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Title: Background Destination: SecB2 Item: Title: Methods and results Destination: SecB3 Item: Title: Conclusions Destination: SecB4 Item: Title: Background Destination: SecA5 Item: Title: Methods Destination: SecA6 Children: Item: Title: Animals Destination: SecB7 Item: Title: Metabolic analyses Destination: SecB8 Item: Title: Echocardiography Destination: SecB9 Item: Title: Myocardial perfusion Destination: SecB10 Item: Title: Histology Destination: SecB11 Item: Title: Electron microscopy Destination: SecB12 Item: Title: Statistical analysis Destination: SecB13 Item: Title: Results Destination: SecA14 Children: Item: Title: Basic metabolic parameters Destination: SecB15 Item: Title: Atherosclerosis in hypercholesterolemic mice is accompanied by compensatory vascular remodeling and aggravated by calcification in IGF-II/LDLR-/-ApoB100/100 mice Destination: SecB16 Item: Title: Severe coronary artery stenosis in hypercholesterolemic mice Destination: SecB17 Item: Title: Coronary atherosclerosis leads to left ventricular dysfunction Destination: SecB18 Item: Title: Cardiac reserve is preserved but reduced in atherosclerotic mice Destination: SecB19 Item: Title: Myocardial perfusion correlates with the atherosclerotic burden Destination: SecB20 Item: Title: Ultrastructural analysis of myocardium reveals degenerative changes in hypercholesterolemic mice Destination: SecB21 Item: Title: Discussion Destination: SecA22 Item: Title: Conclusions Destination: SecA23 Item: Title: Acknowledgements Destination: SecA24 Item: Title: Author details Destination: SecA25 Item: Title: Authors' contributions Destination: SecA26 Item: Title: Competing interests Destination: SecA27 Item: Title: References Destination: SecA28 Info: Title: Left ventricular dysfunction with reduced functional cardiac reserve in diabetic and non-diabetic LDL-receptor deficient apolipoprotein B100-only mice Author: Suvi E Heinonen Subject: Cardiovascular Diabetology 2011, 10:59. 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Encoding: WinAnsiEncoding XMP: Acrobat Distiller 9.4.2 (Windows) 2011-07-15T22:44:27+05:30 2011-07-16T00:41:46+05:30 2011-07-16T00:41:46+05:30 Arbortext Advanced Print Publisher 10.0.1082/W Unicode Cardiovascular Diabetology 2011, 10:59. doi:10.1186/1475-2840-10-59 application/pdf http://dx.doi.org/10.1186/1475-2840-10-59 Suvi E Heinonen Mari Merentie Marja Hedman Petri I Mäkinen Elina Loponen Ivana Kholová Fatima Bosch Markku Laakso Seppo Ylä-Herttuala Left ventricular dysfunction with reduced functional cardiac reserve in diabetic and non-diabetic LDL-receptor deficient apolipoprotein B100-only mice Cardiovascular Diabetology 2011, 10:59. doi:10.1186/1475-2840-10-59 BioMed Central Ltd 2011-06-30 © 2011 Heinonen et al; licensee BioMed Central Ltd. uuid:7f461dff-335f-4446-86f0-394396d965b2 uuid:18f15e37-67fb-40b5-8df5-b2b97bfd4125 True http://www.cardiab.com/content/10/1/59 10.1186/1475-2840-10-59 59 59 © 2011 Heinonen et al; licensee BioMed Central Ltd. 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455, 605 Annotation: Subtype: Link Rect: 402, 571, 514, 579 Annotation: Subtype: Link Rect: 319, 562, 535, 570 Annotation: Subtype: Link Rect: 319, 553, 451, 561 Annotation: Subtype: Link Rect: 469, 535, 535, 543 Annotation: Subtype: Link Rect: 319, 526, 522, 534 Annotation: Subtype: Link Rect: 319, 517, 335, 525 Annotation: Subtype: Link Rect: 484, 508, 534, 516 Annotation: Subtype: Link Rect: 319, 499, 470, 507 Annotation: Subtype: Link Rect: 386, 472, 537, 480 Annotation: Subtype: Link Rect: 319, 464, 520, 471 Annotation: Subtype: Link Rect: 319, 455, 519, 462 Annotation: Subtype: Link Rect: 319, 446, 444, 453 Annotation: Subtype: Link Rect: 319, 428, 538, 435 Annotation: Subtype: Link Rect: 415, 410, 536, 417 Annotation: Subtype: Link Rect: 319, 401, 531, 408 Annotation: Subtype: Link Rect: 319, 392, 396, 399 Annotation: Subtype: Link Rect: 478, 383, 524, 390 Annotation: Subtype: Link Rect: 319, 374, 517, 381 Annotation: Subtype: Link Rect: 319, 365, 369, 372 Annotation: Subtype: Link Rect: 319, 347, 530, 354 Annotation: Subtype: Link Rect: 319, 338, 380, 345 Annotation: Subtype: Link Rect: 431, 320, 528, 328 Annotation: Subtype: Link Rect: 319, 311, 530, 319 Annotation: Subtype: Link Rect: 319, 302, 381, 310 Annotation: Subtype: Link Rect: 437, 293, 537, 301 Annotation: Subtype: Link Rect: 319, 284, 484, 292 Annotation: Subtype: Link Rect: 396, 257, 536, 265 Annotation: Subtype: Link Rect: 319, 248, 511, 256 Annotation: Subtype: Link Rect: 319, 239, 411, 247 Annotation: Subtype: Link Rect: 350, 230, 502, 238 Annotation: Subtype: Link Rect: 319, 221, 534, 229 Annotation: Subtype: Link Rect: 319, 212, 403, 220 Annotation: Subtype: Link Rect: 482, 195, 521, 202 Annotation: Subtype: Link Rect: 319, 186, 537, 193 Annotation: Subtype: Link Rect: 319, 177, 526, 184 Annotation: Subtype: Link Rect: 319, 168, 343, 175 Annotation: Subtype: Link Rect: 501, 159, 529, 166 Annotation: Subtype: Link Rect: 319, 150, 504, 157 Page: Label: 12 Annotations: Annotation: Subtype: Link Rect: 124, 697, 274, 704 Annotation: Subtype: Link Rect: 71, 661, 283, 668 Annotation: Subtype: Link Rect: 71, 652, 267, 659 Annotation: Subtype: Link Rect: 71, 643, 94, 650 Annotation: Subtype: Link Rect: 97, 625, 275, 632 Annotation: Subtype: Link Rect: 71, 616, 260, 623 Annotation: Subtype: Link Rect: 71, 607, 146, 614 Checksum: f7d96c37 Type: CRC32 Checksum: 3dc39a44fc25b7b0e2bde79066d8c28f Type: MD5 Checksum: 07cbc6b71c5307c69e9a14d6e2d30c27ff27869f Type: SHA-1 Checksum: f1ccd606cd245fc13b1b476cf6fcd6944d617f90a8b3042c8f0e46880ab850b1 Type: SHA-256