a11f68e05d8ec80c22c950b13c454197 300287.pdf 4f4fcbc3f45be7fc0915d3ba6b54db61a17f7510 300287.pdf ee7e0e23441e113860678bf94ac320d86c5cd75f43de4f7a0c5c8301959f5646 300287.pdf Title: Rheumatoid arthritis response to treatment across IgG1 allotype – anti-TNF incompatibility: a case-only study Subject: ??? 2015, :. doi:10.1186/s13075-015-0571-z Author: Ariana Montes; Eva Perez-Pampin; Federico Navarro-Sarabia; Virginia Moreira; Arturo Rodríguez de la Serna; Berta Magallares; Yiannis Vasilopoulos; Theologia Sarafidou; Antonio Fernández-Nebro; María del Carmen Ordóñez; Javier Narváez; Juan D Cañete; Ana Marquez; Dora Pascual-Salcedo; Beatriz Joven; Patricia Carreira; Manuel J Moreno-Ramos; Rafael Caliz; Miguel Angel Ferrer; Rosa Garcia-Portales; Francisco J Blanco; Cesar Magro; Enrique Raya; Lara Valor; Juan J Alegre-Sancho; Alejandro Balsa; Javier Martin; Darren Plant; John Isaacs; Ann W Morgan; Anne Barton; Anthony G Wilson; Juan J Gómez-Reino; Antonio Gonzalez Creator: Arbortext Advanced Print Publisher 9.1.440/W Unicode Producer: Acrobat Distiller 10.1.5 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version) CreationDate: Sat Apr 18 10:20:36 2015 CEST ModDate: Mon Apr 27 16:04:14 2015 CEST Custom Metadata: no Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 12 Encrypted: no Page size: 595.276 x 793.701 pts Page rot: 0 File size: 1719263 bytes Optimized: no PDF version: 1.3 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- CNGFOE+MhkxsjAdvTTaf7f9f4f.B Type 1C WinAnsi yes yes no 285 0 CNGFOF+KfkhksAdvTTe45e47d2 Type 1C WinAnsi yes yes no 286 0 CNGFPG+DjhcprAdvTTe45e47d2+20 Type 1C WinAnsi yes yes no 497 0 CNGFPH+LxyjxgAdvTTb5929f4c Type 1C WinAnsi yes yes no 288 0 MyriadPro-Regular Type 1 Custom yes no no 287 0 CNGFPI+NffkywAdvTT99c4c969 Type 1C WinAnsi yes yes no 290 0 CNGGAI+LycxylAdvTT5843c571+03 Type 1C Custom yes yes yes 498 0 CNGKNO+PmvxpgAdvTT7329fd89.I Type 1C WinAnsi yes yes no 291 0 CNGGAK+FwhcqbAdvTTb5929f4c+22 Type 1C Custom yes yes no 318 0 CNGGAJ+YmgcnwAdvTT1b53b5fb.I Type 1C WinAnsi yes yes no 293 0 CNGLCO+TlbrvxAdvTT86d47313 Type 1C WinAnsi yes yes no 289 0 CNGLEO+FdmrwrAdvTT86d47313+20 Type 1C WinAnsi yes yes no 292 0 CNHFHB+VtmgrsAdvTT8861b38f.I Type 1C WinAnsi yes yes no 298 0 CNHGFM+RyxnkmAdvTT86d47313+03 Type 1C Custom yes yes yes 301 0 CNHGKL+VlcvrtAdvTT2cba4af3.B+03 Type 1C Custom yes yes yes 309 0 CNHGKM+KxqbpjAdvTT83913201.I Type 1C WinAnsi yes yes no 306 0 CNHGNM+NtgccwAdvTT86d47313+22 Type 1C Custom yes yes yes 313 0 CNHHGM+PfscvxAdvTT99c4c969+20 Type 1C WinAnsi yes yes no 322 0 CNHHIM+SgpvhdAdvTTb5929f4c+20 Type 1C WinAnsi yes yes no 319 0 CNHHFK+QkkvnqAdvTT5843c571+20 Type 1C Custom yes yes yes 330 0 CNHHFL+FnrwddAdvTTb5929f4c+21 Type 1C Custom yes yes yes 325 0 BkgqdxFrutigerLTStd-Bold Type 1C Custom yes no yes 340 0 DqwkwsFrutigerLTStd-Roman Type 1C Custom yes no yes 335 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-09-26 02:55:32 CEST RepresentationInformation: 300287.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2024-09-25 17:01:04 CEST Size: 1719263 Format: PDF Version: 1.3 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 554 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: Abstract Destination: sectionAbs1 Children: Item: Title: Introduction Destination: sectionASec1 Item: Title: Methods Destination: sectionASec2 Item: Title: Results Destination: sectionASec3 Item: Title: Conclusions Destination: sectionASec4 Item: Title: Introduction Destination: sectionSec1 Item: Title: Methods Destination: sectionSec2 Children: Item: Title: Patients Destination: sectionSec3 Item: Title: G1m allotype genotyping Destination: sectionSec4 Item: Title: Statistical analysis Destination: sectionSec5 Item: Title: Results Destination: sectionSec6 Children: Item: Title: Association in the discovery patient set Destination: sectionSec7 Item: Title: First replication set Destination: sectionSec8 Item: Title: Second replication set Destination: sectionSec9 Item: Title: Combined analysis Destination: sectionSec10 Item: Title: Discussion Destination: sectionSec11 Item: Title: Conclusions Destination: sectionSec12 Item: Title: Appendix Destination: sectionSec13 Item: Title: Additional file Destination: sectionSec14 Item: Title: Abbreviations Destination: sectionabr1 Item: Title: Competing interests Destination: ArtNote1 Item: Title: Authors’ contributions Destination: ArtNote2 Item: Title: Acknowledgements Destination: sections13075-015-0571-z Item: Title: Author details Destination: sectionaunote1 Item: Title: References Destination: sectionBib1 Info: Title: Rheumatoid arthritis response to treatment across IgG1 allotype   anti-TNF incompatibility: a case-only study Author: Ariana Montes; Eva Perez-Pampin; Federico Navarro-Sarabia; Virginia Moreira; Arturo Rodríguez de la Serna; Berta Magallares; Yiannis Vasilopoulos; Theologia Sarafidou; Antonio Fernández-Nebro; María del Carmen Ordóñez; Javier Narváez; Juan D Cañete; Ana Marquez; Dora Pascual-Salcedo; Beatriz Joven; Patricia Carreira; Manuel J Moreno-Ramos; Rafael Caliz; Miguel Angel Ferrer; Rosa Garcia-Portales; Francisco J Blanco; Cesar Magro; Enrique Raya; Lara Valor; Juan J Alegre-Sancho; Alejandro Balsa; Javier Martin; Darren Plant; John Isaacs; Ann W Morgan; Anne Barton; Anthony G Wilson; Juan J Gómez-Reino; Antonio Gonzalez Subject: ??? 2015, :. doi:10.1186/s13075-015-0571-z Creator: Arbortext Advanced Print Publisher 9.1.440/W Unicode Producer: Acrobat Distiller 10.1.5 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version) CreationDate: Sat Apr 18 10:20:36 CEST 2015 ModDate: Mon Apr 27 16:04:14 CEST 2015 ID: 0x4d3d4a8e1ab086d6ebb06049dbee1038, 0x8f00013dff56fe9b3cb86dfd9e0a9b03 Filters: FilterPipeline: FlateDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1100 ImageHeight: 90 ColorSpace: black is zero BitsPerSample: 1 BitsPerSampleUnit: integer Filter: FlateDecode Fonts: Type1: Font: BaseFont: CNGFPH+LxyjxgAdvTTb5929f4c FontSubset: true FirstChar: 32 LastChar: 243 FontDescriptor: FontName: CNGFPH+LxyjxgAdvTTb5929f4c Flags: Nonsymbolic FontBBox: -41, -250, 812, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: CNGLCO+TlbrvxAdvTT86d47313 FontSubset: true FirstChar: 32 LastChar: 243 FontDescriptor: FontName: CNGLCO+TlbrvxAdvTT86d47313 Flags: Serif, Nonsymbolic FontBBox: -218, -239, 1020, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: CNGFPI+NffkywAdvTT99c4c969 FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: CNGFPI+NffkywAdvTT99c4c969 Flags: Nonsymbolic FontBBox: -41, -250, 854, 885 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: CNHHGM+PfscvxAdvTT99c4c969+20 FontSubset: true FirstChar: 32 LastChar: 146 FontDescriptor: FontName: CNHHGM+PfscvxAdvTT99c4c969+20 Flags: Nonsymbolic FontBBox: -218, -197, 1583, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: CNGKNO+PmvxpgAdvTT7329fd89.I FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: CNGKNO+PmvxpgAdvTT7329fd89.I Flags: Nonsymbolic FontBBox: -218, -250, 885, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: CNGLEO+FdmrwrAdvTT86d47313+20 FontSubset: true FirstChar: 32 LastChar: 146 FontDescriptor: FontName: CNGLEO+FdmrwrAdvTT86d47313+20 Flags: Nonsymbolic FontBBox: -218, -218, 1291, 812 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: CNGGAJ+YmgcnwAdvTT1b53b5fb.I FontSubset: true FirstChar: 32 LastChar: 118 FontDescriptor: FontName: CNGGAJ+YmgcnwAdvTT1b53b5fb.I Flags: Nonsymbolic FontBBox: -114, -250, 864, 854 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: CNHHFL+FnrwddAdvTTb5929f4c+21 FontSubset: true FirstChar: 1 LastChar: 2 FontDescriptor: FontName: CNHHFL+FnrwddAdvTTb5929f4c+21 Flags: Symbolic FontBBox: -20, -208, 1208, 895 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: CNHFHB+VtmgrsAdvTT8861b38f.I FontSubset: true FirstChar: 32 LastChar: 118 FontDescriptor: FontName: CNHFHB+VtmgrsAdvTT8861b38f.I Flags: Nonsymbolic FontBBox: -187, -239, 1062, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: CNHHFK+QkkvnqAdvTT5843c571+20 FontSubset: true FirstChar: 1 LastChar: 2 FontDescriptor: FontName: CNHHFK+QkkvnqAdvTT5843c571+20 Flags: Symbolic FontBBox: -208, -208, 1062, 864 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: CNHGFM+RyxnkmAdvTT86d47313+03 FontSubset: true FirstChar: 1 LastChar: 2 FontDescriptor: FontName: CNHGFM+RyxnkmAdvTT86d47313+03 Flags: Symbolic FontBBox: -135, -250, 906, 822 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: DqwkwsFrutigerLTStd-Roman FirstChar: 32 LastChar: 121 FontDescriptor: FontName: DqwkwsFrutigerLTStd-Roman Flags: Symbolic FontBBox: -169, -250, 1000, 935 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: CNGFPG+DjhcprAdvTTe45e47d2+20 FontSubset: true FirstChar: 32 LastChar: 150 FontDescriptor: FontName: CNGFPG+DjhcprAdvTTe45e47d2+20 Flags: Nonsymbolic FontBBox: -218, -197, 1302, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: CNGGAI+LycxylAdvTT5843c571+03 FontSubset: true FirstChar: 1 LastChar: 2 FontDescriptor: FontName: CNGGAI+LycxylAdvTT5843c571+03 Flags: Symbolic FontBBox: -437, -229, 875, 885 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: CNHGKM+KxqbpjAdvTT83913201.I FontSubset: true FirstChar: 32 LastChar: 118 FontDescriptor: FontName: CNHGKM+KxqbpjAdvTT83913201.I Flags: Nonsymbolic FontBBox: -93, -250, 906, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: BkgqdxFrutigerLTStd-Bold FirstChar: 32 LastChar: 147 FontDescriptor: FontName: BkgqdxFrutigerLTStd-Bold Flags: Symbolic, ForceBold FontBBox: -166, -250, 1000, 935 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: CNHGKL+VlcvrtAdvTT2cba4af3.B+03 FontSubset: true FirstChar: 1 LastChar: 2 FontDescriptor: FontName: CNHGKL+VlcvrtAdvTT2cba4af3.B+03 Flags: Symbolic FontBBox: -500, -208, 916, 885 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: CNHGNM+NtgccwAdvTT86d47313+22 FontSubset: true FirstChar: 2 LastChar: 22 FontDescriptor: FontName: CNHGNM+NtgccwAdvTT86d47313+22 Flags: Symbolic FontBBox: -166, -270, 1031, 906 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: CNGFOE+MhkxsjAdvTTaf7f9f4f.B FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: CNGFOE+MhkxsjAdvTTaf7f9f4f.B Flags: Nonsymbolic FontBBox: -218, -250, 875, 895 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: CNGGAK+FwhcqbAdvTTb5929f4c+22 FontSubset: true FirstChar: 21 LastChar: 22 FontDescriptor: FontName: CNGGAK+FwhcqbAdvTTb5929f4c+22 Flags: Nonsymbolic FontBBox: -10, -218, 1083, 906 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: CNGFOF+KfkhksAdvTTe45e47d2 FontSubset: true FirstChar: 32 LastChar: 122 FontDescriptor: FontName: CNGFOF+KfkhksAdvTTe45e47d2 Flags: Nonsymbolic FontBBox: -218, -250, 833, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: MyriadPro-Regular FirstChar: 1 LastChar: 255 FontDescriptor: FontName: MyriadPro-Regular Flags: Nonsymbolic FontBBox: -46, -250, 1126, 879 FontFile: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: CNHHIM+SgpvhdAdvTTb5929f4c+20 FontSubset: true FirstChar: 32 LastChar: 150 FontDescriptor: FontName: CNHHIM+SgpvhdAdvTTb5929f4c+20 Flags: Nonsymbolic FontBBox: -218, -208, 1375, 864 FontFile3: true Encoding: WinAnsiEncoding XMP: ??? 2015, :. doi:10.1186/s13075-015-0571-z 2015-04-18T16:20:36+08:00 Arbortext Advanced Print Publisher 9.1.440/W Unicode 2015-04-27T16:04:14+02:00 2015-04-27T16:04:14+02:00 application/pdf http://dx.doi.org/10.1186/s13075-015-0571-z ??? © 2015 Montes et al.; licensee BioMed Central. ??? 2015, :. doi:10.1186/s13075-015-0571-z Rheumatoid arthritis response to treatment across IgG1 allotype – anti-TNF incompatibility: a case-only study Ariana Montes; Eva Perez-Pampin; Federico Navarro-Sarabia; Virginia Moreira; Arturo Rodríguez de la Serna; Berta Magallares; Yiannis Vasilopoulos; Theologia Sarafidou; Antonio Fernández-Nebro; María del Carmen Ordóñez; Javier Narváez; Juan D Cañete; Ana Marquez; Dora Pascual-Salcedo; Beatriz Joven; Patricia Carreira; Manuel J Moreno-Ramos; Rafael Caliz; Miguel Angel Ferrer; Rosa Garcia-Portales; Francisco J Blanco; Cesar Magro; Enrique Raya; Lara Valor; Juan J Alegre-Sancho; Alejandro Balsa; Javier Martin; Darren Plant; John Isaacs; Ann W Morgan; Anne Barton; Anthony G Wilson; Juan J Gómez-Reino; Antonio Gonzalez True ??? 10.1186/s13075-015-0571-z © 2015 Montes et al.; licensee BioMed Central. ??? journal ??? Acrobat Distiller 10.1.5 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version) uuid:c9d1f2ba-9fdf-412c-a07a-887fb60252c9 uuid:e166586a-8433-4715-8848-09ee52bedf3a default 1 converted uuid:c9d1f2ba-9fdf-412c-a07a-887fb60252c9 converted to PDF/A-1b pdfToolbox 2015-04-25T05:48:49+08:00 1 B http://ns.adobe.com/pdf/1.3/ pdf Adobe PDF Schema internal A name object indicating whether the document has been modified to include trapping information Trapped Text http://ns.adobe.com/xap/1.0/mm/ xmpMM XMP Media Management Schema internal UUID based identifier for specific incarnation of a document InstanceID URI internal The common identifier for all versions and renditions of a document. OriginalDocumentID URI http://www.aiim.org/pdfa/ns/id/ pdfaid PDF/A ID Schema internal Part of PDF/A standard part Integer internal Amendment of PDF/A standard amd Text internal Conformance level of PDF/A standard conformance Text http://ns.adobe.com/xap/1.0/ xmp XMP Basic external A word or short phrase that identifies a document as a member of a user-defined collection. Used to organize documents in a file browser. Label Text http://prismstandard.org/namespaces/basic/2.0/ prism Prism external The aggregation type specifies the unit of aggregation for a content collection. Comment PRISM recommends that the PRISM Aggregation Type Controlled Vocabulary be used to provide values for this element. Note: PRISM recommends against the use of the #other value currently allowed in this controlled vocabulary. In lieu of using #other please reach out to the PRISM group at info@prismstandard.org to request addition of your term to the Aggregation Type Controlled Vocabulary. aggregationType Text external Copyright copyright Text external The Digital Object Identifier for the article. The DOI may also be used as the dc:identifier. If used as a dc:identifier, the URI form should be captured, and the bare identifier should also be captured using prism:doi. If an alternate unique identifier is used as the required dc:identifier, then the DOI should be specified as a bare identifier within prism:doi only. If the URL associated with a DOI is to be specified, then prism:url may be used in conjunction with prism:doi in order to provide the service endpoint (i.e. the URL). doi Text external ISSN for an electronic version of the issue in which the resource occurs. Permits publishers to include a second ISSN, identifying an electronic version of the issue in which the resource occurs (therefore e(lectronic)Issn. If used, prism:eIssn MUST contain the ISSN of the electronic version. See prism:issn. issn Text external Title of the magazine, or other publication, in which a resource was/will be published. Typically this will be used to provide the name of the magazine an article appeared in as metadata for the article, along with information such as the article title, the publisher, volume, number, and cover date. Note: Publication name can be used to differentiate between a print magazine and the online version if the names are different such as “magazine” and “magazine.com.” publicationName Text external This element provides the url for an article or unit of content. The attribute platform is optionally allowed for situations in which multiple URLs must be specified. PRISM recommends that a subset of the PCV platform values, namely “mobile” and “web”, be used in conjunction with this element. NOTE: PRISM recommends against the use of the #other value allowed in the PRISM Platform controlled vocabulary. In lieu of using #other please reach out to the PRISM group at prism-wg@yahoogroups.com to request addition of your term to the Platform Controlled Vocabulary. url Text Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 114, 155, 251, 162 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 264, 67, 379, 74 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 201, 51, 340, 58 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 162, 646, 167, 656 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 207, 586, 211, 596 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 189, 562, 194, 572 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 196, 562, 201, 572 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 91, 526, 96, 536 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 100, 526, 105, 536 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 106, 478, 111, 488 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 114, 478, 124, 488 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 334, 682, 344, 692 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 346, 682, 356, 692 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 358, 682, 368, 692 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 476, 634, 486, 644 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 490, 634, 500, 644 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 359, 562, 363, 572 Flags: Print AppearanceDictionary: true Destination: 3 Annotation: Subtype: Link Rect: 460, 538, 469, 548 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 471, 538, 481, 548 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 419, 478, 428, 488 Flags: Print AppearanceDictionary: true Destination: 244 Thumb: true Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 59, 658, 69, 668 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 71, 658, 81, 668 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 83, 658, 92, 668 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 94, 658, 104, 668 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 59, 622, 69, 632 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 105, 574, 115, 584 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 118, 574, 128, 584 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 131, 574, 141, 584 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 151, 538, 161, 548 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 163, 538, 173, 548 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 251, 514, 256, 524 Flags: Print AppearanceDictionary: true Destination: 3 Annotation: Subtype: Link Rect: 233, 502, 243, 512 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 245, 502, 254, 512 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 131, 478, 141, 488 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 143, 478, 152, 488 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 143, 430, 153, 440 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 156, 430, 165, 440 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 394, 574, 399, 584 Flags: Print AppearanceDictionary: true Destination: 48 Annotation: Subtype: Link Rect: 477, 454, 482, 464 Flags: Print AppearanceDictionary: true Destination: 48 Thumb: true Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 87, 562, 127, 572 Flags: Print AppearanceDictionary: true Destination: 235 Annotation: Subtype: Link Rect: 264, 502, 273, 512 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 275, 502, 285, 512 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 242, 382, 247, 392 Flags: Print AppearanceDictionary: true Destination: 3 Annotation: Subtype: Link Rect: 236, 298, 241, 308 Flags: Print AppearanceDictionary: true Destination: 235 Annotation: Subtype: Link Rect: 198, 226, 203, 236 Flags: Print AppearanceDictionary: true Destination: 121 Annotation: Subtype: Link Rect: 214, 130, 224, 140 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 364, 634, 374, 644 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 449, 562, 454, 572 Flags: Print AppearanceDictionary: true Destination: 121 Annotation: Subtype: Link Rect: 492, 322, 497, 332 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 486, 286, 491, 296 Flags: Print AppearanceDictionary: true Destination: 235 Annotation: Subtype: Link Rect: 370, 250, 375, 260 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 480, 178, 485, 188 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 466, 106, 470, 116 Flags: Print AppearanceDictionary: true Destination: 235 Thumb: true Page: Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 255, 154, 260, 164 Flags: Print AppearanceDictionary: true Destination: 121 Annotation: Subtype: Link Rect: 280, 154, 285, 164 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 353, 106, 358, 116 Flags: Print AppearanceDictionary: true Destination: 147 Annotation: Subtype: Link Rect: 479, 70, 483, 80 Flags: Print AppearanceDictionary: true Destination: 147 Thumb: true Page: Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 72, 490, 77, 500 Flags: Print AppearanceDictionary: true Destination: 235 Annotation: Subtype: Link Rect: 159, 382, 164, 392 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 372, 442, 376, 452 Flags: Print AppearanceDictionary: true Destination: 147 Annotation: Subtype: Link Rect: 460, 382, 465, 392 Flags: Print AppearanceDictionary: true Destination: 235 Thumb: true Page: Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 258, 418, 263, 428 Flags: Print AppearanceDictionary: true Destination: 147 Annotation: Subtype: Link Rect: 118, 274, 123, 284 Flags: Print AppearanceDictionary: true Destination: 147 Annotation: Subtype: Link Rect: 383, 442, 388, 452 Flags: Print AppearanceDictionary: true Destination: 235 Thumb: true Page: Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 199, 178, 209, 188 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 59, 94, 69, 104 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 71, 94, 81, 104 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 414, 682, 423, 692 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 425, 682, 435, 692 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 439, 682, 448, 692 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 403, 622, 412, 632 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 502, 490, 512, 500 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 514, 490, 523, 500 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 525, 490, 535, 500 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 336, 466, 346, 476 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 445, 430, 455, 440 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 409, 382, 419, 392 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 421, 382, 431, 392 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 433, 382, 442, 392 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 326, 358, 336, 368 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 338, 358, 347, 368 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 349, 358, 359, 368 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 361, 358, 370, 368 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 373, 358, 382, 368 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 387, 298, 397, 308 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 445, 202, 455, 212 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 420, 154, 430, 164 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 307, 58, 317, 68 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 319, 58, 328, 68 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 332, 58, 341, 68 Flags: Print AppearanceDictionary: true Destination: 244 Thumb: true Page: Sequence: 9 Annotations: Annotation: Subtype: Link Rect: 130, 682, 140, 692 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 170, 646, 179, 656 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 181, 646, 191, 656 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 133, 550, 143, 560 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 145, 550, 155, 560 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 152, 478, 157, 488 Flags: Print AppearanceDictionary: true Destination: 48 Annotation: Subtype: Link Rect: 186, 106, 195, 116 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 116, 58, 121, 68 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 437, 694, 441, 704 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 473, 490, 483, 500 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 415, 370, 425, 380 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 505, 334, 515, 344 Flags: Print AppearanceDictionary: true Destination: 259 Annotation: Subtype: Link Rect: 388, 238, 398, 248 Flags: Print AppearanceDictionary: true Destination: 244 Annotation: Subtype: Link Rect: 400, 238, 410, 248 Flags: Print AppearanceDictionary: true Destination: 259 Annotation: Subtype: Link Rect: 414, 238, 424, 248 Flags: Print AppearanceDictionary: true Destination: 259 Annotation: Subtype: Link Rect: 346, 202, 356, 212 Flags: Print AppearanceDictionary: true Destination: 259 Annotation: Subtype: Link Rect: 447, 178, 456, 188 Flags: Print AppearanceDictionary: true Destination: 259 Thumb: true Page: Sequence: 10 Annotations: Annotation: Subtype: Link Rect: 61, 247, 151, 254 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 11 Annotations: Annotation: Subtype: Link Rect: 319, 268, 390, 275 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 12 Annotations: Annotation: Subtype: Link Rect: 152, 668, 270, 675 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 71, 659, 112, 666 Flags: Print AppearanceDictionary: true Thumb: true Checksum: b464cd1b Type: CRC32 Checksum: a11f68e05d8ec80c22c950b13c454197 Type: MD5 Checksum: 4f4fcbc3f45be7fc0915d3ba6b54db61a17f7510 Type: SHA-1 Checksum: ee7e0e23441e113860678bf94ac320d86c5cd75f43de4f7a0c5c8301959f5646 Type: SHA-256