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Resultats globals: 6 registres trobats en 0.03 segons.
Articles, 6 registres trobats
Articles 6 registres trobats  
1.
12 p, 1.9 MB Genetic perturbation of PU.1 binding and chromatin looping at neutrophil enhancers associates with autoimmune disease / Watt, Stephen (Human Genetics. Wellcome Sanger Institute. Genome Campus) ; Vasquez, Louella (Human Genetics. Wellcome Sanger Institute. Genome Campus) ; Walter, Klaudia (Human Genetics. Wellcome Sanger Institute. Genome Campus) ; Mann, Alice L. (Human Genetics. Wellcome Sanger Institute. Genome Campus) ; Kundu, Kousik (School of Clinical Medicine. University of Cambridge) ; Chen, Lu (Sichuan University) ; Sims, Ying (Human Genetics. Wellcome Sanger Institute. Genome Campus) ; Ecker, Simone (UCL Cancer Institute) ; Burden, Frances (National Health Service Blood and Transplant) ; Farrow, Samantha (National Health Service Blood and Transplant) ; Farr, Ben (Human Genetics. Wellcome Sanger Institute. Genome Campus) ; Iotchkova, Valentina (University of Oxford) ; Elding, Heather (Human Genetics. Wellcome Sanger Institute. Genome Campus) ; Mead, Daniel (Human Genetics. Wellcome Sanger Institute. Genome Campus) ; Tardaguila, Manuel (Human Genetics. Wellcome Sanger Institute. Genome Campus) ; Ponstingl, Hannes (Human Genetics. Wellcome Sanger Institute. Genome Campus) ; Richardson, David (European Molecular Biology Laboratory. European Bioinformatics Institute) ; Datta, Avik (European Molecular Biology Laboratory. European Bioinformatics Institute) ; Flicek, Paul (European Molecular Biology Laboratory. European Bioinformatics Institute) ; Clarke, Laura (European Molecular Biology Laboratory. European Bioinformatics Institute) ; Downes, Kate (National Health Service Blood and Transplant) ; Pastinen, Tomi (Center for Pediatric Genomic Medicine. Children's Mercy) ; Fraser, Peter (Florida State University) ; Frontini, Mattia (University of Exeter Medical School) ; Javierre, B. M (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Spivakov, Mikhail (Imperial College Faculty of Medicine) ; Soranzo, Nicole (University of Cambridge)
Neutrophils play fundamental roles in innate immune response, shape adaptive immunity, and are a potentially causal cell type underpinning genetic associations with immune system traits and diseases. [...]
2021 - 10.1038/s41467-021-22548-8
Nature communications, Vol. 12 Núm. 1 (january 2021) , p. 2298  
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2.
13 p, 1.6 MB MicroRNA-101 is repressed by EZH2 and its restoration inhibits tumorigenic features in embryonal rhabdomyosarcoma / Vella, Serena (Ospedale Pediatrico Bambino Gesù) ; Pomella, Silvia (Istituto Dermopatico dell'Immacolata) ; Leoncini, Pier Paolo (Ospedale Pediatrico Bambino Gesù) ; Colletti, Marta (Ospedale Pediatrico Bambino Gesù) ; Conti, Beatrice (Ospedale Pediatrico Bambino Gesù) ; Marquez, Victor E. (Frederick National Laboratory for Cancer Research) ; Strillacci, Antonio (University of Bologna) ; Roma, Josep (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Gallego, Soledad (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Milano, Giuseppe M. (Ospedale Pediatrico Bambino Gesù) ; Capogrossi, Maurizio C. (Istituto Dermopatico dell'Immacolata) ; Bertaina, Alice (Ospedale Pediatrico Bambino Gesù) ; Ciarapica, Roberta (Istituto Dermopatico dell'Immacolata) ; Rota, Rossella (Laboratory of Angiogenesis, Ospedale Pediatrico Bambino Gesù) ; Universitat Autònoma de Barcelona
Rhabdomyosarcoma (RMS) is a pediatric soft tissue sarcoma arising from myogenic precursors that have lost their capability to differentiate into skeletal muscle. The polycomb-group protein EZH2 is a Lys27 histone H3 methyltransferase that regulates the balance between cell proliferation and differentiation by epigenetically silencing muscle-specific genes. [...]
2015 - 10.1186/s13148-015-0107-z
Clinical Epigenetics, Vol. 7 (august 2015)  
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3.
16 p, 2.3 MB SIRT7 mediates L1 elements transcriptional repression and their association with the nuclear lamina / Vazquez Prat, Berta Nieves (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Thackray, J. K. (Department of Genetics. Human Genetics Institute of New Jersey. Rutgers University) ; Simonet, N. G. (Institut d'Investigació Biomèdica de Bellvitge) ; Chahar, S. (Montpellier Institute of Molecular Genetics (IGMM). CNRS. University of Montpellier) ; Kane-Goldsmith, N. (Department of Genetics. Human Genetics Institute of New Jersey. Rutgers University) ; Newkirk, S. J. (Department of Pharmaceutical Sciences. College of Pharmacy and Allied Health Professions. South Dakota State University) ; Lee, S. (Department of Pharmaceutical Sciences. College of Pharmacy and Allied Health Professions. South Dakota State University) ; Xing, J. (Department of Genetics. Human Genetics Institute of New Jersey. Rutgers University) ; Verzi, M. P. (Department of Genetics. Human Genetics Institute of New Jersey. Rutgers University) ; An, W. (Department of Pharmaceutical Sciences. College of Pharmacy and Allied Health Professions. South Dakota State University) ; Vaquero, Alejandro (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Tischfield, J. A. (Department of Genetics. Human Genetics Institute of New Jersey. Rutgers University) ; Serrano, L. (Department of Genetics. Human Genetics Institute of New Jersey. Rutgers University) ; Universitat Autònoma de Barcelona
Long interspersed elements-1 (LINE-1, L1) are retrotransposons that hold the capacity of self-propagation in the genome with potential mutagenic outcomes. How somatic cells restrict L1 activity and how this process becomes dysfunctional during aging and in cancer cells is poorly understood. [...]
2019 - 10.1093/nar/gkz519
Nucleic acids research, Vol. 47 Núm. 15 (january 2019) , p. 7870-7885  
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4.
58 p, 970.8 KB RiboTag : Ribosomal tagging strategy to analyze cell type specific mRNA expression in vivo / Sanz Iglesias, Elisenda (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Bean, Jonathan C. (University of Washington. Department of Pharmacology) ; Carey, Daniel P. (University of Washington. Department of Pharmacology) ; Quintana Romero, Albert (Universitat Autònoma de Barcelona. Institut de Neurociències) ; McKnight, G. Stanley (University of Washington. Department of Pharmacology)
Ribosome tagging has become a very useful in vivo approach for analyzing gene expression and mRNA translation in specific cell types that are difficult and time consuming to isolate by conventional methods. [...]
2019 - 10.1002/cpns.77
Current Protocols in Neuroscience, Vol. 88, issue 1 (June 2019) , e77  
Registre complet -
5.
15 p, 1.1 MB Circadian-related heteromerization of adrenergic and dopamine D4 receptors modulates melatonin synthesis and release in the pineal gland / González, Sergio (Universitat de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Moreno Delgado, David (Universitat de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Moreno, Estefanía (Universitat de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Pérez-Capote, Kamil (Universitat de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Franco, Rafael (Universitat de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Mallol, Josefa (Universitat de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Cortés, Antoni (Universitat de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Casadó, Vicent (Universitat de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Lluís, Carme (Universitat de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Ortiz de Pablo, Jordi (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Ferré, Sergi (National Institute on Drug Abuse (Baltimore, Estats Units d'Amèrica)) ; Canela, Enric I (Universitat de Barcelona. Departament de Bioquímica i Biologia Molecular) ; McCormick, Peter J. (Universitat de Barcelona. Departament de Bioquímica i Biologia Molecular)
The role of the pineal gland is to translate the rhythmic cycles of night and day encoded by the retina into hormonal signals that are transmitted to the rest of the neuronal system in the form of serotonin and melatonin synthesis and release. [...]
2012 - 10.1371/journal.pbio.1001347
PLoS biology, Vol. 10 Issue 6 (June 2012) , p. e1001347  
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6.
14 p, 2.7 MB KAP degradation by calpain is associated with CK2 phosphorylation and provides a novel mechanism for cyclosporine A-induced proximal tubule injury / Tornavaca i Làzaro, Olga (Hospital Universitari Vall d'Hebron) ; Sarró Tauler, Eduard (Hospital Universitari Vall d'Hebron) ; Pascual, Gloria (Hospital Universitari Vall d'Hebron) ; Bardají de Quixano, Beatriz (Hospital Universitari Vall d'Hebron) ; Montero, M. Ángeles (Hospital Universitari Vall d'Hebron) ; Salcedo, M. Teresa (Hospital Universitari Vall d'Hebron) ; Plana i Coll, Maria (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; López Hellín, Juan (Hospital Universitari Vall d'Hebron) ; Itarte, Emilio (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Meseguer Navarro, Anna (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
The use of cyclosporine A (CsA) is limited by its severe nephrotoxicity that includes reversible vasoconstrictor effects and proximal tubule cell injury, the latter associated whith chronic kidney disease progression. [...]
2011 - 10.1371/journal.pone.0025746
PloS one, Vol. 6, Issue 9 (September 2011) , p. e25746  
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