b8557fac349f30698b21053061e0a3fe  Vega_Alari_et_al._ICB_10_merged_ACCEPTED_VERSION.pdf
15bfbe25d95d4f4bb5fa4aab1b2c0cdbf6689522  Vega_Alari_et_al._ICB_10_merged_ACCEPTED_VERSION.pdf
80709c5126bcba86cc7e04eaea382431249eb63ec6d044e141dcddba257a4d87  Vega_Alari_et_al._ICB_10_merged_ACCEPTED_VERSION.pdf

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     Item: 
      Title: Running title: CD69 limits immune response to infection
     Item: 
      Title: Summary
     Item: 
      Title: Key words: Bacterial Infection; Knockout; Rodent; T Cells
     Item: 
      Title: Introduction
     Item: 
      Title: Material and methods
     Item: 
      Title: Mice
     Item: 
      Title: In vivo experiments
     Item: 
      Title: Flow cytometry
     Item: 
      Title: Adoptive transfer experiments.
     Item: 
      Title: Ex vivo Lm infection
     Item: 
      Title: Quantitative real-time RT-PCR analyses
     Item: 
      Title: Cell death assays
     Item: 
      Title: Statistical analysis
     Item: 
      Title: Results
     Item: 
      Title: Major leukocyte populations are not altered in Lm-infected CD69-/- mice
     Item: 
      Title: Increased expression of Th1 cytokines in infected CD69-/- splenocytes
     Item: 
      Title: Increased tissue damage in infected CD69-/- mice
     Item: 
      Title: Increased susceptibility of CD69-/- mice to Lm infection
     Item: 
      Title: Augmented innate response but defective specific response in infected CD69-/- mice.
      Children: 
       Item: 
        Title: Discussion
     Item: 
      Title: In our study, the CD69-/- T cells, under the observed higher IFN/ levels, might be exposed to increased activating signals, probably reflected by the observed increased IFN production by CD8+ T cells. In this CD8+ T cells, the INF production at su...
     Item: 
      Title: Acknowledgments
     Item: 
      Title: Figure 1. Similar intracellular growth of Lm in WT and CD69-/- myeloid cells.
     Item: 
      Title: Figure 6. Adaptive versus innate response contribution to response to Lm infection in CD69-/- mice. (A) CD69 deficiency does not impair the innate immune response to Lm in RAG2-/- mice. RAG2-/- CD69 +/+ and CD69-/-  mice in Balb/c background were infe...
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      Title: Número de diapositiva 1
     Item: 
      Title: Número de diapositiva 2
     Item: 
      Title: Número de diapositiva 3
     Item: 
      Title: Número de diapositiva 4
     Item: 
      Title: Número de diapositiva 5
     Item: 
      Title: Número de diapositiva 6
     Item: 
      Title: Número de diapositiva 7
     Item: 
      Title: Número de diapositiva 1
     Item: 
      Title: Número de diapositiva 2
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