70c945a407c1579ef648231ba6eea769  pmc_23056462.pdf
e049b570bf247a0a2377eda322dc8f7e01bbba0d  pmc_23056462.pdf
878be177478033a83cc9937a52de2454841dcd4c258ff3c32cb9a44136c38104  pmc_23056462.pdf

Title:          deb_pone.0046810 1..7
Creator:        3B2 Total Publishing System 7.51n/W
Producer:       Acrobat Distiller 5.0 (Windows)
CreationDate:   Fri Sep 21 14:41:14 2012 CEST
ModDate:        Fri Sep 28 10:25:13 2012 CEST
Tagged:         no
UserProperties: no
Suspects:       no
Form:           none
JavaScript:     no
Pages:          7
Encrypted:      no
Page size:      612 x 791 pts
Page rot:       0
File size:      437281 bytes
Optimized:      yes
PDF version:    1.3


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
LLFBCJ+AdvP40319B                    Type 1C           WinAnsi          yes yes no      66  0
LLFBCK+AdvP41461E                    Type 1C           MacRoman         yes yes no      67  0
LLFBCL+AdvP403A40                    Type 1C           Custom           yes yes no      68  0
LLFBDL+AdvP7DA6                      Type 1C           Custom           yes yes yes     69  0
LLFBDM+AdvT377                       Type 1C           Custom           yes yes no      80  0
LLFBDN+AdvP49811                     Type 1C           WinAnsi          yes yes no      81  0
LLFBDO+AdvP697C                      Type 1C           Custom           yes yes yes     82  0
LLFBKO+AdvP40798                     Type 1C           Custom           yes yes yes     49  0
LLFBKP+AdvP4C4E74                    Type 1C           Custom           yes yes yes     54  0
LLFBLA+AdvP4C4E51                    Type 1C           Custom           yes yes yes     50  0
LLFBLB+AdvP4C4E46                    Type 1C           Custom           yes yes yes     52  0
LLFBMC+AdvP49812                     Type 1C           WinAnsi          yes yes no      53  0
LLFBKM+AdvP497E3                     Type 1C           WinAnsi          yes yes no      48  0
LLFBKN+AdvP497E2                     Type 1C           WinAnsi          yes yes no      47  0
LLFBND+AdvPi1                        Type 1C           WinAnsi          yes yes no      58  0
LLFBOD+AdvP4041BD                    Type 1C           WinAnsi          yes yes no      57  0
LLFBOE+AdvP3EAA99                    Type 1C           WinAnsi          yes yes no      56  0


Jhove (Rel. 1.28.0, 2023-05-18)
 Date: 2024-01-18 02:35:10 CET
 RepresentationInformation: pmc_23056462.pdf
  ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16)
  LastModified: 2018-01-26 08:11:20 CET
  Size: 437281
  Format: PDF
  Version: 1.3
  Status: Well-Formed and valid
  SignatureMatches:
   PDF-hul
  MIMEtype: application/pdf
  Profile: Linearized PDF
  PDFMetadata: 
   Objects: 107
   FreeObjects: 1
   IncrementalUpdates: 1
   DocumentCatalog: 
    PageLayout: SinglePage
    PageMode: UseNone
   Info: 
    Title: deb_pone.0046810 1..7
    Creator: 3B2 Total Publishing System 7.51n/W
    Producer: Acrobat Distiller 5.0 (Windows)
    CreationDate: Fri Sep 21 14:41:14 CEST 2012
    ModDate: Fri Sep 28 10:25:13 CEST 2012
   ID: 0xdaf255136c78b7c960622c5483eb24fa, 0xda0081d5ba42fe4180e779fe0333bbf9
   Filters: 
    FilterPipeline: FlateDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1376
      ImageHeight: 1046
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 981
      ImageHeight: 680
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
   Fonts: 
    Type1: 
     Font: 
      BaseFont: LLFBCJ+AdvP40319B
      FontSubset: true
      FirstChar: 44
      LastChar: 121
      FontDescriptor: 
       FontName: LLFBCJ+AdvP40319B
       Flags: Nonsymbolic
       FontBBox: -31, -239, 1197, 750
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: LLFBCK+AdvP41461E
      FontSubset: true
      FirstChar: 37
      LastChar: 247
      FontDescriptor: 
       FontName: LLFBCK+AdvP41461E
       Flags: Nonsymbolic
       FontBBox: -31, -239, 1354, 750
       FontFile3: true
      Encoding: MacRomanEncoding
     Font: 
      BaseFont: LLFBCL+AdvP403A40
      FontSubset: true
      FirstChar: 25
      LastChar: 180
      FontDescriptor: 
       FontName: LLFBCL+AdvP403A40
       Flags: Nonsymbolic
       FontBBox: -41, -239, 1125, 750
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
     Font: 
      BaseFont: LLFBDL+AdvP7DA6
      FontSubset: true
      FirstChar: 35
      LastChar: 50
      FontDescriptor: 
       FontName: LLFBDL+AdvP7DA6
       Flags: Serif, Symbolic
       FontBBox: -20, -208, 1000, 770
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: LLFBKN+AdvP497E2
      FontSubset: true
      FirstChar: 48
      LastChar: 57
      FontDescriptor: 
       FontName: LLFBKN+AdvP497E2
       Flags: Serif, Nonsymbolic
       FontBBox: -83, -239, 1000, 718
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: LLFBDM+AdvT377
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: LLFBDM+AdvT377
       Flags: Symbolic, Italic
       FontBBox: -187, -218, 1010, 979
       FontFile3: true
      EncodingDictionary: 
       Differences: true
     Font: 
      BaseFont: LLFBKM+AdvP497E3
      FontSubset: true
      FirstChar: 65
      LastChar: 121
      FontDescriptor: 
       FontName: LLFBKM+AdvP497E3
       Flags: Serif, Nonsymbolic
       FontBBox: -260, -239, 1093, 708
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: LLFBDN+AdvP49811
      FontSubset: true
      FirstChar: 37
      LastChar: 150
      FontDescriptor: 
       FontName: LLFBDN+AdvP49811
       Flags: Serif, Nonsymbolic
       FontBBox: -156, -250, 1000, 666
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: LLFBKO+AdvP40798
      FontSubset: true
      FirstChar: 124
      LastChar: 126
      FontDescriptor: 
       FontName: LLFBKO+AdvP40798
       Flags: Serif, Symbolic
       FontBBox: -20, -218, 1239, 718
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: LLFBDO+AdvP697C
      FontSubset: true
      FirstChar: 43
      LastChar: 109
      FontDescriptor: 
       FontName: LLFBDO+AdvP697C
       Flags: Serif, Symbolic
       FontBBox: -177, -291, 1083, 1010
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: LLFBLA+AdvP4C4E51
      FontSubset: true
      FirstChar: 61
      LastChar: 61
      FontDescriptor: 
       FontName: LLFBLA+AdvP4C4E51
       Flags: Symbolic
       FontBBox: -31, -239, 1041, 750
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: LLFBLB+AdvP4C4E46
      FontSubset: true
      FirstChar: 1
      LastChar: 112
      FontDescriptor: 
       FontName: LLFBLB+AdvP4C4E46
       Flags: Serif, Symbolic
       FontBBox: -15, -1160, 1020, 40
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: LLFBMC+AdvP49812
      FontSubset: true
      FirstChar: 68
      LastChar: 118
      FontDescriptor: 
       FontName: LLFBMC+AdvP49812
       Flags: Serif, Nonsymbolic
       FontBBox: -197, -250, 1083, 687
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: LLFBKP+AdvP4C4E74
      FontSubset: true
      FirstChar: 1
      LastChar: 189
      FontDescriptor: 
       FontName: LLFBKP+AdvP4C4E74
       Flags: Symbolic
       FontBBox: -20, -958, 1114, 770
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: LLFBOE+AdvP3EAA99
      FontSubset: true
      FirstChar: 120
      LastChar: 120
      FontDescriptor: 
       FontName: LLFBOE+AdvP3EAA99
       Flags: Serif, Nonsymbolic, Italic
       FontBBox: -156, -239, 1000, 739
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: LLFBOD+AdvP4041BD
      FontSubset: true
      FirstChar: 45
      LastChar: 121
      FontDescriptor: 
       FontName: LLFBOD+AdvP4041BD
       Flags: Nonsymbolic
       FontBBox: -104, -239, 1083, 750
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: LLFBND+AdvPi1
      FontSubset: true
      FirstChar: 54
      LastChar: 54
      FontDescriptor: 
       FontName: LLFBND+AdvPi1
       Flags: Serif, Nonsymbolic, Italic
       FontBBox: 13, -323, 958, 824
       FontFile3: true
      Encoding: WinAnsiEncoding
   XMP: <x:xmpmeta xmlns:x="adobe:ns:meta/" x:xmptk="Adobe XMP Core 4.2.1-c041 52.342996, 2008/05/07-20:48:00        ">
   <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
      <rdf:Description rdf:about=""
            xmlns:pdf="http://ns.adobe.com/pdf/1.3/">
         <pdf:Producer>Acrobat Distiller 5.0 (Windows)</pdf:Producer>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xmp="http://ns.adobe.com/xap/1.0/">
         <xmp:CreateDate>2012-09-21T13:41:14+01:00</xmp:CreateDate>
         <xmp:ModifyDate>2012-09-28T16:25:13+08:00</xmp:ModifyDate>
         <xmp:MetadataDate>2012-09-28T16:25:13+08:00</xmp:MetadataDate>
         <xmp:CreatorTool>3B2 Total Publishing System 7.51n/W</xmp:CreatorTool>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:dc="http://purl.org/dc/elements/1.1/">
         <dc:format>application/pdf</dc:format>
         <dc:title>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">deb_pone.0046810 1..7</rdf:li>
            </rdf:Alt>
         </dc:title>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xmpMM="http://ns.adobe.com/xap/1.0/mm/">
         <xmpMM:DocumentID>uuid:e0a782c1-d76c-4851-8ab9-d2551e590385</xmpMM:DocumentID>
         <xmpMM:InstanceID>uuid:ab1e8c0e-788f-4f51-bb89-e007e96be448</xmpMM:InstanceID>
      </rdf:Description>
   </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Sequence: 1
    Page: 
     Sequence: 2
    Page: 
     Sequence: 3
    Page: 
     Sequence: 4
    Page: 
     Sequence: 5
    Page: 
     Sequence: 6
    Page: 
     Sequence: 7
  Checksum: 79f6a5d7
   Type: CRC32
  Checksum: 70c945a407c1579ef648231ba6eea769
   Type: MD5
  Checksum: e049b570bf247a0a2377eda322dc8f7e01bbba0d
   Type: SHA-1
  Checksum: 878be177478033a83cc9937a52de2454841dcd4c258ff3c32cb9a44136c38104
   Type: SHA-256