4b64c97ff6f548742d09894ab6e5ccb9 303830.pdf be019756a75b5f9c49325f5e8e735e9e05c2ceba 303830.pdf 702c6c07fa5c80ca75d35dd5bf6b5af76a1789f704dbdd07f54a4e8f1e4d092d 303830.pdf Title: Trough colistin plasma level is an independent risk factor for nephrotoxicity: a prospective observational cohort study Creator: Arbortext Advanced Print Publisher 9.1.440/W Unicode Producer: Acrobat Distiller 10.1.5 (Windows) CreationDate: Tue Aug 27 12:49:27 2013 CEST ModDate: Tue Aug 27 12:49:49 2013 CEST Custom Metadata: no Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 9 Encrypted: no Page size: 595.276 x 793.701 pts Page rot: 0 File size: 215597 bytes Optimized: yes PDF version: 1.3 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- LAMCNN+AdvTTaf7f9f4f.B Type 1C WinAnsi yes yes no 282 0 LAMCNO+AdvTTe45e47d2 Type 1C WinAnsi yes yes no 283 0 LAMCNP+AdvTTb5929f4c Type 1C WinAnsi yes yes no 284 0 LAMCOA+AdvTT99c4c969 Type 1C WinAnsi yes yes no 285 0 LAMCPB+AdvTT5843c571+22 Type 1C Custom yes yes yes 272 0 LAMCPC+AdvTT86d47313 Type 1C WinAnsi yes yes no 286 0 LAMDLO+AdvTT7329fd89.I Type 1C WinAnsi yes yes no 287 0 LAMDOO+AdvTT86d47313+20 Type 1C WinAnsi yes yes no 136 0 LAMDOP+AdvTT86d47313+22 Type 1C Custom yes yes yes 137 0 LAMEAP+AdvTT86d47313+03 Type 1C Custom yes yes yes 27 0 LAMECA+AdvTT8861b38f.I Type 1C WinAnsi yes yes no 138 0 LAMEFA+AdvTTb5929f4c+20 Type 1C WinAnsi yes yes no 139 0 LAMEFB+AdvTT1b53b5fb.I Type 1C WinAnsi yes yes no 140 0 LAMEHB+AdvTT83913201.I Type 1C WinAnsi yes yes no 51 0 LAMEKB+AdvTTb5929f4c+22 Type 1C Custom yes yes yes 76 0 LAMEMB+AdvTT99c4c969+22 Type 1C Custom yes yes yes 95 0 LAMEPB+AdvTT99c4c969+20 Type 1C WinAnsi yes yes no 108 0 LAMFLN+FrutigerLTStd-Bold Type 1C Custom yes yes yes 119 0 LAMFON+FrutigerLTStd-Roman Type 1C Custom yes yes yes 120 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-12-05 03:06:13 CET RepresentationInformation: 303830.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2024-12-04 10:09:38 CET Size: 215597 Format: PDF Version: 1.3 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 304 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Abstract Destination: sectionAbs1 Children: Item: Title: Background Destination: sectionASec1 Item: Title: Methods Destination: sectionASec2 Item: Title: Results Destination: sectionASec3 Item: Title: Conclusions Destination: sectionASec4 Item: Title: Background Destination: sectionSec1 Item: Title: Methods Destination: sectionSec2 Children: Item: Title: Statistical analysis Destination: sectionSec3 Item: Title: Results Destination: sectionSec4 Item: Title: Discussion Destination: sectionSec5 Item: Title: Conclusions Destination: sectionSec6 Item: Title: Abbreviations Destination: sectionabr1 Item: Title: Competing interests Destination: ArtNote1 Item: Title: Authors’ contributions Destination: ArtNote2 Item: Title: Author details Destination: sectionaunote1 Item: Title: References Destination: sectionBib1 Info: Title: Trough colistin plasma level is an independent risk factor for nephrotoxicity: a prospective observational cohort study Creator: Arbortext Advanced Print Publisher 9.1.440/W Unicode Producer: Acrobat Distiller 10.1.5 (Windows) CreationDate: Tue Aug 27 12:49:27 CEST 2013 ModDate: Tue Aug 27 12:49:49 CEST 2013 ID: 0x1c7aca2a148e59d9fc5109d7f4d55ebb, 0x8679b74978fd4739346c0594d31526f9 Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: LAMDOO+AdvTT86d47313+20 FontSubset: true FirstChar: 146 LastChar: 150 FontDescriptor: FontName: LAMDOO+AdvTT86d47313+20 Flags: Nonsymbolic FontBBox: -218, -218, 1291, 812 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: LAMDOP+AdvTT86d47313+22 FontSubset: true FirstChar: 1 LastChar: 138 FontDescriptor: FontName: LAMDOP+AdvTT86d47313+22 Flags: Symbolic FontBBox: -166, -270, 1031, 906 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: LAMECA+AdvTT8861b38f.I FontSubset: true FirstChar: 80 LastChar: 118 FontDescriptor: FontName: LAMECA+AdvTT8861b38f.I Flags: Nonsymbolic FontBBox: -187, -239, 1062, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: LAMEFA+AdvTTb5929f4c+20 FontSubset: true FirstChar: 150 LastChar: 150 FontDescriptor: FontName: LAMEFA+AdvTTb5929f4c+20 Flags: Nonsymbolic FontBBox: -218, -208, 1375, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: LAMEFB+AdvTT1b53b5fb.I FontSubset: true FirstChar: 45 LastChar: 121 FontDescriptor: FontName: LAMEFB+AdvTT1b53b5fb.I Flags: Nonsymbolic FontBBox: -114, -250, 864, 854 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: LAMEKB+AdvTTb5929f4c+22 FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: LAMEKB+AdvTTb5929f4c+22 Flags: Symbolic FontBBox: -10, -218, 1083, 906 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: LAMEPB+AdvTT99c4c969+20 FontSubset: true FirstChar: 146 LastChar: 146 FontDescriptor: FontName: LAMEPB+AdvTT99c4c969+20 Flags: Nonsymbolic FontBBox: -218, -197, 1583, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: LAMCPB+AdvTT5843c571+22 FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: LAMCPB+AdvTT5843c571+22 Flags: Symbolic FontBBox: -156, -208, 802, 906 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: LAMEHB+AdvTT83913201.I FontSubset: true FirstChar: 80 LastChar: 80 FontDescriptor: FontName: LAMEHB+AdvTT83913201.I Flags: Nonsymbolic FontBBox: -93, -250, 906, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: LAMFLN+FrutigerLTStd-Bold FontSubset: true FirstChar: 32 LastChar: 147 FontDescriptor: FontName: LAMFLN+FrutigerLTStd-Bold Flags: Symbolic, ForceBold FontBBox: -166, -250, 1000, 935 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: LAMFON+FrutigerLTStd-Roman FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: LAMFON+FrutigerLTStd-Roman Flags: Symbolic FontBBox: -169, -250, 1000, 935 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: LAMCNN+AdvTTaf7f9f4f.B FontSubset: true FirstChar: 45 LastChar: 121 FontDescriptor: FontName: LAMCNN+AdvTTaf7f9f4f.B Flags: Nonsymbolic FontBBox: -218, -250, 875, 895 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: LAMCNO+AdvTTe45e47d2 FontSubset: true FirstChar: 37 LastChar: 237 FontDescriptor: FontName: LAMCNO+AdvTTe45e47d2 Flags: Nonsymbolic FontBBox: -218, -250, 833, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: LAMEAP+AdvTT86d47313+03 FontSubset: true FirstChar: 1 LastChar: 4 FontDescriptor: FontName: LAMEAP+AdvTT86d47313+03 Flags: Symbolic FontBBox: -135, -250, 906, 822 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: LAMCNP+AdvTTb5929f4c FontSubset: true FirstChar: 37 LastChar: 250 FontDescriptor: FontName: LAMCNP+AdvTTb5929f4c Flags: Nonsymbolic FontBBox: -41, -250, 812, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: LAMCOA+AdvTT99c4c969 FontSubset: true FirstChar: 37 LastChar: 176 FontDescriptor: FontName: LAMCOA+AdvTT99c4c969 Flags: Nonsymbolic FontBBox: -41, -250, 854, 885 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: LAMCPC+AdvTT86d47313 FontSubset: true FirstChar: 37 LastChar: 243 FontDescriptor: FontName: LAMCPC+AdvTT86d47313 Flags: Serif, Nonsymbolic FontBBox: -218, -239, 1020, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: LAMDLO+AdvTT7329fd89.I FontSubset: true FirstChar: 46 LastChar: 117 FontDescriptor: FontName: LAMDLO+AdvTT7329fd89.I Flags: Nonsymbolic FontBBox: -218, -250, 885, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: LAMEMB+AdvTT99c4c969+22 FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: LAMEMB+AdvTT99c4c969+22 Flags: Symbolic FontBBox: -10, -229, 1020, 906 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true XMP: BMC Infectious Diseases 2013, 13:1. doi:10.1186/1471-2334-13-380 application/pdf http://dx.doi.org/10.1186/1471-2334-13-380 Luisa Sorl� Sonia Luque Santiago Grau N�ria Berenguer Concepci�n Segura Mar�a Milagro Montero Francisco �lvarez-Lerma Hernando Knobel Natividad Benito Juan P Horcajada Trough colistin plasma level is an independent risk factor for nephrotoxicity: a prospective observational cohort study BMC Infectious Diseases 2013, 13:1. doi:10.1186/1471-2334-13-380 BMC Infectious Diseases 2013-08-19 � 2013 Sorl� et al.; licensee BioMed Central Ltd. Colistin Nephrotoxicity risk factors RIFLE criteria Colistin plasma levels True BMC Infectious Diseases 10.1186/1471-2334-13-380 1 1 1 � 2013 Sorl� et al.; licensee BioMed Central Ltd. BMC Infectious Diseases journal 13 reprints@biomedcentral.com 2013-08-19 1 1 BMC Infectious Diseases Colistin; Nephrotoxicity risk factors; RIFLE criteria; Colistin plasma levels Pages: Page: Label: 0 Annotations: Annotation: Subtype: Link Rect: 477, 231, 482, 241 Destination: 100 Annotation: Subtype: Link Rect: 485, 231, 490, 241 Destination: 100 Annotation: Subtype: Link Rect: 470, 171, 475, 181 Destination: 100 Annotation: Subtype: Link Rect: 412, 147, 417, 157 Destination: 100 Annotation: Subtype: Link Rect: 419, 147, 424, 157 Destination: 100 Annotation: Subtype: Link Rect: 114, 119, 192, 126 Annotation: Subtype: Link Rect: 264, 67, 379, 74 Thumb: true Page: Label: 1 Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 280, 694, 285, 704 Destination: 100 Annotation: Subtype: Link Rect: 179, 682, 184, 692 Destination: 100 Annotation: Subtype: Link Rect: 187, 682, 197, 692 Destination: 100 Annotation: Subtype: Link Rect: 226, 646, 231, 656 Destination: 100 Annotation: Subtype: Link Rect: 233, 646, 243, 656 Destination: 100 Annotation: Subtype: Link Rect: 431, 670, 441, 680 Destination: 100 Annotation: Subtype: Link Rect: 525, 562, 535, 572 Destination: 100 Annotation: Subtype: Link Rect: 334, 550, 338, 560 Destination: 1 Annotation: Subtype: Link Rect: 428, 346, 438, 356 Destination: 100 Annotation: Subtype: Link Rect: 403, 310, 413, 320 Destination: 111 Thumb: true Page: Label: 2 Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 81, 682, 91, 692 Destination: 111 Annotation: Subtype: Link Rect: 254, 502, 264, 512 Destination: 111 Annotation: Subtype: Link Rect: 404, 538, 414, 548 Destination: 111 Annotation: Subtype: Link Rect: 443, 190, 448, 200 Destination: 32 Annotation: Subtype: Link Rect: 504, 130, 509, 140 Destination: 39 Annotation: Subtype: Link Rect: 330, 70, 335, 80 Destination: 39 Thumb: true Page: Label: 3 Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 495, 394, 500, 404 Destination: 54 Annotation: Subtype: Link Rect: 507, 106, 512, 116 Destination: 80 Thumb: true Page: Label: 4 Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 208, 262, 213, 272 Destination: 80 Annotation: Subtype: Link Rect: 475, 154, 480, 164 Destination: 100 Annotation: Subtype: Link Rect: 482, 154, 487, 164 Destination: 100 Annotation: Subtype: Link Rect: 489, 154, 499, 164 Destination: 111 Annotation: Subtype: Link Rect: 501, 154, 511, 164 Destination: 111 Annotation: Subtype: Link Rect: 398, 82, 403, 92 Destination: 100 Annotation: Subtype: Link Rect: 405, 82, 410, 92 Destination: 100 Thumb: true Page: Label: 5 Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 122, 286, 132, 296 Destination: 100 Annotation: Subtype: Link Rect: 134, 286, 144, 296 Destination: 111 Annotation: Subtype: Link Rect: 150, 262, 160, 272 Destination: 111 Annotation: Subtype: Link Rect: 162, 262, 172, 272 Destination: 111 Annotation: Subtype: Link Rect: 210, 226, 215, 236 Destination: 100 Annotation: Subtype: Link Rect: 217, 226, 227, 236 Destination: 111 Annotation: Subtype: Link Rect: 231, 226, 241, 236 Destination: 111 Annotation: Subtype: Link Rect: 222, 154, 232, 164 Destination: 111 Annotation: Subtype: Link Rect: 240, 130, 250, 140 Destination: 111 Annotation: Subtype: Link Rect: 308, 226, 313, 236 Destination: 100 Annotation: Subtype: Link Rect: 315, 226, 320, 236 Destination: 100 Annotation: Subtype: Link Rect: 322, 226, 332, 236 Destination: 100 Annotation: Subtype: Link Rect: 334, 226, 344, 236 Destination: 111 Annotation: Subtype: Link Rect: 347, 226, 357, 236 Destination: 111 Annotation: Subtype: Link Rect: 513, 142, 523, 152 Destination: 111 Annotation: Subtype: Link Rect: 525, 142, 535, 152 Destination: 111 Annotation: Subtype: Link Rect: 481, 130, 486, 140 Destination: 100 Thumb: true Page: Label: 6 Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 227, 286, 237, 296 Destination: 111 Annotation: Subtype: Link Rect: 201, 190, 205, 200 Destination: 100 Annotation: Subtype: Link Rect: 372, 682, 382, 692 Destination: 111 Annotation: Subtype: Link Rect: 483, 526, 493, 536 Destination: 111 Annotation: Subtype: Link Rect: 391, 394, 401, 404 Destination: 111 Annotation: Subtype: Link Rect: 365, 370, 370, 380 Destination: 100 Annotation: Subtype: Link Rect: 397, 274, 402, 284 Destination: 100 Annotation: Subtype: Link Rect: 404, 274, 414, 284 Destination: 111 Annotation: Subtype: Link Rect: 331, 190, 341, 200 Destination: 111 Annotation: Subtype: Link Rect: 343, 190, 353, 200 Destination: 111 Thumb: true Page: Label: 7 Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 59, 646, 69, 656 Destination: 111 Annotation: Subtype: Link Rect: 185, 382, 195, 392 Destination: 111 Annotation: Subtype: Link Rect: 197, 382, 206, 392 Destination: 111 Thumb: true Page: Label: 8 Sequence: 9 Thumb: true Checksum: d931740d Type: CRC32 Checksum: 4b64c97ff6f548742d09894ab6e5ccb9 Type: MD5 Checksum: be019756a75b5f9c49325f5e8e735e9e05c2ceba Type: SHA-1 Checksum: 702c6c07fa5c80ca75d35dd5bf6b5af76a1789f704dbdd07f54a4e8f1e4d092d Type: SHA-256