Resultats globals: 3 registres trobats en 0.02 segons.
Articles, 3 registres trobats
Articles 3 registres trobats  
1.
8 p, 735.4 KB The prostaglandin D receptor 2 pathway in asthma : a key player in airway inflammation / Domingo, Christian (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Palomares, Oscar (Complutense University of Madrid. Department of Biochemistry and Molecular Biology) ; Sandham, David A. (Novartis Institutes for Biomedical Research) ; Erpenbeck, Veit J. (Novartis Pharma) ; Altman, Pablo (Novartis Pharmaceuticals Corporation (Estats Units d'Amèrica)) ; Universitat Autònoma de Barcelona
Asthma is characterised by chronic airway inflammation, airway obstruction and hyper-responsiveness. The inflammatory cascade in asthma comprises a complex interplay of genetic factors, the airway epithelium, and dysregulation of the immune response. [...]
2018 - 10.1186/s12931-018-0893-x
Respiratory Research, Vol. 19 (september 2018)  
2.
17 p, 1.6 MB In Vitro and In Vivo Validation of EP2-Receptor Agonism to Selectively Achieve Inhibition of Mast Cell Activity / Plaza, Judith (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Torres Blanch, Rosa (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Urbano, Adrián (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Picado, César (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Mora Pérez, Fernando de (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia)
Agonism of the prostaglandin E2 receptor, E-prostanoid receptor 2 (EP2), may represent an alternative protective mechanism in mast cell (MC)-mediated diseases. Previous studies have suggested that activation of the MC EP2 receptor prevents pathological changes in the murine models of allergic asthma. [...]
2020 - 10.4168/aair.2020.12.4.712
Allergy, Asthma & Immunology Research, Vol. 12 (april 2020) , p. 712-728  
3.
9 p, 1.4 MB Prostaglandin E2 Prevents Hyperosmolar-Induced Human Mast Cell Activation through Prostanoid Receptors EP2 and EP4 / Torres Atencio, Ivonne Marisol (Universidad de Panamá. Facultad de Medicina) ; Ainsua-Enrich, Erola (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Mora Pérez, Fernando de (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Picado Valles, César (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Martín Castillo, Margarita (Institut d'Investigacions Biomèdiques August Pi i Sunyer)
Background: Mast cells play a critical role in allergic and inflammatory diseases, including exercise-induced bronchoconstriction (EIB) in asthma. The mechanism underlying EIB is probably related to increased airway fluid osmolarity that activates mast cells to the release inflammatory mediators. [...]
2014 - 10.1371/journal.pone.0110870
PloS one, Vol. 9, Issue 10 (October 2014) , p.e110870  

Us interessa rebre alertes sobre nous resultats d'aquesta cerca?
Definiu una alerta personal via correu electrònic o subscribiu-vos al canal RSS.