f04115e2a19f9082de9e900c5e3f0ebb pmc_25325336.pdf 1d82756e3d8a5a9f62dc1420d7dce8cc29a4c139 pmc_25325336.pdf e7c348efe7359d8bad291b79efdc12317706eaf23f2fb8338cb2163e4dc4b3e8 pmc_25325336.pdf Title: Design of a Customized Multipurpose Nano-Enabled Implantable System for In-Vivo Theranostics Subject: The first part of this paper reviews the current development and key issues on implantable multi-sensor devices for in vivo theranostics. Afterwards, the authors propose an innovative biomedical multisensory system for in vivo biomarker monitoring that could be suitable for customized theranostics applications. At this point, findings suggest that cross-cutting Key Enabling Technologies (KETs) could improve the overall performance of the system given that the convergence of technologies in nanotechnology, biotechnology, micro&nanoelectronics and advanced materials permit the development of new medical devices of small dimensions, using biocompatible materials, and embedding reliable and targeted biosensors, high speed data communication, and even energy autonomy. Therefore, this article deals with new research and market challenges of implantable sensor devices, from the point of view of the pervasive system, and time-to-market. The remote clinical monitoring approach introduced in this paper could be based on an array of biosensors to extract information from the patient. A key contribution of the authors is that the general architecture introduced in this paper would require minor modifications for the final customized bio-implantable medical device. Keywords: implantable multi-sensor; biosensor; biotelemetry; biocompatible; KET; nanomedicine; personalized medicine; innovation Author: Esteve Juanola-Feliu, Pere Ll. Miribel-Català, Cristina Páez Avilés, Jordi Colomer-Farrarons, Manel González-Piñero, Josep Samitier Creator: PScript5.dll Version 5.2.2 Producer: Acrobat Distiller 10.1.7 (Windows) CreationDate: Thu Oct 16 11:38:14 2014 CEST ModDate: Thu Oct 16 11:40:08 2014 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 32 Encrypted: no Page size: 595.22 x 842 pts (A4) Page rot: 0 File size: 2465296 bytes Optimized: no PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- AIKBGJ+TimesNewRoman,Italic TrueType WinAnsi yes yes no 910 0 AIKBHL+TimesNewRoman TrueType WinAnsi yes yes no 911 0 AIKBHN+TimesNewRoman,Bold TrueType WinAnsi yes yes no 912 0 AIKBHP+TimesNewRoman,BoldItalic TrueType WinAnsi yes yes no 913 0 AIKHCM+Arial TrueType WinAnsi yes yes no 503 0 AIKHEO+Arial,Bold TrueType WinAnsi yes yes no 504 0 AIKIHI+Calibri,Bold TrueType WinAnsi yes yes no 505 0 AIKKEN+Symbol Type 1C Custom yes yes yes 507 0 AIKBHK+TimesNewRoman CID TrueType Identity-H yes yes yes 513 0 AIKMLP+Calibri TrueType WinAnsi yes yes no 769 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2020-11-11 06:11:34 CET RepresentationInformation: pmc_25325336.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2018-01-29 05:44:19 CET Size: 2465296 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: ISO PDF/A-1, Level B PDFMetadata: Objects: 931 FreeObjects: 2 IncrementalUpdates: 2 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Info: Title: Design of a Customized Multipurpose Nano-Enabled Implantable System for In-Vivo Theranostics Author: Esteve Juanola-Feliu, Pere Ll. Miribel-Català, Cristina Páez Avilés, Jordi Colomer-Farrarons, Manel González-Piñero, Josep Samitier Subject: The first part of this paper reviews the current development and key issues on implantable multi-sensor devices for in vivo theranostics. Afterwards, the authors propose an innovative biomedical multisensory system for in vivo biomarker monitoring that could be suitable for customized theranostics applications. At this point, findings suggest that cross-cutting Key Enabling Technologies (KETs) could improve the overall performance of the system given that the convergence of technologies in nanotechnology, biotechnology, micro&nanoelectronics and advanced materials permit the development of new medical devices of small dimensions, using biocompatible materials, and embedding reliable and targeted biosensors, high speed data communication, and even energy autonomy. Therefore, this article deals with new research and market challenges of implantable sensor devices, from the point of view of the pervasive system, and time-to-market. The remote clinical monitoring approach introduced in this paper could be based on an array of biosensors to extract information from the patient. A key contribution of the authors is that the general architecture introduced in this paper would require minor modifications for the final customized bio-implantable medical device. 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Miribel-Català, Cristina Páez Avilés, Jordi Colomer-Farrarons, Manel González-Piñero, Josep Samitier Design of a Customized Multipurpose Nano-Enabled Implantable System for In-Vivo Theranostics The first part of this paper reviews the current development and key issues on implantable multi-sensor devices for in vivo theranostics. Afterwards, the authors propose an innovative biomedical multisensory system for in vivo biomarker monitoring that could be suitable for customized theranostics applications. At this point, findings suggest that cross-cutting Key Enabling Technologies (KETs) could improve the overall performance of the system given that the convergence of technologies in nanotechnology, biotechnology, micro&nanoelectronics and advanced materials permit the development of new medical devices of small dimensions, using biocompatible materials, and embedding reliable and targeted biosensors, high speed data communication, and even energy autonomy. Therefore, this article deals with new research and market challenges of implantable sensor devices, from the point of view of the pervasive system, and time-to-market. The remote clinical monitoring approach introduced in this paper could be based on an array of biosensors to extract information from the patient. 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