Institut Català de Paleontologia Miquel Crusafont (ICP)

El ICP es un centro de investigación público de la institución CERCA (Centros de Investigación de Cataluña) establecido como una fundación sin ánimo de lucro dotada de fondos públicos y que tiene como patrones la Generalitat de Catalunya y la Universitat Autònoma de Barcelona (UAB). La misión del ICP consiste en llevar a cabo investigación en paleontología de vertebrados y humana al más alto nivel internacional, así como promover la conservación y difusión del patrimonio paleontológico de Cataluña. Este portal web contiene la producción científica del ICP, organizada en las siguientes categorías:

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2020-11-16
08:36
A new dryopithecine mandibular fragment from the middle Miocene of Abocador de Can Mata and the taxonomic status of 'Sivapithecus' occidentalis from Can Vila (Vallès-Penedès Basin, NE Iberian Peninsula) / Alba, David M. (Institut Català de Paleontologia Miquel Crusafont) ; Fortuny Terricabras, Josep (Institut Català de Paleontologia Miquel Crusafont) ; Robles Giménez, Josep Maria (Institut Català de Paleontologia Miquel Crusafont) ; Bernardini, Federico (Museo Storico della Fisica e Centro di Studi e Ricerche 'Enrico Fermi' (Italy)) ; Pérez de los Ríos, Miriam (Universidad de Chile. Departamento de Antropología (Chile)) ; Tuniz, Claudio (University of Wollongong. Center for Archaeological Science (Australia)) ; Moyà Solà, Salvador (Institut Català de Paleontologia Miquel Crusafont) ; Zanolli, Clément (Centre National de la Recherche Scientifique. Université de Bordeaux. Laboratoire PACEA (France))
2020 - 10.1016/j.jhevol.2020.102790
Journal of human evolution, Vol. 145 (August 2020) , art. 102790  
2020-08-03
04:07
22 p, 2.7 MB Modularity and heterochrony in the evolution of the ceratopsian dinosaur frill / Prieto-Márquez, Albert (Institut Català de Paleontologia Miquel Crusafont) ; Garcia-Porta, Joan (Centre de Recerca Ecològica i d'Aplicacions Forestals) ; Joshi, Shantanu H. (University of California, Los Angeles) ; Norell, Mark (American Museum of Natural History) ; Makovicky, Peter J. (University of Minnesota)
The fossil record provides compelling examples of heterochrony at macroevolutionary scales such as the peramorphic giant antlers of the Irish elk. Heterochrony has also been invoked in the evolution of the distinctive cranial frill of ceratopsian dinosaurs such as Triceratops. [...]
2020 - 10.1002/ece3.6361
Ecology and evolution, Vol. 10, Issue 13 (July 2020) , p. 6288-6309  
2020-08-03
04:07
11 p, 571.9 KB Multiple genomic events altering Hominin SIGLEC biology and innate immunity predated the common ancestor of humans and archaic Hominins / Khan, Naazneen (University of California. Glycobiology Research and Training Center. Department of Medicine (USA)) ; de Manuel, Marc (Universitat Pompeu Fabara. Institut de Biologia Evolutiva) ; Peyregne, Stephane (Max Planck Institute for Evolutionary Anthropology. Department of Evolutionary Genetics (Germany)) ; Do, Raymond (University of California. Glycobiology Research and Training Center. Department of Medicine (USA)) ; Prufer, Kay (Max Planck Institute for Evolutionary Anthropology. Department of Evolutionary Genetics (Germany)) ; Marquès i Bonet, Tomàs, 1975- (Institut Català de Paleontologia Miquel Crusafont) ; Varki, Nissi (University of California. Glycobiology Research and Training Center. Department of Medicine (USA)) ; Gagneux, Pascal (University of California. Glycobiology Research and Training Center. Department of Medicine (USA)) ; Varki, Ajit (University of California. Glycobiology Research and Training Center. Department of Medicine (USA))
Human-specific pseudogenization of the CMAH gene eliminated the mammalian sialic acid (Sia) Neu5Gc (generating an excess of its precursor Neu5Ac), thus changing ubiquitous cell surface "self-associated molecular patterns" that modulate innate immunity via engagement of CD33-related-Siglec receptors. [...]
2020 - 10.1093/gbe/evaa125
Genome biology and evolution, Vol. 12, Issue 7 (July 2020) , p. 1040-1050  
2020-07-13
08:02
35 p, 2.6 MB Copy number variants and fixed duplications among 198 rhesus macaques (Macaca mulatta) / Brasó-Vives, Marina (Laboratoire de Biométrie et Biologie Évolutive UMR 5558, Université de Lyon, Université Lyon 1, CNRS, Villeurbanne, France) ; Povolotskaya, Inna S. (Veltischev Research and Clinical Institute for Pediatrics of the Pirogov Russian National Research Medical University, Moscow, Russia) ; Hartasánchez, Diego A. (Institut de Biologia Evolutiva (CSIC-Universitat Pompeu Fabra), Parc de Recerca Biomèdica de Barcelona, Barcelona, Catalonia, Spain) ; Farré, Xavier (Institut de Biologia Evolutiva (CSIC-Universitat Pompeu Fabra), Parc de Recerca Biomèdica de Barcelona, Barcelona, Catalonia, Spain) ; Fernández Callejo, Marcos (National Centre for Genomic Analysis-Centre for Genomic Regulation, Barcelona Institute of Science and Technology, Barcelona, Catalonia, Spain) ; Raveendran, Muthuswamy (Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America) ; Harris, R. Alan (Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America) ; Rosene, Douglas L. (Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, Massachusetts, United States of America) ; Lorente-Galdos, Belen (Department of Neuroscience, Yale School of Medicine, New Haven, Connecticut, United States of America) ; Navarro, A, 1969- (Institució Catalana de Recerca i Estudis Avançats, Barcelona, Catalonia, Spain) ; Marquès i Bonet, Tomàs, 1975- (Institut Català de Paleontologia Miquel Crusafont) ; Rogers, Jeffrey (Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America) ; Juan, David (Institut de Biologia Evolutiva (CSIC-Universitat Pompeu Fabra), Parc de Recerca Biomèdica de Barcelona, Barcelona, Catalonia, Spain)
The rhesus macaque is an abundant species of Old World monkeys and a valuable model organism for biomedical research due to its close phylogenetic relationship to humans. Copy number variation is one of the main sources of genomic diversity within and between species and a widely recognized cause of inter-individual differences in disease risk. [...]
2020 - 10.1371/journal.pgen.1008742
PLoS Genetics, Vol. 16 (may 2020)  
2020-07-13
08:02
8 p, 2.5 MB The evolutionary history of extinct and living lions / de Manuel, Marc (Universitat Pompeu Fabra. Institut de Biologia Evolutiva) ; Barnett, Ross (University of Copenhagen) ; Sandoval-Velasco, Marcela (University of Copenhagen) ; Yamaguchi, Nobuyuki (University Malaysia Terengganu) ; Garrett Vieira, Filipe (University of Copenhagen) ; Zepeda Mendoza, Marie Lisandra Lisandra (University of Birmingham) ; Liu, Shiping (BGI-Shenzhen) ; Martin, Michael D. (Norwegian University of Science and Technology) ; Sinding, Mikkel-Holger S. (University of Copenhagen) ; Mak, Sarah S. T. (University of Copenhagen) ; Carøe, Christian (University of Copenhagen) ; Liu, Shanlin (BGI-Shenzhen) ; Guo, Chunxue (BGI-Shenzhen) ; Zheng, Jiao (University of Chinese. Academy of Sciences) ; Zazula, Grant (Government of Yukon) ; Baryshnikov, Gennady (Russian Academy of Sciences) ; Eizirik, Eduardo (Instituto Pró-Carnívoros) ; Koepfli, Klaus-Peter (Smithsonian Conservation Biology Institute, National Zoological Park) ; Johnson, Warren E. (Walter Reed Army Institute of Research) ; Antunes, Agostinho (University of Porto) ; Sicheritz-Ponten, Thomas (Asian Institute of Medicine, Science and Technology) ; Gopalakrishnan, Shyam (University of Copenhagen) ; Larson, Greger (University of Oxford) ; Yang, Huanming (James D. Watson Institute of Genome Science) ; O'Brien, Stephen J. (Nova Southeastern University) ; Hansen, Anders J. (University of Copenhagen) ; Zhang, Guojie (Chinese Academy of Sciences) ; Marques-Bonet, Tomas (Institut Català de Paleontologia Miquel Crusafont) ; Gilbert, M. Thomas P. (Norwegian University of Science and Technology)
Lions were once the most globally widespread mammal species, with distinct populations in Africa, Eurasia, and America. We generated a genomic dataset that included 2 extinct Pleistocene cave lions, 12 lions from historically extinct populations in Africa and the Middle East, and 6 modern lions from Africa and India. [...]
2020 - 10.1073/pnas.1919423117
Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, Num. 20 (May 2020) , p. 10927-10934  
2020-07-13
08:02
15 p, 726.6 KB Inference of natural selection from ancient DNA / Dehasque, Marianne (Stockholm University) ; Ávila-Arcos, Maria C. (UNAM Juriquilla) ; Díez, David (Stockholm University) ; Fumagalli, Matteo (Imperial College London) ; Guschanski, Katerina (Uppsala University) ; Lorenzen, Eline (University of Copenhagen) ; Malaspinas, Anna-Sapfo (University of Lausanne. SIB Swiss Institute of Bioinformatics) ; Marques-Bonet, Tomas (Institut Català de Paleontologia Miquel Crusafont) ; Martin, Michael D. (Norwegian University of Science and Technology) ; Murray, Gemma G. R. (University of Cambridge) ; Papadopulos, Alexander S. T. (Bangor University) ; Therkildsen, Nina Overgaard (Cornell University) ; Wegmann, Daniel (Swiss Institute of Bioinformatics) ; Dalén, Love (Swedish Museum of Natural History) ; Foote, Andrew D. (Bangor University)
Evolutionary processes, including selection, can be indirectly inferred based on patterns of genomic variation among contemporary populations or species. However, this often requires unrealistic assumptions of ancestral demography and selective regimes. [...]
2020 - 10.1002/evl3.165
Evolution Letters, Vol. 4, Issue 2 (April 2020) , p. 94-108  
2020-07-06
04:49
13 p, 1.5 MB Plasmodium vivax Malaria viewed through the lens of an eradicated European strain / van Dorp, Lucy (University College London. UCL Genetics Institute (UK)) ; Gelabert Xirinachs, Pere (Universitat Pompeu Fabra. Institut de Biologia Evolutiva) ; Rieux, Adrien (Coopération Internationale en Recherche Agronomique pour le Développement (France)) ; de Manuel, Marc (Universitat Pompeu Fabra. Institut de Biologia Evolutiva) ; de Dios, Toni (Universitat Pompeu Fabra. Institut de Biologia Evolutiva) ; Gopalakrishnan, Shyam (University of Copenhagen. The GLOBE Institute (Denmark)) ; Carøe, Christian (University of Copenhagen. The GLOBE Institute (Denmark)) ; Sandoval Velasco, Marcela (University of Copenhagen. The GLOBE Institute (Denmark)) ; Fregel, Rosa (Universidad de La Laguna. Departamento de Bioquímica, Microbiología, Biología Celular y Genética) ; Olalde, Iñigo (Harvard Medical School. Department of Genetics (USA)) ; Escosa, Raül (Consorci de Polítiques Ambientals de les Terres de l'Ebre) ; Aranda, Carles (Consell Comarcal del Baix Llobregat. Servei de Control de Mosquits) ; Huijben, Silvie (Hospital Clínic-Universitat de Barcelona. ISGlobal Institut de Salut Global de Barcelona) ; Mueller, Ivo (Hospital Clínic-Universitat de Barcelona. ISGlobal Institut de Salut Global de Barcelona) ; Marquès i Bonet, Tomàs, 1975- (Institut Català de Paleontologia Miquel Crusafont) ; Balloux, François (University College London. UCL Genetics Institute (UK)) ; Gilbert, M Thomas P (University of Copenhagen. The GLOBE Institute (Denmark)) ; Lalueza-Fox, Carles (Universitat Pompeu Fabra. Institut de Biologia Evolutiva)
The protozoan Plasmodium vivax is responsible for 42% of all cases of malaria outside Africa. The parasite is currently largely restricted to tropical and subtropical latitudes in Asia, Oceania, and the Americas. [...]
2020 - 10.1093/molbev/msz264
Molecular biology and evolution, Vol. 37, Issue 3 (March 2020) , p. 773-785  
2020-06-03
06:28
13 p, 1.8 MB Historical genomes reveal the genomic consequences of recent population decline in eastern gorillas / van der Valk, Tom (Uppsala University. Department of Ecology and Genetics (Sweden)) ; Díez-del-Molino, David (Swedish Museum of Natural History. Department of Bioinformatics and Genetics (Sweden)) ; Marquès i Bonet, Tomàs, 1975- (Institut Català de Paleontologia Miquel Crusafont) ; Guschanski, Katerina (Uppsala University. Department of Ecology and Genetics (Sweden)) ; Dalén, Love (Swedish Museum of Natural History. Department of Bioinformatics and Genetics (Sweden))
Many endangered species have experienced severe population declines within the last centuries [1, 2]. However, despite concerns about negative fitness effects resulting from increased genetic drift and inbreeding, there is a lack of empirical data on genomic changes in conjunction with such declines [3, 4, 5, 6, 7]. [...]
2019 - 10.1016/j.cub.2018.11.055
Current biology, Vol. 29, Issue 1 (January 2019) , p. 165-170  
2020-06-03
06:27
14 p, 2.5 MB First nearly complete skull of Gallotia auaritae (lower-middle Pleistocene, Squamata, Gallotiinae) and a morphological phylogenetic analysis of the genus Gallotia / Cruzado-Caballero, Penélope (Universidad Nacional de Río Negro. Instituto de Investigación en Paleobiología y Geología (Argentina)) ; Castillo Ruiz, Carolina (Universidad de La Laguna. Departamento de Biología Animal, Edafología y Geología) ; Bolet Mercadal, Arnau (Institut Català de Paleontologia Miquel Crusafont) ; Colmenero, Juan Ramón (Universidad de Salamanca. Departamento de Geología) ; De la Nuez, Julio (Universidad de La Laguna. Departamento de Biología Animal, Edafología y Geología) ; Casillas, Ramón (Universidad de La Laguna. Departamento de Biología Animal, Edafología y Geología) ; Llàcer, Sergio (Institut Català de Paleontologia Miquel Crusafont) ; Bernardini, Federico (The "Abdus Salam" International Centre for Theoretical Physics (Italy)) ; Fortuny Terricabras, Josep (Institut Català de Paleontologia Miquel Crusafont)
The Canary Islands are an Atlantic archipelago known for its high number of endemic species. Among the most known endemic vertebrate species are the giant lizards of the genus Gallotia. We describe the cranial osteology of the first almost complete and articulated fossil skull of the taxon Gallotia auaritae, recovered from the lower-middle Pleistocene of the La Palma island. [...]
2019 - 10.1038/s41598-019-52244-z
Scientific reports, Vol. 9 (November 2019) , art. 16629  
2020-03-17
18:02
11 p, 3.8 MB First continuous pre-Jaramillo to Jaramillo terrestrial vertebrate succession from Europe / Piñero, Pedro (Universitat Rovira i Virgili. Institut Català de Paleoecologia Humana i Evolució Social) ; Agustí, Jordi 1954- (Universitat Rovira i Virgili. Àrea de Prehistòria) ; Oms, Oriol (Universitat Autònoma de Barcelona. Departament de Geologia) ; Blain, Hugues Alexandre (Universitat Rovira i Virgili. Àrea de Prehistòria) ; Furió, Marc (Institut Català de Paleontologia Miquel Crusafont) ; Laplana, César (Museo Arqueológico Regional de la Comunidad de Madrid) ; Sevilla, Paloma (Universidad Complutense de Madrid. Departamento de Geodinámica, Estratigrafía y Paleontología) ; Rosas, Antonio (Museo Nacional de Ciencias Naturales. Departamento de Paleobiología) ; Vallverdú, Josep (Universitat Rovira i Virgili. Àrea de Prehistòria)
In this paper, the early Pleistocene small vertebrate sequence of Quibas-Sima (Quibas karstic complex, Murcia, SE Spain) is presented. The available magnetostratigraphic information together with the small vertebrate association, allow to reliably constrain the age of the different units. [...]
2020 - 10.1038/s41598-020-58404-w
Scientific reports, Vol. 10 (February 2020) , art. 1901