c69cba1ee9b7f2859f2bf78f1272fa4a  pmc_24781918.pdf
db92f845aecb1485f5c0f1a16724adf6737518c2  pmc_24781918.pdf
c93de9d6020df5f8b76c55f26b355bb2df7bd6d1e32803d872ba6f900504bc90  pmc_24781918.pdf

Title:          pone.0095744 1..14
Creator:        3B2 Total Publishing System 7.51n/W
Producer:       Acrobat Distiller 9.0.0 (Windows); modified using iText 5.0.3 (c) 1T3XT BVBA
CreationDate:   Tue Apr 22 04:51:57 2014 CEST
ModDate:        Fri Apr 25 07:32:22 2014 CEST
Tagged:         no
UserProperties: no
Suspects:       no
Form:           none
JavaScript:     no
Pages:          14
Encrypted:      no
Page size:      612.283 x 790.866 pts
Page rot:       0
File size:      2149260 bytes
Optimized:      no
PDF version:    1.5

name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
DADOMM+AdvP40319B                    Type 1C           WinAnsi          yes yes no     134  0
DADOMN+AdvP41461E                    Type 1C           WinAnsi          yes yes no      13  0
DADOMO+AdvP403A40                    Type 1C           Custom           yes yes no      15  0
DADONO+AdvT377                       Type 1C           Custom           yes yes no     135  0
DADOOP+AdvP49811                     Type 1C           Custom           yes yes no      17  0
DADOPA+AdvP49812                     Type 1C           WinAnsi          yes yes no      18  0
PLNJBE+AdvP403A40                    Type 1C           Custom           yes yes no     680  0
DAEBEG+AdvP43B38B                    Type 1C           WinAnsi          yes yes no      14  0
DAEBEH+AdvP4C4E74                    Type 1C           Custom           yes yes yes     16  0
DAEBFJ+AdvP4068C                     Type 1C           WinAnsi          yes yes no      19  0
DAEBEF+AdvP40798                     Type 1C           Custom           yes yes yes     20  0
DAEBFH+AdvPi2                        Type 1C           WinAnsi          yes yes no      21  0
DAEBEE+AdvP497E2                     Type 1C           WinAnsi          yes yes no      22  0
DAEBFI+AdvP4980C                     Type 1C           Custom           yes yes yes     23  0
DAEBED+AdvP497E3                     Type 1C           WinAnsi          yes yes no      24  0
DAEFFC+AdvP4C4E46                    Type 1C           Custom           yes yes yes     29  0
DAEFFD+AdvP4C4E51                    Type 1C           Custom           yes yes yes     30  0
DAELKN+AdvP4041BD                    Type 1C           WinAnsi          yes yes no      31  0
DAEOLL+AdvP4C4E59                    Type 1C           Custom           yes yes yes     42  0
DAFJGL+AdvP4980F                     Type 1C           WinAnsi          yes yes no      53  0
DAGBJJ+AdvPi1                        Type 1C           WinAnsi          yes yes no      61  0
DAGBNJ+AdvP413831                    Type 1C           WinAnsi          yes yes no      67  0
DAGCEH+AdvP497E4                     Type 1C           WinAnsi          yes yes no      72  0
NXZOGC+CMR10                         Type 1            Builtin          yes yes no     532  0

Jhove (Rel. 1.22.1, 2019-04-17)
 Date: 2020-11-11 06:18:21 CET
 RepresentationInformation: pmc_24781918.pdf
  ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17)
  LastModified: 2018-01-29 05:50:28 CET
  Size: 2149260
  Format: PDF
  Version: 1.5
  Status: Well-Formed and valid
  SignatureMatches:
   PDF-hul
  MIMEtype: application/pdf
  Profile: ISO PDF/A-1, Level B
  PDFMetadata: 
   Objects: 809
   FreeObjects: 3
   IncrementalUpdates: 10
   DocumentCatalog: 
    PageLayout: SinglePage
    PageMode: UseNone
   Info: 
    Title: pone.0095744 1..14
    Creator: 3B2 Total Publishing System 7.51n/W
    Producer: Acrobat Distiller 9.0.0 (Windows); modified using iText 5.0.3 (c) 1T3XT BVBA
    CreationDate: Tue Apr 22 04:51:57 CEST 2014
    ModDate: Fri Apr 25 08:02:22 CEST 2014
   ID: 0xea92b138fb673dea21a47b8df2a2b13b, 0x21a3a187eb980545b78de5efabce0a9f
   Filters: 
    FilterPipeline: FlateDecode
    FilterPipeline: DCTDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 104
      ImageHeight: 103
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     ColorSpace: ICCBased
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 834
      ImageHeight: 846
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1594
      ImageHeight: 928
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 972
      ImageHeight: 896
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1345
      ImageHeight: 1265
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 993
      ImageHeight: 489
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1407
      ImageHeight: 790
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 640
      ImageHeight: 1445
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
   Fonts: 
    Type1: 
     Font: 
      BaseFont: DAGBNJ+AdvP413831
      FontSubset: true
      FirstChar: 48
      LastChar: 67
      FontDescriptor: 
       FontName: DAGBNJ+AdvP413831
       Flags: Nonsymbolic
       FontBBox: -427, -250, 1020, 760
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DADOMM+AdvP40319B
      FontSubset: true
      FirstChar: 67
      LastChar: 119
      FontDescriptor: 
       FontName: DADOMM+AdvP40319B
       Flags: Nonsymbolic
       FontBBox: -31, -239, 1197, 750
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DADONO+AdvT377
      FontSubset: true
      FirstChar: 2
      LastChar: 2
      FontDescriptor: 
       FontName: DADONO+AdvT377
       Flags: Symbolic
       FontBBox: -187, -218, 1010, 979
       FontFile3: true
      EncodingDictionary: 
       Differences: true
     Font: 
      BaseFont: PLNJBE+AdvP403A40
      FontSubset: true
      FirstChar: 25
      LastChar: 180
      FontDescriptor: 
       FontName: PLNJBE+AdvP403A40
       Flags: Nonsymbolic
       FontBBox: -41, -239, 1125, 750
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
     Font: 
      BaseFont: DAGCEH+AdvP497E4
      FontSubset: true
      FirstChar: 48
      LastChar: 52
      FontDescriptor: 
       FontName: DAGCEH+AdvP497E4
       Flags: Serif, Nonsymbolic
       FontBBox: -187, -239, 1062, 718
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DAEOLL+AdvP4C4E59
      FontSubset: true
      FirstChar: 37
      LastChar: 37
      FontDescriptor: 
       FontName: DAEOLL+AdvP4C4E59
       Flags: Serif, Symbolic
       FontBBox: -31, -250, 1000, 750
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: DADOMN+AdvP41461E
      FontSubset: true
      FirstChar: 44
      LastChar: 152
      FontDescriptor: 
       FontName: DADOMN+AdvP41461E
       Flags: Nonsymbolic
       FontBBox: -31, -239, 1354, 750
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DAEBEG+AdvP43B38B
      FontSubset: true
      FirstChar: 86
      LastChar: 118
      FontDescriptor: 
       FontName: DAEBEG+AdvP43B38B
       Flags: Serif, Nonsymbolic
       FontBBox: -260, -239, 1041, 739
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DADOMO+AdvP403A40
      FontSubset: true
      FirstChar: 25
      LastChar: 180
      FontDescriptor: 
       FontName: DADOMO+AdvP403A40
       Flags: Nonsymbolic
       FontBBox: -41, -239, 1125, 750
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
     Font: 
      BaseFont: DAEBEH+AdvP4C4E74
      FontSubset: true
      FirstChar: 2
      LastChar: 240
      FontDescriptor: 
       FontName: DAEBEH+AdvP4C4E74
       Flags: Symbolic
       FontBBox: -20, -958, 1114, 770
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: DADOOP+AdvP49811
      FontSubset: true
      FirstChar: 25
      LastChar: 216
      FontDescriptor: 
       FontName: DADOOP+AdvP49811
       Flags: Serif, Nonsymbolic
       FontBBox: -156, -250, 1000, 666
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
     Font: 
      BaseFont: DADOPA+AdvP49812
      FontSubset: true
      FirstChar: 46
      LastChar: 118
      FontDescriptor: 
       FontName: DADOPA+AdvP49812
       Flags: Serif, Nonsymbolic
       FontBBox: -197, -250, 1083, 687
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DAEBFJ+AdvP4068C
      FontSubset: true
      FirstChar: 76
      LastChar: 84
      FontDescriptor: 
       FontName: DAEBFJ+AdvP4068C
       Flags: Serif, Nonsymbolic
       FontBBox: -208, -322, 958, 895
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DAEBEF+AdvP40798
      FontSubset: true
      FirstChar: 122
      LastChar: 126
      FontDescriptor: 
       FontName: DAEBEF+AdvP40798
       Flags: Serif, Symbolic
       FontBBox: -20, -218, 1239, 718
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: NXZOGC+CMR10
      FontSubset: true
      FirstChar: 10
      LastChar: 127
      FontDescriptor: 
       FontName: NXZOGC+CMR10
       Flags: Symbolic
       FontBBox: -40, -250, 1009, 750
       FontFile: true
     Font: 
      BaseFont: DAEBFH+AdvPi2
      FontSubset: true
      FirstChar: 63
      LastChar: 91
      FontDescriptor: 
       FontName: DAEBFH+AdvPi2
       Flags: Serif, Nonsymbolic
       FontBBox: 16, -335, 981, 833
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DAFJGL+AdvP4980F
      FontSubset: true
      FirstChar: 40
      LastChar: 150
      FontDescriptor: 
       FontName: DAFJGL+AdvP4980F
       Flags: Serif, Nonsymbolic
       FontBBox: -145, -250, 1145, 708
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DAEBEE+AdvP497E2
      FontSubset: true
      FirstChar: 40
      LastChar: 116
      FontDescriptor: 
       FontName: DAEBEE+AdvP497E2
       Flags: Serif, Nonsymbolic
       FontBBox: -83, -239, 1000, 718
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DAEBFI+AdvP4980C
      FontSubset: true
      FirstChar: 118
      LastChar: 119
      FontDescriptor: 
       FontName: DAEBFI+AdvP4980C
       Flags: Serif, Symbolic
       FontBBox: -72, -343, 1187, 1031
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: DAEBED+AdvP497E3
      FontSubset: true
      FirstChar: 65
      LastChar: 120
      FontDescriptor: 
       FontName: DAEBED+AdvP497E3
       Flags: Serif, Nonsymbolic
       FontBBox: -260, -239, 1093, 708
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DAEFFC+AdvP4C4E46
      FontSubset: true
      FirstChar: 2
      LastChar: 105
      FontDescriptor: 
       FontName: DAEFFC+AdvP4C4E46
       Flags: Serif, Symbolic
       FontBBox: 13, -2359, 1387, 40
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: DAGBJJ+AdvPi1
      FontSubset: true
      FirstChar: 58
      LastChar: 58
      FontDescriptor: 
       FontName: DAGBJJ+AdvPi1
       Flags: Serif, Nonsymbolic
       FontBBox: 13, -323, 958, 824
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DAEFFD+AdvP4C4E51
      FontSubset: true
      FirstChar: 58
      LastChar: 61
      FontDescriptor: 
       FontName: DAEFFD+AdvP4C4E51
       Flags: Symbolic
       FontBBox: -31, -239, 1041, 750
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: DAELKN+AdvP4041BD
      FontSubset: true
      FirstChar: 101
      LastChar: 118
      FontDescriptor: 
       FontName: DAELKN+AdvP4041BD
       Flags: Nonsymbolic
       FontBBox: -104, -239, 1083, 750
       FontFile3: true
      Encoding: WinAnsiEncoding
   XMP: <x:xmpmeta xmlns:x='adobe:ns:meta/' x:xmptk='Image::ExifTool 8.15'>
<rdf:RDF xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>

 <rdf:Description rdf:about=''
  xmlns:crossmark='http://crossref.org/crossmark/1.0/'>
  <crossmark:CrossMarkDomains>www.plosone.org</crossmark:CrossMarkDomains>
  <crossmark:CrossmarkDomainExclusive>false</crossmark:CrossmarkDomainExclusive>
  <crossmark:DOI>10.1371/journal.pone.0095744</crossmark:DOI>
  <crossmark:MajorVersionDate>2014-04-29</crossmark:MajorVersionDate>
 </rdf:Description>

 <rdf:Description rdf:about=''
  xmlns:dc='http://purl.org/dc/elements/1.1/'>
  <dc:format>application/pdf</dc:format>
  <dc:identifier>doi:10.1371/journal.pone.0095744</dc:identifier>
  <dc:title>
   <rdf:Alt>
    <rdf:li xml:lang='x-default'>pone.0095744 1..14</rdf:li>
   </rdf:Alt>
  </dc:title>
 </rdf:Description>

 <rdf:Description rdf:about=''
  xmlns:pdf='http://ns.adobe.com/pdf/1.3/'>
  <pdf:Producer>Acrobat Distiller 9.0.0 (Windows); modified using iText 5.0.3 (c) 1T3XT BVBA</pdf:Producer>
 </rdf:Description>

 <rdf:Description rdf:about=''
  xmlns:prism='http://prismstandard.org/namespaces/basic/2.1/'>
  <prism:url>
   <rdf:Bag>
    <rdf:li>http://dx.doi.org/10.1371/journal.pone.0095744</rdf:li>
   </rdf:Bag>
  </prism:url>
 </rdf:Description>

 <rdf:Description rdf:about=''
  xmlns:xap='http://ns.adobe.com/xap/1.0/'>
  <xap:CreateDate>2014-04-22T10:51:57+08:00</xap:CreateDate>
  <xap:CreatorTool>3B2 Total Publishing System 7.51n/W</xap:CreatorTool>
  <xap:MetadataDate>2014-04-25T11:02:22+05:30</xap:MetadataDate>
  <xap:ModifyDate>2014-04-25T11:02:22+05:30</xap:ModifyDate>
 </rdf:Description>

 <rdf:Description rdf:about=''
  xmlns:xapMM='http://ns.adobe.com/xap/1.0/mm/'>
  <xapMM:DocumentID>uuid:3cf6a33b-a06c-4bc2-bfef-13da18859f8b</xapMM:DocumentID>
  <xapMM:InstanceID>uuid:85974784-4e4e-4407-a9f1-8f7f731702b5</xapMM:InstanceID>
 </rdf:Description>
</rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Sequence: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 401, 374, 517, 381
      Annotation: 
       Subtype: Link
       Rect: 68, 345, 155, 352
       Destination: External
      Annotation: 
       Subtype: Link
       Rect: 325, 345, 434, 352
       Destination: External
      Annotation: 
       Subtype: Link
       Rect: 156, 329, 229, 336
       Destination: External
      Annotation: 
       Subtype: Link
       Rect: 492, 329, 538, 336
       Destination: External
      Annotation: 
       Subtype: Link
       Rect: 66, 321, 80, 328
       Destination: External
      Annotation: 
       Subtype: Link
       Rect: 352, 321, 412, 328
       Destination: External
      Annotation: 
       Subtype: Link
       Rect: 565, 732, 602, 695
    Page: 
     Sequence: 2
    Page: 
     Sequence: 3
    Page: 
     Sequence: 4
    Page: 
     Sequence: 5
    Page: 
     Sequence: 6
    Page: 
     Sequence: 7
    Page: 
     Sequence: 8
    Page: 
     Sequence: 9
    Page: 
     Sequence: 10
    Page: 
     Sequence: 11
    Page: 
     Sequence: 12
    Page: 
     Sequence: 13
    Page: 
     Sequence: 14
  Checksum: 3b59a71c
   Type: CRC32
  Checksum: c69cba1ee9b7f2859f2bf78f1272fa4a
   Type: MD5
  Checksum: db92f845aecb1485f5c0f1a16724adf6737518c2
   Type: SHA-1