314aa2e23cf82803531119bc2c8ad761  bmcstrbio_a2013m3v3n3.pdf
67c7070929c5c79c83437532804e4d71d858611b  bmcstrbio_a2013m3v3n3.pdf
a68282a3bd25b14decc59543c356e4131d4bf68862f5cd6b1a9fad0a4e4eb78d  bmcstrbio_a2013m3v3n3.pdf

Title:          The role of Cysteine 6.47 in class A GPCRs
Creator:        Arbortext Advanced Print Publisher 9.1.440/W Unicode
Producer:       Acrobat Distiller 10.0.0 (Windows)
CreationDate:   Thu Mar 28 00:11:46 2013
ModDate:        Thu Mar 28 00:12:27 2013
Tagged:         no
Pages:          11
Encrypted:      no
Page size:      595.276 x 793.701 pts
File size:      2551340 bytes
Optimized:      yes
PDF version:    1.3

name                                 type              emb sub uni object ID
------------------------------------ ----------------- --- --- --- ---------
PHCEDF+AdvTTe45e47d2                 Type 1C           yes yes no     383  0
PHCEEG+AdvTTb5929f4c                 Type 1C           yes yes no     384  0
PHCEEH+AdvTT1b53b5fb.I               Type 1C           yes yes no     385  0
PHCFAD+AdvTT7329fd89.I               Type 1C           yes yes no     386  0
PHCFAE+AdvTTaf7f9f4f.B               Type 1C           yes yes no     387  0
PHCFCE+AdvTT99c4c969                 Type 1C           yes yes no     218  0
PHCFCF+AdvTTb5929f4c+20              Type 1C           yes yes no     219  0
PHCFCG+AdvTT86d47313                 Type 1C           yes yes no     220  0
PHCFDH+AdvTT86d47313+20              Type 1C           yes yes no     221  0
PHCGDC+AdvTT8861b38f.I               Type 1C           yes yes no     222  0
PHCGDD+AdvTT86d47313+03              Type 1C           yes yes yes    223  0
PHCGEE+AdvTT99c4c969+22              Type 1C           yes yes yes     68  0
PHCGEF+AdvTT99c4c969+03              Type 1C           yes yes yes    224  0
PHCGEG+AdvTTb5929f4c+03              Type 1C           yes yes yes    225  0
PHCGFG+AdvTTe45e47d2+03              Type 1C           yes yes yes    226  0
PHCGHH+AdvTT8861b38f.I+03            Type 1C           yes yes yes     92  0
PHCGIH+AdvTT83913201.I               Type 1C           yes yes no     227  0
PHENIJ+AdvTT99c4c969+20              Type 1C           yes yes no     179  0
PHENMI+AdvP4C4E74                    Type 1C           yes yes no     187  0
PHENOI+AdvP4C4E59                    Type 1C           yes yes no     188  0
PHEOKF+FrutigerLTStd-Bold            Type 1C           yes yes yes    201  0
PHEOOE+FrutigerLTStd-Roman           Type 1C           yes yes yes    202  0

Jhove (Rel. 1.4, 2009-07-30)
 Date: 2013-10-18 22:46:10 GMT+01:00
 RepresentationInformation: bmcstrbio_a2013m3v3n3.pdf
  ReportingModule: PDF-hul, Rel. 1.8 (2009-05-22)
  LastModified: 2013-10-18 09:56:03 GMT+01:00
  Size: 2551340
  Format: PDF
  Version: 1.3
  Status: Well-Formed, but not valid
  SignatureMatches:
   PDF-hul
  ErrorMessage: Invalid destination object
   Offset: 2535374
  ErrorMessage: Invalid destination object
   Offset: 2535374
  MIMEtype: application/pdf
  Profile: Linearized PDF
  PDFMetadata: 
   Objects: 404
   FreeObjects: 1
   IncrementalUpdates: 1
   DocumentCatalog: 
    PageLayout: SinglePage
    PageMode: UseNone
    Outlines: 
     Item: 
      Title: Abstract
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@19c247a0
      Children: 
       Item: 
        Title: Background
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@21ec6696
       Item: 
        Title: Results
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@27431340
       Item: 
        Title: Conclusions
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@24a4e2e3
     Item: 
      Title: Background
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@452bb7e0
     Item: 
      Title: Results and discussion
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@3934f69a
      Children: 
       Item: 
        Title: Residue prevalence and side chain conformation of position 6.47
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@442a15cd
       Item: 
        Title: MD simulations of A/C/T/SxxP model peptides
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@26fd68b1
       Item: 
        Title: TM6/TM7 interactions involving 6.47
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@46e45076
       Item: 
        Title: 6.47 modulates D2.50-N7.49 interaction
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@375e9756
     Item: 
      Title: Methods
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2321ab80
     Item: 
      Title: Conclusions
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@77827284
     Item: 
      Title: Methods
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@152c7568
      Children: 
       Item: 
        Title: Molecular dynamics simulations of model peptides
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@19d009b4
       Item: 
        Title: Analysis of sequence positions
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@292d15a9
     Item: 
      Title: Additional file
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4ee91f5d
     Item: 
      Title: Competing interests
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2b0a3b24
     Item: 
      Title: Authors’ contributions
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2cb0ce8f
     Item: 
      Title: Acknowledgements
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@bc92535
     Item: 
      Title: Author details
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42a9c09e
     Item: 
      Title: References
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@16a4e743
   Info: 
    Title: The role of Cysteine 6.47 in class A GPCRs
    Creator: Arbortext Advanced Print Publisher 9.1.440/W Unicode
    Producer: Acrobat Distiller 10.0.0 (Windows)
    CreationDate: Wed Mar 27 17:11:46 GMT+01:00 2013
    ModDate: Wed Mar 27 17:12:27 GMT+01:00 2013
   ID: 0xe4fbde26649aac53d4713ced5a52e8f9, 0xdc36523b8d5bdaac020b8bec39d09208
   Filters: 
    FilterPipeline: FlateDecode
    FilterPipeline: DCTDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      MIMEType: application/pdf
      CompressionScheme: JPEG
      ColorSpace: RGB
      ImageWidth: 2007
      ImageLength: 949
      BitsPerSample: 8
    Image: 
     NisoImageMetadata: 
      MIMEType: application/pdf
      ColorSpace: RGB
      ImageWidth: 896
      ImageLength: 2585
      BitsPerSample: 8
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      MIMEType: application/pdf
      ColorSpace: RGB
      ImageWidth: 1420
      ImageLength: 1001
      BitsPerSample: 8
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      MIMEType: application/pdf
      CompressionScheme: JPEG
      ColorSpace: RGB
      ImageWidth: 1420
      ImageLength: 1477
      BitsPerSample: 8
   Fonts: 
    Type1: 
     Font: 
      BaseFont: PHCGIH+AdvTT83913201.I
      FontSubset: true
      FirstChar: 43
      LastChar: 117
      FontDescriptor: 
       FontName: PHCGIH+AdvTT83913201.I
       Flags: Nonsymbolic
       FontBBox: -93, -250, 906, 875
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: PHCGDC+AdvTT8861b38f.I
      FontSubset: true
      FirstChar: 43
      LastChar: 119
      FontDescriptor: 
       FontName: PHCGDC+AdvTT8861b38f.I
       Flags: Nonsymbolic
       FontBBox: -187, -239, 1062, 875
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: PHCGEE+AdvTT99c4c969+22
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: PHCGEE+AdvTT99c4c969+22
       Flags: Symbolic
       FontBBox: -10, -229, 1020, 906
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: PHCEDF+AdvTTe45e47d2
      FontSubset: true
      FirstChar: 40
      LastChar: 183
      FontDescriptor: 
       FontName: PHCEDF+AdvTTe45e47d2
       Flags: Nonsymbolic
       FontBBox: -218, -250, 833, 875
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: PHCFCE+AdvTT99c4c969
      FontSubset: true
      FirstChar: 37
      LastChar: 197
      FontDescriptor: 
       FontName: PHCFCE+AdvTT99c4c969
       Flags: Nonsymbolic
       FontBBox: -41, -250, 854, 885
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: PHCFAD+AdvTT7329fd89.I
      FontSubset: true
      FirstChar: 46
      LastChar: 121
      FontDescriptor: 
       FontName: PHCFAD+AdvTT7329fd89.I
       Flags: Nonsymbolic
       FontBBox: -218, -250, 885, 864
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: PHCGFG+AdvTTe45e47d2+03
      FontSubset: true
      FirstChar: 1
      LastChar: 3
      FontDescriptor: 
       FontName: PHCGFG+AdvTTe45e47d2+03
       Flags: Symbolic
       FontBBox: -531, -250, 791, 947
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: PHCGDD+AdvTT86d47313+03
      FontSubset: true
      FirstChar: 1
      LastChar: 7
      FontDescriptor: 
       FontName: PHCGDD+AdvTT86d47313+03
       Flags: Symbolic
       FontBBox: -135, -250, 906, 822
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: PHCFAE+AdvTTaf7f9f4f.B
      FontSubset: true
      FirstChar: 45
      LastChar: 122
      FontDescriptor: 
       FontName: PHCFAE+AdvTTaf7f9f4f.B
       Flags: Nonsymbolic
       FontBBox: -218, -250, 875, 895
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: PHENMI+AdvP4C4E74
      FontSubset: true
      FirstChar: 48
      LastChar: 48
      FontDescriptor: 
       FontName: PHENMI+AdvP4C4E74
       Flags: Nonsymbolic
       FontBBox: -20, -958, 1114, 770
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: PHCFCF+AdvTTb5929f4c+20
      FontSubset: true
      FirstChar: 146
      LastChar: 150
      FontDescriptor: 
       FontName: PHCFCF+AdvTTb5929f4c+20
       Flags: Nonsymbolic
       FontBBox: -218, -208, 1375, 864
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: PHCGEG+AdvTTb5929f4c+03
      FontSubset: true
      FirstChar: 1
      LastChar: 7
      FontDescriptor: 
       FontName: PHCGEG+AdvTTb5929f4c+03
       Flags: Symbolic
       FontBBox: -531, -260, 802, 968
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: PHENOI+AdvP4C4E59
      FontSubset: true
      FirstChar: 46
      LastChar: 46
      FontDescriptor: 
       FontName: PHENOI+AdvP4C4E59
       Flags: Nonsymbolic
       FontBBox: -31, -250, 1000, 750
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: PHCGHH+AdvTT8861b38f.I+03
      FontSubset: true
      FirstChar: 1
      LastChar: 3
      FontDescriptor: 
       FontName: PHCGHH+AdvTT8861b38f.I+03
       Flags: Symbolic
       FontBBox: -114, -239, 937, 822
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: PHCGEF+AdvTT99c4c969+03
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: PHCGEF+AdvTT99c4c969+03
       Flags: Symbolic
       FontBBox: -531, -250, 791, 958
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: PHEOKF+FrutigerLTStd-Bold
      FontSubset: true
      FirstChar: 32
      LastChar: 147
      FontDescriptor: 
       FontName: PHEOKF+FrutigerLTStd-Bold
       Flags: Symbolic, ForceBold
       FontBBox: -166, -250, 1000, 935
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: PHCFCG+AdvTT86d47313
      FontSubset: true
      FirstChar: 37
      LastChar: 197
      FontDescriptor: 
       FontName: PHCFCG+AdvTT86d47313
       Flags: Serif, Nonsymbolic
       FontBBox: -218, -239, 1020, 875
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: PHCFDH+AdvTT86d47313+20
      FontSubset: true
      FirstChar: 146
      LastChar: 148
      FontDescriptor: 
       FontName: PHCFDH+AdvTT86d47313+20
       Flags: Nonsymbolic
       FontBBox: -218, -218, 1291, 812
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: PHENIJ+AdvTT99c4c969+20
      FontSubset: true
      FirstChar: 146
      LastChar: 146
      FontDescriptor: 
       FontName: PHENIJ+AdvTT99c4c969+20
       Flags: Nonsymbolic
       FontBBox: -218, -197, 1583, 864
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: PHCEEH+AdvTT1b53b5fb.I
      FontSubset: true
      FirstChar: 43
      LastChar: 122
      FontDescriptor: 
       FontName: PHCEEH+AdvTT1b53b5fb.I
       Flags: Nonsymbolic
       FontBBox: -114, -250, 864, 854
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: PHCEEG+AdvTTb5929f4c
      FontSubset: true
      FirstChar: 40
      LastChar: 242
      FontDescriptor: 
       FontName: PHCEEG+AdvTTb5929f4c
       Flags: Nonsymbolic
       FontBBox: -41, -250, 812, 864
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: PHEOOE+FrutigerLTStd-Roman
      FontSubset: true
      FirstChar: 32
      LastChar: 121
      FontDescriptor: 
       FontName: PHEOOE+FrutigerLTStd-Roman
       Flags: Symbolic
       FontBBox: -169, -250, 1000, 935
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
   XMP: <x:xmpmeta xmlns:x="adobe:ns:meta/"
           x:xmptk="Adobe XMP Core 4.2.1-c043 52.372728, 2009/01/18-15:08:04">
   <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
      <rdf:Description xmlns:xmp="http://ns.adobe.com/xap/1.0/" rdf:about="">
         <xmp:Label>BMC Structural Biology 2013, 13:1. doi:10.1186/1472-6807-13-3</xmp:Label>
      </rdf:Description>
      <rdf:Description xmlns:dc="http://purl.org/dc/elements/1.1/" rdf:about="">
         <dc:format>application/pdf</dc:format>
         <dc:identifier>http://dx.doi.org/10.1186/1472-6807-13-3</dc:identifier>
         <dc:creator>
            <rdf:Seq>
               <rdf:li>Mireia Olivella</rdf:li>
               <rdf:li>Gianluigi Caltabiano</rdf:li>
               <rdf:li>Arnau Cordom�</rdf:li>
            </rdf:Seq>
         </dc:creator>
         <dc:title>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">The role of Cysteine 6.47 in class A GPCRs</rdf:li>
            </rdf:Alt>
         </dc:title>
         <dc:description>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">BMC Structural Biology 2013, 13:1. doi:10.1186/1472-6807-13-3</rdf:li>
            </rdf:Alt>
         </dc:description>
         <dc:publisher>
            <rdf:Bag>
               <rdf:li>BMC Structural Biology</rdf:li>
            </rdf:Bag>
         </dc:publisher>
         <dc:date>
            <rdf:Seq>
               <rdf:li>2013-03-15</rdf:li>
            </rdf:Seq>
         </dc:date>
         <dc:rights>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">� 2013 Olivella et al.; licensee BioMed Central Ltd.</rdf:li>
            </rdf:Alt>
         </dc:rights>
      </rdf:Description>
      <rdf:Description xmlns:xmpRights="http://ns.adobe.com/xap/1.0/rights/" rdf:about="">
         <xmpRights:Marked>True</xmpRights:Marked>
      </rdf:Description>
      <rdf:Description xmlns:prism="http://prismstandard.org/namespaces/basic/2.0/" rdf:about="">
         <prism:url>BMC Structural Biology</prism:url>
         <prism:doi>10.1186/1472-6807-13-3</prism:doi>
         <prism:pageRange>1</prism:pageRange>
         <prism:startingPage>1</prism:startingPage>
         <prism:endingPage>1</prism:endingPage>
         <prism:copyright>� 2013 Olivella et al.; licensee BioMed Central Ltd.</prism:copyright>
         <prism:publicationName>BMC Structural Biology</prism:publicationName>
         <prism:aggregationType>journal</prism:aggregationType>
         <prism:volume>13</prism:volume>
         <prism:rightsAgent>reprints@biomedcentral.com</prism:rightsAgent>
         <prism:publicationDate>2013-03-15</prism:publicationDate>
         <prism:number>1</prism:number>
         <prism:issueidentifier>1</prism:issueidentifier>
         <prism:issn>BMC Structural Biology</prism:issn>
      </rdf:Description>
   </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Label: 0
     Thumb: true
    Page: 
     Label: 1
     Sequence: 2
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 280, 401, 285, 411
       Destination: 164
      Annotation: 
       Subtype: Link
       Rect: 101, 353, 105, 363
       Destination: 164
      Annotation: 
       Subtype: Link
       Rect: 113, 281, 118, 291
       Destination: 164
      Annotation: 
       Subtype: Link
       Rect: 280, 281, 285, 291
       Destination: 164
      Annotation: 
       Subtype: Link
       Rect: 83, 245, 88, 255
       Destination: 164
      Annotation: 
       Subtype: Link
       Rect: 160, 221, 165, 231
       Destination: 164
      Annotation: 
       Subtype: Link
       Rect: 182, 173, 187, 183
       Destination: 164
      Annotation: 
       Subtype: Link
       Rect: 189, 173, 193, 183
       Destination: 164
      Annotation: 
       Subtype: Link
       Rect: 187, 161, 192, 171
       Destination: 164
      Annotation: 
       Subtype: Link
       Rect: 194, 161, 203, 171
       Destination: 164
      Annotation: 
       Subtype: Link
       Rect: 425, 425, 434, 435
       Destination: 164
      Annotation: 
       Subtype: Link
       Rect: 438, 425, 447, 435
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 348, 377, 353, 387
       Destination: 28
      Annotation: 
       Subtype: Link
       Rect: 370, 245, 380, 255
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 326, 161, 335, 171
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 343, 137, 352, 147
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 355, 137, 365, 147
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 114, 128, 184, 135
      Annotation: 
       Subtype: Link
       Rect: 264, 67, 379, 74
     Thumb: true
    Page: 
     Label: 2
     Sequence: 3
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 126, 346, 157, 356
       Destination: 147
      Annotation: 
       Subtype: Link
       Rect: 59, 310, 69, 320
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 137, 274, 147, 284
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 149, 274, 158, 284
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 229, 202, 238, 212
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 77, 166, 86, 176
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 88, 166, 98, 176
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 231, 154, 241, 164
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 275, 130, 285, 140
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 182, 94, 187, 104
       Destination: 28
      Annotation: 
       Subtype: Link
       Rect: 248, 58, 258, 68
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 260, 58, 269, 68
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 404, 310, 413, 320
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 384, 298, 393, 308
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 378, 262, 387, 272
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 389, 262, 399, 272
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 257, 655, 264, 663
       Destination: 164
      Annotation: 
       Subtype: Link
       Rect: 256, 641, 264, 649
       Destination: 164
      Annotation: 
       Subtype: Link
       Rect: 255, 627, 263, 635
       Destination: 164
      Annotation: 
       Subtype: Link
       Rect: 255, 613, 263, 621
       Destination: 164
      Annotation: 
       Subtype: Link
       Rect: 255, 599, 263, 607
       Destination: 164
      Annotation: 
       Subtype: Link
       Rect: 256, 585, 263, 593
       Destination: 164
      Annotation: 
       Subtype: Link
       Rect: 253, 571, 261, 579
       Destination: 164
      Annotation: 
       Subtype: Link
       Rect: 257, 557, 265, 565
       Destination: 164
      Annotation: 
       Subtype: Link
       Rect: 257, 543, 264, 551
       Destination: 164
      Annotation: 
       Subtype: Link
       Rect: 256, 529, 264, 537
       Destination: 164
      Annotation: 
       Subtype: Link
       Rect: 254, 515, 262, 523
       Destination: 164
      Annotation: 
       Subtype: Link
       Rect: 256, 501, 264, 509
       Destination: 164
      Annotation: 
       Subtype: Link
       Rect: 256, 487, 263, 495
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 259, 473, 267, 481
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 259, 459, 267, 467
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 256, 445, 264, 453
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 259, 431, 267, 439
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 257, 417, 265, 425
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 256, 403, 263, 411
       Destination: 182
     Thumb: true
    Page: 
     Label: 3
     Sequence: 4
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 198, 694, 229, 704
       Destination: 147
      Annotation: 
       Subtype: Link
       Rect: 174, 646, 179, 656
       Destination: 73
      Annotation: 
       Subtype: Link
       Rect: 248, 490, 258, 500
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 260, 490, 269, 500
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 147, 406, 157, 415
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 159, 406, 169, 415
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 171, 406, 181, 415
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 183, 370, 216, 379
       Destination: 147
      Annotation: 
       Subtype: Link
       Rect: 157, 346, 161, 355
       Destination: 164
      Annotation: 
       Subtype: Link
       Rect: 307, 670, 317, 680
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 356, 670, 361, 680
       Destination: 97
      Annotation: 
       Subtype: Link
       Rect: 483, 634, 515, 644
       Destination: 147
      Annotation: 
       Subtype: Link
       Rect: 525, 406, 535, 416
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 351, 394, 356, 404
       Destination: 97
     Thumb: true
    Page: 
     Label: 4
     Sequence: 5
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 388, 442, 398, 452
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 400, 442, 410, 452
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 412, 442, 421, 452
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 458, 442, 462, 452
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 507, 310, 516, 320
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 438, 250, 447, 260
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 451, 250, 460, 260
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 374, 226, 384, 236
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 375, 178, 385, 188
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 396, 59, 403, 66
       Destination: 182
     Thumb: true
    Page: 
     Label: 5
     Sequence: 6
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 226, 287, 230, 296
       Destination: 28
      Annotation: 
       Subtype: Link
       Rect: 226, 263, 231, 272
       Destination: 28
      Annotation: 
       Subtype: Link
       Rect: 252, 203, 283, 212
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 59, 191, 69, 200
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 285, 155, 290, 164
       Destination: 28
      Annotation: 
       Subtype: Link
       Rect: 198, 119, 229, 128
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 209, 83, 219, 92
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 222, 83, 232, 92
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 140, 59, 150, 68
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 494, 335, 503, 344
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 505, 335, 515, 344
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 342, 323, 347, 332
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 334, 131, 343, 140
       Destination: 164
      Annotation: 
       Subtype: Link
       Rect: 345, 131, 355, 140
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 381, 59, 390, 68
       Destination: 164
     Thumb: true
    Page: 
     Label: 6
     Sequence: 7
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 258, 646, 263, 656
       Destination: 73
      Annotation: 
       Subtype: Link
       Rect: 132, 550, 137, 560
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 273, 514, 278, 524
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 396, 646, 401, 656
       Destination: 114
     Thumb: true
    Page: 
     Label: 7
     Sequence: 8
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 193, 694, 198, 704
       Destination: 136
      Annotation: 
       Subtype: Link
       Rect: 181, 526, 186, 536
       Destination: 136
      Annotation: 
       Subtype: Link
       Rect: 213, 346, 222, 356
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 226, 346, 235, 356
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 185, 322, 194, 332
       Destination: 164
      Annotation: 
       Subtype: Link
       Rect: 104, 298, 114, 308
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 213, 166, 217, 176
       Destination: 73
      Annotation: 
       Subtype: Link
       Rect: 501, 202, 511, 212
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 391, 130, 401, 140
       Destination: 182
      Annotation: 
       Subtype: Link
       Rect: 370, 106, 380, 116
       Destination: 193
      Annotation: 
       Subtype: Link
       Rect: 511, 94, 521, 104
       Destination: 193
      Annotation: 
       Subtype: Link
       Rect: 391, 82, 401, 92
       Destination: 193
     Thumb: true
    Page: 
     Label: 8
     Sequence: 9
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 150, 658, 160, 668
       Destination: 193
      Annotation: 
       Subtype: Link
       Rect: 206, 634, 216, 644
       Destination: 193
      Annotation: 
       Subtype: Link
       Rect: 275, 622, 285, 632
       Destination: 193
      Annotation: 
       Subtype: Link
       Rect: 277, 514, 287, 524
       Destination: 193
      Annotation: 
       Subtype: Link
       Rect: 217, 382, 290, 392
      Annotation: 
       Subtype: Link
       Rect: 56, 370, 77, 380
      Annotation: 
       Subtype: Link
       Rect: 61, 309, 153, 316
     Thumb: true
    Page: 
     Label: 9
     Sequence: 10
     Thumb: true
    Page: 
     Label: 10
     Sequence: 11
     Thumb: true
  Checksum: f6bd194a
   Type: CRC32
  Checksum: 314aa2e23cf82803531119bc2c8ad761
   Type: MD5
  Checksum: 67c7070929c5c79c83437532804e4d71d858611b
   Type: SHA-1