6f817399b5f0b1defa00da22bc8b478d VetRes_a2016v47p104.pdf 8856b2ebddc9651d2a0ce89921284162f66cc487 VetRes_a2016v47p104.pdf 307d14f81988ce4f6eb9068e665a406b530bf76dd739d96c44353eebdc94cb8d VetRes_a2016v47p104.pdf Title: Distinct functional enrichment of transcriptional signatures in pigs with high and low IFN-gamma responses after vaccination with a porcine reproductive and respiratory syndrome virus (PRRSV) Subject: Veterinary Research, doi:10.1186/s13567-016-0392-3 Author: Tahar Ait-Ali Creator: Springer Producer: iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version) CreationDate: Tue Oct 18 16:04:44 2016 CEST ModDate: Thu Oct 20 13:17:16 2016 CEST Tagged: no UserProperties: no Suspects: no Form: AcroForm JavaScript: no Pages: 12 Encrypted: no Page size: 595.276 x 790.866 pts Page rot: 0 File size: 1530365 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- 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DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: EN Outlines: Item: Title: Distinct functional enrichment of transcriptional signatures in pigs with high and low IFN-gamma responses after vaccination with a porcine reproductive and respiratory syndrome virus (PRRSV) Children: Item: Title: Abstract Item: Title: Introduction Item: Title: Materials and methods Children: Item: Title: Animals and study design Item: Title: Peripheral blood mononuclear cell isolation Item: Title: ELISPOT assays Item: Title: Humoral response Item: Title: In vitro treatment of peripheral blood mononuclear cells Item: Title: RNA extraction Item: Title: Microarray platform and data analysis Item: Title: Quantitative real time RT-PCR validation (qRT-PCR) Item: Title: Gene ontology and pathway analysis Item: Title: Statistical analysis Item: Title: Results Children: Item: Title: Characterization of the humoral response in HR and LR pigs Item: Title: Host transcript regulation during PRRSV vaccine challenge Item: Title: Validation of differentially regulated transcripts using quantitative real time PCR (qRT-PCR) Item: Title: Gene ontology analyses Item: Title: Upstream regulators using Ingenuity pathway analysis (IPA) Item: Title: Discussion Item: Title: Competing interests Item: Title: References Info: Title: Distinct functional enrichment of transcriptional signatures in pigs with high and low IFN-gamma responses after vaccination with a porcine reproductive and respiratory syndrome virus (PRRSV) Author: Tahar Ait-Ali Subject: Veterinary Research, doi:10.1186/s13567-016-0392-3 Creator: Springer Producer: iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version) CreationDate: Tue Oct 18 16:34:44 CEST 2016 ModDate: Thu Oct 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functional enrichment of transcriptional signatures in pigs with high and low IFN-gamma responses after vaccination with a porcine reproductive and respiratory syndrome virus (PRRSV) Tahar Ait-Ali Ivan Díaz Ferran Soldevila Esmeralda Cano Yanli Li Alison D. Wilson Bruno Giotti Alan L. 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