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35 p, 1.3 MB |
New η3-Allylpalladium Complexes with Pyridylpyrazole Ligands : Synthesis, Characterization and Study of the Influence of N1 Substituents on the Apparent Allyl Rotation
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Montoya García, Vanessa (Universitat Autònoma de Barcelona. Departament de Química) ;
Pons Picart, Josefina (Universitat Autònoma de Barcelona. Departament de Química) ;
García-Antón, Jordi (Universitat Autònoma de Barcelona. Departament de Química) ;
Solans Monfort, Xavier (Universitat Autònoma de Barcelona. Departament de Química) ;
Font-Bardia, Mercè (Universitat de Barcelona. Unitat de Difracció de Raig-X) ;
Ros i Badosa, Josep (Universitat Autònoma de Barcelona. Departament de Química)
The allylpalladium [Pd(η3-C3H5)(L)](BF4) (L = L1 (1), L2 (2), L3 (3), L4 (4)) complexes with pyridylpyrazole ligands 2-(5-phenyl-1H-pyrazol-3-yl)pyridine (L1), 2-(1-ethyl-5-phenyl-1H-pyrazol-3-yl)pyridine (L2), 2-(1-octyl-5-phenyl)-1H-pyrazol-3-yl)pyridine (L3), and 2-(5-phenyl-3-(pyridin-2-yl)pyrazol-1-yl)ethanol (L4) were synthesized from the appropriate pyridylpyrazole ligand and [Pd(η3-C3H5)Cl]2 in the presence of AgBF4. [...]
2007 -  10.1021/om070093u
Organometallics, Vol. 26, Issue 13 (June 2007) , p. 3183-3190
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8 p, 1.3 MB |
The Role of Digital Rectal Examination Prostate Volume Category in the Early Detection of Prostate Cancer : Its Correlation with the Magnetic Resonance Imaging Prostate Volume
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Morote Robles, Juan (Universitat Autònoma de Barcelona. Departament de Cirurgia) ;
Picola, Natàlia (Hospital Universitari de Bellvitge) ;
Muñoz-Rodríguez, Jesús (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Paesano, Nahuel (Clinica Creu Blanca) ;
Ruiz-Plazas, Xavier (Hospital Universitari Joan XXIII de Tarragona) ;
Muñoz-Rivero, Marta V. (Hospital Universitari Arnau de Vilanova) ;
Celma, Ana (Universitat Autònoma de Barcelona. Departament de Cirurgia) ;
García-de Manuel, Gemma (Hospital Universitari de Girona Doctor Josep Trueta) ;
Miró, Berta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Abascal, Jose Maria (Parc de Salut MAR de Barcelona) ;
Servian, Pol (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
To relate the prostate volume category (PVC) assessed with digital rectal examination (DRE)-small, median, and large-and the prostate volumes (PVs) assessed with magnetic resonance imaging (MRI) and transrectal ultrasound (TRUS). [...]
2024 - 10.5534/wjmh.230028
The world journal of men's health, Vol. 42 (january 2024) , p. 441-448
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8 p, 208.5 KB |
Quality of Life and the Experience of Living with Early-Stage Alzheimer's Disease
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Villarejo-Galende, Alberto (Instituto de Salud Carlos III) ;
García-Arcelay, E. (Roche Farma) ;
Piñol-Ripoll, G. (Hospital de Santa Maria (Lleida, Catalunya)) ;
Del Olmo-Rodríguez, A. (Hospital Universitari Doctor Peset (València)) ;
Viñuela, F. (Hospital Universitario Virgen Macarena) ;
Boada, M. (Universitat Internacional de Catalunya) ;
Franco-Macías, E. (Instituto de Biomedicina de Sevilla) ;
Ibañez De La Peña, A. (Policlínica Guipúzcoa) ;
Riverol, M. (Universidad de Navarra) ;
Puig-Pijoan, Albert (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Abizanda-Soler, Pedro (Complejo Hospitalario Universitario de Albacete) ;
Arroyo, Rafael (Hospital Universitario Quirónsalud) ;
Baquero-Toledo, M. (Hospital Universitari i Politècnic la Fe) ;
Feria-Vilar, I. (Complejo Hospitalario Universitario de Albacete) ;
Balasa, M. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Berbel, Á. (Hospital Central de la Cruz Roja) ;
Rodríguez-Rodríguez, E. (Universidad de Cantabria) ;
Vieira-Campos, A. (Hospital Universitario de la Princesa) ;
García-Ribas, G. (Instituto de Investigación Hospital 12 de Octubre) ;
Rodrigo-Herrero, S. (Instituto de Investigación Hospital 12 de Octubre) ;
Terrancle, Á. (Roche Farma) ;
Prefasi, D. (Roche Farma) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Maurino, J. (Roche Farma) ;
Universitat Autònoma de Barcelona
Background: There is a need to better understand the experience of patients living with Alzheimer's disease (AD) in the early stages. Objective: The aim of the study was to evaluate the perception of quality of life in patients with early-stage AD. [...]
2022 - 10.3233/JAD-220696
Journal of Alzheimer's disease, Vol. 90 Núm. 2 (2022) , p. 719-726
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9 p, 440.0 KB |
Effect of 5-Alpha Reductase Inhibitors on Magnetic Resonance Imaging and Prostate Cancer Detection
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Morote Robles, Juan (Universitat Autònoma de Barcelona. Departament de Cirurgia) ;
Picola, Natàlia (Hospital Universitari de Bellvitge) ;
Muñoz-Rodríguez, Jesús (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Paesano, Nahuel (Clínica Creu Blanca) ;
Ruiz-Plazas, Xavier (Hospital Universitari Joan XXIII de Tarragona) ;
Muñoz-Rivero, Marta V. (Hospital Universitari Arnau de Vilanova) ;
Celma, Ana (Hospital Universitari Vall d'Hebron) ;
Manuel, Gemma García-de (Hospital Universitari de Girona Doctor Josep Trueta) ;
Miró, Berta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Servian, Pol (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Abascal, Jose Maria (Parc de Salut MAR de Barcelona)
Concerns exist regarding the effects of 5-alpha reductase inhibitors (5-ARIs) on multipa-rametric magnetic resonance imaging (mpMRI) and clinically significant prostate cancer (csPCa) detection. Our objective is to analyze the effect of 5-ARI on the prostate imaging-reporting and data system (PI-RADS) distribution and csPCa and insignificant PCa (iPCa) detection. [...]
2024 - 10.3390/biom14020193
Biomolecules, Vol. 14 (february 2024)
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8 p, 1.9 MB |
Obesity and Alzheimer's disease, does the obesity paradox really exist? A magnetic resonance imaging study
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Pegueroles, Jordi (Institut d'Investigació Biomèdica Sant Pau) ;
Jiménez, Amanda (Hospital Clínic i Provincial de Barcelona) ;
Vilaplana, Eduard (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Montal, Victor (Institut d'Investigació Biomèdica Sant Pau) ;
Carmona Iragui, María (Institut d'Investigació Biomèdica Sant Pau) ;
Pané, Adriana (Hospital Clínic i Provincial de Barcelona) ;
Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ;
Videla Toro, Laura (Institut d'Investigació Biomèdica Sant Pau) ;
Casajoana, Anna (Hospital de Barcelona-SCIAS) ;
Clarimón, Jordi (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Ortega, Emilio (Hospital Clínic i Provincial de Barcelona) ;
Vidal, Josep (Hospital Clínic i Provincial de Barcelona) ;
Blesa, Rafael (Institut d'Investigació Biomèdica Sant Pau) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
Mid-life obesity is an established risk factor for Alzheimer's disease (AD) dementia,whereas late-life obesity has been proposed as a protective state. Weight loss, whichpredates cognitive decline, might explain this obesity paradox on AD risk. [...]
2018 - 10.18632/oncotarget.26162
Oncotarget, Vol. 9 Núm. 78 (january 2018) , p. 34691-34698
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8 p, 2.5 MB |
Hyperpolarization-Enhanced NMR Spectroscopy of Unaltered Biofluids Using Photo-CIDNP
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Kuhn, Lars T. (Albert-Ludwigs-Universität Freiburg. Institut für Physikalische Chemie) ;
Weber, Stefan (Albert-Ludwigs-Universität Freiburg. Institut für Physikalische Chemie) ;
Bargon, Joachim (Rheinische Friedrich-Wilhelms-Universität Bonn. Institut für Physikalische und Theoretische Chemie) ;
Parella Coll, Teodor (Universitat Autònoma de Barcelona. Servei de Ressonància Magnètica Nuclear) ;
Pérez-Trujillo, Míriam (Universitat Autònoma de Barcelona. Servei de Ressonància Magnètica Nuclear)
The direct and unambiguous detection and identification of individual metabolite molecules present in complex biological mixtures constitute a major challenge in (bio)analytical research. In this context, nuclear magnetic resonance (NMR) spectroscopy has proven to be particularly powerful owing to its ability to provide both qualitative and quantitative atomic-level information on multiple analytes simultaneously in a noninvasive manner. [...]
2024 - 10.1021/acs.analchem.3c03215
Analytical chemistry, Vol. 96, Issue 1 (September 2024) , p. 102-109
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55 p, 707.1 KB |
Advances in the Use of Deep Learning for the Analysis of Magnetic Resonance Image in Neuro-Oncology
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Pitarch, Carla (Universitat Politècnica de Catalunya. Departament d'Informàtica) ;
Ungan, Gulnur Semahat (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Julià Sapé, Ma. Margarita (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Vellido, Alfredo (Universitat Politècnica de Catalunya. Departament d'Informàtica)
Machine Learning is entering a phase of maturity, but its medical applications still lag behind in terms of practical use. The field of oncological radiology (and neuro-oncology in particular) is at the forefront of these developments, now boosted by the success of Deep-Learning methods for the analysis of medical images. [...]
2024 - 10.3390/cancers16020300
Cancers, Vol. 16, Issue 2 (January 2024) , art. 300
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9 p, 745.8 KB |
The EMIF-AD Multimodal Biomarker Discovery study : Design, methods and cohort characteristics
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Bos, Isabelle (Maastricht University) ;
Vos, Stephanie (Maastricht University) ;
Vandenberghe, Rik (Katholieke Universiteit Leuven) ;
Scheltens, Philip (Amsterdam UMC. University Medical Center) ;
Engelborghs, Sebastiaan (University of Antwerp) ;
Frisoni, Giovanni (IRCCS Instituto Centro San Giovanni di Dio Fatebenefratelli) ;
Molinuevo, José Luis (Fundació Pasqual Maragall) ;
Wallin, Anders (Institute of Neuroscience and Physiology) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Popp, Julius (Lausanne University Hospital) ;
Martinez-Lage, Pablo (Centro de Investigación y Tecnología Agroalimentaria de Aragón) ;
Baird, Alison (University of Oxford) ;
Dobson, Richard (NIHR University College London Hospitals) ;
Legido-Quigley, Cristina (King's College London) ;
Sleegers, Kristel (University of Antwerp) ;
Van Broeckhoven, Christine (University of Antwerp) ;
Bertram, Lars (University of Oslo) ;
Ten Kate, Mara (Amsterdam UMC. University Medical Center) ;
Barkhof, Frederik (Amsterdam UMC. University Medical Center) ;
Zetterberg, Henrik (UK Dementia Research Institute) ;
Lovestone, Simon (University of Oxford) ;
Streffer, Johannes (Janssen Pharmaceutical Companies) ;
Visser, Pieter Jelle (Vrije Universiteit Amsterdam) ;
Universitat Autònoma de Barcelona
There is an urgent need for novel, noninvasive biomarkers to diagnose Alzheimer's disease (AD) in the predementia stages and to predict the rate of decline. Therefore, we set up the European Medical Information Framework for Alzheimer's Disease Multimodal Biomarker Discovery (EMIF-AD MBD) study. [...]
2018 - 10.1186/s13195-018-0396-5
Alzheimer's research & therapy, Vol. 10 Núm. 1 (june 2018) , p. 64
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10 p, 585.1 KB |
Water T2 could predict functional decline in patients with dysferlinopathy
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Moore, Ursula. (The John Walton Muscular Dystrophy Research Centre. Translational and Clinical Research Institute. Newcastle University and Newcastle Hospitals NHS Foundation Trust) ;
Caldas de A. Araújo, Ericky (NMR Laboratory. CEA/DRF/IBFJ/MIRCen) ;
Reyngoudt, Harmen (NMR Laboratory. CEA/DRF/IBFJ/MIRCen) ;
Gordish-Dressman, Heather (Pediatrics. Epidemiology and Biostatistics. George Washington University) ;
Smith, Fiona E. (Magnetic Resonance Centre. Translational and Clinical Research Institute. Newcastle University) ;
Wilson, Ian (Magnetic Resonance Centre. Translational and Clinical Research Institute. Newcastle University) ;
James, Meredith (The John Walton Muscular Dystrophy Research Centre. Translational and Clinical Research Institute. Newcastle University and Newcastle Hospitals NHS Foundation Trust) ;
Mayhew, Anna (The John Walton Muscular Dystrophy Research Centre. Translational and Clinical Research Institute. Newcastle University and Newcastle Hospitals NHS Foundation Trust) ;
Rufibach, Laura (Jain Foundation) ;
Day, John W. (Department of Neurology and Neurological Sciences. Stanford University School of Medicine) ;
Jones, Kristi J. (The Children's Hospital at Westmead and The University of Sydney) ;
Bharucha-Goebel, Diana (National Institutes of Health (Bethesda, Estats Units d'Amèrica)) ;
Salort-Campana, Emmanuelle (Service des maladies neuromusculaire et de la SLA. Hôpital de La Timone) ;
Pestronk, Alan (Washington University School of Medicine) ;
Walter, Maggie C. (Friedrich-Baur-Institute. Department of Neurology. Ludwig-Maximilians-University of Munich) ;
Paradas, Carmen (Instituto de Biomedicina de Sevilla) ;
Stojkovic, Tanya (Centre de référence des maladies neuromusculaires. Institut de Myologie. AP-HP. Sorbonne Université. Hôpital Pitié-Salpêtrière) ;
Mori-Yoshimura, Madoka (Department of Neurology. National Center Hospital. National Center of Neurology and Psychiatry) ;
Bravver, Elena (Neuroscience Institute. Carolinas Neuromuscular/ALS-MDA Center. Carolinas HealthCare System) ;
Pegoraro, Elena (Department of Neuroscience. University of Padova) ;
Mendell, Jerry R. (The Abigail Wexner Research Institute at Nationwide Children's Hospital) ;
Bushby, Kate (The John Walton Muscular Dystrophy Research Centre. Translational and Clinical Research Institute. Newcastle University and Newcastle Hospitals NHS Foundation Trust) ;
Blamire, Andrew (Magnetic Resonance Centre. Translational and Clinical Research Institute. Newcastle University) ;
Straub, Volker (Newcastle University) ;
Carlier, Pierre G. (Université Paris-Saclay. CEA. DRF. Service Hospitalier Frederic Joliot) ;
Diaz-Manera, Jordi (Institut d'Investigació Biomèdica Sant Pau)
Background: Water T2 (T2) mapping is increasingly being used in muscular dystrophies to assess active muscle damage. It has been suggested as a surrogate outcome measure for clinical trials. Here, we investigated the prognostic utility of T2 to identify changes in muscle function over time in limb girdle muscular dystrophies. [...]
2022 - 10.1002/jcsm.13063
Journal of Cachexia, Sarcopenia and Muscle, Vol. 13 Núm. 6 (december 2022) , p. 2888-2897
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12 p, 2.1 MB |
Glycoprotein profile assessed by1h-nmr as a global inflammation marker in patients with HIV infection. A prospective study
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Malo, Ana-Irene (Universitat Rovira i Virgili) ;
Rull, Anna (Universitat Rovira i Virgili) ;
Girona, Josefa (Universitat Rovira i Virgili) ;
Domingo, Pere (Institut d'Investigació Biomèdica Sant Pau) ;
Fuertes-Martín, Rocío (Universitat Rovira i Virgili) ;
Amigó, Núria (Universitat Rovira i Virgili) ;
Rodríguez-Borjabad, Cèlia (Universitat Rovira i Virgili) ;
Martínez-Micaelo, Neus (Universitat Rovira i Virgili) ;
Leal, Manuel (Viamed-Santa Ángela de la Cruz Hospital) ;
Peraire, Joaquim (Universitat Rovira i Virgili) ;
Correig, Xavier (Universitat Rovira i Virgili) ;
Vidal, Francesc (Universitat Rovira i Virgili) ;
Masana, Luisa (Universitat Rovira i Virgili) ;
Universitat Autònoma de Barcelona
Plasma glycoproteins are a composite biomarker of inflammation and can be detected byH-NMR. The aim of this study was to prospectively appraise the clinical value of plasma glycopro-teins assessed byH-NMR in people living with HIV (PLWH). [...]
2020 - 10.3390/jcm9051344
Journal of clinical medicine, Vol. 9 Núm. 5 (may 2020) , p. 1344
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