interlab) ;
Llorca, Marta (Institut de Diagnosi Ambiental i Estudis de l'Aigua) ;
Vega, A. (Institut de Diagnosi Ambiental i Estudis de l'Aigua) ;
Farré, M. (Institut de Diagnosi Ambiental i Estudis de l'Aigua) ;
Pastor Milán, Josep (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Roher Armentia, Nerea (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Teles, Mariana (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
The extent of the widespread, planetary contamination by plastic waste is difficult to fully capture. Nanoplastics (NPs) are currently in the center of research concerning plastic litter, both for the analytical challenges they pose and for their potential to provoke hazardous effects in organisms. [...]
2022 - 10.1016/j.envres.2022.113433
Environmental Research, Vol. 212, Part A (September 2022) , art. 113433
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8.
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9.
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21 p, 2.2 MB |
Hepato(Geno)toxicity assessment of nanoparticles in a HepG2 liver spheroid model
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Elje, Elisabeth (Norwegian Institute for Air Research. Department for Environmental Chemistry) ;
Mariussen, Espen (Norwegian Institute for Air Research. Department for Environmental Chemistry) ;
Moriones, Oscar Hernando (Institut Català de Nanociència i Nanotecnologia) ;
Bastús, Neus G. (Institut Català de Nanociència i Nanotecnologia) ;
Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia) ;
Kohl, Yvonne (Fraunhofer Institute for Biomedical Engineering IBMT) ;
Dusinska, Maria (Norwegian Institute for Air Research. Department for Environmental Chemistry)) ;
Rundén-Pran, Elise (Norwegian Institute for Air Research. Department for Environmental Chemistry)
(1) In compliance with the 3Rs policy to reduce, refine and replace animal experiments, the development of advanced in vitro models is needed for nanotoxicity assessment. Cells cultivated in 3D resemble organ structures better than 2D cultures. [...]
2020 - 10.3390/nano10030545
Nanomaterials, Vol. 10, issue 3 (March 2020) , art. E545
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10.
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12 p, 1.0 MB |
Effects of titanium dioxide nanoparticles on the Hprt gene mutations in V79 hamster cells
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Kazimirova, Alena (Slovak Medical University. Department of Biology) ;
El Yamani, Naouale (Norwegian Institute for Air Research. Department of Environmental Chemistry) ;
Rubio Lorente, Laura (Universidad Católica Madre y Maestra. Laboratorio de Nanobiología) ;
García-Rodríguez, Alba (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Barančoková, Magdalena (Slovak Medical University. Department of Biology) ;
Marcos Dauder, Ricardo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Dusinska, Maria (Norwegian Institute for Air Research. Department of Environmental Chemistry)
The genotoxicity of anatase/rutile TiO nanoparticles (TiO NPs, NM105 at 3, 15 and 75 µg/cm 2) was assessed with the mammalian in-vitro Hypoxanthine guanine phosphoribosyl transferase (Hprt) gene mutation test in Chinese hamster lung (V79) fibroblasts after 24 h exposure. [...]
2020 - 10.3390/nano10030465
Nanomaterials, Vol. 10, issue 3 (March 2020) , art. 465
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