55a4f7d566e54f8827ef07e3c54a0132 pmc_25170515.pdf 01de849d8e65cf5c36d8b4d2ccc4389428336810 pmc_25170515.pdf 13a53425834da88e373464a75d1c7c40042069589d6703ad938ac00a6da29feb pmc_25170515.pdf Title: Subject: BioMed Research International Keywords: Author: Creator: LaTeX with hyperref package Producer: Acrobat Distiller 7.0 (Windows); modified using iTextSharp™ 5.4.0 ©2000-2012 1T3XT BVBA (AGPL-version) CreationDate: Thu Aug 7 10:37:09 2014 CEST ModDate: Sun Aug 24 13:39:17 2014 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 8 Encrypted: no Page size: 600.05 x 792 pts Page rot: 0 File size: 547695 bytes Optimized: no PDF version: 1.3 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- MinionPro-It Type 1C Custom yes no yes 14 0 Minion-Black Type 1C WinAnsi yes no no 15 0 MinionPro-Regular Type 1C Custom yes no yes 16 0 MinionMath-Regular Type 1C Custom yes no yes 17 0 RATYCR+MinionPro-Regular CID TrueType Identity-H yes yes yes 1 0 MinionMath-Capt Type 1C Custom yes no yes 59 0 MinionPro-Bold Type 1C Custom yes no yes 68 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2020-11-11 06:14:29 CET RepresentationInformation: pmc_25170515.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2018-01-29 05:45:34 CET Size: 547695 Format: PDF Version: 1.3 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 141 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Info: Title: Author: Subject: BioMed Research International Keywords: Creator: LaTeX with hyperref package Producer: Acrobat Distiller 7.0 (Windows); modified using iTextSharp™ 5.4.0 ©2000-2012 1T3XT BVBA (AGPL-version) CreationDate: Thu Aug 07 10:37:09 CEST 2014 ModDate: Sun Aug 24 13:39:17 CEST 2014 ID: 0xfce6f05ef1ac6a389b35f4f9e50a6cc6, 0x080f3b1f47b18a981029df645a7246f7 Filters: FilterPipeline: FlateDecode Fonts: Type0: Font: BaseFont: RATYCR+MinionPro-Regular Encoding: Identity-H ToUnicode: true Type1: Font: BaseFont: MinionPro-Regular FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MinionPro-Regular Flags: Serif, Symbolic FontBBox: -290, -360, 1684, 989 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: MinionMath-Regular FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MinionMath-Regular Flags: Symbolic FontBBox: 69, -170, 300, 710 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: MinionPro-Bold FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MinionPro-Bold Flags: Symbolic, ForceBold FontBBox: -319, -360, 1684, 1024 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: MinionMath-Capt FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MinionMath-Capt Flags: Symbolic FontBBox: 124, 53, 486, 470 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: MinionPro-It FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MinionPro-It Flags: Serif, Symbolic, Italic FontBBox: -201, -360, 1684, 1002 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: Minion-Black FirstChar: 0 LastChar: 237 FontDescriptor: FontName: Minion-Black Flags: Serif, Nonsymbolic, ForceBold FontBBox: -133, -250, 1120, 827 FontFile3: true Encoding: WinAnsiEncoding CIDFontType2: Font: BaseFont: RATYCR+MinionPro-Regular CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: RATYCR+MinionPro-Regular Flags: Nonsymbolic FontBBox: -289, -360, 1684, 917 FontFile2: true XMP: application/pdfPrevalence of Ischemic Heart Disease and Management of Coronary Risk in Daily Clinical Practice: Results from a Mediterranean Cohort of HIV-Infected PatientsEcheverría, PatriciaDomingo, PereLlibre, Josep-MaríaGutierrez, MarMateo, GraciaPuig, JordiBonjoch, AnnaPérez-Alvarez, NuriaSirera, GuillemClotet, BonaventuraNegredo, EugeniaBackground. There are conflicting data on the prevalence of coronary events and the quality of the management of modifiable cardiovascular risk factors (CVRF) in HIV-infected patients. Methods. We performed a retrospective descriptive study to determine the prevalence of coronary events and to evaluate the management of CVRF in a Mediterranean cohort of 3760 HIV-1-infected patients from April 1983 through June 2011. Results. We identified 81 patients with a history of a coronary event (prevalence 2.15%); 83% of them suffered an acute myocardial infarction. At the time of the coronary event, CVRF were highly prevalent (60.5% hypertension, 48% dyslipidemia, and 16% diabetes mellitus). Other CVRF, such as smoking, hypertension, lack of exercise, and body mass index, were not routinely assessed. After the coronary event, a significant decrease in total cholesterol P=0.025 and LDL-cholesterol P=0.004 was observed. However, the percentage of patients who maintained LDL-cholesterol > 100 mg/dL remained stable (from 46% to 41%, P=0.103). Patients using protease inhibitors associated with a favorable lipid profile increased over time P=0.028. Conclusions. The prevalence of coronary events in our cohort is low. CVRF prevalence is high and their management is far from optimal. More aggressive interventions should be implemented to diminish cardiovascular risk in HIV-infected patients.BioMed Research InternationalHindawi Publishing Corporation2014/08/07Research articledoi:10.1155/2014/823058en Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 50, 705, 171, 713 Page: Label: 2 Page: Label: 3 Page: Label: 4 Page: Label: 5 Page: Label: 6 Page: Label: 7 Page: Label: 8 Checksum: 3c0125da Type: CRC32 Checksum: 55a4f7d566e54f8827ef07e3c54a0132 Type: MD5 Checksum: 01de849d8e65cf5c36d8b4d2ccc4389428336810 Type: SHA-1