00a174dced97c4b23dde8b26083300a5 genint_a2012m9v3n6.pdf fe1d24142e9c1f7403a789f6ecac61ed12fe5685 genint_a2012m9v3n6.pdf effde237fec45f9c8a79f848670ec48ca14576ada55d3601ed3225b72a6117ba genint_a2012m9v3n6.pdf Title: Dysfunctional telomeres in primary cells from Fanconi anemia FANCD2 patients Creator: Arbortext Advanced Print Publisher 9.1.440/W Unicode Producer: Acrobat Distiller 10.0.0 (Windows) CreationDate: Wed Nov 28 21:10:38 2012 ModDate: Wed Nov 28 21:15:12 2012 Tagged: no Pages: 12 Encrypted: no Page size: 595.276 x 793.701 pts File size: 1165442 bytes Optimized: yes PDF version: 1.3 name type emb sub uni object ID ------------------------------------ ----------------- --- --- --- --------- KPFEGF+AdvTTaf7f9f4f.B Type 1C yes yes no 395 0 KPFEHG+AdvTTe45e47d2 Type 1C yes yes no 396 0 KPFEHH+AdvTTb5929f4c Type 1C yes yes no 397 0 KPFEHI+AdvTT99c4c969 Type 1C yes yes no 398 0 KPFEIJ+AdvTTb5929f4c+03 Type 1C yes yes yes 399 0 KPFEIK+AdvTT86d47313 Type 1C yes yes no 400 0 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genint_a2012m9v3n6.pdf ReportingModule: PDF-hul, Rel. 1.8 (2009-05-22) LastModified: 2013-11-22 14:31:20 GMT+01:00 Size: 1165442 Format: PDF Version: 1.3 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 426 FreeObjects: 2 IncrementalUpdates: 2 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Abstract Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@24a4e2e3 Children: Item: Title: Background Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@452bb7e0 Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@3934f69a Item: Title: Conclusion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@442a15cd Item: Title: Keywords Item: Title: Background Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@26fd68b1 Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@46e45076 Children: Item: Title: Assignment of FA patients to complementation group D2 Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@375e9756 Item: Title: Telomere length analysis in FANCD2 lymphocytes by quantitative fluorescence in situ hybridization Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2321ab80 Item: Title: Effects of diepoxybutane on the incidence of sister chromatid exchange and telomere sister chromatid exchange in FANCD2 lymphocytes Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@77827284 Item: Title: Effects of ionizing radiation on apoptosis of FANCD2 leucocytes and fibroblasts Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@152c7568 Item: Title: Effects of diepoxybutane and ionizing radiation 149 on percentage of telomere dysfunction-induced foci 150 in FANCD2 fibrob Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@19d009b4 Item: Title: Relative expression of TRF1 and TRF2 mRNAs Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@292d15a9 Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4ee91f5d Item: Title: Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2b0a3b24 Children: Item: Title: Patients Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2cb0ce8f Item: Title: Cell culture Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@bc92535 Children: Item: Title: Lymphocytes Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42a9c09e Item: Title: Fibroblasts Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@16a4e743 Item: Title: Irradiation Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@244aeb52 Item: Title: Diepoxybutane treatment Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@329f671b Item: Title: Western blot analysis for the subtyping of FA patients Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7f2a3793 Item: Title: Quantitative fluorescence in situ hybridization Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2ca6d51e Item: Title: Sister chromatid exchange analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7cf1bb78 Item: Title: Chromosome orientation fluorescence in situ hybridization Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@624b035d Item: Title: TIF assay Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2aca0115 Item: Title: Apoptosis assay Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@340d1fa5 Item: Title: Isolation of RNA and quantitative real-time reverse 602 transcriptase-PCR Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4998a455 Item: Title: Statistics Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@444cee32 Item: Title: Competing interests Destination: 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doi:10.1186/2041-9414-3-6 Genome Integrity 2012-09-14 � 2012 joksic et al.; licensee BioMed Central Ltd. Primary FA cells Telomere dysfunction Expression of TRF1 and TRF2 True Genome Integrity 10.1186/2041-9414-3-6 1 1 1 � 2012 joksic et al.; licensee BioMed Central Ltd. 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