Home > Search Results: Morgan, Philip G.
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Articles, 2 records found
Articles 2 records found  
1.
5 p, 216.6 KB Altered Anesthetic Sensitivity of Mice Lacking Ndufs4, a Subunit of Mitochondrial Complex I / Quintana Romero, Albert (University of Washington. Howard Hughes Medical Institute and Department of Biochemistry) ; Morgan, Philip G. (University of Washington. Department of Anesthesiology and Pain Medicine) ; Kruse, Shane E. (University of Washington. Howard Hughes Medical Institute and Department of Biochemistry) ; Sedensky, Margaret M. (Seattle Children's Research Institute)
Anesthetics are in routine use, yet the mechanisms underlying their function are incompletely understood. Studies in vitro demonstrate that both GABAA and NMDA receptors are modulated by anesthetics, but whole animal models have not supported the role of these receptors as sole effectors of general anesthesia. [...]
2012 - 10.1371/journal.pone.0042904
PloS one, Vol. 7, Num. 8 (2012) , p. e42904  
Detailed record - Creative Commons
2.
26 p, 2.1 MB Glutamatergic neurotransmission links sensitivity to volatile anesthetics with mitochondrial function / Zimin, Pavel I. (Seattle Children's Research Institute. Center for Developmental Therapeutics (Seattle, Estats Units d'Amèrica)) ; Woods, Christian B. (Seattle Children's Research Institute. Center for Developmental Therapeutics (Seattle, Estats Units d'Amèrica)) ; Quintana Romero, Albert (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Ramirez, Jan-Marino (Seattle Children's Research Institute. Center for Integrative Brain Research (Seattle, Estats Units d'Amèrica)) ; Morgan, Philip G. (Seattle Children's Research Institute. Center for Developmental Therapeutics (Seattle, Estats Units d'Amèrica)) ; Sendensky, Margaret M. (Seattle Children's Research Institute. Center for Developmental Therapeutics (Seattle, Estats Units d'Amèrica))
An enigma of modern medicine has persisted for over 150 years. The mechanisms by which volatile anesthetics (VAs) produce their effects (loss of consciousness, analgesia, amnesia, and immobility) remain an unsolved mystery. [...]
2016 - 10.1016/j.cub.2016.06.020
Current biology, Vol. 26, Issue 16 (August 2016) , p. 2194-2201  
Detailed record - Creative Commons

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