Index of artpub/2015/203979/

Córdoba, Sarai
Endometrial gene expression profile of pregnant sows with extreme phenotypes for reproductive efficiency
2015 0) and low (L, EBV 0) prolificacy phenotypes. For each sample, mRNA and small RNA libraries were RNA-sequenced, identifying 141 genes and 10 miRNAs differentially expressed between H and L groups. We selected four miRNAs based on their role in reproduction, and five genes displaying the highest differences and a positive mapping into known reproductive QTLs for RT-qPCR validation on the whole extreme population. Significant differences were validated for genes: PTGS2 (p = 0.03; H/L ratio = 3.50), PTHLH (p = 0.03; H/L ratio = 3.69), MMP8 (p = 0.01; H/L ratio = 4.41) and SCNN1G (p = 0.04; H/L ratio = 3.42). Although selected miRNAs showed similar expression levels between H and L groups, significant correlation was found between the expression level of ssc-miR-133a (p 0.01) and sscmiR-92a (p 0.01) and validated genes. These results provide a better understanding of the genetic architecture of prolificacy-related traits and embryo implantation failure in pigs
https://ddd.uab.cat/record/203979

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1=Cordoba,_Sarai	2022-06-29 13:29	16
2=Endometrial_gene_expression_profile_of...	2022-06-29 13:29	105
3=2015_0_and_low_L,_EBV_0_prolificacy_phenotypes....	2022-06-29 13:29	1.0K
4=203979	2022-06-29 13:29	34
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