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Title:           Oxidative stress and mitochondrial dysfunction in Kindler syndrome
Subject:          2014, :. doi:10.1186/s13023-014-0211-8
Keywords:        Kindlin1,Oxidative stress,Mitochondria,Keratinocytes,Genodermatosis
Author:          Elisabeth Zapatero-Solana
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       Item: 
        Title: Methods
        Destination: sectionASec2
       Item: 
        Title: Results
        Destination: sectionASec3
       Item: 
        Title: Conclusions
        Destination: sectionASec4
     Item: 
      Title: Background
      Destination: sectionSec1
     Item: 
      Title: Methods
      Destination: sectionSec2
      Children: 
       Item: 
        Title: Skin biopsies
        Destination: sectionSec3
       Item: 
        Title: Electron microscopy
        Destination: sectionSec4
        Children: 
         Item: 
          Title: Mutational analysis
          Destination: sectionSec5
       Item: 
        Title: Primary keratinocyte culture
        Destination: sectionSec6
       Item: 
        Title: Measurement of lipid peroxides
        Destination: sectionSec7
       Item: 
        Title: Measurement of GSSG/GSH ratio
        Destination: sectionSec8
       Item: 
        Title: qPCR
        Destination: sectionSec9
       Item: 
        Title: Redox biosensors experiments
        Destination: sectionSec10
       Item: 
        Title: Western blotting
        Destination: sectionSec11
       Item: 
        Title: Confocal microscopy
        Destination: sectionSec12
       Item: 
        Title: Statistical analysis
        Destination: sectionSec13
     Item: 
      Title: Results
      Destination: sectionSec14
      Children: 
       Item: 
        Title: FERMT1 mutations correlate with reduced or absent kindlin-1 protein in KS keratinocytes
        Destination: sectionSec15
       Item: 
        Title: Keratinocytes from KS patients are prone to oxidative stress
        Destination: sectionSec16
       Item: 
        Title: Mitochondrial structure, localization and function is altered in KS epidermis and keratinocytes in culture
        Destination: sectionSec17
     Item: 
      Title: Discussion
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     Item: 
      Title: Conclusions
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     Item: 
      Title: Additional files
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     Item: 
      Title: Abbreviations
      Destination: sectionabr1
     Item: 
      Title: Competing interests
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     Item: 
      Title: Authors’ contributions
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     Item: 
      Title: Acknowledgements
      Destination: sections13023-014-0211-8
     Item: 
      Title: Author details
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      Title: References
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