689ed4b075cfdf34b1279d29e2b281c5 pmc_23181023.pdf 6ab2e3a3a14121ab482ba1332ed9b50a88a096ca pmc_23181023.pdf b42f4bf1b8ec8ca4a7bb04ac591d730b18b34cf0016a988ec0f68b7a40b0bb4d pmc_23181023.pdf Title: Protein aggregation profile of the human kinome Subject: Protein aggregation into amyloid fibrils is associated with the onset of an increasing number of human disorders, including Alzheimer's disease, diabetes, and some types of cancer. Keywords: protein kinases, protein aggregation, amyloid, protein evolution, AGGRESCAN Author: Salvador Ventura Creator: LaTeX with hyperref package Producer: Acrobat Distiller 8.0.0 (Windows) CreationDate: Sat Nov 10 14:30:09 2012 CET ModDate: Wed Aug 21 16:39:00 2013 CEST Tagged: yes UserProperties: no Suspects: no Form: none JavaScript: no Pages: 10 Encrypted: no Page size: 595.276 x 779.528 pts Page rot: 0 File size: 4464504 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- NGICBH+Univers-LightOblique Type 1C WinAnsi yes yes no 446 0 SNBPSY+Calibri-BoldItalic TrueType WinAnsi yes yes no 444 0 YWDZYM+Calibri-BoldItalic CID TrueType Identity-H yes yes yes 451 0 ENICPJ+Univers-BoldOblique Type 1C WinAnsi yes yes no 450 0 NGICBH+Univers-LightOblique Type 1C WinAnsi yes yes no 447 0 KCDBGA+Univers-Black Type 1C WinAnsi yes yes no 416 0 KCDBGB+Univers-Light Type 1C 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223 0 Jhove (Rel. 1.6, 2011-01-04) Date: 2018-06-05 04:58:46 CEST RepresentationInformation: pmc_23181023.pdf ReportingModule: PDF-hul, Rel. 1.8 (2009-05-22) LastModified: 2018-01-26 08:10:50 CET Size: 4464504 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Tagged PDF PDFMetadata: Objects: 525 FreeObjects: 1 IncrementalUpdates: 2 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: true CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: Protein aggregation profile of the human kinome Children: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@21588809 Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2aae9190 Children: Item: Title: Aggregation Properties of Kinomes Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2f333739 Item: Title: Aggregation Properties of the Human Kinome Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@77468bd9 Item: Title: Amyloidogenic Regions in Human Kinase Domains Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@12bb4df8 Item: Title: Aggregation and Amyloidogenic Properties of Human Kinase Groups Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4cc77c2e Item: Title: Aggregation Properties of Protein Kinase Groups in Different Species Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7a7b0070 Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@39a054a5 Item: Title: Materials and Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@71bc1ae4 Children: Item: Title: Dataset Curation Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6ed3ef1 Item: Title: AGGRESCAN Calculations Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2437c6dc Item: Title: Composition of Kinase Domains Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1f89ab83 Item: Title: Analysis of the Human Kinome Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e73f9ac Item: Title: Detection of Amyloidogenic Patterns Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@61064425 Item: Title: Intrinsical Unfolding Prediction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7b1d7fff Item: Title: Acknowledgments Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@299a06ac Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@383534aa Info: Title: Protein aggregation profile of the human kinome Author: Salvador Ventura Subject: Protein aggregation into amyloid fibrils is associated with the onset of an increasing number of human disorders, including Alzheimer's disease, diabetes, and some types of cancer. 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