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Title:          Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma
Subject:        Nature Communications 7,  (2016). doi:10.1038/ncomms12451
Author:         Kouya Shiraishi
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        Title: Results
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          Title: GWAS on the risk for LADC with EGFR mutations
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          Title: Validation study
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          Title: Differential association by EGFR mutation
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          Title: Imputation analysis of the HLA class II locus
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          Title: Imputation analysis of the FOXP4 locus
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        Title: Figure™1Regional plots of variations in the HLA class II region.Plots show results of association studies of (a) nominal analysis, (b) conditioned analysis on rs3817963 and (c) conditioned analysis on rs2179920. Red line shows the level of genome-wide sig
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        Title: Figure™2Regional plot of variations in the FOXP4 region.The marker SNP is shown in purple and the r2 values for the other SNPs are indicated by different colours. Correlations were estimated using data from the 1000 Genomes Project. Genes within the regio
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          Title: Sample preparation and genotyping
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          Title: Detection of EGFR mutations
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          Title: Association study of the rs7741164 SNP
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          Title: Expression analysis of non-cancerous lung tissues
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          Title: Data availability
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        Title: Clinical Lung Cancer Genome PNetwork Genomic MA genomics-based classification of human lung tumorsSci. Transl. Med.5209ra1532013Cancer Genome Atlas Research NComprehensive molecular profiling of lung adenocarcinomaNature5115435502014KohnoT.KIF5B-RET fusio
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        Title: We thank all of the subjects for participating in the study. We are grateful to the members of the National Cancer Center Biobank, BioBank Japan and the Rotary Club of Osaka-Midosuji District 2660 Rotary International in Japan for supporting our study. We
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