2026-04-07
14:23 |
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2026-04-07
12:12 |
Policy Challenges in Ultra-Rare Cancers : Ethical, Social, and Legal Implications of Melanoma Prevention and Diagnosis in Children, Adolescents, and Young Adults
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Refolo, Pietro (Research Centre for Clinical Bioethics & Medical Humanities, Università Cattolica del Sacro Cuore, 00168 Rome, Italy) ;
Raimondi, Costanza (Research Centre for Clinical Bioethics & Medical Humanities, Università Cattolica del Sacro Cuore, 00168 Rome, Italy) ;
Battaglia, Livio (National Agency for Regional Health Services (AGENAS), 00187 Rome, Italy; (L.B.); (A.L.S.); (M.M.)) ;
Borras, Josep M. (Department of Clinical Sciences, University of Barcelona, 08036 Barcelona, Spain) ;
Closa, Paula (Fundació de Recerca Clínic Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, 08036 Barcelona, Spain; (S.M.L.); (L.S.-C.)) ;
Lo Scalzo, Alessandra (National Agency for Regional Health Services (AGENAS), 00187 Rome, Italy; (L.B.); (A.L.S.); (M.M.)) ;
Marchetti, Marco (National Agency for Regional Health Services (AGENAS), 00187 Rome, Italy; (L.B.); (A.L.S.); (M.M.)) ;
López, Sonia Muñoz (Fundació de Recerca Clínic Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, 08036 Barcelona, Spain; (S.M.L.); (L.S.-C.)) ;
Perez, Joan Prades (Health Department, University of Barcelona, 08036 Barcelona, Spain) ;
Sampietro-Colom, Laura (Fundació de Recerca Clínic Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, 08036 Barcelona, Spain; (S.M.L.); (L.S.-C.)) ;
Sacchini, Dario (Research Centre for Clinical Bioethics & Medical Humanities, Università Cattolica del Sacro Cuore, 00168 Rome, Italy)
Background: The ultra-rare nature of melanoma in children, adolescents, and young adults poses significant challenges to the development and implementation of effective prevention and diagnostic strategies. [...]
2025 -  10.3390/healthcare13030321
Healthcare, Vol. 13 (February 2025), art. 321
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2026-04-07
12:12 |
Policy Challenges in Ultra-Rare Cancers : Ethical, Social, and Legal Implications of Melanoma Prevention and Diagnosis in Children, Adolescents, and Young Adults
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Refolo, Pietro (Research Centre for Clinical Bioethics & Medical Humanities, Università Cattolica del Sacro Cuore, 00168 Rome, Italy) ;
Raimondi, Costanza (Research Centre for Clinical Bioethics & Medical Humanities, Università Cattolica del Sacro Cuore, 00168 Rome, Italy) ;
Battaglia, Livio (National Agency for Regional Health Services (AGENAS), 00187 Rome, Italy; (L.B.); (A.L.S.); (M.M.)) ;
Borras, Josep M. (Department of Clinical Sciences, University of Barcelona, 08036 Barcelona, Spain) ;
Closa, Paula (Fundació de Recerca Clínic Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, 08036 Barcelona, Spain; (S.M.L.); (L.S.-C.)) ;
Lo Scalzo, Alessandra (National Agency for Regional Health Services (AGENAS), 00187 Rome, Italy; (L.B.); (A.L.S.); (M.M.)) ;
Marchetti, Marco (National Agency for Regional Health Services (AGENAS), 00187 Rome, Italy; (L.B.); (A.L.S.); (M.M.)) ;
López, Sonia Muñoz (Fundació de Recerca Clínic Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, 08036 Barcelona, Spain; (S.M.L.); (L.S.-C.)) ;
Perez, Joan Prades (Health Department, University of Barcelona, 08036 Barcelona, Spain) ;
Sampietro-Colom, Laura (Fundació de Recerca Clínic Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, 08036 Barcelona, Spain; (S.M.L.); (L.S.-C.)) ;
Sacchini, Dario (Research Centre for Clinical Bioethics & Medical Humanities, Università Cattolica del Sacro Cuore, 00168 Rome, Italy)
Background: The ultra-rare nature of melanoma in children, adolescents, and young adults poses significant challenges to the development and implementation of effective prevention and diagnostic strategies. [...]
2025 - 10.3390/healthcare13030321
Healthcare, Vol. 13 (February 2025), art. 321
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2026-04-07
12:12 |
Mental Health-Related Work Disabilities During the COVID-19 Lockdown in Spain : A Retrospective Analysis
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Gutiérrez Naharro, Eva María (Nursing Department, Faculty of Nursing, Physiotherapy and Podiatry, University of Seville, 41009 Seville, Spain) ;
Fernández-Sáez, José (Servei Atenció Primaria Terres de l'Ebre, Institut Català de la Salut, 43500 Tarragona, Spain) ;
Sillero-Sillero, Amalia (Escola Universitària Gimbernat, Adscrita a Universitat Autònoma de Barcelona, 08174 Sant Cugat, Spain) ;
Tolo Espinet, Pau (Mutua Intercomarcal, 08242 Manresa, Spain) ;
Ponce Blandón, José Antonio (Nursing Department, Faculty of Nursing, Physiotherapy and Podiatry, University of Seville, 41009 Seville, Spain)
Background: The COVID-19 lockdown posed unprecedented psychological challenges worldwide. In Spain, Mutual Collaborators with Social Security manage work-related disabilities, including mental health cases. [...]
2025 - 10.3390/healthcare13030236
Healthcare, Vol. 13 (January 2025), art. 236
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2026-04-07
12:12 |
Prenatal and Perinatal Factors Associated with Infant Acute Lymphoblastic Leukaemia : A Scoping Review
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Sanvisens, Arantza (Descriptive Epidemiology, Genetics, and Cancer Prevention Group, Josep Carreras Leukaemia Research Institute, 17004 Girona, Spain) ;
Bueno, Clara (Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Instituto de Salud Carlos III (ISCIII), 08028 Barcelona, Spain) ;
Calvete, Oriol (Myelodysplastic Syndrome Group, Josep Carreras Leukaemia Research Institute, ICO-Hospital Germans Trias i Pujol, Universitat Autònoma de Barcelona, 08193 Barcelona, Spain (F.S.)) ;
Sole, F. (Myelodysplastic Syndrome Group, Josep Carreras Leukaemia Research Institute, ICO-Hospital Germans Trias i Pujol, Universitat Autònoma de Barcelona, 08193 Barcelona, Spain (F.S.)) ;
Marcos-Gragera, Rafael (CIBER of Epidemiology and Public Health (CIBERESP), 28029 Madrid, Spain) ;
Solans, Marta (Research Group on Statistics, Econometrics and Health (GRECS), University of Girona, 17004 Girona, Spain)
This scoping review provides an overview of the few observational studies that have investigated potential risk factors for acute lymphoblastic leukaemia in infants. It summarises some well-established associations in the literature, such as maternal exposure to pesticides and high birth weight, and outlines suggestive associations, such as heavy parental smoking, parental use of multiple medications, and maternal exposure to air pollution during pregnancy, that merit further research. [...]
2025 - 10.3390/cancers17030370
Cancers, Vol. 17 (January 2025), art. 370
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2026-04-07
11:12 |
Improving Sensitivity and Resolution of Dendrimer Identification in MALDI-TOF Mass Spectrometry Using Varied Matrix Combinations
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Sanhueza, Claudia (Escuela de Ingeniería, Facultad de Ciencias, Ingeniería y Tecnología, Universidad Mayor, Temuco 4780000, Chile) ;
Dias, Nathalia Baptista (Scientific and Technological Bioresource Nucleus (BIOREN-UFRO), Universidad de La Frontera, Temuco 4811230, Chile) ;
Vergara, Daniela (Centro de Excelencia en Medicina Traslacional (CEMT), Facultad de Medicina, Universidad de La Frontera, Temuco 4811230, Chile) ;
Silva, Lisette (Carrera de Química y Farmacia, Facultad de Medicina, Universidad de La Frontera, Temuco 4811230, Chile) ;
Chávez Ángel, Emigdio (Catalan Institute of Nanoscience and Nanotechnology, CSIC and BIST, Campus UAB, 08193 Bellaterra, Barcelona, Spain) ;
Castro-Alvarez, Alejandro (Departamento de Ciencias Preclínicas, Facultad de Medicina, Universidad de La Frontera, Temuco 4811230, Chile)
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) is a well-known technique for polymer analysis, particularly for determining the molecular weight and structural details of dendrimers. [...]
2025 - 10.3390/polym17020219
Polymers, Vol. 17 (January 2025), art. 219
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2026-04-07
11:12 |
Improving Sensitivity and Resolution of Dendrimer Identification in MALDI-TOF Mass Spectrometry Using Varied Matrix Combinations
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Sanhueza, Claudia (Escuela de Ingeniería, Facultad de Ciencias, Ingeniería y Tecnología, Universidad Mayor, Temuco 4780000, Chile) ;
Dias, Nathalia Baptista (Scientific and Technological Bioresource Nucleus (BIOREN-UFRO), Universidad de La Frontera, Temuco 4811230, Chile) ;
Vergara, Daniela (Centro de Excelencia en Medicina Traslacional (CEMT), Facultad de Medicina, Universidad de La Frontera, Temuco 4811230, Chile) ;
Silva, Lisette (Carrera de Química y Farmacia, Facultad de Medicina, Universidad de La Frontera, Temuco 4811230, Chile) ;
Chávez Ángel, Emigdio (Catalan Institute of Nanoscience and Nanotechnology, CSIC and BIST, Campus UAB, 08193 Bellaterra, Barcelona, Spain) ;
Castro-Alvarez, Alejandro (Departamento de Ciencias Preclínicas, Facultad de Medicina, Universidad de La Frontera, Temuco 4811230, Chile)
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) is a well-known technique for polymer analysis, particularly for determining the molecular weight and structural details of dendrimers. [...]
2025 - 10.3390/polym17020219
Polymers, Vol. 17 (January 2025), art. 219
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2026-04-07
11:12 |
The modulating effect of circulating carbohydrate antigen 125 on ST2 and long-term recurrent morbidity burden
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Revuelta-López, Elena (CIBER Cardiovascular) ;
De la Espriella, Rafael (Hospital Clínico Universitario, INCLIVA. Universitat de València. Cardiology Department) ;
Miñana, Gema (Hospital Clínico Universitario, INCLIVA. Universitat de València. Cardiology Department) ;
Santas, Enrique (Hospital Clínico Universitario, INCLIVA. Universitat de València. Cardiology Department) ;
Villar, Sandra (Hospital Clínico Universitario, INCLIVA. Universitat de València. Cardiology Department) ;
Sanchis, Juan (Hospital Clínico Universitario, INCLIVA. Universitat de València. Cardiology Department) ;
Bayés-Genís, Antoni (CIBER Cardiovascular) ;
Núñez, Julio (Hospital Clínico Universitario, INCLIVA. Universitat de València. Cardiology Department)
The online version contains supplementary material available at 10. 1038/s41598-024-84622-7.
2025 - 10.1038/s41598-024-84622-7
Scientific reports, Vol. 15 (January 2025), art. 1905
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2026-04-07
11:12 |
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2026-04-07
11:12 |
Predictive biophysical neural network modeling of a compendium of in vivo transcription factor DNA binding profiles for Escherichia coli
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Lally, Patrick (Cummington Mall. Department of Biomedical Engineering, Boston University) ;
Gómez-Romero, Laura (Ciudad de México. Escuela de Medicina y Ciencias de la Salud, Tecnológico de Monterrey) ;
Tierrafría, Víctor H. (Cuernavaca. Centro de Ciencias Genómicas, Universidad Nacional Autónoma de México, Avenida Universidad s/n) ;
Aquino, Patricia (Cummington Mall. Department of Biomedical Engineering, Boston University) ;
Rioualen, Claire (Cuernavaca. Centro de Ciencias Genómicas, Universidad Nacional Autónoma de México, Avenida Universidad s/n) ;
Zhang, Xiaoman (Cummington Mall. Department of Biomedical Engineering, Boston University) ;
Kim, Sunyoung (Regina. Department of Biochemistry, University of Regina) ;
Baniulyte, Gabriele (New York State Department of Health. Wadsworth Center) ;
Plitnick, Jonathan (New York State Department of Health. Wadsworth Center) ;
Smith, Carol (New York State Department of Health. Wadsworth Center) ;
Babu, Mohan (Regina. Department of Biochemistry, University of Regina) ;
Collado-Vides, Julio (Universitat Pompeu Fabra (UPF). Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Dr. Aiguader 88, Barcelona 08003) ;
Wade, Joseph T. (SUNY. Department of Biomedical Sciences, University at Albany) ;
Galagan, James E. (Cummington Mall. Bioinformatics Program, Boston University)
The DNA binding of most Escherichia coli Transcription Factors (TFs) has not been comprehensively mapped, and few have models that can quantitatively predict binding affinity. We report the global mapping of in vivo DNA binding for 139 E. [...]
2025 - 10.1038/s41467-025-58862-8
Nature communications, Vol. 16 (May 2025), art. 4255
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