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Although radiotherapy increases survival among cancer patients, this treatment does not come without secondary effects, among which the most problematic is gonad Keywords: meiosis; oocytes; fertility; ionizing irradiation effects; radiation-sensitivity; DSBs, genome instability Author: Aurora Ruiz-Herrera 1 Creator: PScript5.dll Version 5.2 Producer: Acrobat Distiller 7.0 (Windows) CreationDate: Fri Aug 24 11:45:40 2012 ModDate: Mon Feb 29 16:10:49 2016 Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 24 Encrypted: no Page size: 595.22 x 842 pts (A4) Page rot: 0 File size: 294099 bytes Optimized: yes PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- MIEPDN+TimesNewRomanPS-ItalicMT Type 1C WinAnsi yes yes no 129 0 MIEPDO+TimesNewRomanPSMT Type 1C WinAnsi yes yes no 130 0 MIEPDP+TimesNewRomanPS-BoldMT Type 1C WinAnsi yes yes no 131 0 MIEPFA+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 132 0 MIEPFC+Times New Roman Bold,Bold Type 1C Custom yes yes yes 133 0 Times New Roman,Bold-Identity-H CID Type 0C Identity-H yes no no 134 0 Symbol-Identity-H CID Type 0C Identity-H yes no no 87 0 Times New Roman-Identity-H CID Type 0C Identity-H yes no no 94 0 MIFBNF+Calibri,Bold Type 1C Custom yes yes yes 97 0 MIFBNG+Calibri Type 1C Custom yes yes yes 101 0 MIFBOI+Calibri,BoldItalic Type 1C Custom yes yes yes 106 0 Calibri,Bold-Identity-H CID Type 0C Identity-H yes no no 107 0 MIFCHF+ArialMT Type 1C WinAnsi yes yes no 108 0 MIFDIA+Calibri,Italic Type 1C Custom yes yes yes 109 0 MIFDIB+Arial-BoldMT Type 1C WinAnsi yes yes no 110 0 Jhove (Rel. 1.6, 2011-01-04) Date: 2016-03-04 04:12:27 CET RepresentationInformation: genes_2012v3p521.pdf ReportingModule: PDF-hul, Rel. 1.8 (2009-05-22) LastModified: 2016-02-29 16:10:55 CET Size: 294099 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF, ISO PDF/A-1, Level B PDFMetadata: Objects: 161 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseThumbs Info: Title: Radiobiology and Reproduction What Can We Learn from Mammalian Females? Author: Aurora Ruiz-Herrera 1 Subject: Ionizing radiation damages DNA and induces mutations as well as chromosomal reorganizations. 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Ionizing radiation damages DNA and induces mutations as well as chromosomal reorganizations. Although radiotherapy increases survival among cancer patients, this treatment does not come without secondary effects, among which the most problematic is gonad meiosis oocytes fertility ionizing irradiation effects radiation-sensitivity DSBs genome instability Pages: Page: Label: 1 Page: Label: 2 Page: Label: 3 Page: Label: 4 Page: Label: 5 Page: Label: 6 Page: Label: 7 Page: Label: 8 Page: Label: 9 Page: Label: 10 Page: Label: 11 Page: Label: 12 Page: Label: 13 Page: Label: 14 Page: Label: 15 Page: Label: 16 Page: Label: 17 Page: Label: 18 Page: Label: 19 Page: Label: 20 Page: Label: 21 Page: Label: 22 Page: Label: 23 Page: Label: 24 Checksum: f609c7b5 Type: CRC32 Checksum: b787c9fe4055bea24184f24ec9eed186 Type: MD5 Checksum: c8022efdeaf5a8effaca07448d1d6408bad17842 Type: SHA-1