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Resultats globals: 7 registres trobats en 0.02 segons.
Articles, 6 registres trobats
Documents de recerca, 1 registres trobats
Articles 6 registres trobats  
1.
19 p, 9.2 MB ERK5 Is a Major Determinant of Chemical Sarcomagenesis : Implications in Human Pathology / Arconada-Luque, Elena (Centro Regional de Investigaciones Biomédicas) ; Jiménez-Suarez, Jaime (Centro Regional de Investigaciones Biomédicas) ; Pascual-Serra, Raquel (Centro Regional de Investigaciones Biomédicas) ; Nam-Cha, Syong Hyun (Complejo Hospitalario Universitario de Albacete) ; Moliné, Teresa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Cimas, Francisco J. (Universidad de Castilla-La Mancha) ; Fliquete, Germán (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Ortega-Muelas, Marta (Centro Regional de Investigaciones Biomédicas) ; Roche, Olga (Universidad de Castilla-La Mancha) ; Fernández-Aroca, Diego M. (Centro Regional de Investigaciones Biomédicas) ; Muñoz Velasco, Raúl (Instituto de Investigación Sanitaria Hospital 12 de Octubre (i+12)) ; García-Flores, Natalia (Centro Regional de Investigaciones Biomédicas) ; Garnés-García, Cristina (Centro Regional de Investigaciones Biomédicas) ; Sánchez-Fdez, Adrián (Centro de Investigación Biomédica en Red de Cáncer) ; Matilla-Almazán, Sofía (Centro de Investigación Biomédica en Red de Cáncer) ; Sánchez-Arévalo Lobo, Víctor J. (Instituto de Investigación Sanitaria Hospital 12 de Octubre (i+12)) ; Hernandez-Losa, Javier (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Belandia, Borja (Instituto de Investigaciones Biomédicas 'Alberto Sols' (CSIC-UAM)) ; Pandiella, Atanasio (Centro de Investigación Biomédica en Red de Cáncer) ; Esparís-Ogando, Azucena (Centro de Investigación Biomédica en Red de Cáncer) ; Ramón y Cajal, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; del Peso, Luis (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ; Sánchez-Prieto, Ricardo (Instituto de Investigaciones Biomédicas 'Alberto Sols') ; Ruiz-Hidalgo, María José (Universidad de Castilla-La Mancha) ; Universitat Autònoma de Barcelona
Sarcoma is a heterogeneous group of tumors poorly studied with few therapeutic opportunities. Interestingly, the role of MAPKs still remains unclear in sarcomatous pathology. Here, we describe for the first time the critical role of ERK5 in the biology of soft tissue sarcoma by using in vitro and in vivo approaches in a murine experimental model of chemical sarcomagenesis. [...]
2022 - 10.3390/cancers14143509
Cancers, Vol. 14 (july 2022)  
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2.
13 p, 1.6 MB MicroRNA-101 is repressed by EZH2 and its restoration inhibits tumorigenic features in embryonal rhabdomyosarcoma / Vella, Serena (Ospedale Pediatrico Bambino Gesù) ; Pomella, Silvia (Istituto Dermopatico dell'Immacolata) ; Leoncini, Pier Paolo (Ospedale Pediatrico Bambino Gesù) ; Colletti, Marta (Ospedale Pediatrico Bambino Gesù) ; Conti, Beatrice (Ospedale Pediatrico Bambino Gesù) ; Marquez, Victor E. (Frederick National Laboratory for Cancer Research) ; Strillacci, Antonio (University of Bologna) ; Roma, Josep (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Gallego, Soledad (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Milano, Giuseppe M. (Ospedale Pediatrico Bambino Gesù) ; Capogrossi, Maurizio C. (Istituto Dermopatico dell'Immacolata) ; Bertaina, Alice (Ospedale Pediatrico Bambino Gesù) ; Ciarapica, Roberta (Istituto Dermopatico dell'Immacolata) ; Rota, Rossella (Laboratory of Angiogenesis, Ospedale Pediatrico Bambino Gesù) ; Universitat Autònoma de Barcelona
Rhabdomyosarcoma (RMS) is a pediatric soft tissue sarcoma arising from myogenic precursors that have lost their capability to differentiate into skeletal muscle. The polycomb-group protein EZH2 is a Lys27 histone H3 methyltransferase that regulates the balance between cell proliferation and differentiation by epigenetically silencing muscle-specific genes. [...]
2015 - 10.1186/s13148-015-0107-z
Clinical Epigenetics, Vol. 7 (august 2015)  
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3.
12 p, 1.7 MB Ligand-dependent Hedgehog pathway activation in Rhabdomyosarcoma : the oncogenic role of the ligands / Almazán-Moga, Anna (Hospital Universitari Vall d'Hebron) ; Zarzosa, Patricia (Hospital Universitari Vall d'Hebron) ; Molist, C. (Hospital Universitari Vall d'Hebron) ; Velasco, Pablo (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ; Pyczek, J. (Institute of Human Genetics, University of Goettingen) ; Simon-Keller, K. (Institute of Pathology, University Medical Centre Mannheim, University of Heidelberg) ; Giralt, Irina (Hospital Universitari Vall d'Hebron) ; Vidal, I (Hospital Universitari Vall d'Hebron) ; Navarro, N. (Hospital Universitari Vall d'Hebron) ; Segura, M. F. (Hospital Universitari Vall d'Hebron) ; Soriano, Aroa (Hospital Universitari Vall d'Hebron) ; Navarro, Susanna (Universitat de València. Departament de Patologia) ; Tirado, O. M. (Institut d'Investigació Biomèdica de Bellvitge) ; Ferreres Piñas, Joan Carles (Hospital Universitari Vall d'Hebron) ; Santamaria, A. (Hospital Universitari Vall d'Hebron) ; Rota, R. (Ospedale Pediatrico Bambino Gesù, IRCCS) ; Hahn, H. (Institute of Human Genetics, University of Goettingen) ; Sánchez de Toledo, J.. (Hospital Universitari Vall d'Hebron) ; Roma, Josep (Hospital Universitari Vall d'Hebron) ; Gallego, Soledad (Hospital Universitari Vall d'Hebron)
Rhabdomyosarcoma (RMS) is the most common type of soft tissue sarcoma in children. The Hedgehog (HH) pathway is known to develop an oncogenic role in RMS. However, the molecular mechanism that drives activation of the pathway in RMS is not well understood. [...]
2017 - 10.1038/bjc.2017.305
British Journal of Cancer, Vol. 117 (09 2017) , p. 1314-1325  
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4.
14 p, 3.4 MB Hedgehog Pathway Inhibition Hampers Sphere and Holoclone Formation in Rhabdomyosarcoma / Almazán-Moga, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Zarzosa, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Vidal, Isaac (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Molist, Carla (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Giralt, Irina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Navarro Barea, Natalia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Soriano, Aroa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Segura, Miguel F. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Alfranca, Arantza (Instituto de Salud Carlos III) ; Garcia-Castro, Javier (Instituto de Salud Carlos III) ; Sánchez de Toledo, José (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ; Roma, Josep (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Gallego, Soledad (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública)
Rhabdomyosarcoma (RMS) is the most common type of soft tissue sarcoma in children and can be divided into two main subtypes: embryonal (eRMS) and alveolar (aRMS). Among the cellular heterogeneity of tumors, the existence of a small fraction of cells called cancer stem cells (CSC), thought to be responsible for the onset and propagation of cancer, has been demonstrated in some neoplasia. [...]
2017 - 10.1155/2017/7507380
Stem Cells International, Vol. 2017 (january 2017)  
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5.
10 p, 2.0 MB Notch-mediated induction of N-cadherin and α 9-integrin confers higher invasive phenotype on rhabdomyosarcoma cells / Masià, A. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Almazán-Moga, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Velasco, P. (Hospital Universitari Vall d'Hebron) ; Reventós, J. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Torán, N. (Hospital Universitari Vall d'Hebron) ; Sánchez de Toledo, J.. (Hospital Universitari Vall d'Hebron) ; Roma, Josep (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Gallego, Soledad (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Rhabdomyosarcoma (RMS) is the commonest type of soft-tissue sarcoma in children. Patients with metastatic RMS continue to have very poor prognosis. Recently, several works have demonstrated a connection between Notch pathway activation and the regulation of cell motility and invasiveness. [...]
2012 - 10.1038/bjc.2012.411
British Journal of Cancer, Vol. 107 (09 2012) , p. 1374-1383  
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6.
12 p, 1.5 MB DNA methylation dynamics in muscle development and disease / Carrió Gaspar, Elvira (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Suelves Esteban, Mònica (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer)
DNA methylation is an essential epigenetic modification for mammalian development and is crucial for the establishment and maintenance of cellular identity. Traditionally, DNA methylation has been considered as a permanent repressive epigenetic mark. [...]
2015 - 10.3389/fnagi.2015.00019
Frontiers in aging neuroscience, Vol. 7 Núm. 19 (2015)  
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Documents de recerca 1 registres trobats  
1.
1 p, 396.2 KB Overview of the rhabdomyosarcoma : from a molecular study to a therapeutic design / Lara Cerrillo, Sandra ; Itarte, Emilio, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2014
Grau en Biotecnologia [815]  
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