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IFFHOK+WpwfhqFrutigerLTStd-Roman Type 1C Custom yes yes yes 301 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-11-14 03:03:54 CET RepresentationInformation: 302479.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2024-11-13 16:06:42 CET Size: 1031493 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 597 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: EN Outlines: Item: Title: Abstract Destination: sectionAbs1 Children: Item: Title: Background Destination: sectionASec1 Item: Title: Results Destination: sectionASec2 Item: Title: Conclusions Destination: sectionASec3 Item: Title: Background Destination: sectionSec1 Item: Title: Results and discussion Destination: sectionSec2 Children: Item: Title: Rapid isolation of postsynaptic fractions from small PM samples Destination: sectionSec3 Item: Title: A simple screening method to measure PM synapse proteome integrity Destination: sectionSec4 Item: Title: Synaptic proteome integrity varies between cortical and other brain regions Destination: sectionSec5 Item: Title: Isolation and proteomics of human MAGUK associated signalling complexes Destination: sectionSec6 Item: Title: Human MASC proteins in disease Destination: sectionSec7 Item: Title: Conclusions Destination: sectionSec8 Item: Title: Methods Destination: sectionSec9 Children: Item: Title: Human neocortex samples Destination: sectionSec10 Item: Title: Rapid isolation of postsynaptic fractions from PM tissue Destination: sectionSec11 Item: Title: Isolation of postsynaptic densities from human post-mortem brain samples Destination: sectionSec12 Item: Title: Isolation of human MAGUK Associated Signalling Complexes (MASC) Destination: sectionSec13 Item: Title: Sample preparation for quantitative MS Destination: sectionSec14 Item: Title: Analysis of MASC genes causing genetic nervous system diseases Destination: sectionSec15 Item: Title: Text-mining and expert curation of MASC gene mutation associations to human nervous system disorders Destination: sectionSec16 Item: Title: Additional files Destination: sectionSec17 Item: Title: Abbreviations Destination: sectionabr1 Item: Title: Competing interests Destination: ArtNote1 Item: Title: Authors’ contributions Destination: ArtNote2 Item: Title: Acknowledgements Destination: sections13041-014-0088-4 Item: Title: Author details Destination: sectionaunote1 Item: Title: References Destination: sectionBib1 Info: Title: Author: Subject: Keywords: Synapse,Proteomics,Mass spectrometry,Supercomplex,Post-mortem brain,MAGUK,Psychiatric disorder Creator: Arbortext Advanced Print Publisher 9.1.440/W Unicode Producer: Acrobat Distiller 11.0.9(Windows) CreationDate: Mon Dec 15 05:48:38 CET 2014 ModDate: Fri Sep 18 02:11:37 CEST 2015 ID: 0xdac79d7be2d220f92c62c414dcfbd981, 0x760e08b1a8a2914abbee169b74db8796 Filters: FilterPipeline: 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