Results overview: Found 17 records in 0.02 seconds.
Articles, 17 records found
Articles 17 records found  1 - 10next  jump to record:
1.
11 p, 2.7 MB Genomic Scanning of Inbreeding Depression for Litter Size in Two Varieties of Iberian Pigs / Hervás Rivero, Carlos (Universidad de Zaragoza. Instituto Agroalimentario de Aragón) ; Srihi, Houssemeddine (Universidad de Zaragoza. Instituto Agroalimentario de Aragón) ; López Carbonell, David (Universidad de Zaragoza. Instituto Agroalimentario de Aragón) ; Casellas Vidal, Joaquim (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ; Ibañez-Escriche, Noelia (Universitat Politècnica de València. Instituto Universitario de Ciencia y Tecnología Animal) ; Negro, Sara (INGA FOOD S.A. Programa de Mejora Genética "Castua") ; Varona, Luis (Universidad de Zaragoza. Instituto Agroalimentario de Aragón)
Inbreeding depression is expected to be more pronounced in fitness-related traits, such as pig litter size. Recent studies have suggested that the genetic determinism of inbreeding depression may be heterogeneous across the genome. [...]
2023 - 10.3390/genes14101941
Genes, Vol. 14 (october 2023)  
2.
7 p, 1.1 MB Evidential segregation analysis for offspring sex ratio in rabbit and sheep populations / Casellas Vidal, Joaquim (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ; Vázquez-Gómez, Marta (Sorbonne Université) ; Id-Lahoucine, Samir (Scotland's Rural College. Department of Animal and Veterinary Sciences) ; de Hijas Villalba, Melani Martín (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments)
Offspring sex ratio has been found to be altered by environmental and genetic distortions in multiple species, against the Mendelian inheritance rules. However, little is known in livestock populations where it is essential to validate whether a polymorphic major gene with relevant effects may segregate in the target population. [...]
2023 - 10.1016/j.livsci.2023.105354
Livestock Science, Vol. 277 (november 2023) , p. 105354  
3.
15 p, 1.8 MB Past Connectivity but Recent Inbreeding in Cross River Gorillas Determined Using Whole Genomes from Single Hairs / Alvarez-Estape, Marina (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ; Pawar, Harvinder (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ; Fontsere, Claudia (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ; Trujillo, Amber (New York University. Department of Anthropology) ; Gunson, Jessica L. (New York University. Department of Anthropology) ; Bergl, Richard A. (North Carolina Zoo) ; Bermejo, Magdalena (Universitat de Barcelona. Departament d'Ecologia i Ciències Ambientals) ; Linder, Joshua M. (James Madison University. Department of Anthropology) ; McFarland, Kelley (Triton College) ; Oates, John F. (University of New York. Department of Anthropology City) ; Sunderland-Groves, Jacqueline L. (University of British Columbia . Department of Forest Resources Management) ; Orkin, Joseph (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ; Higham, James P. (New York University . Department of Anthropology) ; Viaud-Martinez, Karine A. (Illumina Laboratory Services) ; Lizano, Esther (Institut Català de Paleontologia Miquel Crusafont) ; Marques-Bonet, Tomas 1975- (Institut Català de Paleontologia Miquel Crusafont)
The critically endangered western gorillas (Gorilla gorilla) are divided into two subspecies: the western lowland (G. g. gorilla) and the Cross River (G. g. diehli) gorilla. Given the difficulty in sampling wild great ape populations and the small estimated size of the Cross River gorilla population, only one whole genome of a Cross River gorilla has been sequenced to date, hindering the study of this subspecies at the population level. [...]
2023 - 10.3390/genes14030743
Genes, Vol. 14, Issue 3 (March 2023) , art. 743  
4.
14 p, 3.2 MB Genomic patterns of homozygosity and inbreeding depression in Murciano-Granadina goats / Luigi Sierra, Maria Gracia (Centre de Recerca en Agrigenòmica) ; Fernández, Almudena (INIA. Departamento de Mejora Genética Animal) ; Martinez, Amparo (Universidad de Córdoba. Departamento de Genética) ; Guan, Dailu (Centre de Recerca en Agrigenòmica) ; Delgado Bermejo, Juan Vicente (Universidad de Córdoba. Departamento de Genética) ; Fernández Álvarez, Javier (Universidad de Córdoba. Departamento de Genética) ; Landi, Vincenzo (University of Bari ''Aldo Moro". Department of Veterinary Medicine) ; Such i Martí, Francesc Xavier (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ; Jordana i Vidal, Jordi (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ; Saura, María (INIA. Departamento de Mejora Genética Animal) ; Amills i Eras, Marcel (Centre de Recerca en Agrigenòmica)
Inbreeding depression can adversely affect traits related to fitness, reproduction and productive performance. Although current research suggests that inbreeding levels are generally low in most goat breeds, the impact of inbreeding depression on phenotypes of economic interest has only been investigated in a few studies based on genealogical data. [...]
2022 - 10.1186/s40104-022-00684-5
Journal of animal science and biotechnology, Vol. 13 (March 2022) , art. 35  
5.
14 p, 742.5 KB Insights from the rescue and breeding management of Cuvier's gazelle (Gazella cuvieri) through whole-genome sequencing / Alvarez-Estape, Marina (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ; Fontsere, Claudia (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ; Serres-Armero, Aitor (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ; Kuderna, Lukas (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ; Dobrynin, Pavel (ITMO University. Computer Technologies Laboratory) ; Guidara, Héla (Direction Générale des Forêts (Tunisia)) ; Pukazhenthi, Budhan S. (Smithsonian Conservation Biology Institute) ; Koepfli, Klaus-Peter (Smithsonian Conservation Biology Institute) ; Marques-Bonet, Tomas 1975- (Institut Català de Paleontologia Miquel Crusafont) ; Moreno, Eulalia (Estación Experimental de Zonas Áridas-CSIC. Departamento de Ecología Funcional y Evolutiva) ; Lizano, Esther (Institut Català de Paleontologia Miquel Crusafont)
Captive breeding programmes represent the most intensive type of ex situ population management for threatened species. One example is the Cuvier's gazelle programme that started in 1975 with only four founding individuals, and after more than four decades of management in captivity, a reintroduction effort was undertaken in Tunisia in 2016, to establish a population in an area historically included within its range. [...]
2022 - 10.1111/eva.13336
Evolutionary applications, Vol. 15, Issue 3 (March 2022) , p. 351-364  
6.
17 p, 5.3 MB Associations of autozygosity with a broad range of human phenotypes / Clark, David W. (University of Edinburgh) ; Okada, Yukinori (Osaka University, Suita) ; Moore, Kristjan H. S. (deCODE genetics/Amgen Inc., Reykjavik, Iceland) ; Mason, Dan (Bradford Teaching Hospitals NHS Trust, Bradford, UK) ; Pirastu, Nicola (University of Edinburgh, Usher Institute) ; Gandin, Ilaria (University of Trieste) ; Mattsson, Hannele (University of Helsinki) ; Barnes, Catriona L. K. (University of Edinburgh) ; Lin, Kuang (University of Oxford) ; Zhao, Jing Hua (University of Cambridge) ; Deelen, Patrick (University Medical Centre Groningen, University of Groningen) ; Rohde, Rebecca (University of North Carolina. Department of Epidemiology) ; Schurmann, Claudia (Ichan School of Medicine at Mount Sinai) ; Guo, Xiuqing (The Institute for Translational Genomics and Population Sciences, Torrance, California, USA) ; Giulianini, Franco (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ; Zhang, Weihua (Ealing Hospital, Middlesex) ; Medina-Gomez, Carolina (Erasmus University Medical Center) ; Karlsson, Robert (Karolinska Institutet (Estocolm, Suècia)) ; Bao, Yanchun (University of Essex) ; Bartz, Traci M. (University of Washington) ; Baumbach, Clemens (Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg) ; Biino, Ginevra (National Research Council of Italy) ; Bixley, Matthew J. (University of Otago) ; Brumat, Marco (University of Trieste) ; Chai, Jin-Fang (National University of Singapore, Singapore) ; Corre, Tanguy (Swiss Institute of Bioinformatics) ; Cousminer, Diana L. (University of Pennsylvania) ; Dekker, Annelot M. (Utrecht University) ; Eccles, David (Instituto de Investigación Biomédica de Málaga) ; van Eijk, Kristel R. (Utrecht University) ; Fuchsberger, Christian (Affiliated Institute of the University of Lübeck, Bolzano, Italy) ; Gao, He (Imperial College London) ; Germain, Marine (ICAN Institute for Cardiometabolism and Nutrition) ; Gordon, Scott D. (QIMR Berghofer Institute of Medical Research) ; de Haan, Hugoline G. (Leiden University Medical Center) ; Harris, Sarah E. (University of Edinburgh) ; Hofer, Edith (Medical University of Graz) ; Huerta-Chagoya, Alicia (CONACyT, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico, 03940 México) ; Igartua, Catherine (University of Chicago. Department of Human Genetics) ; Jansen, Iris E. (VU University Medical Center, Amsterdam Neuroscience. Alzheimer Center Department of Neurology) ; Jia, Yucheng (Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, 90502 USA) ; Kacprowski, Tim (TUM School of Life Sciences Weihenstephan, Technical University of Munich. Chair of Experimental Bioinformatics) ; Karlsson, Torgny (Uppsala University. Department of Immunology, Genetics and Pathology, Science for Life Laboratory) ; Kleber, Marcus E. (Heidelberg University. Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim) ; Li, Shengchao Alfred (Leidos Biomedical Research, Inc., Frederick National Lab for Cancer Research. Cancer Genomics Research Laboratory) ; Li-Gao, Ruifang (Leiden University Medical Center. Department of Clinical Epidemiology) ; Mahajan, Anubha (University of Oxford. Wellcome Centre for Human Genetics) ; Matsuda, Koichi (Graduate school of Frontier Sciences, The University of Tokyo. Department of Computational Biology and Medical Sciences) ; Meidtner, Karina (German Center for Diabetes Research (DZD)) ; Meng, Weihua (Medical Research Institute, Ninewells Hospital and School of Medicine, University of Dundee) ; Montasser, May E. (University of Maryland, School of Medicine. Program for Personalized and Genomic Medicine, Department of Medicine) ; van der Most, Peter J. (University of Groningen, University Medical Center Groningen. Department of Epidemiology) ; Munz, Matthias (Humboldt-Universität zu Berlin) ; Nutile, Teresa (Institute of Genetics and Biophysics A. Buzzati-Traverso - CNR) ; Palviainen, Teemu (Finnish Institute for Molecular Medicine, University of Helsinki) ; Prasad, Gauri (Genomics and Molecular Medicine Unit, CSIR-Institute of Genomics and Integrative Biology) ; Prasad, Rashmi B. (Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Lund University, Skåne University Hospital, Malmö, 20502 Sweden) ; Priyanka, Tallapragada Divya Sri (CSIR-Centre for Cellular and Molecular Biology. Genomic Research on Complex diseases (GRC Group)) ; Rizzi, Federica (University of Milano. Department of Health Sciences) ; Salvi, Erika (IRCCS Foundation Carlo Besta Neurological Institute. Neuroalgology Unit) ; Sapkota, Bishwa R. (University of Oklahoma Health Sciences Center. Department of Pediatrics, College of Medicine) ; Shriner, Daniel (National Human Genome Research Institute, National Institutes of Health. Center for Research on Genomics and Global Health) ; Skotte, Line (Statens Serum Institut. Department of Epidemiology Research) ; Smart, Melissa C. (Institute for Social and Economic Research, University of Essex) ; Smith, Albert Vernon (University of Iceland. Faculty of Medicine, School of Health Sciences) ; van der Spek, Ashley (Erasmus University Medical Center. Department of Epidemiology) ; Spracklen, Cassandra N. (University of North Carolina. Department of Genetics) ; Strawbridge, Rona J. (Karolinska Institutet. Cardiovascular Medicine Unit, Department of Medicine Solna, Centre for Molecular Medicine) ; Tajuddin, Salman M. (National Institute on Aging, National Institutes of Health. Laboratory of Epidemiology and Population Sciences) ; Trompet, Stella (Leiden University Medical Center. Section of Gerontology and Geriatrics, Department of Internal Medicine) ; Turman, Constance (Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health) ; Verweij, Niek (University of Groningen, University Medical Center Groningen, Department of Cardiology, Ther Netherlands) ; Viberti, Clara (University of Turin, Italy. Italian Institute for Genomic Medicine (IIGM) and Dept. Medical Sciences) ; Wang, Lihua (Washington University School of Medicine. Division of Statistical Genomics, Department of Genetics) ; Warren, Helen R. (William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London. Department of Clinical Pharmacology) ; Wootton, Robyn E. (School of Psychological Science, University of Bristol) ; Yanek, Lisa R. (Johns Hopkins University School of Medicine. Department of Medicine, GeneSTAR Research Program) ; Yao, Jie (Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, 90502 USA) ; Yousri, Noha A. (Alexandria University. Computer and Systems Engineering) ; Zhao, Wei (University of Michigan. Department of Epidemiology, School of Public Health) ; Adeyemo, Adebowale A. (National Human Genome Research Institute, National Institutes of Health. Center for Research on Genomics and Global Health) ; Afaq, Saima (Imperial College London. Department of Epidemiology and Biostatistics) ; Aguilar-Salinas, Carlos Alberto (Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud. Unidad de Investigacion de Enfermades Metabolicas) ; Akiyama, Masato (Graduate School of Medical Sciences, Kyushu University, Fukuoka. Department of Ophthalmology) ; Albert, Matthew L. (Genentech Inc. Department of Cancer Immunology) ; Allison, Matthew A. (UC San Diego School of Medicine. Division of Preventive Medicine, Department of Family Medicine and Public Health) ; Alver, Maris (University of Tartu, University of Tartu. Estonian Genome Center) ; Aung, Tin (Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Department of Ophthalmology) ; Azizi, Fereidoun (Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences. Endocrine Research Center) ; Bentley, Amy R. (National Human Genome Research Institute, National Institutes of Health. Center for Research on Genomics and Global Health) ; Boeing, Heiner (German Institute of Human Nutrition Potsdam-Rehbruecke. Department of Epidemiology) ; Boerwinkle, Eric (UTHealth School of Public Health, University of Texas. Health Science Center at Houston) ; Borja, Judith B. (USC-Office of Population Studies Foundation, Inc., Department of Nutrition and Dietetics, Talamban, University of San Carlos) ; de Borst, Gert J. (University Medical Center Utrecht) ; Bottinger, Erwin P. (Hasso Plattner Institute, Universität Potsdam. Digital Health Center) ; Broer, Linda (Erasmus University Medical Center. Department of Internal Medicine) ; Campbell, Harry (University of Edinburgh. Centre for Global Health Research, Usher Institute) ; Chanock, Stephen (National Cancer Institute, National Institutes of Health. Division of Cancer Epidemiology & Genetics) ; Chee, Miao-Li (Singapore Eye Research Institute, Singapore National Eye Centre, Singapore) ; Chen, Guanjie (National Human Genome Research Institute, National Institutes of Health. Center for Research on Genomics and Global Health) ; Chen, Yii Der Ida (Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA) ; Chen, Zhengming (University of Oxford. Nuffield Department of Population Health) ; Chiu, Yen-Feng (Institute of Population Health Sciences, National Health Research Institutes) ; Cocca, Massimiliano (Institute for Maternal and Child Health - IRCCS Burlo Garofolo) ; Collins, Francis S. (National Human Genome Research Institute, National Institutes of Health) ; Concas, Maria Pina (Institute for Maternal and Child Health - IRCCS Burlo Garofolo) ; Corley, Janie (University of Edinburgh. Department of Psychology) ; Cugliari, Giovanni (University of Turin, Italy. Italian Institute for Genomic Medicine (IIGM) and Dept. Medical Sciences) ; van Dam, Rob M. (Harvard T.H. Chan School of Public Health. Department of Nutrition) ; Damulina, Anna (Medical University of Graz. Clinical Division of Neurogeriatrics, Department of Neurology) ; Daneshpour, Maryam S. (Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences. Cellular and Molecular Endocrine Research Center) ; Day, Felix R. (University of Cambridge School of Clinical Medicine. MRC Epidemiology Unit) ; Delgado, Graciela E. (Heidelberg University. Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim) ; Dhana, Klodian (Rush University Medical Center. Department of Internal Medicine) ; Doney, Alexander S. F. (Molecular and Clinical Medicine, University of Dundee. MEMO Research) ; Dörr, Marcus (DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, 17475 Germany) ; Doumatey, Ayo P. (National Human Genome Research Institute, National Institutes of Health. Center for Research on Genomics and Global Health) ; Dzimiri, Nduna (King Faisal Specialist Hospital and Research Centre (Aràbia Saudita)) ; Ebenesersdóttir, S. Sunna (University of Iceland. Department of Anthropology) ; Elliott, Joshua (Imperial College London. Department of Epidemiology and Biostatistics) ; Elliott, Paul (Health Data Research UK - London, London, England) ; Ewert, Ralf (University Medicine Greifswald. Department of Internal Medicine B) ; Felix, Janine F. (Erasmus University Medical Center. Department of Pediatrics) ; Fischer, Krista (University of Tartu, University of Tartu. Estonian Genome Center) ; Freedman, Barry I (Wake Forest School of Medicine. Section on Nephrology, Department of Internal Medicine) ; Girotto, Giorgia (Institute for Maternal and Child Health - IRCCS Burlo Garofolo. Medical Genetics) ; Goel, Anuj (University of Oxford. Division of Cardiovascular Medicine, Radcliffe Department of Medicine) ; Gögele, Martin (Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano, 39100 Italy) ; Goodarzi, Mark O. (Cedars-Sinai Medical Center. Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine) ; Graff, Mariaelisa (University of North Carolina. Department of Epidemiology, Gillings School of Global Public Health) ; Granot-Hershkovitz, Einat (Hebrew University-Hadassah Medical Center. Braun School of Public Health) ; Grodstein, Francine (Harvard T.H. Chan School of Public Health. Department of Epidemiology) ; Guarrera, Simonetta (University of Turin, Italy. Italian Institute for Genomic Medicine (IIGM) and Dept. Medical Sciences) ; Gudbjartsson, Daniel F. (School of Engineering and Natural Sciences, University of Iceland) ; Guity, Kamran (Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences. Cellular and Molecular Endocrine Research Center) ; Gunnarsson, Bjarni (deCODE genetics/Amgen Inc., Reykjavik 101, Iceland) ; Guo, Yu (Chinese Academy of Medical Sciences) ; Hagenaars, Saskia P. (Institute of Psychiatry, Psychology & Neuroscience, King's College London. Social, Genetic and Developmental Psychiatry Centre) ; Haiman, Christopher A. (Keck School of Medicine, University of Southern California. Department of Preventive Medicine) ; Halevy, Avner (Hebrew University-Hadassah Medical Center. Braun School of Public Health) ; Harris, Tamara B. (National Institute on Aging, National Institutes of Health. Laboratory of Epidemiology and Population Sciences) ; Hedayati, Mehdi (Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences. Cellular and Molecular Endocrine Research Center) ; van Heel, David A. (Blizard Institute, Queen Mary University of London) ; Hirata, Makoto (Institute of Medical Science, The University of Tokyo. Laboratory of Genome Technology) ; Höfer, Imo (University Medical Center Utrecht) ; Hsiung, Chao Agnes (Institute of Population Health Sciences, National Health Research Institutes) ; Huang, Jinyan (Shanghai Institute of Hematology, State Key Laboratory Of Medical Genomics, Rui-jin Hospital, Shanghai Jiao Tong University School of Medicine) ; Hung, Yi-Jen (National Defense Medical Center. School of Medicine) ; Ikram, M. Arfan (Erasmus University Medical Center. Department of Epidemiology) ; Jagadeesan, Anuradha (University of Iceland. Department of Anthropology) ; Jousilahti, Pekka (National Institute for Health and Welfare. Unit of Public Health Promotion) ; Kamatani, Yoichiro (Kyoto University Graduate School of Medicine. Center for Genomic Medicine) ; Kanai, Masahiro (Harvard Medical School. Department of Biomedical Informatics) ; Kerrison, Nicola D. (University of Cambridge School of Clinical Medicine. MRC Epidemiology Unit) ; Kessler, Thorsten (Klinik für Herz- und Kreislauferkrankungen, Technische Universität München. Deutsches Herzzentrum München) ; Khaw, Kay-Tee (University of Cambridge. Department of Public Health and Primary Care) ; Khor, Chiea Chuen (Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore. Human Genetics) ; de Kleijn, Dominique P. V (University Medical Center Utrecht) ; Koh, Woon-Puay (Duke-NUS Medical School. Health Services and Systems Research) ; Kolcic, Ivana (University of Split. Centre for Global Health, Faculty of Medicine) ; Kraft, Peter (Harvard T.H. Chan School of Public Health. Department of Nutrition) ; Krämer, Bernhard K. (Heidelberg University. Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim) ; Kutalik, Zoltán (Swiss Institute of Bioinformatics) ; Kuusisto, Johanna (Kuopio University Hospital ( Finlàndia)) ; Langenberg, Claudia (University of Cambridge School of Clinical Medicine. MRC Epidemiology Unit) ; Launer, Lenore J. (National Institute on Aging, National Institutes of Health. Laboratory of Epidemiology and Population Sciences) ; Lawlor, Deborah A. (Population Health Science, Bristol Medical School, Bristol, BS8 2BY UK) ; Lee, I-Te (Chung Shan Medical University, Taichung, Taiwan. School of Medicine) ; Lee, Wen-Jane (Taichung Veterans General Hospital. Department of Medical Research) ; Lerch, Markus M. (University Medicine Greifswald. Department of Internal Medicine A) ; Li, Liming (Peking University Health Science Centre, Peking University. Department of Epidemiology and Biostatistics) ; Liu, Jianjun (Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore. Human Genetics) ; Loh, Marie (Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Department of Biochemistry) ; London, Stephanie J. (National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services) ; Loomis, Stephanie (Johns Hopkins Bloomberg School of Public Health. Department of Epidemiology) ; Lu, Yingchang (Icahn School of Medicine at Mount Sinai (Nova York, Estats Units d'Amèrica)) ; Luan, Jian'an (University of Cambridge School of Clinical Medicine. MRC Epidemiology Unit) ; Mägi, Reedik (University of Tartu, University of Tartu. Estonian Genome Center) ; Manichaikul, Ani W. (University of Virginia School of Medicine. Center for Public Health Genomics) ; Manunta, Paolo (Genomics of Renal Diseases and Hypertension Unit, IRCCS San Raffaele Scientific Institute, Università Vita Salute San Raffaele, Milano, 20132 Italy) ; Másson, Gísli (deCODE genetics/Amgen Inc., Reykjavik 101, Iceland) ; Matoba, Nana (Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa 230-0045 Japan) ; Mei, Xue W. (University of Oxford. Nuffield Department of Population Health) ; Meisinger, Christa (Helmholtz Zentrum München, Independent Research Group Clinical Epidemiology, Neuherberg, 85764 Germany) ; Meitinger, Thomas (DZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance) ; Mezzavilla, Massimo (Institute for Maternal and Child Health - IRCCS Burlo Garofolo. Medical Genetics) ; Milani, Lili (Institute of Genomics, University of Tartu. Estonian Genome Center) ; Millwood, Iona Y (University of Oxford. Nuffield Department of Population Health) ; Momozawa, Yukihide (Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa 230-0045 Japan) ; Moore, Amy (National Cancer Institute, National Institutes of Health. Division of Cancer Epidemiology & Genetics) ; Morange, Pierre-Emmanuel (Aix-Marseille University. INSERM UMR_S 1263, Center for CardioVascular and Nutrition research (C2VN)) ; Moreno-Macías, Hortensia (Universidad Autónoma Metropolitana. Departamento de Economía) ; Mori, Trevor A. (The University of Western Australia. Medical School) ; Morrison, Alanna C. (The University of Texas Health Science Center at Houston, School of Public Health, Department of Epidemiology, Human Genetics and Environmental Sciences) ; Muka, Taulant (Institute of Social and Preventive Medicine (ISPM), University of Bern) ; Murakami, Yoshinori (Institute of Medical Science, The University of Tokyo. Division of Molecular Pathology) ; Murray, Alison D. (The Institute of Medical Sciences, Aberdeen Biomedical Imaging Centre, University of Aberdeen) ; de Mutsert, Renée (Leiden University Medical Center. Department of Clinical Epidemiology) ; Mychaleckyj, Josyf C. (University of Virginia School of Medicine. Center for Public Health Genomics) ; Nalls, Mike A. (Data Tecnica International LLC, Glen Echo, MD 20812 USA) ; Nauck, Matthias (Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald) ; Neville, Matt J. (Oxford University Hospitals Trust. Oxford NIHR Biomedical Research Centre) ; Nolte, Ilja M. (University of Groningen, University Medical Center Groningen. Department of Epidemiology) ; Ong, Ken K. (University of Cambridge School of Clinical Medicine. Department of Paediatrics) ; Orozco, Lorena (Instituto Nacional de Medicina Genómica) ; Padmanabhan, Sandosh (Institute of Cardiovascular and Medical Sciences, University of Glasgow) ; Pálsson, Gunnar (deCODE genetics/Amgen Inc., Reykjavik, Iceland) ; Pankow, James S. (School of Public Health, University of Minnesota. Division of Epidemiology & Community Health) ; Pattaro, Cristian (Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano, 39100 Italy) ; Pattie, Alison (University of Edinburgh. Department of Psychology) ; Polasek, Ozren (Gen-info Ltd, Zagreb, Croatia, Zagreb, Select a Province Croatia) ; Poulter, Neil (Imperial College London, London. Imperial Clinical Trials Unit) ; Pramstaller, Peter P. (Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano, 39100 Italy) ; Quintana-Murci, Lluis (Institut Pasteur. Center of Bioinformatics, Biostatistics and Integrative Biology) ; Räikkönen, Katri (University of Helsinki, University of Helsinki. Department of Psychology and Logopedics, Faculty of Medicine) ; Ralhan, Sarju (Hero Heart Institute and Dyanand Medical College and Hospital) ; Rao, Dabeeru C. (Washington University School of Medicine. Division of Biostatistics) ; van Rheenen, Wouter (University Medical Centre Utrecht, Utrecht University. Department of Neurology, Brain Centre Rudolf Magnus) ; Rich, Stephen S. (University of Virginia School of Medicine. Center for Public Health Genomics) ; Ridker, Paul M. (Harvard Medical School) ; Rietveld, Cornelius A. (Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus University Rotterdam) ; Robino, Antonietta (Institute for Maternal and Child Health - IRCCS Burlo Garofolo) ; van Rooij, Frank J. A. (Erasmus University Medical Center. Department of Epidemiology) ; Ruggiero, Daniela (IRCCS Neuromed) ; Saba, Yasaman (Medical University of Graz. Gottfried Schatz Research Center (for Cell Signaling, Metabolism and Aging), Division of Molecular Biology and Biochemistry) ; Sabanayagam, Charumathi (Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Department of Ophthalmology) ; Sabater-Lleal, Maria (Institut d'Investigació Biomèdica Sant Pau) ; Sala, Cinzia Felicita (San Raffaele Research Institute, Milano, Italy) ; Salomaa, Veikko (National Institute for Health and Welfare. Department of Public Health Solutions) ; Sandow, Kevin (Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA) ; Schmidt, Helena (Medical University of Graz. Gottfried Schatz Research Center (for Cell Signaling, Metabolism and Aging), Division of Molecular Biology and Biochemistry) ; Scott, Laura J. (University of Michigan. Department of Biostatistics, and Center for Statistical Genetics) ; Scott, William R. (Imperial College London. Department of Epidemiology and Biostatistics) ; Sedaghati-Khayat, Bahareh (Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences. Cellular and Molecular Endocrine Research Center) ; Sennblad, Bengt (National Bioinformatics Infrastructure Sweden, Science for Life Laboratory, Uppsala University, Uppsala. Dept of Cell and Molecular Biology) ; van Setten, Jessica (University Medical Center Utrecht) ; Sever, Peter J. (International Centre for Circulatory Health, Imperial College London) ; Sheu, Wayne H-H (Institute of Medical Technology, National Chung-Hsing University) ; Shi, Yuan (Singapore Eye Research Institute, Singapore National Eye Centre, Singapore) ; Shrestha, Smeeta (School of Basic and Applied Sciences, Dayananda Sagar University, Bangalore, Karnataka 560078 India) ; Shukla, Sharvari Rahul (Symbiosis Statistical Institute, Symbiosis International University) ; Sigurdsson, Jon K. (deCODE genetics/Amgen Inc., Reykjavik 101, Iceland) ; Sikka, Timo Tonis (University of Tartu, University of Tartu. Estonian Genome Center) ; Singh, Jai Rup (Panjab University) ; Smith, Blair H. (Ninewells Hospital and Medical School, University of Dundee. Division of Population Health Sciences) ; Stančáková, Alena (Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland) ; Stanton, Alice (RCSI Molecular & Cellular Therapeutics (MCT), Royal College of Surgeons in Ireland, RCSI Education & Research Centre, Beaumont Hospital, Dublin 9, Ireland) ; Starr, John M. (University of Edinburgh. Alzheimer Scotland Dementia Research Centre) ; Stefansdottir, Lilja (deCODE genetics/Amgen Inc., Reykjavik 101, Iceland) ; Straker, Leon (School of Physiotherapy and Exercise Science, Faculty of Health Sciences, Curtin University) ; Sulem, Patrick (deCODE genetics/Amgen Inc., Reykjavik 101, Iceland) ; Sveinbjornsson, Gardar (deCODE genetics/Amgen Inc., Reykjavik 101, Iceland) ; Swertz, Morris A. (Department of Genetics, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands, Groningen, Groningen, 9700 RB The Netherlands) ; Taylor, Adele M. (University of Edinburgh. Department of Psychology) ; Taylor, Kent D. (Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA) ; Terzikhan, Natalie (Ghent University Hospital. (Bèlgica)) ; Tham, Yih-Chung (Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore) ; Thorleifsson, Gudmar (deCODE genetics/Amgen Inc., Reykjavik 101, Iceland) ; Thorsteinsdottir, Unnur (University of Iceland. Faculty of Medicine, School of Health Sciences) ; Tillander, Annika (Karolinska Institutet (Estocolm, Suècia). Department of Medical Epidemiology and Biostatistics) ; Tracy, Russell P. (University of Vermont. Department of Pathology) ; Tusié-Luna, Teresa (Unidad De Biología Molecular y Medicina Genómica, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán) ; Tzoulaki, Ioanna (University of Ioannina Medical School. Department of Hygiene and Epidemiology) ; Vaccargiu, Simona (Institute of Genetic and Biomedical Research - Support Unity, National Research Council of Italy) ; Vangipurapu, Jagadish (Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland) ; Veldink, Jan (University Medical Centre Utrecht, Utrecht University. Department of Neurology, Brain Centre Rudolf Magnus) ; Vitart, Veronique (Institute of Genetics and Molecular Medicine, University of Edinburgh. MRC Human Genetics Unit) ; Völker, Uwe (DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, 17475 Germany) ; Vuoksimaa, Eero (Institute for Molecular Medicine Finland (FIMM), University of Helsinki) ; Wakil, Salma M. (King Faisal Specialist Hospital and Research Centre (Aràbia Saudita)) ; Waldenberger, Melanie (Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764 Germany) ; Wander, Gurpreet S. (Hero DMC Heart Institute, Dayanand Medical College & Hospital. Department of Cardiology) ; Wang, Ya Xing (Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Lab) ; Wareham, Nicholas J. (University of Cambridge School of Clinical Medicine. MRC Epidemiology Unit) ; Wild, Sarah (Usher Institute of Population Health and Informatics, University of Edinburgh. Centre for Population Health Sciences) ; Yajnik, Chittaranjan S. (Diabetes Unit, K.E.M. Hospital Research Centre) ; Yuan, Jian-Min (Graduate School of Public Health, University of Pittsburgh. Department of Epidemiology) ; Zeng, Lingyao (Klinik für Herz- und Kreislauferkrankungen, Technische Universität München. Deutsches Herzzentrum München) ; Zhang, Liang (Singapore Eye Research Institute, Singapore National Eye Centre, Singapore) ; Zhou, Jie (National Human Genome Research Institute, National Institutes of Health. Center for Research on Genomics and Global Health) ; Amin, Najaf (Erasmus University Medical Center. Department of Epidemiology) ; Asselbergs, Folkert W. (Farr Institute of Health Informatics Research and Institute of Health Informatics, University College London) ; Bakker, Stephan J. L. (Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, 9713GZ The Netherlands) ; Becker, Diane M. (Johns Hopkins University School of Medicine. Department of Medicine, GeneSTAR Research Program) ; Lehne, Benjamin (Imperial College London. Department of Epidemiology and Biostatistics) ; Bennett, David A. (Rush University Medical Center. Department of Neurological Sciences) ; van den Berg, Leonard H. (University Medical Centre Utrecht, Utrecht University. Department of Neurology, Brain Centre Rudolf Magnus) ; Berndt, Sonja (National Cancer Institute, National Institutes of Health. Division of Cancer Epidemiology & Genetics) ; Bharadwaj, Dwaipayan (School of Biotechnology, Jawaharlal Nehru University. Systems Genomics Laboratory) ; Bielak, Lawrence F. (University of Michigan. Department of Epidemiology, School of Public Health) ; Bochud, Murielle (University of Lausanne. Center for Primary Care and Public Health (Unisanté)) ; Boehnke, Michael (University of Michigan. Department of Biostatistics, and Center for Statistical Genetics) ; Bouchard, Claude (Pennington Biomedical Research Center) ; Bradfield, Jonathan Paul (Quantinuum Research LLC, San Diego, CA 92101 USA) ; Brody, Jennifer A. (University of Washington. Cardiovascular Health Research Unit, Department of Medicine) ; Campbell, Archie (Institute of Genetics & Molecular Medicine, University of Edinburgh. Centre for Genomic & Experimental Medicine) ; Carmi, Shai (Hebrew University-Hadassah Medical Center. Braun School of Public Health) ; Caulfield, Mark (William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London. Department of Clinical Pharmacology) ; Cesarini, David (Research Institute for Industrial Economics (IFN)) ; Chambers, John C. (Imperial College Healthcare NHS Trust, London) ; Chandak, Giriraj Ratan (CSIR-Centre for Cellular and Molecular Biology. Genomic Research on Complex diseases (GRC Group)) ; Cheng, Ching-Yu (Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Department of Ophthalmology) ; Ciullo, Marina (IRCCS Neuromed) ; Cornelis, Marilyn (Northwestern University Feinberg School of Medicine. Department of Preventive Medicine) ; Cusi, Daniele (Bio4Dreams Scientific Unit, Bio4Dreams SRL, Bio4Dreams - business nursery for life sciences, Milano, 20121 Italy) ; Smith, George Davey (Population Health Science, Bristol Medical School, Bristol, BS8 2BY UK) ; Deary, Ian J. (University of Edinburgh. Department of Psychology) ; Dorajoo, Rajkumar (Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore. Human Genetics) ; van Duijn, Cornelia M. (Erasmus University Medical Center. Department of Epidemiology) ; Ellinghaus, David (Christian-Albrechts-University of Kiel. Institute of Clinical Molecular Biology) ; Erdmann, Jeanette (University of Lübeck. Institute for Cardiogenetics) ; Eriksson, Johan G. (Vasa Central Hospital) ; Evangelou, Evangelos (University of Ioannina Medical School. Department of Hygiene and Epidemiology) ; Evans, Michele K. (National Institute on Aging, National Institutes of Health. Laboratory of Epidemiology and Population Sciences) ; Faul, Jessica D. (University of Michigan. Institute for Social Research) ; Feenstra, Bjarke (Statens Serum Institut. Department of Epidemiology Research) ; Feitosa, Mary (Washington University School of Medicine. Division of Statistical Genomics, Department of Genetics) ; Foisy, Sylvain (Montreal Heart Institute) ; Franke, Andre (Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel) ; Friedlander, Yechiel (Hebrew University-Hadassah Medical Center. Braun School of Public Health) ; Gasparini, Paolo (Institute for Maternal and Child Health - IRCCS Burlo Garofolo. Medical Genetics) ; Gieger, Christian (German Center for Diabetes Research (DZD)) ; Gonzalez, Clicerio (Centro de Estudios en Diabetes, Unidad de Investigacion en Diabetes y Riesgo Cardiovascular, Centro de Investigacion en Salud Poblacional, Instituto Nacional de Salud Publica) ; Goyette, Philippe (Montreal Heart Institute) ; Grant, Struan F. A. (Perelman School of Medicine, University of Pennsylvania. Department of Pediatrics) ; Griffiths, Lyn R. (Institute of Health and Biomedical Innovation, Queensland University of Technology. Genomics Research Centre, School of Biomedical Sciences) ; Groop, Leif (Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Lund University, Skåne University Hospital, Malmö, Sweden) ; Gudnason, Vilmundur (University of Iceland. Faculty of Medicine, School of Health Sciences) ; Gyllensten, Ulf (Uppsala University. Department of Immunology, Genetics and Pathology, Science for Life Laboratory) ; Hakonarson, Hakon (University of Pennsylvania. Perelman School of Medicine) ; Hamsten, Anders (Cardiovascular Medicine Unit, Department of Medicine Solna, Centre for Molecular Medicine, Stockholm, 171 76 Sweden) ; van der Harst, Pim (University of Groningen, University Medical Center Groningen, Department of Cardiology, Ther Netherlands) ; Heng, Chew-Kiat (Khoo Teck Puat - National University Children's Medical Institute, National University Health System) ; Hicks, Andrew A. (Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano, 39100 Italy) ; Hochner, Hagit (Hebrew University-Hadassah Medical Center. Braun School of Public Health) ; Huikuri, Heikki (Research Unit of Internal Medicine, Medical Research Center Oulu, University of Oulu and Oulu University Hospital) ; Hunt, Steven C. (University of Utah School of Medicine. Division of Epidemiology, Department of Internal Medicine) ; Jaddoe, Vincent W. V (Erasmus University Medical Center. Department of Pediatrics) ; De Jager, Philip L. (Cell Circuits Program, Broad Institute) ; Johannesson, Magnus (Stockholm School of Economics. Department of Economics) ; Johansson, Åsa (Uppsala University. Department of Immunology, Genetics and Pathology, Science for Life Laboratory) ; Jonas, Jost B. (University of Heidelberg) ; Jukema, J. Wouter (Leiden University Medical Center. Department of Cardiology) ; Junttila, Juhani (Research Unit of Internal Medicine, Medical Research Center Oulu, University of Oulu and Oulu University Hospital) ; Kaprio, Jaakko (University of Helsinki. Department of Public Health) ; Kardia, Sharon L. R. (University of Michigan. Department of Epidemiology, School of Public Health) ; Karpe, Fredrik (Oxford NIHR Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital) ; Kumari, Meena (Institute for Social and Economic Research, University of Essex) ; Laakso, Markku (Kuopio University Hospital ( Finlàndia)) ; van der Laan, Sander W. (University Medical Center Utrecht) ; Lahti, Jari (University of Helsinki, University of Helsinki. Helsinki Collegium for Advanced Studies) ; Laudes, Matthias (Universitätsklinikum Schleswig-Holstein (Alemanya)) ; Lea, Rodney A. (Institute of Health and Biomedical Innovation, Queensland University of Technology. Genomics Research Centre, School of Biomedical Sciences) ; Lieb, Wolfgang (Institute of Epidemiology and PopGen Biobank, University of Kiel) ; Lumley, Thomas (University of Auckland. Department of Statistics) ; Martin, Nicholas G. (QIMR Berghofer Institute of Medical Research) ; März, Winfried (Synlab Academy, Synlab Holding Deutschland GmbH, Mannheim, Germany) ; Matullo, Giuseppe (University of Turin, Italy. Italian Institute for Genomic Medicine (IIGM) and Dept. Medical Sciences) ; McCarthy, Mark I (Oxford NIHR Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital) ; Medland, Sarah Elizabeth (QIMR Berghofer Institute of Medical Research) ; Merriman, Tony R. (University of Otago. Department of Biochemistry) ; Metspalu, Andres (University of Tartu, University of Tartu. Estonian Genome Center) ; Meyer, Brian F. (King Faisal Specialist Hospital and Research Centre. Department of Genetics) ; Mohlke, Karen L. (University of North Carolina. Department of Genetics) ; Montgomery, Grant W. (Institute for Molecular Bioscience, The University of Queensland) ; Mook-Kanamori, Dennis (Leiden University Medical Center. Department of Public Health and Primary Care) ; Munroe, Patricia B. (Queen Mary University of London. Department of Clinical Pharmacology) ; North, Kari E. (University of North Carolina. Department of Epidemiology, Gillings School of Global Public Health) ; Nyholt, Dale R. (School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology) ; O'connell, Jeffery R. (University of Maryland, School of Medicine. Program for Personalized and Genomic Medicine, Department of Medicine) ; Ober, Carole (University of Chicago. Department of Human Genetics) ; Oldehinkel, Albertine J. (Interdisciplinary Center Psychopathology and Emotion Regulation, University of Groningen, University Medical Center Groningen. Department of Psychiatry) ; Palmas, Walter (Columbia University Medical Center. Department of Medicine) ; Palmer, Colin (Pat Macpherson Centre for Pharmacogenetics and Pharmacogenomics, The School of Medicine, University of Dundee) ; Pasterkamp, Gerard G. (University Medical Center Utrecht) ; Patin, Etienne (Institut Pasteur. Center of Bioinformatics, Biostatistics and Integrative Biology) ; Pennell, Craig E. (The University of Western Australia. Division of Obstetrics and Gynaecology) ; Pérusse, Louis (Institute of Nutrition and Functional Foods, Laval University) ; Peyser, Patricia A. (University of Michigan. Department of Epidemiology, School of Public Health) ; Pirastu, Mario (Institute of Genetic and Biomedical Research - Support Unity, National Research Council of Italy) ; Polderman, Tinca J. C. (Vrije Universiteit Amsterdam. Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research) ; Porteous, David J. (Institute of Genetics & Molecular Medicine, University of Edinburgh. Centre for Genomic & Experimental Medicine) ; Posthuma, Danielle (Amsterdam Universitair Medische Centra (Amsterdam, Països Baixos)) ; Psaty, Bruce M. (Kaiser Permanente Washington Health Research Institute) ; Rioux, John D. (Université de Montréal. Department of Medicine, Faculty of Medicine) ; Rivadeneira, Fernando (The Generation R Study Group, Erasmus University Medical Center) ; Rotimi, Charles (National Human Genome Research Institute, National Institutes of Health. Center for Research on Genomics and Global Health) ; Rotter, Jerome I (Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA) ; Rudan, Igor (University of Edinburgh. Centre for Global Health Research, Usher Institute) ; Den Ruijter, Hester M. (University Medical Center Utrecht) ; Sanghera, Dharambir K. (Oklahoma Center for Neuroscience, Oklahoma City, USA) ; Sattar, Naveed (Institute of Cardiovascular and Medical Sciences, University of Glasgow) ; Schmidt, Reinhold (Medical University of Graz. Clinical Division of Neurogeriatrics, Department of Neurology) ; Schulze, Matthias B. (Institute of Nutritional Sciences, University of Potsdam) ; Schunkert, Heribert (Deutsches Zentrum für Herz- und Kreislauferkrankungen (DZHK), Munich Heart Alliance, Munich, 80636 Germany) ; Scott, Robert A. (University of Cambridge School of Clinical Medicine. MRC Epidemiology Unit) ; Shuldiner, Alan R. (Regeneron Pharmaceuticals, Inc. Regeneron Genetics Center) ; Sim, Xueling (National University of Singapore, Singapore. Saw Swee Hock School of Public Health) ; Small, Neil (University of Bradford. Faculty of Health Studies) ; Smith, Jennifer A. (University of Michigan. Institute for Social Research) ; Sotoodehnia, Nona (University of Washington) ; Tai, E-Shyong (National University of Singapore. Duke-NUS Medical School) ; Teumer, Alexander (University Medicine Greifswald) ; Timpson, Nicholas J. (University of Bristol) ; Toniolo, Daniela (San Raffaele Research Institute, Milano, Italy) ; Tregouet, David-Alexandre (Sorbonne Universités) ; Tuomi, Tiinamaija (University of Helsinki. Research Program of Diabetes and Endocrinology) ; Vollenweider, Peter (Lausanne University Hospital) ; Wang, Carol A. (The University of Western Australia. Division of Obstetrics and Gynaecology) ; Weir, David R. (University of Michigan. Institute for Social Research) ; Whitfield, John B. (QIMR Berghofer Institute of Medical Research) ; Wijmenga, Cisca (Department of Genetics, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands, Groningen, Groningen, RB The Netherlands) ; Wong, Tien-Yin (Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore) ; Wright, John (Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Trust, Bradford, UK) ; Yang, Jingyun (Rush University Medical Center. Department of Neurological Sciences) ; Yu, Lei (Rush University Medical Center. Department of Neurological Sciences) ; Zemel, Babette S. (Children's Hospital of Philadelphia (Pennsilvània)) ; Zonderman, Alan B. (National Institute on Aging, National Institutes of Health. Laboratory of Epidemiology and Population Sciences) ; Perola, Markus (National Institute for Health and Welfare. Unit of Genomics and Biomarkers) ; Magnusson, Patrik K. E. (Karolinska Institutet (Estocolm, Suècia).) ; Uitterlinden, André G. (The Generation R Study Group, Erasmus University Medical Center) ; Kooner, Jaspal S. (Imperial College London) ; Chasman, Daniel I (Harvard Medical School) ; Loos, Ruth J. F. (The Icahn School of Medicine at Mount Sinai. The Mindich Child Health and Development Institute) ; Franceschini, Nora (University of North Carolina. Department of Epidemiology, Gillings School of Global Public Health) ; Franke, Lude (Department of Genetics, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands, Groningen, Groningen, The Netherlands) ; Haley, Chris S. (Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, Scotland) ; Hayward, Caroline (Institute of Genetics and Molecular Medicine, University of Edinburgh. MRC Human Genetics Unit) ; Walters, Robin G. (University of Oxford. Nuffield Department of Population Health) ; Perry, John R. B. (University of Cambridge School of Clinical Medicine. MRC Epidemiology Unit) ; Esko, Tōnu (Broad Institute, Broad Institute. Program in Medical and Population Genetics) ; Helgason, Agnar (University of Iceland. Department of Anthropology) ; Stefansson, Kari (University of Iceland. Faculty of Medicine, School of Health Sciences) ; Joshi, Peter K. (University of Edinburgh. Centre for Global Health Research, Usher Institute) ; Kubo, Michiaki (Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa 230-0045 Japan) ; Wilson, James F.. (Institute of Genetics and Molecular Medicine, University of Edinburgh. MRC Human Genetics Unit) ; Universitat Autònoma de Barcelona
In many species, the offspring of related parents suffer reduced reproductive success, a phenomenon known as inbreeding depression. In humans, the importance of this effect has remained unclear, partly because reproduction between close relatives is both rare and frequently associated with confounding social factors. [...]
2019 - 10.1038/s41467-019-12283-6
Nature communications, Vol. 10 (october 2019)  
7.
11 p, 829.8 KB Pedigree analysis of 220 almond genotypes reveals two world mainstream breeding lines based on only three different cultivars / Pérez de los Cobos, Felipe (Centre de Recerca en Agrigenòmica) ; Martínez-García, Pedro J (Consejo Superior de Investigaciones Científicas. Centro de Edafología y Biología Aplicada del Segura) ; Romero Aroca, Agusti Jordi (Institut de Recerca i Tecnologia Agroalimentàries) ; Miarnau, Xavier (Institut de Recerca i Tecnologia Agroalimentàries) ; Eduardo, Iban (Centre de Recerca en Agrigenòmica) ; Howad, Werner (Centre de Recerca en Agrigenòmica) ; Mnejja, Mourad (Centre de Recerca en Agrigenòmica) ; Dicenta, Federico (Consejo Superior de Investigaciones Científicas. Centro de Edafología y Biología Aplicada del Segura) ; Socias i Company, Rafel (Centro de Investigación y Tecnología Agroalimentaria de Aragón) ; Rubio Cabetas, Maria J. (Centro de Investigación y Tecnología Agroalimentaria de Aragón) ; Gradziel, Thomas M. (University of California) ; Wirthensohn, Michelle (University of Adelaide. School of Agriculture, Food and Wine) ; Duval, Henri (Institut National de la Recherche Agronomique (França)) ; Holland, Doron (Agricultural Research Organization (Israel)) ; Arús i Gorina, Pere (Centre de Recerca en Agrigenòmica) ; Vargas, Francisco J. (Institut de Recerca i Tecnologia Agroalimentàries) ; Batlle, Ignasi (Institut de Recerca i Tecnologia Agroalimentàries)
Loss of genetic variability is an increasing challenge in tree breeding programs due to the repeated use of a reduced number of founder genotypes. However, in almond, little is known about the genetic variability in current breeding stocks, although several cases of inbreeding depression have been reported. [...]
2021 - 10.1038/s41438-020-00444-4
Horticulture research, Vol. 8 (January 2021) , art. 11  
8.
16 p, 4.5 MB The identification of runs of homozygosity give a focus on the genetic diversity and the adaptation of the "Charolais de Cuba" cattle / Rodríguez Valera, Yoel (Universidad de Granma. Facultad de Ciencias Agropecuarias) ; Rocha, Dominique (Institut national de la recherche agronomique. Génétique Animale et Biologie Intégrative) ; Naves, Michel (Institut National de la Recherche Agronomique (França)) ; Renand, Gilles (Institut national de la recherche agronomique. Génétique Animale et Biologie Intégrative) ; Pérez-Pineda, Eliecer (Universidad de Granma. Facultad de Ciencias Agropecuarias) ; Ramayo-Caldas, Yuliaxis (Institut de Recerca i Tecnologia Agroalimentàries) ; Ramos-Onsins, Sebastian (Centre de Recerca en Agrigenòmica)
Inbreeding and effective population size (Ne) are fundamental indicators for the management and conservation of genetic diversity in populations. Genomic inbreeding gives accurate estimates of inbreeding, and the Ne determines the rate of the loss of genetic variation. [...]
2020 - 10.3390/ani10122233
Animals, Vol. 10, issue 12 (Dec. 2020) , art. 2233  
9.
19 p, 6.2 MB Extreme genomic erosion after recurrent demographic bottlenecks in the highly endangered Iberian lynx / Abascal, Federico (Centro Nacional de Investigaciones Oncológicas) ; Corvelo, André (Centre Nacional d'Anàlisi Genòmica) ; Cruz, Fernando (Centre Nacional d'Anàlisi Genòmica) ; Villanueva-Cañas, J. L. (Institut Hospital del Mar d'Investigacions Mèdiques) ; Vlasova, Anna (Centre de Regulació Genòmica) ; Marcet-Houben, Marina (Centre de Regulació Genòmica) ; Martínez-Cruz, B. (Estación Biológica de Doñana) ; Cheng, J. Y. (Aarhus University. Bioinformatics Research Centre) ; Prieto, P. (Centre de Regulació Genòmica) ; Quesada, V. (Universidad de Oviedo. Instituto Universitario de Oncología) ; Quilez, J. (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ; Li, G. (Texas A;M University. Department of Veterinary Integrative Biosciences) ; García, Francisca (Universitat Autònoma de Barcelona. Servei de Cultius Cel·lulars, Producció d'Anticossos i Citometria) ; Rubio-Camarillo, M. (Centro Nacional de Investigaciones Oncológicas) ; Frias, Leonor (Centre Nacional d'Anàlisi Genòmica) ; Ribeca, Paolo (Centre Nacional d'Anàlisi Genòmica) ; Capella-Gutiérrez, Salvador (Centre de Regulació Genòmica) ; Rodríguez, J. M. (Centro Nacional de Investigaciones Oncológicas) ; Câmara, F. (Centre de Regulació Genòmica) ; Lowy, Ernesto (Centre de Regulació Genòmica) ; Cozzuto, Luca (Centre de Regulació Genòmica) ; Erb, I. (Centre de Regulació Genòmica) ; Tress, M. L. (Centro Nacional de Investigaciones Oncológicas) ; Rodriguez-Ales, J. L. (Centre de Regulació Genòmica) ; Ruiz-Orera, J. (Institut Hospital del Mar d'Investigacions Mèdiques) ; Reverter, F. (Centre de Regulació Genòmica) ; Casas-Marce, M. (Estación Biológica de Doñana) ; Soriano, L. (Estación Biológica de Doñana) ; Arango, Javier R (Universidad de Oviedo. Departamento de Bioquímica y Biología Molecular) ; Derdak, Sophia (Centre Nacional d'Anàlisi Genòmica) ; Galán, Beatriz (Centro de Investigaciones Biológicas (Madrid)) ; Blanc, Julie (Centre Nacional d'Anàlisi Genòmica) ; Gut, Marta (Centre Nacional d'Anàlisi Genòmica) ; Lorente-Galdos, Belen (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ; Andrés Nieto, Marta (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; López-Otín, C. (Universidad de Oviedo. Departamento de Bioquímica y Biología Molecular) ; Valencia, A. (Centro Nacional de Investigaciones Oncológicas) ; Gut, I. (Centre Nacional d'Anàlisi Genòmica) ; García, J. L. (Centro de Investigaciones Biológicas (Madrid)) ; Guigó, R. (Centre de Regulació Genòmica) ; Murphy, W. J. (Texas A;M University. Department of Veterinary Integrative Biosciences) ; Ruiz-Herrera Moreno, Aurora (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Marques-Bonet, Tomas. 1975- (Centre Nacional d'Anàlisi Genòmica) ; Roma, Guglielmo (Centre de Regulació Genòmica) ; Notredame, C. (Centre de Regulació Genòmica) ; Mailund, Thomas (Aarhus University. Bioinformatics Research Centre) ; Albà, M. Mar (Institut Hospital del Mar d'Investigacions Mèdiques) ; Gabaldón, Toni (Centre de Regulació Genòmica) ; Alioto, Tyler Scott (Centre Nacional d'Anàlisi Genòmica) ; Godoy, J. A. (Estación Biológica de Doñana)
Background: Genomic studies of endangered species provide insights into their evolution and demographic history, reveal patterns of genomic erosion that might limit their viability, and offer tools for their effective conservation. [...]
2016 - 10.1186/s13059-016-1090-1
Genome biology, Vol. 17 (2016) , art. 251  
10.
8 p, 990.0 KB The genome sequencing of an albino Western lowland gorilla reveals inbreeding in the wild / Prado-Martinez, Javier (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ; Hernando Herraez, Irene (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ; Lorente-Galdos, Belen (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ; Dabad, Marc (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ; Ramírez, Óscar (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ; Baeza Delgado, Carlos (Universitat de València. Departament de Bioquímica i Biologia Molecular) ; Morcillo-Suarez, Carlos (Universitat Pompeu Fabra. Instituto Nacional de Bioinformatica) ; Alkan, Can (Bilkent University. Department of Computer Engineering) ; Hormozdiari, Fereydoun (University of Washington. Department of Genome Sciences) ; Raineri, Emanuele (Centre Nacional d'Anàlisi Genòmica) ; Estellé, Jordi (Centre Nacional d'Anàlisi Genòmica) ; Fernández, Marcos (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ; Valles, Mònica (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ; Ritscher, Lars (University of Leipzig. Institute of Biochemistry) ; Schöneberg, Torsten (University of Leipzig. Institute of Biochemistry) ; De la Calle-Mustienes, Elisa (Centro Andaluz de Biología del Desarrollo) ; Casillas Viladerrams, Sònia (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Rubio Acero, Raquel (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Melé, M. (Universitat Pompeu Fabra. Centre de Regulació Genòmica (CRG-UPF)) ; Engelken, Johannes (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ; Cáceres Aguilar, Mario (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Gomez-Skarmeta, José Luis (Centro Andaluz de Biología del Desarrollo) ; Gut, Marta (Centre Nacional d'Anàlisi Genòmica) ; Bertranpetit, Jaume (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ; Gut, Ivo (Centre Nacional d'Anàlisi Genòmica) ; Abello, Teresa (Zoo de Barcelona) ; Eichler, Evan E. (Howard Hugues Medical Institute) ; Mingarro, Ismael (Universitat de València. Departament de Bioquímica i Biologia Molecular) ; Lalueza-Fox, Carles (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ; Navarro, Arcadi, 1969- (Institució Catalana de Recerca i Estudis Avançats) ; Marques-Bonet, Tomas 1975- (Institució Catalana de Recerca i Estudis Avançats)
Background: the only known albino gorilla, named Snowflake, was a male wild born individual from Equatorial Guinea who lived at the Barcelona Zoo for almost 40 years. He was diagnosed with non-syndromic oculocutaneous albinism, i. [...]
2013 - 10.1186/1471-2164-14-363
BMC genomics, Vol. 14 (2013) , art. 363  

Articles : 17 records found   1 - 10next  jump to record:
Interested in being notified about new results for this query?
Set up a personal email alert or subscribe to the RSS feed.