2026-04-20
14:12 |
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11 p, 1.9 MB |
Histamine plasma levels from dietary histidine/histamine intake correlate with CGRP in trigeminal tissues
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Mora Pérez, Fernando de (Universidad Autónoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Dux, Mária (University of Szeged) ;
Vogler, Birgit (Friedrich-Alexander-University Erlangen-Nürnberg) ;
Kuhn, Annette (Friedrich-Alexander-University Erlangen-Nürnberg) ;
Schramm, Jana (Friedrich-Alexander-University Erlangen-Nürnberg) ;
Messlinger, Karl (Friedrich-Alexander-University Erlangen-Nürnberg)
Trigeminal afferents innervating the meninges are likely involved in the generation of headaches and migraine. A major proportion of these afferents can release calcitonin gene-related peptide (CGRP) upon stimulation. [...]
2025 -  10.1186/s10194-025-02178-x
Journal of headache and pain, Vol. 26 (November 2025) , art. 258
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2026-04-20
14:12 |
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2026-04-20
14:12 |
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9 p, 328.5 KB |
The impact of thyroid disorders on the gut microbiome : emerging mechanisms and clinical relevance
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Silva, Isabela Busto (Serviço de Endocrinologia e Metabologia do Hospital de Clínicas da Universidade Federal do Paraná (Curitiba, Brasil)) ;
Puig Domingo, Manuel (Institut Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
The thyroid-gut axis represents a dynamic interaction between the intestinal microbiota and thyroid function, with growing evidence linking gut dysbiosis to thyroid diseases. The gut microbiome, comprising over 100 trillion microorganisms, influences immune modulation, iodine metabolism, and thyroid hormone regulation. [...]
2025 - 10.20945/2359-4292-2025-0075
Archives of Endocrinology and Metabolism, Vol. 70 (November 2025) , art. e250075
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2026-04-21
10:12 |
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11 p, 1.1 MB |
Ambulatory bilateral groin hernia repair : open preperitoneal versus laparoscopic outcomes
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Gómez-Jurado, Maria José (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Verdaguer-Tremolosa, Mireia (Hospital Universitari Vall d'Hebron) ;
Rodrigues-Gonçalves, Víctor (Hospital Universitari Vall d'Hebron) ;
Martínez-López, Pilar (Hospital Universitari Vall d'Hebron) ;
Martínez-López, María (Hospital Universitari Vall d'Hebron) ;
Pera, Meritxell (Hospital Universitari Vall d'Hebron) ;
Dalmau, Mar (Hospital Universitari Vall d'Hebron) ;
López Cano, Manuel (Hospital Universitari Vall d'Hebron)
To evaluate short and long-term outcomes of bilateral groin hernia (BGH) repair using an open preperitoneal approach (OPA) compared to minimally invasive surgery (MIS) in ambulatory surgery. A retrospective cohort study was conducted including patients undergoing ambulatory BGH repair between 2010 and 2018 at Vall d'Hebron University Hospital (Barcelona) using either OPA (a modified Wantz technique) or MIS [transabdominal preperitoneal (TAPP) or totally extraperitoneal (TEP)]. [...]
2025 - 10.1007/s10029-025-03523-4
Hernia, Vol. 30 (November 2025) , art. 17
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2026-04-21
11:12 |
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8 p, 3.4 MB |
Emergence of Vibrio and related genera infections in a hotspot of climate risks, southern Spain, 2010-2023
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Jurado-Tarifa, Estefanía (Universidad de Cádiz) ;
Martínez-Urtaza, Jaime (Universitat Autònoma de Barcelona) ;
Tapia-Poza, Sandra (Instituto de Investigación e Innovación en Ciencias Biomédicas de la Provincia de Cádiz) ;
Guerrero-Lozano, Inmaculada (Universidad de Cádiz) ;
Trujillo-Soto, Teresa (Hospital Universitaria Puerta del Mar (Càdis, Andalusia)) ;
Galán-Sánchez, Fátima (Hospital Universitaria Puerta del Mar (Càdis, Andalusia)) ;
Sánchez-Calvo, Juan M. (Hospital Universitari Jerez) ;
Triñanes-Fernández, Joaquín A. (Universitat Santiago de Compostela) ;
Rodríguez-Iglesias, Manuel A. (Universidad de Cádiz)
Vibrio has emerged as one of responsive pathogens to the conditions imposed by global warming, with an increasing impact in northern Europe. The epidemiological significance of these pathogens remains undetermined in the south of Europe. [...]
2025 - 10.1016/j.onehlt.2025.101267
One Health, Vol. 21 (November 2025) , art. 101267
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2026-04-21
09:12 |
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9 p, 872.3 KB |
Robot-Assisted Salvage Prostatectomy : External Validation of the EAU Selection Criteria and Identification of the Optimal Candidate: A Junior ERUS/YAU Collaborative Study
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Wenzel, Mike (Goethe University Hospital Frankfurt) ;
Würnschimmel, Christoph (Luzerner Kantonsspital (Suïssa)) ;
Nathan, Arjun (University College London Hospitals NHS Foundation Trust) ;
Moschovas, Marcio Covas (AdventHealth Global Robotics Institute) ;
Wagner, Christian (Prostate Center Northwest, St. Antonius-Hospital) ;
Calleris, Giorgio (University of Turin and Città della Salute e della Scienza) ;
Di Maida, Fabrizio (University of Florence) ;
Rivas, Juan Gomez (Hospital Clínico San Carlos (Madrid)) ;
Bravi, Carlo Andrea (ORSI Academy) ;
Groote, Ruben De (ORSI Academy) ;
Piramide, Federico (University of Turin) ;
Turri, Filippo (University of Milan) ;
Kowalczyk, Keith (MedStar Georgetown University Hospital) ;
Sharma, Gopal (Medanta - The Medicity) ;
Andras, Iulia (Iuliu Hatieganu University of Medicine and Pharmacy) ;
Lambert, Edward (Universitair Ziekenhuis Gent) ;
Liakos, Nikolaos (Medical Centre of the University of Freiburg) ;
Darlington, Danny (Royal Surrey County Hospital) ;
Paciotti, Marco (Humanitas Research Hospital - IRCCS) ;
Sorce, Gabriele (Istituto di Ricovero e Cura A Carattere Scientifico (IRCCS)) ;
Mandel, Philipp (Goethe University Hospital Frankfurt) ;
Galfano, Antonio (ASST Grande Ospedale Metropolitano Niguarda) ;
Nathan, Senthil (University College London Hospitals NHS Foundation Trust) ;
Marra, Giancarlo (University of Turin and Città della Salute e della Scienza) ;
Dell'Oglio, Paolo (ASST Grande Ospedale Metropolitano Niguarda) ;
Mottrie, Alexandre (ORSI Academy) ;
Chun, Felix K. H. (Goethe University Hospital Frankfurt) ;
Patel, Vipul (AdventHealth Global Robotics Institute) ;
Breda, Alberto (Institut de Recerca Sant Pau) ;
Larcher, Alessandro (Istituto di Ricovero e Cura A Carattere Scientifico (IRCCS)) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Background: EAU guidelines recommend salvage radical prostatectomy (sRP) only in highly selected patients with recurrent prostate cancer in experienced centers. Methods: The Junior ERUS/Young Academic Urologist Working Group on Robot-Assisted Surgery conducted a multicentric project to investigate biochemical recurrence-free (BCR), metastases-free (MFS), and overall survival (OS) outcomes in robotic sRP patients stratified according to EAU criteria. [...]
2025 - 10.1002/pros.70048
The Prostate, Vol. 86 (September 2025) , p. 3-11
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2026-04-21
09:12 |
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9 p, 1.6 MB |
SynaptopathyDB integrates synaptic proteomes, genetic and phenotypic data to advance research on nervous system disorders
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Bayés, Àlex (Institut de Recerca Sant Pau) ;
Grant, Seth G. N. (University of Edinburgh) ;
Sorokina, Oksana (University of Edinburgh) ;
Dominic, Digin (University of Edinburgh) ;
Armstrong, J. Douglas (University of Edinburgh) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Synaptic dysfunction resulting from pathogenic variants in genes encoding synaptic proteins is a major contributor to brain and behavioural disorders, collectively termed synaptopathies. To facilitate research into the genetic basis and clinical manifestations of synaptopathy we have created SynaptopathyDB, an online resource that integrates data from 64 mammalian synapse proteomic studies and multiple genetic and phenotypic resources (). [...]
2025 - 10.1038/s41598-025-26969-z
Scientific reports, Vol. 15 (December 2025) , art. 42986
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2026-04-21
09:12 |
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10 p, 1000.3 KB |
Barriers to discontinuing benzodiazepine receptor agonists in older adults : a survey of older adults across Europe
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Shapoval, Vladyslav (Université catholique de Louvain (1970- )) ;
de Saint Hubert, Marie (Université catholique de Louvain (1970- )) ;
Aubert, Carole Elodie (University of Bern) ;
Mooser, Blandine (University of Bern) ;
Tsoutsi, Vagioula (National & Kapodistrian University of Athens) ;
Dikeos, Dimitris (National & Kapodistrian University of Athens) ;
Wichniak, Adam (Sleep Medicine Centre, Poland) ;
Gustavsson, Katarzyna (Sleep Medicine Centre, Poland) ;
Wyller, Torgeir Bruun (University of Oslo) ;
Callegari, Enrico (Oslo University Hospital) ;
Grimshaw, Jeremy (University of Ottawa) ;
Presseau, Justin (University of Ottawa) ;
Henrard, Séverine (Université catholique de Louvain (1970- )) ;
Spinewine, Anne (Université catholique de Louvain (1970- )) ;
Pétein, Catherine (Université catholique de Louvain (1970- )) ;
Viaud, Claire (CHU UCL Namur, Belgium) ;
Adda, Tokandji (Université catholique de Louvain (1970- )) ;
Fernández Maldonado, Laura (Universitat Autònoma de Barcelona. Fundació Salut i Envelliment) ;
Pérez-Castejón, Joan-Manuel (Badalona Serveis Assistencials) ;
Patey, Andrea (IWK Health Centre, Halifax, Nova Scotia, Canada) ;
Corachan, Sabine (Université catholique de Louvain (1970- ))
Various factors hinder older adults from discontinuing benzodiazepine receptor agonists (BZRAs). Identifying and prioritising these barriers is essential for designing effective interventions to discontinue BZRAs. [...]
2025 - 10.1093/ageing/afaf342
Age and Ageing, Vol. 54 (December 2025) , art. afaf342
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2026-04-20
17:12 |
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20 p, 3.9 MB |
Dialister -driven succinate accumulation is associated with disease activity and postoperative recurrence in Crohn's disease
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Boronat-Toscano, Albert (Hospital Universitari Joan XXIII de Tarragona. Institut d'Investigació Sanitària Pere Virgili) ;
Queipo-Ortuño, Maribel (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia)) ;
Monfort-Ferré, Diandra (Hospital Universitari Joan XXIII de Tarragona. Institut d'Investigació Sanitària Pere Virgili) ;
Suau, Roger (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Vañó-Segarra, Irene (Hospital Universitari Joan XXIII de Tarragona. Institut d'Investigació Sanitària Pere Virgili) ;
Valldosera, Gemma (Hospital Universitari Joan XXIII de Tarragona. Institut d'Investigació Sanitària Pere Virgili) ;
Cepero, Claudia (Hospital Universitari Joan XXIII de Tarragona. Institut d'Investigació Sanitària Pere Virgili) ;
Astiarraga, Brenno (Hospital Universitari Joan XXIII de Tarragona. Institut d'Investigació Sanitària Pere Virgili) ;
Clua-Ferré, Laura (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Plaza-Andrade, Isaac (Hospital Clinico Universitario Virgen de la Victoria (Màlaga)) ;
Aranega-Martín, Lucía (Hospital Clinico Universitario Virgen de la Victoria (Màlaga)) ;
Cabrinety, Lidia (Hospital Universitari Joan XXIII de Tarragona. Institut d'Investigació Sanitària Pere Virgili) ;
Abadia de Barbarà, Carme (Hospital Universitari Joan XXIII de Tarragona. Institut d'Investigació Sanitària Pere Virgili) ;
Castellano, Daniel (Hospital Clinico Universitario Virgen de la Victoria (Màlaga)) ;
Moliné, Alicia (Hospital Universitari Joan XXIII de Tarragona. Institut d'Investigació Sanitària Pere Virgili) ;
Caro, Aleidis (Hospital Universitari Joan XXIII de Tarragona. Institut d'Investigació Sanitària Pere Virgili) ;
Domènech, Eugeni (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Sánchez-Herrero, Jose Francisco (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Benaiges-Fernandez, Robert (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Fernández-Veledo, Sonia (Hospital Universitari Joan XXIII de Tarragona. Institut d'Investigació Sanitària Pere Virgili) ;
Vendrell, Joan (Hospital Universitari Joan XXIII de Tarragona. Institut d'Investigació Sanitària Pere Virgili) ;
Sumoy, Lauro (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Manyé, Josep (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Menacho, Margarita (Hospital Universitari Joan XXIII de Tarragona. Institut d'Investigació Sanitària Pere Virgili) ;
Serena, Carolina (Hospital Universitari Joan XXIII de Tarragona. Institut d'Investigació Sanitària Pere Virgili)
Succinate, a metabolite produced by both the gut microbiota and the host, has emerged as a key player in chronic inflammation. In patients with Crohn's disease (CD), increased succinate in the intestinal lumen correlates with both dysbiosis and greater disease activity. [...]
2025 - 10.3748/wjg.v31.i45.112618
World Journal of Gastroenterology, Vol. 31, Num. 45 (December 2025) , art. 112618
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2026-04-20
16:12 |
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20 p, 4.1 MB |
Characterization of Infarct Size and Remodeling Using CMR and PET in Mice Models of Reperfused and Non-Reperfused Myocardial Infarction
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Gavara Doñate, Jose (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Molina-Garcia, Tamara (Universitat de València) ;
Ezzeddin, Mustafa (Universitat de València) ;
Diaz, Ana (Universitat de València) ;
Perez-Solé, Nerea (Centro de Investigación Biomédica en Red-Cardiovascular (Madrid)) ;
Ortega, Maria (INCLIVA Biomedical Research Institute) ;
Marcos-Garces, Victor (Hospital Clínic Universitari (València)) ;
de Dios, Elena (Centro de Investigación Biomédica en Red-Cardiovascular (Madrid)) ;
Bayés-Genís, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Ruiz-Sauri, Amparo (Universitat de València) ;
Rios-Navarro, Cesar (Universitat de València) ;
Bodi, Vicente (Hospital Clínic Universitari (València))
Background/Objectives : Unlike post-mortem histopathology, cardiovascular magnetic resonance (CMR) and positron emission tomography (PET) enable longitudinal assessment of structural, functional, and metabolic alterations in preclinical myocardial infarction models. [...]
2025 - 10.3390/diagnostics15232960
Diagnostics, Vol. 15, Num. 23 (November 2025) , art. 2960
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