3e398cffaf52cdb09f1101edfbcb380b pmc_24381570.pdf 048fbe7aa70e80bd53995dc232c5a2bd1d37d49a pmc_24381570.pdf e649ddb53e630dd8555eb164d2640ae7e8146d4feabb77dffa17fa6582b3270b pmc_24381570.pdf Title: The repertoires of peptides presented by MHC-II in the thymus and in peripheral tissue: a clue for autoimmunity? Subject: T-cell tolerance to self-antigens is established in the thymus through the recognition by developing thymocytes of self-peptide-MHC complexes and induced and maintained in the periphery. Keywords: peptide repertoire, MHC-II, human, thymus, peripheral tissues Author: Dolores Jaraquemada Creator: LaTeX with hyperref package Producer: pdfTeX-1.40.13 CreationDate: Mon Dec 16 08:12:02 2013 CET ModDate: Mon Dec 16 12:15:56 2013 CET Tagged: yes UserProperties: no Suspects: no Form: none JavaScript: no Pages: 7 Encrypted: no Page size: 595.276 x 779.528 pts Page rot: 0 File size: 955371 bytes Optimized: yes PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- QQASBH+NimbusRomNo9L-Regu Type 1 Custom yes yes no 390 0 WLCLXU+Univers-Black Type 1 Custom yes yes no 391 0 EOUUPU+Univers-Light Type 1 Custom yes yes no 392 0 MRWOGC+Univers Type 1 Custom yes yes no 393 0 QVFZJM+Univers-BoldOblique Type 1 Custom yes yes no 394 0 LMNXYS+Univers-LightOblique Type 1 Custom yes yes no 395 0 YDEDIJ+Univers-Bold Type 1 Custom yes yes no 396 0 BZQJES+Univers-CondensedBold Type 1 Custom yes yes no 397 0 FREKQW+Minion-Regular Type 1 Custom yes yes no 398 0 XGISTJ+Minion-Italic Type 1 Custom yes yes no 399 0 XXEAZQ+MTSYN Type 1 Builtin yes yes no 209 0 ENDALY+Minion-Bold Type 1 Custom yes yes no 213 0 ITOYRU+MTGU Type 1 Builtin yes yes no 217 0 DUDFCK+Minion-BoldItalic Type 1 Custom yes yes no 218 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2022-01-29 02:42:23 CET RepresentationInformation: pmc_24381570.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2018-01-29 05:55:13 CET Size: 955371 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF, Tagged PDF PDFMetadata: Objects: 487 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: The repertoires of peptides presented by MHC-II in the thymus and in peripheral tissue: a clue for autoimmunity? Children: Item: Title: Peptide repertoire in thymus Item: Title: MHC-II peptide repertoire in autoimmunity Item: Title: Mechanisms generating repertoire differences Children: Item: Title: Proteolysis Item: Title: Differential dose of antigen in peripheral tissue vs. thymus Item: Title: Post-translational modifications in the tissue Item: Title: Expression of HLA-DR and DM in autoimmunity affected tissue Item: Title: Unique T-cell recognition of tissue-derived antigens Item: Title: Concluding remarks Item: Title: References Info: Title: The repertoires of peptides presented by MHC-II in the thymus and in peripheral tissue: a clue for autoimmunity? Author: Dolores Jaraquemada Subject: T-cell tolerance to self-antigens is established in the thymus through the recognition by developing thymocytes of self-peptide-MHC complexes and induced and maintained in the periphery. 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