660149012d060c4e58cd4b45b2cc78ac  bmcneurology_a2012m9v12n103.pdf
cc131c08ca160fb47ae9e58490d58ccd8ce6981b  bmcneurology_a2012m9v12n103.pdf
74f14ae1fed1b17d5a1080e42f4c887fd7872baf8f4f24ea8bda03b586049c6f  bmcneurology_a2012m9v12n103.pdf

Title:          Regulatory role of vitamin D in T-cell reactivity against myelin peptides in relapsing-remitting multiple sclerosis patients
Creator:        Arbortext Advanced Print Publisher 9.1.440/W Unicode
Producer:       Acrobat Distiller 10.0.0 (Windows)
CreationDate:   Mon Oct  8 15:50:17 2012
ModDate:        Mon Oct  8 15:50:44 2012
Tagged:         no
Pages:          6
Encrypted:      no
Page size:      595.276 x 793.701 pts
File size:      274600 bytes
Optimized:      yes
PDF version:    1.3

name                                 type              emb sub uni object ID
------------------------------------ ----------------- --- --- --- ---------
OHLJBC+AdvTTaf7f9f4f.B               Type 1C           yes yes no     205  0
OHLJBD+AdvTTe45e47d2                 Type 1C           yes yes no     206  0
OHLJCD+AdvTTb5929f4c                 Type 1C           yes yes no     207  0
OHLJCE+AdvTT99c4c969                 Type 1C           yes yes no     208  0
OHLJCF+AdvTT86d47313                 Type 1C           yes yes no     209  0
OHLKAB+AdvTT7329fd89.I               Type 1C           yes yes no     210  0
OHLKDE+AdvTT86d47313+22              Type 1C           yes yes yes     13  0
OHLKBC+AdvTT86d47313+20              Type 1C           yes yes no      77  0
OHLKCC+AdvTT5843c571+21              Type 1C           yes yes no      12  0
OHLKDD+AdvTT86d47313+03              Type 1C           yes yes yes     14  0
OHLKFE+AdvTT8861b38f.I               Type 1C           yes yes no      78  0
OHLKGF+AdvTTb5929f4c+20              Type 1C           yes yes no      79  0
OHLPJG+AdvTT99c4c969+20              Type 1C           yes yes no      68  0
OHLPKH+AdvTT1b53b5fb.I               Type 1C           yes yes no      69  0
OHLPKI+AdvTT1b53b5fb.I+20            Type 1C           yes yes no      70  0

Jhove (Rel. 1.4, 2009-07-30)
 Date: 2013-10-25 22:52:48 GMT+01:00
 RepresentationInformation: bmcneurology_a2012m9v12n103.pdf
  ReportingModule: PDF-hul, Rel. 1.8 (2009-05-22)
  LastModified: 2013-10-25 13:47:50 GMT+01:00
  Size: 274600
  Format: PDF
  Version: 1.3
  Status: Well-Formed and valid
  SignatureMatches:
   PDF-hul
  MIMEtype: application/pdf
  Profile: Linearized PDF
  PDFMetadata: 
   Objects: 224
   FreeObjects: 1
   IncrementalUpdates: 1
   DocumentCatalog: 
    PageLayout: SinglePage
    PageMode: UseNone
    Outlines: 
     Item: 
      Title: Abstract
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6019d0a1
      Children: 
       Item: 
        Title: Background
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@3ed02b51
       Item: 
        Title: Methods
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@54cbf30e
       Item: 
        Title: Results
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@19c247a0
       Item: 
        Title: Conclusions
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@21ec6696
     Item: 
      Title: Background
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@27431340
     Item: 
      Title: Methods
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@24a4e2e3
      Children: 
       Item: 
        Title: Patients
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@452bb7e0
       Item: 
        Title: Protocol variables
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@3934f69a
       Item: 
        Title: Blood samples
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@442a15cd
       Item: 
        Title: Statistical analysis
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@26fd68b1
     Item: 
      Title: Results
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@46e45076
      Children: 
       Item: 
        Title: Clinical characteristics of subjects
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@375e9756
       Item: 
        Title: Plasma 25(OH) D concentrations between MS patients and HC
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2321ab80
       Item: 
        Title: Association between plasma 25(OH)D concentrations and demographic, clinical, radiological and immunological disease characteristics in the MS cohort
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@77827284
     Item: 
      Title: Discussion
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@152c7568
     Item: 
      Title: Conclusions
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@19d009b4
     Item: 
      Title: Competing interests
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@292d15a9
     Item: 
      Title: Authors´ contributions
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4ee91f5d
     Item: 
      Title: Acknowledgements
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2b0a3b24
     Item: 
      Title: Author details
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2cb0ce8f
     Item: 
      Title: References
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@bc92535
   Info: 
    Title: Regulatory role of vitamin D in T-cell reactivity against myelin peptides in relapsing-remitting multiple sclerosis patients
    Creator: Arbortext Advanced Print Publisher 9.1.440/W Unicode
    Producer: Acrobat Distiller 10.0.0 (Windows)
    CreationDate: Mon Oct 08 08:50:17 GMT+01:00 2012
    ModDate: Mon Oct 08 08:50:44 GMT+01:00 2012
   ID: 0xbf6bd2e68ebded06b952b1e2448e999f, 0xdb64b648b216fabe88aea6a3feec09a0
   Filters: 
    FilterPipeline: FlateDecode
    FilterPipeline: DCTDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      MIMEType: application/pdf
      ColorSpace: black is zero
      ImageWidth: 897
      ImageLength: 863
      BitsPerSample: 8
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      MIMEType: application/pdf
      CompressionScheme: JPEG
      ColorSpace: black is zero
      ImageWidth: 897
      ImageLength: 936
      BitsPerSample: 8
   Fonts: 
    Type1: 
     Font: 
      BaseFont: OHLPJG+AdvTT99c4c969+20
      FontSubset: true
      FirstChar: 146
      LastChar: 146
      FontDescriptor: 
       FontName: OHLPJG+AdvTT99c4c969+20
       Flags: Nonsymbolic
       FontBBox: -218, -197, 1583, 864
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: OHLKAB+AdvTT7329fd89.I
      FontSubset: true
      FirstChar: 40
      LastChar: 121
      FontDescriptor: 
       FontName: OHLKAB+AdvTT7329fd89.I
       Flags: Nonsymbolic
       FontBBox: -218, -250, 885, 864
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: OHLKGF+AdvTTb5929f4c+20
      FontSubset: true
      FirstChar: 146
      LastChar: 151
      FontDescriptor: 
       FontName: OHLKGF+AdvTTb5929f4c+20
       Flags: Nonsymbolic
       FontBBox: -218, -208, 1375, 864
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: OHLJCD+AdvTTb5929f4c
      FontSubset: true
      FirstChar: 37
      LastChar: 243
      FontDescriptor: 
       FontName: OHLJCD+AdvTTb5929f4c
       Flags: Nonsymbolic
       FontBBox: -41, -250, 812, 864
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: OHLJCF+AdvTT86d47313
      FontSubset: true
      FirstChar: 37
      LastChar: 177
      FontDescriptor: 
       FontName: OHLJCF+AdvTT86d47313
       Flags: Serif, Nonsymbolic
       FontBBox: -218, -239, 1020, 875
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: OHLJCE+AdvTT99c4c969
      FontSubset: true
      FirstChar: 37
      LastChar: 121
      FontDescriptor: 
       FontName: OHLJCE+AdvTT99c4c969
       Flags: Nonsymbolic
       FontBBox: -41, -250, 854, 885
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: OHLKCC+AdvTT5843c571+21
      FontSubset: true
      FirstChar: 153
      LastChar: 153
      FontDescriptor: 
       FontName: OHLKCC+AdvTT5843c571+21
       Flags: Nonsymbolic
       FontBBox: 0, -302, 958, 708
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: OHLJBC+AdvTTaf7f9f4f.B
      FontSubset: true
      FirstChar: 40
      LastChar: 121
      FontDescriptor: 
       FontName: OHLJBC+AdvTTaf7f9f4f.B
       Flags: Nonsymbolic
       FontBBox: -218, -250, 875, 895
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: OHLKDE+AdvTT86d47313+22
      FontSubset: true
      FirstChar: 1
      LastChar: 138
      FontDescriptor: 
       FontName: OHLKDE+AdvTT86d47313+22
       Flags: Symbolic
       FontBBox: -166, -270, 1031, 906
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: OHLKBC+AdvTT86d47313+20
      FontSubset: true
      FirstChar: 146
      LastChar: 150
      FontDescriptor: 
       FontName: OHLKBC+AdvTT86d47313+20
       Flags: Nonsymbolic
       FontBBox: -218, -218, 1291, 812
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: OHLPKI+AdvTT1b53b5fb.I+20
      FontSubset: true
      FirstChar: 146
      LastChar: 146
      FontDescriptor: 
       FontName: OHLPKI+AdvTT1b53b5fb.I+20
       Flags: Nonsymbolic
       FontBBox: -218, -197, 1333, 822
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: OHLJBD+AdvTTe45e47d2
      FontSubset: true
      FirstChar: 40
      LastChar: 243
      FontDescriptor: 
       FontName: OHLJBD+AdvTTe45e47d2
       Flags: Nonsymbolic
       FontBBox: -218, -250, 833, 875
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: OHLKFE+AdvTT8861b38f.I
      FontSubset: true
      FirstChar: 85
      LastChar: 118
      FontDescriptor: 
       FontName: OHLKFE+AdvTT8861b38f.I
       Flags: Nonsymbolic
       FontBBox: -187, -239, 1062, 875
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: OHLKDD+AdvTT86d47313+03
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: OHLKDD+AdvTT86d47313+03
       Flags: Symbolic
       FontBBox: -135, -250, 906, 822
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: OHLPKH+AdvTT1b53b5fb.I
      FontSubset: true
      FirstChar: 46
      LastChar: 121
      FontDescriptor: 
       FontName: OHLPKH+AdvTT1b53b5fb.I
       Flags: Nonsymbolic
       FontBBox: -114, -250, 864, 854
       FontFile3: true
      Encoding: WinAnsiEncoding
   XMP: <x:xmpmeta xmlns:x="adobe:ns:meta/"
           x:xmptk="Adobe XMP Core 4.2.1-c043 52.372728, 2009/01/18-15:08:04">
   <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
      <rdf:Description xmlns:xmp="http://ns.adobe.com/xap/1.0/" rdf:about="">
         <xmp:Label>BMC Neurology 2012, 12:1. doi:10.1186/1471-2377-12-103</xmp:Label>
      </rdf:Description>
      <rdf:Description xmlns:dc="http://purl.org/dc/elements/1.1/" rdf:about="">
         <dc:format>application/pdf</dc:format>
         <dc:identifier>http://dx.doi.org/10.1186/1471-2377-12-103</dc:identifier>
         <dc:creator>
            <rdf:Seq>
               <rdf:li>Laia Grau-L�pez</rdf:li>
               <rdf:li>Maria Luisa Granada</rdf:li>
               <rdf:li>D�lia Ra�ch-Regu�</rdf:li>
               <rdf:li>Mar Naranjo-G�mez</rdf:li>
               <rdf:li>Francesc E Borr�s-Serres</rdf:li>
               <rdf:li>Eva Mart�nez-C�ceres</rdf:li>
               <rdf:li>Cristina Ramo-Tello</rdf:li>
            </rdf:Seq>
         </dc:creator>
         <dc:title>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Regulatory role of vitamin D in T-cell reactivity against myelin peptides in relapsing-remitting multiple sclerosis patients</rdf:li>
            </rdf:Alt>
         </dc:title>
         <dc:description>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">BMC Neurology 2012, 12:1. doi:10.1186/1471-2377-12-103</rdf:li>
            </rdf:Alt>
         </dc:description>
         <dc:publisher>
            <rdf:Bag>
               <rdf:li>BMC Neurology</rdf:li>
            </rdf:Bag>
         </dc:publisher>
         <dc:date>
            <rdf:Seq>
               <rdf:li>2012-09-24</rdf:li>
            </rdf:Seq>
         </dc:date>
         <dc:rights>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">� 2012 Grau-L�pez et al.; licensee BioMed Central Ltd.</rdf:li>
            </rdf:Alt>
         </dc:rights>
         <dc:subject>
            <rdf:Bag>
               <rdf:li>Multiple sclerosis</rdf:li>
               <rdf:li>T-cell proliferation</rdf:li>
               <rdf:li>Vitamin D</rdf:li>
            </rdf:Bag>
         </dc:subject>
      </rdf:Description>
      <rdf:Description xmlns:xmpRights="http://ns.adobe.com/xap/1.0/rights/" rdf:about="">
         <xmpRights:Marked>True</xmpRights:Marked>
      </rdf:Description>
      <rdf:Description xmlns:prism="http://prismstandard.org/namespaces/basic/2.0/" rdf:about="">
         <prism:url>BMC Neurology</prism:url>
         <prism:doi>10.1186/1471-2377-12-103</prism:doi>
         <prism:pageRange>1</prism:pageRange>
         <prism:startingPage>1</prism:startingPage>
         <prism:endingPage>1</prism:endingPage>
         <prism:copyright>� 2012 Grau-L�pez et al.; licensee BioMed Central Ltd.</prism:copyright>
         <prism:publicationName>BMC Neurology</prism:publicationName>
         <prism:aggregationType>journal</prism:aggregationType>
         <prism:volume>12</prism:volume>
         <prism:rightsAgent>reprints@biomedcentral.com</prism:rightsAgent>
         <prism:publicationDate>2012-09-24</prism:publicationDate>
         <prism:number>1</prism:number>
         <prism:issueidentifier>1</prism:issueidentifier>
         <prism:issn>BMC Neurology</prism:issn>
      </rdf:Description>
   <rdf:Description rdf:about="" xmlns:pdf="http://ns.adobe.com/pdf/1.3/"><pdf:Keywords> Multiple sclerosis; T-cell proliferation; Vitamin D</pdf:Keywords></rdf:Description></rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Label: 0
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 141, 255, 146, 265
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 204, 183, 209, 193
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 211, 183, 216, 193
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 528, 279, 533, 289
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 371, 231, 376, 241
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 378, 231, 383, 241
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 424, 183, 429, 193
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 336, 123, 340, 133
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 344, 123, 354, 133
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 450, 99, 460, 109
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 114, 119, 172, 126
      Annotation: 
       Subtype: Link
       Rect: 287, 67, 403, 74
     Thumb: true
    Page: 
     Label: 1
     Sequence: 2
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 93, 670, 103, 680
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 239, 514, 249, 524
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 232, 430, 242, 440
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 427, 622, 437, 632
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 453, 190, 463, 200
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 481, 154, 491, 164
       Destination: 61
     Thumb: true
    Page: 
     Label: 2
     Sequence: 3
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 92, 235, 97, 244
       Destination: 25
      Annotation: 
       Subtype: Link
       Rect: 398, 467, 403, 477
       Destination: 25
     Thumb: true
    Page: 
     Label: 3
     Sequence: 4
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 158, 514, 163, 524
       Destination: 34
      Annotation: 
       Subtype: Link
       Rect: 474, 622, 479, 632
       Destination: 42
      Annotation: 
       Subtype: Link
       Rect: 487, 455, 497, 465
       Destination: 61
     Thumb: true
    Page: 
     Label: 4
     Sequence: 5
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 280, 346, 285, 356
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 96, 298, 106, 308
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 210, 262, 220, 272
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 216, 178, 221, 188
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 224, 178, 234, 188
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 307, 562, 317, 572
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 325, 418, 335, 428
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 454, 394, 459, 404
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 340, 298, 345, 308
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 382, 262, 392, 272
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 523, 214, 533, 224
       Destination: 61
      Annotation: 
       Subtype: Link
       Rect: 307, 178, 317, 188
       Destination: 61
     Thumb: true
    Page: 
     Label: 5
     Sequence: 6
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 319, 362, 423, 369
     Thumb: true
  Checksum: 38808972
   Type: CRC32
  Checksum: 660149012d060c4e58cd4b45b2cc78ac
   Type: MD5
  Checksum: cc131c08ca160fb47ae9e58490d58ccd8ce6981b
   Type: SHA-1