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Profile: Linearized PDF PDFMetadata: Objects: 188 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Abstract Destination: sectionAbs1 Children: Item: Title: Background Destination: sectionASec1 Item: Title: Methods Destination: sectionASec2 Item: Title: Results Destination: sectionASec3 Item: Title: Conclusions Destination: sectionASec4 Item: Title: Background Destination: sectionSec1 Item: Title: Methods Destination: sectionSec2 Item: Title: Results and discussion Destination: sectionSec3 Item: Title: Conclusion Destination: sectionSec4 Item: Title: Competing interests Destination: ArtNote1 Item: Title: Authors’ contributions Destination: ArtNote2 Item: Title: Acknowledgements Destination: sectionArt1316492318918201 Item: Title: Author details Destination: sectionaunote1 Item: Title: References Destination: sectionBib1 Info: Title: Adverse events during the titration phase of interferon-beta in remitting-relapsing multiple sclerosis are not predicted by body mass index nor by pharmacodynamic biomarkers Creator: Arbortext Advanced Print Publisher 9.1.440/W Unicode Producer: Acrobat Distiller 10.1.5 (Windows) CreationDate: Fri Jul 12 23:54:54 CEST 2013 ModDate: Fri Jul 12 23:55:34 CEST 2013 ID: 0x44630f68e1d5a55a4fc67bf9298b06d0, 0x3c1c42111a20b3f245bcdc24a3a6c45e Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: DFIKMM+AdvTT86d47313+03 FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: DFIKMM+AdvTT86d47313+03 Flags: Symbolic FontBBox: -135, -250, 906, 822 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: DFILJK+AdvTT7329fd89.I FontSubset: true FirstChar: 46 LastChar: 121 FontDescriptor: FontName: DFILJK+AdvTT7329fd89.I Flags: Nonsymbolic FontBBox: -218, -250, 885, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DFIKMN+AdvTT86d47313+20 FontSubset: true FirstChar: 146 LastChar: 150 FontDescriptor: FontName: 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DFIKLK+AdvTT99c4c969 FontSubset: true FirstChar: 40 LastChar: 121 FontDescriptor: FontName: DFIKLK+AdvTT99c4c969 Flags: Nonsymbolic FontBBox: -41, -250, 854, 885 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DFIKLL+AdvTTb5929f4c+03 FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: DFIKLL+AdvTTb5929f4c+03 Flags: Symbolic FontBBox: -531, -260, 802, 968 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: DFIKML+AdvTT86d47313 FontSubset: true FirstChar: 37 LastChar: 239 FontDescriptor: FontName: DFIKML+AdvTT86d47313 Flags: Serif, Nonsymbolic FontBBox: -218, -239, 1020, 875 FontFile3: true Encoding: WinAnsiEncoding XMP: BMC Neurology 2013, 13:1. doi:10.1186/1471-2377-13-82 application/pdf http://dx.doi.org/10.1186/1471-2377-13-82 Delicias Mu�oz Antonio Escart�n Dolores Dapena Francisco Coret Dionisio Fern�ndez-Ur�a Domingo P�rez Bonaventura Casanova Cristina Guijarro-Castro Elvira Munteis Mar�a del-Campo Amigo Robustiano Pego Carmen Calles C�sar Garc�a-Rey Nuria Monsalve David S�nchez-Matienzo Adverse events during the titration phase of interferon-beta in remitting-relapsing multiple sclerosis are not predicted by body mass index nor by pharmacodynamic biomarkers BMC Neurology 2013, 13:1. doi:10.1186/1471-2377-13-82 BMC Neurology 2013-07-11 � 2013 Mu�oz et al.; licensee BioMed Central Ltd. Interferon �-1a Body mass index Biomarkers �2-microglobulin OAS Neopterin Adverse events True BMC Neurology 10.1186/1471-2377-13-82 1 1 1 � 2013 Mu�oz et al.; licensee BioMed Central Ltd. 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