2026-04-23
15:12 |
|
9 p, 243.1 KB |
Cardioprotection with intravenous statin administration during myocardial infarction vs. oral preloading : a preclinical study
/
Otero, Sergi (Universitat Autònoma de Barcelona) ;
Radikė, Monika (Liverpool Heart and Chest Hospital) ;
Ben-Aicha Gonzalez, Soumaya (Imperial College London (Londres, Regne Unit)) ;
Mendieta, Guiomar (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Gutiérrez, Manuel (Liverpool Heart and Chest Hospital) ;
Sutelman, Pablo (Institut de Recerca Sant Pau) ;
Borrell-Pages, Maria (Institut de Recerca Sant Pau) ;
Hidalgo, Alberto (Hospital Universitari de Girona Doctor Josep Trueta) ;
Badimon, Lina (Institut de Recerca Sant Pau) ;
Vilahur, Gemma (Institut de Recerca Sant Pau)
Infarct size is associated with all-cause mortality and heart failure hospitalization underscoring the need for effective cardioprotection beyond timely reperfusion. 1 Guidelines recommend administering high-potency statins early after ST-elevation myocardial infarction (STEMI) in order to reduce LDL-cholesterol levels as soon as possible. [...]
2026 -  10.1093/eurheartj/ehag269
European heart journal, April 2026, art. ehag269
|
|
2026-04-22
12:12 |
|
13 p, 4.3 MB |
Cortical microstructure is associated with disease severity and clinical progression in genetic frontotemporal dementia : a GENFI study
/
Rodriguez-Vieitez, Elena (Karolinska University Hospital) ;
Rydell, Melissa T. (Karolinska University Hospital) ;
Ullgren, Abbe (Karolinska University Hospital) ;
Montal, Victor (Barcelona Supercomputing Center) ;
Illán-Gala, Ignacio (Institut de Recerca Sant Pau) ;
Fortea, Juan (Institut de Recerca Sant Pau) ;
Jelic, Vesna (Karolinska University Hospital) ;
Bouzigues, Arabella (Sorbonne Université) ;
Russell, Lucy L. (University College London. Institute of Neurology) ;
Foster, Phoebe H. (University College London. Institute of Neurology) ;
Ferry-Bolder, Eve (University College London. Institute of Neurology) ;
van Swieten, John C. (Erasmus Medical Centre (Rotterdam, Països Baixos)) ;
Jiskoot, Lize C. (Erasmus Medical Centre (Rotterdam, Països Baixos)) ;
Seelaar, Harro (Erasmus Medical Centre (Rotterdam, Països Baixos)) ;
Sanchez-Valle, Raquel (Hospital Clínic i Provincial de Barcelona) ;
Laforce, Robert (Université Laval) ;
Galimberti, Daniela (University of Milan) ;
Vandenberghe, Rik (Katholieke Universiteit te Leuven (1970- )) ;
de Mendonça, Alexandre (University of Lisbon) ;
Tiraboschi, Pietro (Fondazione IRCCS Istituto Neurologico Carlo Besta (Milà, Itàlia)) ;
Santana, Isabel (University of Coimbra (Coïmbra, Portugal)) ;
Gerhard, Alexander (University Hospital Essen (Alemanya)) ;
Levin, Johannes (German Center for Neurodegenerative Diseases (DZNE)) ;
Sorbi, Sandro (Istituto di Ricovero e Cura A Carattere Scientifico (IRCCS)) ;
Otto, M. (Martin-Luther University Halle-Wittenberg) ;
Pasquier, Florence (University of Lille and INSERM 1172) ;
Ducharme, Simon (McConnell Brain Imaging Centre) ;
Butler, Chris R. (Imperial College London) ;
Le Ber, Isabelle (Sorbonne Université) ;
Finger, Elizabeth (University of Western Ontario) ;
Tartaglia, Maria Carmela (University of Toronto) ;
Masellis, Mario (University of Toronto) ;
Rowe, James B. (University of Cambridge) ;
Synofzik, Matthis (Center for Neurodegenerative Diseases (DZNE)) ;
Moreno, Fermin (Instituto de Salud Carlos III) ;
Borroni, Barbara (IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli (Brescia, Itàlia)) ;
Rohrer, Jonathan D. (University College London. Institute of Neurology) ;
Westman, Eric (Karolinska Institutet) ;
Graff, Caroline (Karolinska University Hospital. Unit for Hereditary Dementias, Theme Inflammation and Aging) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
The study of genetic frontotemporal dementia (FTD) allows investigating its earliest presymptomatic stages. Using cross-sectional T1-weighted and diffusion-weighted MRI, we test the hypothesis that cortical microstructural alterations, quantified as cortical mean diffusivity (cMD), are detectable earlier and are more strongly associated with clinical progression than cortical thickness (CTh). [...]
2025 - 10.1038/s41380-025-03280-x
Molecular psychiatry, Vol. 30 (October 2025) , p. 5800-5812
|
|
2026-04-21
12:12 |
|
2 p, 148.3 KB |
Effect of Onset-to-Admission Time and Care Bundle Achievement on Functional Outcomes in Patients With ICH: a population-based study
/
Lambea-Gil, Álvaro (Institut de Recerca Sant Pau) ;
Abilleira i Castells, Sònia (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Amaro, Sergi (Hospital Clínic i Provincial de Barcelona) ;
Cárcel-Márquez, Jara (Institut de Recerca Sant Pau) ;
Cardona, Pere Joan (Hospital Universitari de Bellvitge) ;
Millán, Mònica (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pérez de la Ossa, Natalia (Institut de Recerca Sant Pau) ;
Rodriguez Campello, Ana Maria (Hospital del Mar (Barcelona, Catalunya)) ;
Rodriguez-Luna, David (Hospital Universitari Vall d'Hebron) ;
Salvat-Plana, Mercè (Agència de Qualitat i Avaluació Sanitàries de Catalunya (AQuAS)) ;
Seró, Laia (Hospital Universitari Joan XXIII de Tarragona) ;
Silva, Yolanda (Hospital Universitari de Girona Doctor Josep Trueta) ;
Camps-Renom, Pol (Institut de Recerca Sant Pau) ;
Cánovas Verge, David (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Ezcurra Diaz, Garbiñe (Institut de Recerca Sant Pau) ;
Fagundez, Olga (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Fernández Cadenas, Israel (Institut de Recerca Sant Pau) ;
Guasch-Jiménez, Marina (Institut de Recerca Sant Pau) ;
Martí-Fàbregas, Joan (Institut de Recerca Sant Pau) ;
Martínez-Domeño, Alejandro (Institut de Recerca Sant Pau) ;
Prats-Sánchez, Luis Antonio (Institut de Recerca Sant Pau) ;
Ramos-Pachón, Anna (Institut de Recerca Sant Pau) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Background and objectives: Intracerebral hemorrhage (ICH) remains a leading cause of morbidity and mortality, with limited effective treatments. Early implementation of a care bundle protocol (CBP) within 6 hours of symptom onset has been shown to improve functional outcomes, although its effect beyond this time frame remains unclear. [...]
2025 - 10.1212/WNL.0000000000214176
Neurology, Vol. 105, Num. 8 ( October 2025) , p
2 documents
|
|
2026-04-22
13:12 |
|
12 p, 298.7 KB |
Predictors of response to omalizumab and relapse in chronic spontaneous Urticaria : a narrative review focusing on parameters available in routine clinical practice
/
Mateu Arrom, Laura (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Puig-Verdié, Lluís (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Spertino, Jorge (Institut de Recerca Sant Pau) ;
Vence Nogueira, Xenevra Adriana (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Chronic spontaneous urticaria (CSU) is a heterogeneous disease with variable responses to treatment. Identifying predictors of response to omalizumab and relapse after its discontinuation is essential for optimizing management. [...]
2025 - 10.3389/falgy.2025.1688464
Frontiers in Allergy, Vol. 6 (October 2025) , art. 1688464
|
|
2026-04-21
09:12 |
|
9 p, 872.3 KB |
Robot-Assisted Salvage Prostatectomy : External Validation of the EAU Selection Criteria and Identification of the Optimal Candidate: A Junior ERUS/YAU Collaborative Study
/
Wenzel, Mike (Goethe University Hospital Frankfurt) ;
Würnschimmel, Christoph (Luzerner Kantonsspital (Suïssa)) ;
Nathan, Arjun (University College London Hospitals NHS Foundation Trust) ;
Moschovas, Marcio Covas (AdventHealth Global Robotics Institute) ;
Wagner, Christian (Prostate Center Northwest, St. Antonius-Hospital) ;
Calleris, Giorgio (University of Turin and Città della Salute e della Scienza) ;
Di Maida, Fabrizio (Università degli Studi di Firenze) ;
Rivas, Juan Gomez (Hospital Clínico San Carlos (Madrid)) ;
Bravi, Carlo Andrea (ORSI Academy) ;
Groote, Ruben De (ORSI Academy) ;
Piramide, Federico (University of Turin) ;
Turri, Filippo (University of Milan) ;
Kowalczyk, Keith (MedStar Georgetown University Hospital) ;
Sharma, Gopal (Medanta - The Medicity) ;
Andras, Iulia (Iuliu Hatieganu University of Medicine and Pharmacy) ;
Lambert, Edward (Universitair Ziekenhuis Gent) ;
Liakos, Nikolaos (Medical Centre of the University of Freiburg) ;
Darlington, Danny (Royal Surrey County Hospital) ;
Paciotti, Marco (Humanitas Research Hospital - IRCCS) ;
Sorce, Gabriele (Istituto di Ricovero e Cura A Carattere Scientifico (IRCCS)) ;
Mandel, Philipp (Goethe University Hospital Frankfurt) ;
Galfano, Antonio (ASST Grande Ospedale Metropolitano Niguarda) ;
Nathan, Senthil (University College London Hospitals NHS Foundation Trust) ;
Marra, Giancarlo (University of Turin and Città della Salute e della Scienza) ;
Dell'Oglio, Paolo (ASST Grande Ospedale Metropolitano Niguarda) ;
Mottrie, Alexandre (ORSI Academy) ;
Chun, Felix K. H. (Goethe University Hospital Frankfurt) ;
Patel, Vipul (AdventHealth Global Robotics Institute) ;
Breda, Alberto (Institut de Recerca Sant Pau) ;
Larcher, Alessandro (Istituto di Ricovero e Cura A Carattere Scientifico (IRCCS)) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Background: EAU guidelines recommend salvage radical prostatectomy (sRP) only in highly selected patients with recurrent prostate cancer in experienced centers. Methods: The Junior ERUS/Young Academic Urologist Working Group on Robot-Assisted Surgery conducted a multicentric project to investigate biochemical recurrence-free (BCR), metastases-free (MFS), and overall survival (OS) outcomes in robotic sRP patients stratified according to EAU criteria. [...]
2025 - 10.1002/pros.70048
The Prostate, Vol. 86 (September 2025) , p. 3-11
|
|
2026-04-21
09:12 |
|
9 p, 1.6 MB |
SynaptopathyDB integrates synaptic proteomes, genetic and phenotypic data to advance research on nervous system disorders
/
Bayés, Àlex (Institut de Recerca Sant Pau) ;
Grant, Seth G. N. (University of Edinburgh) ;
Sorokina, Oksana (University of Edinburgh) ;
Dominic, Digin (University of Edinburgh) ;
Armstrong, J. Douglas (University of Edinburgh) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Synaptic dysfunction resulting from pathogenic variants in genes encoding synaptic proteins is a major contributor to brain and behavioural disorders, collectively termed synaptopathies. To facilitate research into the genetic basis and clinical manifestations of synaptopathy we have created SynaptopathyDB, an online resource that integrates data from 64 mammalian synapse proteomic studies and multiple genetic and phenotypic resources (). [...]
2025 - 10.1038/s41598-025-26969-z
Scientific reports, Vol. 15 (December 2025) , art. 42986
|
|
2026-04-22
16:12 |
|
10 p, 1016.3 KB |
Pre-emptive TIPS should be considered in high-risk patients with both acute variceal bleeding and severe alcohol-related hepatitis
/
Rudler, Marika (La Pitié-Salpêtrière Hospital) ;
Hernández-Gea, Virginia (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Larrue, Helene (Service d'Hépatologie Hôpital Rangueil CHU Toulouse et Université de Toulouse, Toulouse, France) ;
Charlotte Bouzbib (La Pitié-Salpêtrière Hospital) ;
Procopet, Bogdan (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Baiges, Anna (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Turon, Fanny (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Villanueva, Càndid (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Albillos, Agustín (Hospital Universitario Ramón y Cajal (Madrid)) ;
Alvarado-Tapias, Edilmar (Institut de Recerca Sant Pau) ;
Gluud, Lise Lotte (Copenhagen University Hospital) ;
Praktiknjo, Michael (University Hospital Bonn (Bonn, Alemanya)) ;
Genescà Ferrer, Joan (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Ventura-Cots, Meritxell (Vall d'Hebron Institut de Recerca (VHIR)) ;
Villagrasa, Ares (Vall d'Hebron Institut de Recerca (VHIR)) ;
Rodrigues, S. (Centro Hospitalar São João) ;
Mouri Sarah (La Pitié-Salpêtrière Hospital) ;
Giráldez-Gallego, Álvaro (Hopital Universitario Virgen del Rocío) ;
Masnou, Helena (IRCCS Ca' Granda Maggiore Hospital Foundation) ;
Laleman, Wim (University Hospital Bonn (Bonn, Alemanya)) ;
Bureau, Christophe (Service d'Hépatologie Hôpital Rangueil CHU Toulouse et Université de Toulouse, Toulouse, France) ;
Robic, Marie Angèle (Service d'Hépatologie Hôpital Rangueil CHU Toulouse et Université de Toulouse, Toulouse, France) ;
Hartl, Lukas (Medical University of Vienna) ;
Tellez, Luis (Hospital Universitario Ramón y Cajal (Madrid)) ;
Zipprich, Alexander (Martin Luther University Halle-Wittenberg) ;
Cañete Hidalgo, Nuria (Hospital del Mar (Barcelona, Catalunya)) ;
Sultanik, Philippe (La Pitié-Salpêtrière Hospital) ;
Deckmyn, Olivier (BioPredictive, Paris) ;
Mandorfer, Mattias (Medical University of Vienna) ;
Senzolo, Marco (University Hospital of Padova (Pàdua, Itàlia)) ;
Schepis, Filippo (University of Modena and Reggio Emilia) ;
Tripathi, Dhiraj (University Hospitals Birmingham NHS Foundation Trust (Birmingham, Regne Unit)) ;
García-Pagán, JC. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Thabut, Dominique (La Pitié-Salpêtrière Hospital)
Severe alcohol-related hepatitis (AH) and acute variceal bleeding (AVB) may occur simultaneously. The impact of a pre-emptive transjugular intrahepatic portosystemic shunt (pTIPS) in high-risk patients (patients with Child-Pugh (CP) B and active bleeding or CP C10-13 cirrhosis) with AVB and concomitant severe AH is unknown. [...]
2025 - 10.1016/j.jhepr.2025.101611
JHEP Reports, Vol. 7, Num. 12 (September 2025) , art. 101611
|
|
2026-04-21
10:12 |
|
10 p, 1.6 MB |
Tinzaparin for the prevention of thromboembolic events in ambulatory patients with metastatic colorectal cancer receiving first line treatment : a randomised, clinical trial design
/
Salgado, Mercedes (Complexo Hospitalario de Ourense) ;
de la Camara-Gómez, Juan (Complexo Hospitalario Universitario A Coruna) ;
García-Escobar, Ignacio (Hospital General Universitario de Toledo) ;
Álvarez-Llosa, Renata-Carola (Complexo Hospitalario de Ourense) ;
González-Villarroel, Paula (Alvaro Cunqueiro Hospital (Vigo, Espanya)) ;
Garay, David Fernández (Hospital Costa del Sol (Marbella)) ;
Pàmpols-Felip, Montse (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Guillot-Morales, Mónica (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Pelegrín-Mateo, Francisco José (Zuwe Hofpoort Hospital) ;
Jimenez-Orozco, Encarnación (Hospital Universitario Jerez de La Frontera (Andalusia)) ;
Sastre Valera, Javier (Hospital Clínico San Carlos (Madrid)) ;
Martínez de Castro, Eva (Hospital Universitario Marqués de Valdecilla (IDIVAL)) ;
Coma, Eva (Institut Català d'Oncologia) ;
Bouzas, Lorena París (Centro Oncológico de Galicia) ;
Ferrer-Pérez, Ana Isabel (Hospital Obispo Polanco (Terol, Aragó)) ;
Mompradé-Olivé, Elisabet (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Cousillas, Antía (Complejo Hospitalario Universitario de Pontevedra) ;
Covela-Rúa, Marta (Hospital Universitario Lucus Augusti (Lugo)) ;
Rojas, Mariam (Hospital Clínic i Provincial de Barcelona) ;
Querol, Rosa (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Robles-Díaz, Luis (Hospital Universitario 12 de Octubre (Madrid)) ;
Merino, Marta (LEO Pharma (Barcelona)) ;
Gil Raga, Mireia (Hospital General Universitari de València) ;
Sánchez Cánovas, Manuel (Hospital General Universitario Morales Meseguer (Múrcia)) ;
Elías, Teresa (Hospital Universitario Virgen del Rocío. Instituto de Biomedicina (IBIS)) ;
Marrupe-González, David (Hospital Universitario de Móstoles (Madrid)) ;
Carmona-Campos, Marta (Hospital Clínico Universitario de Santiago CHUS) ;
Soria Fernández, José Manuel (Institut de Recerca Sant Pau) ;
Muñoz Martin, Andrés (Universidad Complutense de Madrid) ;
Sánchez-Gil, Belén (Hospital General La Mancha Centro (Ciutat Reial)) ;
García-Ferrón, María (Hospital Infanta Cristina de Parla) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Colorectal cancer (CRC) is the third most commonly diagnosed cancer worldwide. CRC leads to increased activation of the clotting system. Since CRC patients present a higher rate of bleeding, careful evaluation of the risk/benefits of anticoagulant prophylaxis is necessary. [...]
2025 - 10.1186/s12885-025-14620-z
BMC Cancer, Vol. 25 (November 2025) , art. 1773
|
|
2026-04-21
14:12 |
|
13 p, 2.7 MB |
Sources of essential lipids for Mycoplasma pneumoniae via P116 to target liver and atherosclerotic lesions
/
Vizarraga, David (Parc Científic de Barcelona. Instituto de Biología Molecular de Barcelona (IBMB-CSIC)) ;
Marcos, Marina (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Rotllan, Noemi (Institut de Recerca Sant Pau) ;
Martín Sánchez, Jesús (Parc Científic de Barcelona. Instituto de Biología Molecular de Barcelona (IBMB-CSIC)) ;
Santos, David (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Camacho, Mercedes (Institut de Recerca Sant Pau) ;
Soto, Begoña (Institut de Recerca Sant Pau) ;
Guerra, Pablo (Institut de Biologia Molecular de Barcelona) ;
Wu, Wanlu (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Serrano, Luis (ICREA (Institució Catalana d'Investigació i Estudis Avançats)) ;
Piñol Ribas, Jaume (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Fita, Ignacio (Parc Científic de Barcelona. Instituto de Biología Molecular de Barcelona (IBMB-CSIC)) ;
Escolà-Gil, Joan Carles (Institut de Recerca Sant Pau) ;
Velasco Reniu, Lorena (Institut de Recerca Sant Pau) ;
Pareja, Félix (Clínica Universidad de Navarra) ;
Collantes, María (Instituto de Investigación Sanitaria de Navarra) ;
Rodriguez Arce, Irene (Barcelona Institute of Science and Technology (BIST))
Mycoplasma pneumoniae (MPN) i s a bacterial pathogen that primarily causes atypical pneumonia. It cannot synthesize certain essential lipids and therefore relies on the host for their acquisition to survive. [...]
2025 - 10.1038/s41467-025-66129-5
Nature communications, Vol. 16 (December 2025) , art. 11159
|
|
2026-04-21
18:12 |
|
10 p, 11.9 MB |
Biomimetic Protein Materials for Adjuvant-Free Dermal Penetration
/
de Pinho Favaro, Marianna T. (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Voltà-Durán, Eric (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Sanchez, Julieta M. (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Escribano-Ferrer, Elvira (Universitat de Barcelona. Institut de Nanociència i Nanotecnologia) ;
Huaca, Vanesa (Institut de Recerca Sant Pau) ;
Miranda-Tovar, Eva (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Unzueta Elorza, Ugutz (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Parladé Molist, Eloi (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Vázquez Gómez, Esther (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Mangues, Ramon 1957- (Institut de Recerca Sant Pau) ;
Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Casanova Rigat, Isolda (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
The effective dermal delivery of functional proteins could substantially improve therapeutic options for common skin disorders, in which current lipid-based or invasive strategies face efficacy and safety limitations. [...]
2026 - 10.1021/acsmaterialslett.5c01250
ACS materials letters, Vol. 8, Num. 4 (April 2026) , p. 1045-1054
|
|
|
|
visitant ::
identificació
Estadístiques d'ús
Els més consultats
