2024-06-25
09:54 |
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11 p, 2.6 MB |
CXCR4 Expression as a Prognostic Biomarker in Soft Tissue Sarcomas
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Virgili, Anna (Institut de Recerca Sant Pau) ;
Salazar, Juliana (Institut de Recerca Sant Pau) ;
Gallardo, Alberto (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
López Pousa, Antonio (Institut de Recerca Sant Pau) ;
Terés, Raúl (Institut de Recerca Sant Pau) ;
Bagué Rosell, Sílvia (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Orellana-Fernández, Ruth (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Fumagalli, Caterina (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Mangues, Ramon 1957- (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Alba-Castellón, Lorena (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Unzueta Elorza, Ugutz (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Casanova Rigat, Isolda (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Sebio, Ana (Institut de Recerca Sant Pau) ;
Universitat Autònoma de Barcelona
Poor long-term survival in localized high-risk soft tissue sarcomas (STSs) of the extremities and trunk highlights the need to identify new prognostic factors. CXCR4 is a chemokine receptor involved in tumor progression, angiogenesis, and metastasis. [...]
2024 -  10.3390/diagnostics14111195
Diagnostics, Vol. 14 Núm. 11 (june 2024) , p. 1195
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2024-06-25
09:53 |
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1 p, 222.8 KB |
Corrigendum : NK cell subsets changes in partial remission and early stages of pediatric type 1 diabetes(Front Immunol., 11, (611522), 10.3389/fimmu.2020.611522)
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Gómez Muñoz, Laia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Perna-Barrull, David (Institut Germans Trias i Pujol) ;
Villalba Felipe, Adrián (Institut Germans Trias i Pujol) ;
Rodríguez-Fernández, Silvia (Institut Germans Trias i Pujol) ;
Ampudia Carrasco, Rosa María (Institut Germans Trias i Pujol) ;
Teniente Serra, Aina (Institut Germans Trias i Pujol) ;
Vázquez, Federico (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Murillo-Vallés, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pérez Sánchez, Jacobo (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Corripio, Raquel (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
Bel, Joan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Vives Pi, Marta (Institut Germans Trias i Pujol)
In the published article, there was an error in the Funding statement. The Funding statement was displayed as "This work has been funded by the Spanish Government (FIS PI18/00436) co-financed with the European Regional Development funds (FEDER), and by DiabetesCero Foundation. [...]
2024 - 10.3389/fimmu.2024.1439246
Frontiers in immunology, Vol. 15 (2024) , p. 1439246
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2024-06-20
04:50 |
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38 p, 1.1 MB |
Spinal facilitation of descending motor input
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Taccola, Giuliano (University of Leeds) ;
Kissane, Roger (Department of Musculoskeletal & Ageing Science, University of Liverpool) ;
Culaclii, Stanislav (Department of Bioengineering, University of California,) ;
Apicella, Rosamaria (Neuroscience Department, International School for Advanced Studies (UTrieste, Itàlia)) ;
Liu, Wentai (University of California) ;
Gad, Parag (University of Southern California Neurorestoration Center) ;
Ichiyama, Ronaldo M. (University of Leeds) ;
Chakrabarty, Samit (University of Leeds) ;
Edgerton, Victor (Institut Germans Trias i Pujol. Institut Guttmann) ;
Universitat Autònoma de Barcelona
Highly varying patterns of electrostimulation (Dynamic Stimulation, DS) delivered to the dorsal cord through an epidural array with 18 independent electrodes transiently facilitate corticospinal motor responses, even after spinal injury. [...]
2023 - 10.1101/2023.06.30.547229
bioRxiv, july 2023
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2024-06-20
04:50 |
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9 p, 715.3 KB |
sPinal cOrd neUromodulatioN to treat Cerebral palsy in pEdiatrics : POUNCE Multisite Randomized Clinical Trial
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Girshin, Kristin (SpineX (Los Angeles, Estats Units d'Amèrica)) ;
Sachdeva, Rahul (Department of Medicine, University of British Columbia (Canadà)) ;
Cohn, Richard (Independent Consultant (Chapel Hill, Estat Units d'Amèrica)) ;
Gad, Parag (SpineX (Los Angeles, Estats Units d'Amèrica)) ;
Krassioukov, Andrei V. (University of British Columbia) ;
Edgerton, Victor (Institut Germans Trias i Pujol. Institut Guttmann) ;
Universitat Autònoma de Barcelona
Cerebral palsy (CP) affects up to 4 children in 1,000 live births, making it the most common motor disorder in children. It impairs the child's ability to move voluntarily and maintain balance and posture, and results in a wide range of other functional disorders during early development impairments in various sensory modalities, e. [...]
2023 - 10.3389/fnins.2023.1221809
Frontiers in Neuroscience, Vol. 17 (july 2023)
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2024-06-20
04:50 |
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2024-06-20
04:50 |
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12 p, 2.3 MB |
Safety and immunogenicity of a recombinant protein RBD fusion heterodimer vaccine against SARS-CoV-2
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Leal, Lorna (Universitat de Barcelona) ;
Pich, Judit (Hospital Clínic i Provincial de Barcelona) ;
Ferrer, Laura (HIPRA (Amer, Girona)) ;
Nava, Jocelyn (Hospital Clínic i Provincial de Barcelona) ;
Martí-Lluch, Ruth (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Esteban, Ignasi (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Pradenas, Edwards (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Raïch-Regué, Dàlia (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Prenafeta, Antoni (HIPRA (Amer, Girona)) ;
Nava, Jocelyn (Hospital Clínic i Provincial de Barcelona) ;
Escobar, Karla (Hospital Clínic i Provincial de Barcelona) ;
Pastor, Carmen (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Ribas-Aulinas, Marc (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Trinité, Benjamin (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Muñoz-Basagoiti, Jordana (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Domenech, Gemma (Institut d'Investigacions Biomédiques August Pi i Sunyer) ;
Clotet Sala, Bonaventura (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Corominas, Júlia (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Corpes-Comes, Aida (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Garriga, Carme (HIPRA (Amer, Girona)) ;
Barreiro, Antonio (HIPRA (Amer, Girona)) ;
Izquierdo Useros, Nuria (Instituto de Salud Carlos III) ;
Arnaiz, Joan Albert (Hospital Clínic i Provincial de Barcelona) ;
Soriano, A (Instituto de Salud Carlos III) ;
Ríos, José (Universitat Autònoma de Barcelona) ;
Nadal, Marga (Instituto de Investigación Biomédica de Girona Josep Trueta) ;
Plana, Montserrat (Instituto de Salud Carlos III) ;
Blanco, Julià (Institut Germans Trias i Pujol) ;
Prat, Teresa (HIPRA (Amer, Girona)) ;
Torroella, Elia (HIPRA (Amer, Girona)) ;
Ramos, Rafel (Universitat de Girona. Departament de Ciències Mèdiques)
In response to COVID-19 pandemic, we have launched a vaccine development program against SARS-CoV-2. Here we report the safety, tolerability, and immunogenicity of a recombinant protein RBD fusion heterodimeric vaccine against SARS-CoV-2 (PHH-1V) evaluated in a phase 1-2a dose-escalation, randomized clinical trial conducted in Catalonia, Spain. [...]
2023 - 10.1038/s41541-023-00736-5
NPJ Vaccines, Vol. 8 (september 2023)
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2024-06-20
04:50 |
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11 p, 902.5 KB |
Self-sampling monkeypox virus testing in high-risk populations, asymptomatic or with unrecognized Mpox, in Spain
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Agustí, Cristina (Institut Germans Trias i Pujol) ;
Martínez-Riveros, Héctor (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
Hernández-Rodríguez, Àgueda (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Casañ, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Díaz, Yesika (Centre of epidemiological studies on sexually transmitted infections and AIDS of Catalunya) ;
Alonso García, Lucía (Institut Germans Trias i Pujol. Fundació Lluita Contra les Infeccions) ;
Martró, Elisa (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Muñoz-Basagoiti, Jordana (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Gallemí, Marçal (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Folch, Cinta (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
Sönmez, Ibrahim (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
Adell, Héctor (ONG Stop (Barcelona)) ;
Villar, Marta (ONG Stop (Barcelona)) ;
París de León, Alexia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Martinez-Puchol, Sandra (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pelegrin, A. C. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Perez-Zsolt, Daniel (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Raïch-Regué, Dàlia (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Mora, Rubén (ONG Stop (Barcelona)) ;
Villegas, Luis (ONG Stop (Barcelona)) ;
Clotet Sala, Bonaventura (Institut Germans Trias i Pujol. Fundació Lluita Contra les Infeccions) ;
Izquierdo Useros, Nuria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Cardona, Pere-Joan (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Casabona-Barbarà, Jordi (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
The recent monkeypox virus (MPXV) outbreak was of global concern and has mainly affected gay, bisexual and other men who have sex with men (GBMSM). Here we assess prevalence of MPXV in high-risk populations of GBMSM, trans women (TW) and non-binary people without symptoms or with unrecognized monkeypox (Mpox) symptoms, using a self-sampling strategy. [...]
2023 - 10.1038/s41467-023-40490-9
Nature communications, Vol. 14 (october 2023)
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2024-06-20
04:50 |
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13 p, 3.2 MB |
Zinc deficiency impairs axonal regeneration and functional recovery after spinal cord injury by modulating macrophage polarization via NF-κB pathway
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Kijima, Ken (University of Southern California) ;
Ono, Gentaro (Department of Orthopedic Surgery, Kyushu University) ;
Kobayakawa, Kazu (Department of Orthopedic Surgery, Kyushu University) ;
Saiwai, Hirokazu (Department of Orthopedic Surgery, Kyushu University) ;
Hara, Masamitsu (Department of Orthopedic Surgery, Kyushu University) ;
Yoshizaki, Shingo (Department of Orthopedic Surgery, Kyushu University) ;
Yokota, Kazuya (Department of Orthopedic Surgery, Kyushu University) ;
Saito, Takeyuki (Department of Orthopedic Surgery, Kyushu University) ;
Tamaru, Tetsuya (Department of Orthopedic Surgery, Kyushu University) ;
Iura, Hirotaka (Department of Orthopedic Surgery, Kyushu University) ;
Haruta, Yohei (Department of Orthopedic Surgery, Kyushu University) ;
Kitade, Kazuki (Department of Orthopedic Surgery, Kyushu University) ;
Utsunomiya, Takeshi (Department of Orthopedic Surgery, Kyushu University) ;
Konno, Daijiro (Department of Energy and Materials, Kindai University) ;
Edgerton, Victor (Institut Germans Trias i Pujol. Institut Guttman) ;
Liu, Charles Y (University of Southern California) ;
Sakai, Hiroaki (Department of Orthopaedic Surgery, Spinal Injuries Center) ;
Maeda, Takeshi (Department of Orthopaedic Surgery, Spinal Injuries Center) ;
Kawaguchi, Kenichi (Department of Orthopedic Surgery, Kyushu University) ;
Matsumoto, Yoshihiro (Department of Orthopaedic Surgery, Fukushima Medical University) ;
Okada, Seiji (Department of Orthopedic Surgery, Osaka University Graduate School of Medicine) ;
Nakashima, Yasuharu (Department of Orthopedic Surgery, Kyushu University) ;
Universitat Autònoma de Barcelona
Spinal cord injury (SCI) is a devastating disease that results in permanent paralysis. Currently, there is no effective treatment for SCI, and it is important to identify factors that can provide therapeutic intervention during the course of the disease. [...]
2023 - 10.3389/fimmu.2023.1290100
Frontiers in immunology, Vol. 14 (november 2023)
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2024-06-20
04:50 |
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17 p, 1.6 MB |
Vaccination with an HIV T-Cell Immunogen (HTI) Using DNA Primes Followed by a ChAdOx1-MVA Boost Is Immunogenic in Gut Microbiota-Depleted Mice despite Low IL-22 Serum Levels
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Elizalde-Torrent, Aleix (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Borgognone, Alessandra (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Casadellà, Maria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Romero-Martín, Luis (Universitat Autonoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Escribà, Tuixent (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Parera, Mariona (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Rosales-Salgado, Yaiza (Institut Germans Trias i Pujol) ;
Díaz-Pedroza, Jorge (Institut Germans Trias i Pujol) ;
Català-Moll, Francesc (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Noguera-Julian, Marc (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Brander, Christian (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Paredes, Roger (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Olvera, Alex (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Universitat Autònoma de Barcelona
Despite the important role of gut microbiota in the maturation of the immune system, little is known about its impact on the development of T-cell responses to vaccination. Here, we immunized C57BL/6 mice with a prime-boost regimen using DNA plasmid, the Chimpanzee Adenovirus, and the modified Vaccinia Ankara virus expressing a candidate HIV T-cell immunogen and compared the T-cell responses between individuals with an intact or antibiotic-depleted microbiota. [...]
2023 - 10.3390/vaccines11111663
Vaccines (Basel), Vol. 11 (october 2023)
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2024-06-20
04:50 |
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14 p, 3.2 MB |
SIRT7 and p53 interaction in embryonic development and tumorigenesis
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Vazquez Prat, Berta Nieves (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Fernández-Duran, Irene (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Hernandez, Yurdiana (Rutgers University (Piscataway, Estats Units d'Amèrica)) ;
Tarighi, Shahriar (Max-Planck-Institute for Heart and Lung Research. Department of Cardiac Development and Remodeling) ;
Thackray, Joshua K. (Rutgers University (Piscataway, Estats Units d'Amèrica)) ;
Espinosa-Alcantud, Maria (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Kumari, Poonam (Max-Planck-Institute for Heart and Lung Research. Department of Cardiac Development and Remodeling) ;
Ianni, Alessandro (Max-Planck-Institute for Heart and Lung Research. Department of Cardiac Development and Remodeling) ;
Cesaire, Lionel (The City University of New York. Department of Science) ;
Braun, Thomas (Max-Planck-Institute for Heart and Lung Research. Department of Cardiac Development and Remodeling) ;
Esteller, M (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Tischfield, Jay (Rutgers University (Piscataway, Estats Units d'Amèrica)) ;
Vaquero, Alejandro (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Serrano, Lourdes (The City University of New York. Department of Science)
p53 is a hallmark tumor suppressor due in part to its role in cell cycle progression, DNA damage repair, and cellular apoptosis; its protein activity interrelates with the Sirtuin family of proteins, major regulators of the cellular response to metabolic, oxidative, and genotoxic stress. [...]
2024 - 10.3389/fcell.2023.1281730
Frontiers in Cell and Developmental Biology, Vol. 11 (january 2024)
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