Resultats globals: 4 registres trobats en 0.02 segons.
Articles, 4 registres trobats
Articles 4 registres trobats  
1.
23 p, 2.8 MB Identification of specific effect of chloride on the spectral properties and structural stability of multiple extracellular glutamic acid mutants of bacteriorhodopsin / Lazarova, Tzvetana (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Mlynarczyk, Krzysztof (University of Warsaw. Faculty of Chemistry) ; Querol Murillo, Enrique (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Tenchov, Boris (Medical University (Sofia, Bulgària). Department of Medical Physics and Biophysics) ; Filipek, Slawomir (University of Warsaw. Faculty of Chemistry) ; Padrós, Esteve (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
In the present work we combine spectroscopic, DSC and computational approaches to examine the multiple extracellular Glu mutants E204Q/E194Q, E204Q/E194Q/E9Q and E204Q/E194Q/E9Q/E74Q of bacteriorhodopsin by varying solvent ionic strength and composition. [...]
2016 - 10.1371/journal.pone.0162952
PloS one, Vol. 11 issue 9 (2016) , art. e0162952  
2.
11 p, 2.7 MB Unveiled electric profiles within hydrogen bonds suggest DNA base pairs with similar bond strengths / Ruiz Blanco, Yasser B. (Universidad Central Marta Abreu de Las Villas) ; Almeida, Y. (University of Hamburg) ; Sotomayor Torres, Clivia M. (Institut Català de Nanociència i Nanotecnologia) ; García, Yamila (Universitat Politècnica de Catalunya)
Electrical forces are the background of all the interactions occurring in biochemical systems. From here and by using a combination of ab-initio and ad-hoc models, we introduce the first description of electric field profiles with intrabond resolution to support a characterization of single bond forces attending to its electrical origin. [...]
2017 - 10.1371/journal.pone.0185638
PloS one, Vol. 12, Núm. 10 (October 2017) , art. e0185638  
3.
13 p, 2.6 MB The Impact of Extra-Domain Structures and PostTranslational Modifications in the Folding/Misfolding Behaviour of the Third PDZ Domain of MAGUK Neuronal Protein PSD-95 / Murciano Calles, Javier (Universidad de Granada. Departamento de Química Física) ; Marin Argany, Marta (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Cobos, Eva S. (Universidad de Granada. Departamento de Química Física) ; Villegas Hernández, Sandra (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Martínez, José C. (Universidad de Granada. Departamento de Química Física)
The modulation of binding affinities and specificities by post-translational modifications located out from the binding pocket of the third PDZ domain of PSD-95 (PDZ3) has been reported recently. It is achieved through an intra-domain electrostatic network involving some charged residues in the β2-β3 loop (were a succinimide modification occurs), the α3 helix (an extra-structural element that links the PDZ3 domain with the following SH3 domain in PSD-95, and contains the phosphorylation target Tyr397), and the ligand peptide. [...]
2014 - 10.1371/journal.pone.0098124
PloS one, Vol. 9, Num. 5 (2014) , p. e98124  
4.
9 p, 1.3 MB Probing a polar cluster in the retinal binding pocket of bacteriorhodopsin by a chemical design approach / Simón Vázquez, Rosana (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Domínguez, Marta (Universidade de Vigo. Departamento de Quimica Orgánica) ; Lórenz Fonfría, Víctor A. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Álvarez, Susana (Universidade de Vigo. Departamento de Quimica Orgánica) ; Bourdelande, J. L. (José Luis) (Universitat Autònoma de Barcelona. Departament de Química) ; De Lera, Ángel R (Universidade de Vigo. Departamento de Quimica Orgánica) ; Padrós, Esteve (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Peralvarez-Marin, Alex (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Bacteriorhodopsin has a polar cluster of amino acids surrounding the retinal molecule, which is responsible for light harvesting to fuel proton pumping. From our previous studies, we have shown that threonine 90 is the pivotal amino acid in this polar cluster, both functionally and structurally. [...]
2012 - 10.1371/journal.pone.0042447
PloS one, Vol. 7, Issue 8 (August 2012) , p. e42447  

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