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Title:          Carbon nanotubes allow capture of krypton, barium and lead for multichannel biological X-ray fluorescence imaging
Subject:        Nature Communications 7,  (2016). doi:10.1038/ncomms13118
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        Title: Results
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         Item: 
          Title: Design of XRF nanobottle contrast agents
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          Title: Construction and characterization of nanobottles
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          Title: Functionalization of nanobottles for cellular targeting
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        Title: Figure™1Design of XRF-contrast carrier systems to probe cellular organelles through XRF mapping.By filling, sealing and modifying CNTs, ’nanobottleCloseCurlyQuote systems with targeting ligands can be created based upon almost any appropriate elemental sy
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        Title: Figure™2Characterization of filled SWCNTs, and functionalization with targeting peptides.(a) HR-TEM characterization of filled SWCNTs (scale bars, 10thinspnm). HAADF-STEM images show bright lines indicating filling with highdashZ species for PbO@SWCNT and
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          Title: Cellular microscopy of XRF nanobottle contrast agents
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        Title: Figure™3Intracellular tracking of peptide-functionalized SWCNT nanobottles.Maps of the SWCNT Raman G- band (1,500-1,650thinspcm-1) were recorded within the dashed boxes. In the HAADF-STEM images, SWCNTs can be identified by high-contrast regions speckled 
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        Title: Discussion
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        Title: Figure™4Use of filled and decorated SWCNTs as biological XRF contrast agents.(a) Elemental distribution maps of untreated HeLa cells. Three biologically relevant channels are presented to show the cell features. Sulfur was chosen as the best maker of cell
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        Title: Methods
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          Title: Purification and opening of CNTs
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          Title: PbO@SWCNT
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          Title: BaI2@SWCNT
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          Title: Kr@SWCNT
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          Title: General method for attachment of maleimide linker to SWCNTs
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         Item: 
          Title: General prep for CNT peptide appendage and Fmoc cleavage
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          Title: Cell studies
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         Item: 
          Title: MTS assay
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         Item: 
          Title: Preparation of sapphire discs for XRFsolRaman imaging of cells
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         Item: 
          Title: Raman imaging
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         Item: 
          Title: Preparation of cell samples for STEM imaging
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          Title: XRF imaging
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          Title: Data availability
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       Item: 
        Title: PushieM. J.PickeringI. J.KorbasM.HackettM. J.GeorgeG. N.Elemental and chemically specific X- ray fluorescence imaging of biological systemsChem. Rev.114849985412014HuangJ. G.LeshukT.GuF. X.Emerging nanomaterials for targeting subcellular organellesNano To
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       Item: 
        Title: C.J.S., R.N.R., S.D.M., M.M., M.K., E.P., B.B., G.T. and B.G.D. were supported by the European Commission FP7-ITN RADDEL (contract number 290023). R.R. was supported by a Felix scholarship. K.W. was supported by a Margaret Pelly scholarship. We are gratef
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        Title: ACKNOWLEDGEMENTS
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   Type: CRC32
  Checksum: 675f765d2a9c75051a07e6c93a2bdf0c
   Type: MD5
  Checksum: 48dcf66ebded5ae88985890e5709b987f47a1778
   Type: SHA-1