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1.
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6 p, 455.3 KB |
Molecular contamination of an animal facility during and after African swine fever virus infection
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Walczak, Marek (National Veterinary Research Institute. Department of Swine Diseases) ;
Szymankiewicz, Krzesimir (National Veterinary Research Institute. Department of Swine Diseases) ;
Rodriguez, Fernando (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Argilaguet, Jordi 1977- (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Gavrilov, Boris (Huvepharma. Biologics Development) ;
Żmudzki, Jacek (National Veterinary Research Institute. Department of Swine Diseases) ;
Kochanowski, Maciej (National Veterinary Research Institute. Department of Swine Diseases) ;
Juszkiewicz, Małgorzata (National Veterinary Research Institute. Department of Swine Diseases) ;
Szczotka-Bochniarz, Anna (National Veterinary Research Institute. Department of Swine Diseases)
The molecular contamination of an animal facility was investigated during and after an infection with highly pathogenic African swine fever virus (ASFV) among domestic pigs. The investigation evaluated the risk of indirect transmission of the disease and indicated points that may facilitate cleaning and disinfection processes. [...]
2023 -  10.2478/jvetres-2023-0065
Journal of Veterinary Research, Vol. 67 (december 2023) , p. 503-508
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2.
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6 p, 570.7 KB |
The Fractal Analysis of the Dynamics of International Arrivals in Tourism
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Shchelkunova, Liubov I. (Kharkiv National University of Construction Engineering and Architecture) ;
Yemets, Mariia (Odesa National Academy of Food Technology)
The article sets the task of determining the global and local fractal charac- teristics of the time series characterizing the development of international tourism, in order to identify the peculiarities of the dynamics of their evolution, properties of self-similarity, trend-tolerance, presence of «memory effect». [...]
Поставлено завдання визначення глобальних і локальних фрактальних характеристик часових рядів, які характеризують розвиток міжнародного туризму, з метою виявлення особливостей динаміки їх еволюції, властивостей самоподібності, трендостійкості, наявності «ефекту пам'яті». [...]
2019
Business Inform, Vol. 1 (2019)
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3.
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11 p, 1.5 MB |
Sown Diversity Effects on Yield and Resistance to Weed Invasion : Clues to Improve Mixture Design Under Climatic Change in the Mediterranean
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Ribas Artola, Àngela (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ;
Llovet Martin, Alba (Centre de Recerca Ecològica i d'Aplicacions Forestals) ;
Llurba, Rosa (Centre Tecnològic Forestal de Catalunya) ;
Connolly, John 1968- (University College Dublin) ;
Sebastiá Alvarez, Maria Teresa (Centre Tecnològic Forestal de Catalunya)
With the aim to improve mixture design, particularly in regions vulnerable to climate change, we tested several forage communities following the biodiversity-ecosystem function (BEF) framework. We sowed monocultures and 4-species mixtures from a pool of 7 forage species in a sub-Mediterranean region (Eastern Pyrenees) and assessed the diversity effects on yield and resistance to weed invasion. [...]
2023 - 10.1016/j.agee.2023.108601
Agriculture, ecosystems & environment, Vol. 356 (October 2023) , art. 108601
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4.
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20 p, 1.2 MB |
Real-World Treatment Patterns and Clinical Outcomes of Baricitinib in Rheumatoid Arthritis Patients in Spain : Results of a Multicenter, Observational Study in Routine Clinical Practice (The ORBIT-RA Study)
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Hernández-Cruz, Blanca (Hospital Universitario Virgen Macarena (Sevilla, Andalusia)) ;
Rosas, José (Hospital Marina Baixa. Servei de Reumatologia) ;
Díaz Torne, César (Institut d'Investigació Biomèdica Sant Pau) ;
Belzunegui, Joaquín (Hospital Universitario Donostia. Servicio de Reumatología) ;
García-Vicuña, Rosario (Hospital Universitario de La Princesa. Servicio de Reumatología. IIS-IP) ;
Inciarte-Mundo, José (Hospital Clínic i Provincial de Barcelona. Unitat d'Artritis. Servei de Reumatologia) ;
Pons, Ana (Hospital Marina Baixa. Servei de Reumatologia) ;
Millán, Ana M. (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Jeria-Navarro, Sicylle (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Valero, Jesús A. (Hospital Universitario Donostia. Servicio de Reumatología) ;
García-Castañeda, Noelia (Hospital Universitario de La Princesa. Servicio de Reumatología. IIS-IP) ;
Valero Martínez, Cristina (Hospital Universitario de La Princesa. Servicio de Reumatología. IIS-IP) ;
Llorente Cubas, Irene (Hospital Universitario de La Princesa. Servicio de Reumatología. IIS-IP) ;
Calvo, Alberto (Hospital Universitario de La Princesa. Servicio de Reumatología. IIS-IP) ;
Díaz-Cerezo, Silvia (Lilly Spain. Medical Department) ;
Núñez, Mercedes (Lilly Spain. Medical Department)
Introduction: Baricitinib is an oral Janus kinase (JAK)1/JAK2 inhibitor approved to treat rheumatoid arthritis (RA). This study aimed to investigate patients' characteristics, prescription patterns, effectiveness, and treatment persistence in patients receiving baricitinib in real-world practice in Spain. [...]
2022 - 10.1007/s40744-021-00423-8
Rheumatology and Therapy, Vol. 9 Núm. 2 (april 2022) , p. 589-608
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5.
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12 p, 524.6 KB |
Autopsy Study Defines Composition and Dynamics of the HIV-1 Reservoir after Allogeneic Hematopoietic Stem Cell Transplantation with CCR5Δ32/Δ32 Donor Cells
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Huyveneers, Laura E. P. (University Medical Center Utrecht) ;
Bruns, Anke (University Medical Center Utrecht) ;
Stam, Arjen (University Medical Center Utrecht) ;
Ellerbroek, Pauline (University Medical Center Utrecht) ;
de Jong, Dorien (University Medical Center Utrecht) ;
Nagy, Noémi A. (University Medical Center Utrecht) ;
Gumbs, Stephanie B. H. (University Medical Center Utrecht) ;
Tesselaar, Kiki (University Medical Center Utrecht) ;
Bosman, Kobus (University Medical Center Utrecht) ;
Salgado, Maria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Hütter, Gero (DKMS CC) ;
Brosens, Lodewijk A. A. (University Medical Center Utrecht) ;
Kwon, Mi (Hospital General Universitario Gregorio Marañón) ;
Diez Martin, Jose (Hospital General Universitario Gregorio Marañón) ;
van der Meer, Jan T. M. (Amsterdam UMC) ;
de Kort, Theun M. (Leiden University Medical Center) ;
Sáez-Cirión, Asier (Université Paris Cité) ;
Schulze zur Wiesch, Julian (UMC Hamburg-Eppendorf) ;
Boelens, Jaap Jan (Memorial Sloan Kettering Cancer Center) ;
Martínez Picado, Francisco Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Kuball, Jurgen (University Medical Center Utrecht) ;
Wensing, Annemarie M. J. (University Medical Center Utrecht) ;
Nijhuis, Monique (University Medical Center Utrecht)
Allo-HSCT with CCR5Δ32/Δ32 donor cells is the only curative HIV-1 intervention. We investigated the impact of allo-HSCT on the viral reservoir in PBMCs and post-mortem tissue in two patients. IciS-05 and IciS-11 both received a CCR5Δ32/Δ32 allo-HSCT. [...]
2022 - 10.3390/v14092069
Viruses, Vol. 14 (september 2022)
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8 p, 907.6 KB |
Comparison of Reverse Transcription (RT)-Quantitative PCR and RT-Droplet Digital PCR for Detection of Genomic and Subgenomic SARS-CoV-2 RNA
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Moron-Lopez, Sara (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Riveira-Muñoz, Eva (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Urrea, Víctor (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Gutiérrez-Chamorro, Lucía (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Avila-Nieto, Carlos (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Noguera-Julian, Marc (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Mitjà, Oriol (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Mateu, Lourdes (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Massanella, Marta (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Ballana, Ester (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Martínez Picado, Francisco Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Universitat Autònoma de Barcelona
Most individuals acutely infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibit mild symptoms. However, 10 to 20% of those infected develop long-term symptoms, referred to as post-coronavirus disease 2019 (COVID-19) condition (PCC). [...]
2023 - 10.1128/spectrum.04159-22
Microbiology Spectrum, Vol. 11 (march 2023)
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14 p, 2.9 MB |
A male mouse model of WIN 55,212-2 self-administration to study cannabinoid addiction
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Cajiao-Manrique, María del Mar (Universitat Pompeu Fabra. Laboratori de Neurofarmacologia) ;
Maldonado, Rafael 1961- (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Martín-García, Elena 1975- (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut)
We have established for the first time a mouse model of cannabinoid addiction using WIN 55,212-2 intravenous self-administration (0. 0125 mg/kg/infusion) in C57Bl/6J mice. This model allows to evaluate the addiction criteria by grouping them into 1) persistence of response during a period of non-availability of the drug, 2) motivation for WIN 55,212-2 with a progressive ratio, and 3) compulsivity when the reward is associated with a punishment such as an electric foot-shock, in agreement with the Diagnostic and Statistical Manual of Mental Disorders 5th edition (DSM-5). [...]
2023 - 10.3389/fphar.2023.1143365
Frontiers in Pharmacology, Vol. 14 (march 2023)
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17 p, 4.4 MB |
Genetic Adaptation and Acquisition of Macrolide Resistance in spp. during Persistent Respiratory Tract Colonization in Chronic Obstructive Pulmonary Disease (COPD) Patients Receiving Long-Term Azithromycin Treatment
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Carrera-Salinas, Anna (Hospital Universitari de Bellvitge) ;
González-Díaz, Aida (Hospital Universitari de Bellvitge) ;
Ehrlich, Rachel L. (Drexel University College of Medicine) ;
Berbel, Dàmaris (Hospital Universitari de Bellvitge) ;
Tubau, Fe (Hospital Universitari de Bellvitge) ;
Pomares, Xavier (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Garmendia, Junkal (CSIC-Gobierno de Navarra) ;
Domínguez, M. Ángeles (Universitat de Barcelona) ;
Ardanuy, Carmen (Hospital Universitari de Bellvitge) ;
Huertas, Daniel (Hospital Residència Sant Camil) ;
Marín, Alicia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Montón, Conchita (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Mell, Joshua Chang (Drexel University College of Medicine) ;
Santos, Salud (Hospital Universitari de Bellvitge) ;
Marti, Sara (Hospital Universitari de Bellvitge) ;
Universitat Autònoma de Barcelona
Patients with chronic obstructive pulmonary disease (COPD) benefit from the immunomodulatory effect of azithromycin, but long-term administration may alter colonizing bacteria. Our goal was to identify changes in and during azithromycin treatment. [...]
2022 - 10.1128/spectrum.03860-22
Microbiology Spectrum, Vol. 11 (december 2022)
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9.
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8 p, 1.1 MB |
Analysis of the Adherence and Safety of Second Oral Glucose-Lowering Therapy in Routine Practice From the Mediterranean Area : A Retrospective Cohort Study
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Vlacho, Bogdan (Institut d'Investigació Biomèdica Sant Pau) ;
Mata-Cases, M. (Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas) ;
Mundet-Tudurí, Xavier (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Vallès-Callol, J.A. (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Real, J. (Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas) ;
Farre, Magi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Cos Claramunt, Francesc Xavier (Institut Català de la Salut) ;
Khunti, K. (Diabetes Research Centre. College of Life Sciences. University of Leicester) ;
Mauricio Puente, Dídac (Institut d'Investigació Biomèdica Sant Pau) ;
Franch-Nadal, J. (Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas)
The aims of our study was compare adherence measured by the medical possession ratio (MPR), time until discontinuation and describe adverse events after adding a DPP-4i, SGLT-2i, or sulfonylureas (SU) to metformin in a primary care population with insufficient glycemic control. [...]
2021 - 10.3389/fendo.2021.708372
Frontiers in Endocrinology, Vol. 12 (July 2021) , p. 708372
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22 p, 1.8 MB |
Topological Data Analysis and its usefulness for precision medicine studies
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Iniesta, Raquel (King's College London. Institute of Psychiatry, Psychology & Neuroscience) ;
Carr, Ewan (King's College London. Institute of Psychiatry, Psychology & Neuroscience) ;
Carrière, Mathieu (Inria Sophia-Antipolis, DataShape Team, Biot, France) ;
Yerolemou, Naya (The University of Oxford and The Alan Turing Institute) ;
Michel, Bertrand (Ecole Centrale de Nantes, Laboratoire de Mathématiques Jean Leray - Unité mixte de recherche Centre National de la Recherche Scientifique) ;
Chazal, Frédéric (Inria Saclay - Ile-de-France)
Precision medicine allows the extraction of information from complex datasets to facilitate clinical decision-making at the individual level. Topological Data Analysis (TDA) offers promising tools that complement current analytical methods in precision medicine studies. [...]
2022 - 10.2436/20.8080.02.120
SORT : statistics and operations research transactions, Vol. 46 Núm. 1 (2022) , p. 115-136 (Articles)
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