533acd74f822b1c52bc4c38afffb2a75 pmc_24688469.pdf 51ab632df2065305954bbf841ac6f1b304ad0e91 pmc_24688469.pdf c5e2eb85d1f548b8400abdd640099bfe9998dbd6291e1f8113eb57146411e287 pmc_24688469.pdf Title: Epigenetic alterations in hippocampus of SAMP8 senescent mice and modulation by voluntary physical exercise Subject: The senescence-accelerated SAMP8 mouse model displays features of cognitive decline and Alzheimer's disease. Keywords: exercise, aging, Alzheimer, SAMP8, microRNAs Author: Perla Kaliman Creator: LaTeX with hyperref package Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Sat Mar 15 07:04:04 2014 CET ModDate: Sat Mar 15 09:03:30 2014 CET Tagged: yes UserProperties: no Suspects: no Form: none JavaScript: no Pages: 10 Encrypted: no Page size: 595.276 x 779.528 pts Page rot: 0 File size: 1105569 bytes Optimized: no PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- LODDHJ+Univers-Black Type 1C WinAnsi yes yes no 419 0 BGJFCM+Univers-Light Type 1C Custom yes yes no 420 0 BGJFGN+Univers Type 1C WinAnsi yes yes no 424 0 BGJFGO+Univers-BoldOblique Type 1C WinAnsi yes yes no 425 0 BGJFGP+Univers-LightOblique Type 1C Custom yes yes no 426 0 BGJFHP+Univers-Bold Type 1C MacRoman yes yes no 432 0 BGJFIA+Univers-CondensedBold Type 1C WinAnsi yes yes no 433 0 BGJFCK+Minion-Regular Type 1C MacRoman yes yes no 434 0 LODDHJ+Univers-Black Type 1C Custom yes yes yes 456 0 BGJFKC+MTGU Type 1C Custom yes yes yes 197 0 BGJFKA+MTSYN Type 1C Custom yes yes yes 204 0 BGJFKB+Minion-Italic Type 1C WinAnsi yes yes no 203 0 BGJFLD+RMTMI Type 1C WinAnsi yes yes no 209 0 BGJFLE+Minion-Bold Type 1C Custom yes yes no 207 0 BGPLAM+RMTMIB Type 1C WinAnsi yes yes no 215 0 BHDPOJ+MSAM5 Type 1C Custom yes yes no 217 0 BHJMCN+Minion-BoldItalic Type 1C WinAnsi yes yes no 218 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2020-11-11 06:19:19 CET RepresentationInformation: pmc_24688469.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2020-08-10 03:55:15 CEST Size: 1105569 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Tagged PDF PDFMetadata: Objects: 547 FreeObjects: 1 IncrementalUpdates: 3 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: true CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: Epigenetic alterations in hippocampus of SAMP8 senescent mice and modulation by voluntary physical exercise Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Children: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Item: Title: Materials and Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Children: Item: Title: Animal Care and Voluntary Exercise Paradigm Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Item: Title: Plasma Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: Total RNA Extraction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Item: Title: Real-Time Quantitative PCR Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Item: Title: Western Blots Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Item: Title: microRNA Expression Array Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Item: Title: Statistical Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b Children: Item: Title: Positive Effects of 8 Weeks of Voluntary Wheel Running in Hippocampal Gene Expression and IGF1 Plasma Levels Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6950e31 Item: Title: microRNA Expression Profile is Altered in SAMP8 Hippocampus and Modulated by Physical Exercise Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@b7dd107 Item: Title: Animal Care and Voluntary Exercise Paradigm Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42eca56e Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@52f759d7 Item: Title: Acknowledgments Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7cbd213e Item: Title: Supplementary Material Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@192d3247 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@3ecd23d9 Info: Title: Epigenetic alterations in hippocampus of SAMP8 senescent mice and modulation by voluntary physical exercise Author: Perla Kaliman Subject: The senescence-accelerated SAMP8 mouse model displays features of cognitive decline and Alzheimer's disease. 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