Resultats globals: 2 registres trobats en 0.02 segons.
Articles, 2 registres trobats
Articles 2 registres trobats  
1.
13 p, 6.6 MB Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination / Abreu, Carla M. (Memorial Sloan Kettering Cancer Center) ; Prakash, Rohit (Memorial Sloan Kettering Cancer Center) ; Romanienko, Peter J. (Rutgers-Cancer Institute of New Jersey) ; Roig, Ignasi (Ignasi) (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Keeney, Scott (Memorial Sloan Kettering Cancer Center) ; Jasin, Maria (Memorial Sloan Kettering Cancer Center) ; Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia
The DNA-damage repair pathway homologous recombination (HR) requires factors that promote the activity of strand-exchange protein RAD51 and its meiosis-specific homolog DMC1. Here we show that the Shu complex SWS1-SWSAP1, a candidate for one such HR regulator, is dispensable for mouse viability but essential for male and female fertility, promoting the assembly of RAD51 and DMC1 on early meiotic HR intermediates. [...]
2018 - 10.1038/s41467-018-06384-x
Nature communications, Vol. 9 (2018) , art. 3961  
2.
13 p, 297.8 KB Individual differences and the characterization of animal models of psychopathology : a strong challenge and a good opportunity / Armario Garcia, Antonio (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Nadal i Alemany, Roser (Universitat Autònoma de Barcelona. Institut de Neurociències)
Despite the development of valuable new techniques (i. e. , genetics, neuroimage) for the study of the neurobiological substrate of psychiatric diseases, there are strong limitations in the information that can be gathered from human studies. [...]
2013 - 10.3389/fphar.2013.00137
Frontiers in Pharmacology, Vol. 4, Núm. 137 (November 2013) , p. 1-13  

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