2026-04-21
12:12 |
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2 p, 148.3 KB |
Effect of Onset-to-Admission Time and Care Bundle Achievement on Functional Outcomes in Patients With ICH: a population-based study
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Lambea-Gil, Álvaro (Institut de Recerca Sant Pau) ;
Abilleira i Castells, Sònia (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Amaro, Sergi (Hospital Clínic i Provincial de Barcelona) ;
Cárcel-Márquez, Jara (Institut de Recerca Sant Pau) ;
Cardona, Pere Joan (Hospital Universitari de Bellvitge) ;
Millán, Mònica (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pérez de la Ossa, Natalia (Institut de Recerca Sant Pau) ;
Rodriguez Campello, Ana Maria (Hospital del Mar (Barcelona, Catalunya)) ;
Rodriguez-Luna, David (Hospital Universitari Vall d'Hebron) ;
Salvat-Plana, Mercè (Agència de Qualitat i Avaluació Sanitàries de Catalunya (AQuAS)) ;
Seró, Laia (Hospital Universitari Joan XXIII de Tarragona) ;
Silva, Yolanda (Hospital Universitari de Girona Doctor Josep Trueta) ;
Camps-Renom, Pol (Institut de Recerca Sant Pau) ;
Cánovas Verge, David (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Ezcurra Diaz, Garbiñe (Institut de Recerca Sant Pau) ;
Fagundez, Olga (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Fernández Cadenas, Israel (Institut de Recerca Sant Pau) ;
Guasch-Jiménez, Marina (Institut de Recerca Sant Pau) ;
Martí-Fàbregas, Joan (Institut de Recerca Sant Pau) ;
Martínez-Domeño, Alejandro (Institut de Recerca Sant Pau) ;
Prats-Sánchez, Luis Antonio (Institut de Recerca Sant Pau) ;
Ramos-Pachón, Anna (Institut de Recerca Sant Pau) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Background and objectives: Intracerebral hemorrhage (ICH) remains a leading cause of morbidity and mortality, with limited effective treatments. Early implementation of a care bundle protocol (CBP) within 6 hours of symptom onset has been shown to improve functional outcomes, although its effect beyond this time frame remains unclear. [...]
2025 -  10.1212/WNL.0000000000214176
Neurology, Vol. 105, Num. 8 ( October 2025) , p
2 documents
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2026-04-20
14:12 |
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2026-04-20
14:12 |
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9 p, 328.5 KB |
The impact of thyroid disorders on the gut microbiome : emerging mechanisms and clinical relevance
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Silva, Isabela Busto (Serviço de Endocrinologia e Metabologia do Hospital de Clínicas da Universidade Federal do Paraná (Curitiba, Brasil)) ;
Puig Domingo, Manuel (Institut Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
The thyroid-gut axis represents a dynamic interaction between the intestinal microbiota and thyroid function, with growing evidence linking gut dysbiosis to thyroid diseases. The gut microbiome, comprising over 100 trillion microorganisms, influences immune modulation, iodine metabolism, and thyroid hormone regulation. [...]
2025 - 10.20945/2359-4292-2025-0075
Archives of Endocrinology and Metabolism, Vol. 70 (November 2025) , art. e250075
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2026-04-21
10:12 |
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10 p, 1.6 MB |
Tinzaparin for the prevention of thromboembolic events in ambulatory patients with metastatic colorectal cancer receiving first line treatment : a randomised, clinical trial design
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Salgado, Mercedes (Complexo Hospitalario de Ourense) ;
de la Camara-Gómez, Juan (Complexo Hospitalario Universitario A Coruna) ;
García-Escobar, Ignacio (Hospital General Universitario de Toledo) ;
Álvarez-Llosa, Renata-Carola (Complexo Hospitalario de Ourense) ;
González-Villarroel, Paula (Alvaro Cunqueiro Hospital (Vigo, Espanya)) ;
Garay, David Fernández (Hospital Costa del Sol (Marbella)) ;
Pàmpols-Felip, Montse (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Guillot-Morales, Mónica (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Pelegrín-Mateo, Francisco José (Zuwe Hofpoort Hospital) ;
Jimenez-Orozco, Encarnación (Hospital Universitario Jerez de La Frontera (Andalusia)) ;
Sastre Valera, Javier (Hospital Clínico San Carlos (Madrid)) ;
Martínez de Castro, Eva (Hospital Universitario Marqués de Valdecilla (IDIVAL)) ;
Coma, Eva (Institut Català d'Oncologia) ;
Bouzas, Lorena París (Centro Oncológico de Galicia) ;
Ferrer-Pérez, Ana Isabel (Hospital Obispo Polanco (Terol, Aragó)) ;
Mompradé-Olivé, Elisabet (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Cousillas, Antía (Complejo Hospitalario Universitario de Pontevedra) ;
Covela-Rúa, Marta (Hospital Universitario Lucus Augusti (Lugo)) ;
Rojas, Mariam (Hospital Clínic i Provincial de Barcelona) ;
Querol, Rosa (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Robles-Díaz, Luis (Hospital Universitario 12 de Octubre (Madrid)) ;
Merino, Marta (LEO Pharma (Barcelona)) ;
Gil Raga, Mireia (Hospital General Universitari de València) ;
Sánchez Cánovas, Manuel (Hospital General Universitario Morales Meseguer (Múrcia)) ;
Elías, Teresa (Hospital Universitario Virgen del Rocío. Instituto de Biomedicina (IBIS)) ;
Marrupe-González, David (Hospital Universitario de Móstoles (Madrid)) ;
Carmona-Campos, Marta (Hospital Clínico Universitario de Santiago CHUS) ;
Soria Fernández, José Manuel (Institut de Recerca Sant Pau) ;
Muñoz Martin, Andrés (Universidad Complutense de Madrid) ;
Sánchez-Gil, Belén (Hospital General La Mancha Centro (Ciutat Reial)) ;
García-Ferrón, María (Hospital Infanta Cristina de Parla) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Colorectal cancer (CRC) is the third most commonly diagnosed cancer worldwide. CRC leads to increased activation of the clotting system. Since CRC patients present a higher rate of bleeding, careful evaluation of the risk/benefits of anticoagulant prophylaxis is necessary. [...]
2025 - 10.1186/s12885-025-14620-z
BMC Cancer, Vol. 25 (November 2025) , art. 1773
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2026-04-21
11:12 |
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10 p, 217.8 KB |
Comorbidities as a Personalized Target in Patients with Severe Asthma Treated with Dupilumab
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Gonzalez-Lluch, Carlota (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Basagaña Torrentó, Maria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pardo, Laura (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Cruz Toro, Paula (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Hernández-Biette, Agnés (Universitat Autonònoma de Barcelona. Departament de Medicina) ;
Martínez Rivera, Carlos (Universitat Autonònoma de Barcelona. Departament de Medicina) ;
Garcia-Olivé, Ignasi (Universitat Autonònoma de Barcelona. Departament de Medicina)
Background: This study aimed to evaluate the clinical effectiveness of dupilumab and its impact on CRSwNP and type 2 inflammatory biomarkers in patients with severe uncontrolled asthma, with or without comorbidities, within a real-life cohort. [...]
2025 - 10.3390/jpm15100471
Journal of personalized medicine, Vol. 15 (October 2025) , art. 471
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2026-04-16
13:12 |
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15 p, 482.1 KB |
Closed-Incision Negative Pressure Therapy : Scoping Review and Multidisciplinary Consensus Recommendations of the Spanish Observatory of Infection in Surgery
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Badia, Josep M. (Universitat Internacional de Catalunya) ;
Rubio-Pérez, Inés (Hospital Universitario La Paz (Madrid)) ;
Morales-Pérez, Carlos (Hospital Universitario Central de Asturias) ;
Bueno-Lledó, José (Universitat de València) ;
Rodríguez-Lorenzo, Laura M. (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Sancho Insenser, Joan Josep (Hospital del Mar (Barcelona, Catalunya)) ;
Marín-Peña, Oliver (Hospital Universitario Infanta Leonor) ;
López, Susana (Institut de Recerca Sant Pau) ;
Masià, Jaume (Institut de Recerca Sant Pau) ;
Balibrea Del Castillo, José María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Surgical site infections (SSI) and surgical site complications (SSC) significantly impact surgery outcomes, increasing hospital stays and mortality rates, and negatively affecting patients' quality of life. [...]
2025 - 10.1111/iwj.70750
International Wound Journal, Vol. 22 (October 2025) , art. e70750
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2026-04-08
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14 p, 916.8 KB |
Barriers to Deprescribing Benzodiazepines in Older Adults in a Survey of European Physicians
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Salvà Casanovas, Antonio (Universitat Autònoma de Barcelona. Fundació Salut i Envelliment UAB) ;
Miralles Basseda, Ramon (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Shapoval, Vladyslav (Université catholique de Louvain (UCLouvain)) ;
de Saint Hubert, Marie (Institute of Health and Society (IRSS). UCLouvain) ;
Evrard, Perrine (Université catholique de Louvain (UCLouvain)) ;
Sibille, François Xavier (Institute of Health and Society (IRSS). UCLouvain) ;
Aubert, Carole E. (University of Bern) ;
Bolt, Lucy (University of Bern) ;
Tsoutsi, Vagioula (National & Kapodistrian University of Athens) ;
Kollia, Pinelopi (National & Kapodistrian University of Athens) ;
Wichniak, Adam (Third Department of Psychiatry. Institute of Psychiatry and Neurology) ;
Gustavsson, Katarzyna (Department of Science and Evaluation. Medical Research Agency) ;
Wyller, Torgeir Bruun (University of Oslo) ;
Callegari, Enrico (Østfold Hospital Trust (Noruega)) ;
Grimshaw, Jeremy M. (University of Ottawa) ;
Presseau, Justin (University of Ottawa) ;
Henrard, Séverine (Institute of Health and Society (IRSS). UCLouvain) ;
Spinewine, Anne (CHU UCLouvain Namur)
IMPORTANCE The use of benzodiazepine receptor agonists (BZRA) poses serious health risks to older adults. Although several guidelines recommend deprescribing, implementation in clinical practice remains limited. [...]
2025 - 10.1001/jamanetworkopen.2024.59883
JAMA network open, Vol. 8, Num. 3 (2025) , art. e2459883
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2026-04-15
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12 p, 509.3 KB |
Implementing Semi-Automated Medication Dispensing for People with HIV : A Community-Based Alternative to Traditional Pharmacy Pickups
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Hernández-Sánchez, Diana (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Saz, Jorge (Projecte dels NOMS Hispanosida-BCN Checkpoint (Barcelona)) ;
García Gimenez, Ignacio (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Puig, Jordi (Universitat Autònoma de Barcelona. Departament d'Infermeria) ;
Rivero, Ángel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Valero Valdelvira, Patricia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
López Martínez, María Isabel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Muñoz, Rafael (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Quiñones Ribas, Carles (Hospital Universitari de Girona Doctor Josep Trueta) ;
Davins Riu, Meritxell (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Negredo Puigmal, Eugènia (Institut Germans Trias i Pujol. Fundació Lluita Contra les Infeccions)
Introduction: Maintaining adherence and access to antiretroviral treatment is basic for good management of people with HIV (PWH), while enhancing patient satisfaction. With the aim of shifting from drug-centered into patient-centered care and integrating care interventions into community settings, here we share an outpatient hospital pharmaceutical care implementation model for PWH. [...]
2026 - 10.3390/healthcare14040429
Healthcare, Vol. 14, Num. 4 (February 2026) , p. 429
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2026-03-17
15:36 |
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12 p, 1.5 MB |
Autologous stem cell transplantation for relapsed/refractory large B-cell lymphoma : a multicenter GETH-TC/GELTAMO study
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Bento, Leyre (Hospital Universitario Son Espases. Instituto de Investigación Sanitaria de Baleares) ;
González-Sierra, Pedro Antonio (Hospital Universitario Son Espases. Instituto de Investigación Sanitaria de Baleares) ;
Martínez, Carmen (Hospital Clínic i Provincial de Barcelona) ;
Caballero, Ana Carolina (Institut de Recerca Sant Pau) ;
Peña, Marta (Institut Català d'Oncologia) ;
Pérez, Ariadna (Hospital Clínic Universitari (València)) ;
Jiménez-Ubieto, Ana (Hospital 12 de Octubre (Madrid)) ;
Medina, Lucía (Hospital 12 de Octubre (Madrid)) ;
Bastos, Mariana (Hospital General Universitario Gregorio Marañón) ;
Navarro, Belén (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Salcedo, Isabel (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Abrisqueta, Pau (Hospital Universitari Vall d'Hebron) ;
Español, Ignacio (Hospital Universitario Virgen de la Arrixaca (Múrcia)) ;
Cornago, Javier (Hospital Universitario Fundación Jiménez Díaz) ;
Martín-Moro, Fernando (Instituto Ramón y Cajal de Investigación Sanitaria (Madrid)) ;
García, Lucía (Hospital General Universitario Morales Meseguer (Múrcia)) ;
Gómez, Pilar (Hospital Universitario La Paz (Madrid)) ;
Varela, María Rosario (Complejo Hospitalario Universitario de A Coruña) ;
Zanabili, Joud (Hospital Universitario Central de Asturias) ;
Zudaire, Teresa (Hospital Universitario de Navarra) ;
Zeberio, Izaskun (Hospital de Donostia (Sant Sebastià, País Basc)) ;
del Campo, Raquel (Hospital Universitari Son Llàtzer (Palma de Mallorca, Balears)) ;
González, Pedro (Hospital Universitario Virgen de las Nieves (Granada)) ;
Sitges, Marta (Institut Català d'Oncologia) ;
Cabero, Almudena (Hospital Universitario de Salamanca) ;
Mussetti, Alberto (Institut Català d'Oncologia) ;
Montoro, Juan (Hospital Universitari i Politècnic La Fe (València)) ;
Sampol, Antonia (Hospital Universitario Son Espases. Instituto de Investigación Sanitaria de Baleares) ;
Sureda, Anna (Institut Català d'Oncologia) ;
Caballero, Dolores (Hospital Universitario de Salamanca) ;
Martín García-Sancho, Alejandro (Hospital Universitario de Salamanca) ;
Consejo Ortí Verdet, María (Hospital Universitari i Politècnic La Fe (València)) ;
Sorribes, Marina (Institut de Recerca Sant Pau) ;
Caldas-González, Paula Fernández (Hospital General Universitario Gregorio Marañón) ;
Puente, María (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
González Pinedo, Leslie ;
Blázquez-Goñi, Cristina (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Rovira, Jordina (Hospital Universitari Joan XXIII de Tarragona) ;
Franch-Sarto, Mireia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
We performed a retrospective multicenter study including 791 patients with relapsed/ refractory (R/R) large B-cell lymphoma (LBCL) who underwent autologous stem cell transplantation (ASCT). After a median follow-up of 74 months from infusion, 65% were alive and 84% free of disease. [...]
2025 - 10.1182/bloodadvances.2024015415
Blood advances, Vol. 9, Num. 13 (August 2025) , p. 3281-3292
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2026-03-11
16:12 |
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9 p, 716.0 KB |
Guideline-directed medical therapy after revascularization and outcomes in ischaemic cardiomyopathy
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Moliner-Abós, Carles (Hospital Universitari de Girona Doctor Josep Trueta) ;
Calvo-Barceló, Maria (Hospital Universitari Vall d'Hebron) ;
Solé González, Eduard (Hospital Clínic i Provincial de Barcelona) ;
Borrellas Martín, Andrea (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Fluvià Brugués, Paula (Institut d'Investigació Biomèdica (Girona)) ;
Sánchez Vega, Jesus (Hospital Universitari de Bellvitge) ;
Vime Jubany, Joan (Hospital Universitari Sant Joan de Reus (Tarragona)) ;
Ferré Vallverdú, Maria (Hospital Universitari Sant Joan de Reus (Tarragona)) ;
Tauron, Manel (Institut de Recerca Sant Pau) ;
Tobias Castillo, Pablo Eduardo (Hospital Universitari Vall d'Hebron) ;
de la Fuente Mancera, Juan Carlos (Hospital Clínic i Provincial de Barcelona) ;
Vilardell Rigau, Pau (Institut d'Investigació Biomèdica (Girona)) ;
Vila Olives, Rosa (Hospital Universitari Vall d'Hebron) ;
Diez López, Carles (Hospital Universitari de Bellvitge) ;
Bayés-Genís, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Arzamendi, Dabit (Institut de Recerca Sant Pau) ;
Ferreira-Gonzalez, Ignacio (Hospital Universitari Vall d'Hebron) ;
Mirabet Pérez, Sonia (Institut de Recerca Sant Pau) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Guideline-directed medical therapy (GDMT) remains the cornerstone for treating patients with heart failure (HF) and reduced ejection fraction (HFrEF) and coronary artery disease (CAD). However, real-world implementation of GDMT (GDMTi) is suboptimal. [...]
2025 - 10.1002/ehf2.70014
ESC Heart Failure, Vol. 12, Num. 6 (November 2025) , p. 4442-4450
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